• 한국IT서비스학회지
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• 제6권1호
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• pp.1-15
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• 2007

An objective and valid knowledge activity indicator (KAI) is essential for encouraging knowledge activity in public institution. However, knowledge activity of public institution is inherently different from one of private corporation and, therefore, new method to find aggregated knowledge mileage considering public organizational culture and structure is to be developed. Therefore, this paper shows how to develop KAI of public institution based on three steps. First, knowledge activities were categorized as knowledge creation, knowledge sharing, and knowledge value increasing. Several knowledge indicators and hierarchical knowledge structure were developed for each knowledge categories. Second, personal knowledge mileage was calculated using AHP method considering whole organization's opinion. Finally, these approaches to find KAI were applied to "P" public institution as case studies. The results shows that KAI developed in this paper was very effective in grouping knowledge workers based on knowledge activities.

• Journal of Information Processing Systems
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• 제14권6호
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• pp.1405-1419
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• 2018

An image fusion method is proposed on the basis of depth model segmentation to overcome the shortcomings of noise interference and artifacts caused by infrared and visible image fusion. Firstly, the deep Boltzmann machine is used to perform the priori learning of infrared and visible target and background contour, and the depth segmentation model of the contour is constructed. The Split Bregman iterative algorithm is employed to gain the optimal energy segmentation of infrared and visible image contours. Then, the nonsubsampled contourlet transform (NSCT) transform is taken to decompose the source image, and the corresponding rules are used to integrate the coefficients in the light of the segmented background contour. Finally, the NSCT inverse transform is used to reconstruct the fused image. The simulation results of MATLAB indicates that the proposed algorithm can obtain the fusion result of both target and background contours effectively, with a high contrast and noise suppression in subjective evaluation as well as great merits in objective quantitative indicators.

• Biomolecules & Therapeutics
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• 제32권2호
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• pp.183-191
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• 2024

The Unfolded Protein Response (UPR) serves as a critical cellular mechanism dedicated to maintaining protein homeostasis, primarily within the endoplasmic reticulum (ER). This pathway diligently responds to a variety of intracellular indicators of ER stress with the objective of reinstating balance by diminishing the accumulation of unfolded proteins, amplifying the ER's folding capacity, and eliminating slow-folding proteins. Prolonged ER stress and UPR irregularities have been linked to a range of neuropsychiatric disorders, including major depressive disorder, bipolar disorder, and schizophrenia. This review offers a comprehensive overview of the UPR pathway, delineating its activation mechanisms and its role in the pathophysiology of neuropsychiatric disorders. It highlights the intricate interplay within the UPR and its profound influence on brain function, synaptic perturbations, and neural developmental processes. Additionally, it explores evolving therapeutic strategies targeting the UPR within the context of these disorders, underscoring the necessity for precision and further research to effective treatments. The research findings presented in this work underscore the promising potential of UPR-focused therapeutic approaches to address the complex landscape of neuropsychiatric disorders, giving rise to optimism for improving outcomes for individuals facing these complex conditions.

• 한국융합학회논문지
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• 제10권1호
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• pp.187-195
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• 2019

현대 기업에 있어서 기업 내외부에 발생하는 상호작용에 대한 객관적이며 계량화된 성과측정 방법론에 중요성이 강조되고 있다. 이러한 현상의 원인은 기업에 대한 객관적인 평가를 통한 기업의 현재가치와 현재의 에너지 상태를 가늠하여 미래 지향적인 전략의 수립과 실천의 중요성이 있기 때문이다. 이에 따라 최근 들어 부각되고 있는 객관적 성과측정 방법론인 BSC(Balance Scorecard)를 사용한 성과지표로써의 KPI 선정이 매우 중요시되고 있다. 기존 KPI에 대한 많은 연구들이 여러 산업 군에서 이루어져 있지만, SI 기업에 대한 KPI 연구는 미비한 실정이었다. 본 연구에서는 SI 기업에 적용될 수 있는 KPI를 발굴하는데 초점을 맞추고 있다. SI 기업들의 일반적인 전략에 따른 KPI 설계체계에 대한 연구와 조직군별 평가지표 개발에 따른 방법론과 평가지표개발에 대한 연구를 진행 하였으며, 아울러 각각의 평가지표에 따른 가중치 적용 방법론을 제시하였다.

• 한국치위생학회지
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• 제19권1호
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• pp.65-78
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• 2019

Objectives: This study was conducted to characterize the impact of cognitive function and oral health status on mastication in senior citizens, ${\geq}65$ years of age, using senior centers in the city of Wonju, South Korea. Methods: A cross-sectional study consisting of a simple oral examination and survey questionnaires was performed in 154 individuals. General characteristics, subjective masticatory function, objective masticatory function, cognitive function, and oral health status were collected as variables. Correlation and multiple linear regression analyses were conducted. A p-value of <0.05 was considered to be statistically significant. Results: The subjective masticatory function was scored using the 5-point Likert scale. When subjective masticatory function was analyzed in groups according to cognitive function, the mean subjective masticatory function scores were 4.31, 4.09, and 3.29 in the normal group (cognitive score of ${\geq}16$), suspected dementia group (cognitive score of 1215), and mild dementia group (cognitive score of ${\leq}11$), respectively. Thus, subjective masticatory function decreased along with decreasing cognitive function. When cognitive function, subjective masticatory function, and objective masticatory function were compared with indicators of oral health status (number of functional teeth, oral dryness), subjective masticatory function exhibited a significant positive correlation with objective masticatory function (r=0.635, p<0.01), cognitive function (r=0.292, p<0.01), and total number of functional teeth, including prosthetic appliances (dentures) (r=0.305, p<0.01). According to the regression analysis, age, sex, number of functional teeth, and cognitive function affected subjective masticatory function. Conclusions: The results of this study revealed that age, sex, number of functional teeth, and cognitive function affected subjective masticatory function, whereas oral dryness did not. Therefore, dental professionals must consider subjective masticatory function when providing oral care in senior patients with low cognitive function.

• Animal Bioscience
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• 제35권1호
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• pp.147-152
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• 2022

Objective: This study was conducted to obtain an objective index that can be quantified and used for establishing an animal welfare certification standard in Korea. For this purpose rumen pH, ruminating time, milk yield, milk quality, and blood components of cows reared in farms feeding high forage level (90%) and farms feeding low forage level (40%) were compared. Methods: Data on rumen pH, rumination time, milk yield, milk fat ratio, milk protein ratio, and blood metabolism were collected from 12 heads from a welfare farm (forage rate 88.5%) and 13 heads from a conventional farm (forage rate 34.5%) for three days in October 2019. Results: The rumination time was longer in cattle on the welfare farm than on the conventional farm (p<0.01), but ruminal pH fluctuation was greater in the cattle on conventional farm than the welfare farm (p<0.01). Conventional farms with a high ratio of concentrated feed were higher in average daily milk yield than welfare farms, but milk fat and milk production efficiency (milk fat and milk protein corrected milk/total digestible nutrients) was higher in cattle on welfare farms. Blood test results showed a normal range for both farm types, but concentrations of total cholesterol and non-esterified fatty acid were significantly higher in cows from conventional farms with a high milk yield (p<0.01). Conclusion: The results of this study confirmed that cows on the animal welfare farm with a high percentage of grass feed had higher milk production efficiency with healthier rumen pH and blood metabolism parameters compared to those on the conventional farm.

• 상하수도학회지
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• 제21권4호
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• pp.453-465
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• 2007

With rapid expansion of the water market and growth of water companies, the recent trends in international water industry show that standardization of service activities concerning management of water and wastewater system (ISO/TC 224, to be issued in the second half year of 2007) is expected to have a large influence on the global water market including liberalization of water service market. In the Draft International Standard(DIS) of ISO/TC224, Performance Indicators(PIs) are suggested to estimate the service activities relating to water and wastewater treatment facilities. PIs have been developed in many countries including some international organization(World Bank, IWA and etc.) for service benchmarking. To evaluate public service level and establish plans to improve service level of wastewater utilities, we developed PIs for 120 items and applied them to 10 sewage utilities in the consideration of their scales, circumstances and conditions. In this study, we verified the applicability of the developed performance indicators(PIs). So, we concluded that PIs developed for the purpose of this study can be a useful tool applicable to objective evaluation of the service level of sewage utilities. Using the evaluation tool of PIs developed, it can also be used as a benchmarking tool in this industry as well as for enhancing the efficiency of operation and management of the sewage system. It will also contribute to the water resource management through determination of investment priorities based on the evaluation results and to raising international competitiveness of the domestic sewage utilities to meet the future opening of the water market.

• Spatial Information Research
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• 제8권2호
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• pp.233-241
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• 2000

The objective of this study were to develop landscape scale ecosystem assessment model, and apply the model for the assessment of the state and change of ecosystem of the study area, Yongin, Korea. Since natural ecosystem of the site has been deteriorated significantly during recent extensive residential development, it is essential to correctly assess ecosystem of the study site. Traditional ecosystem assessment mainly utilizing intensive field survey requires high cost, but the outcome rarely represents spatial pattern of the regional ecosystems. Ecosystem assesment of landscape scale based on landscape ecology can resolve most of the shortfalls of the traditional approach. The research method can be summarized as follows. First, extensive literature review on such topics as spatial pattern of ecosystem, ecosystem assessment of landscape scale, ecological analysis was carried out. Second, a model for the ecosystem assessment of landscape scale emphasizing spatial pattern of ecosystem was developed. This model evaluates three indicators; ecological integrity and biological diversity, watershed integrity, and landscape resilience of 11 watersheds in the study area. Finally, ecological assessment utilizing two sets of indicators, enhancement of and disturbance of ecosystem stability, was carried out. This assessment method is based on Environmental Monitoring and Assessment Program´s Landscape component(EMAP-L) of EPA(1994). The results of this study are as follows. First, the ecosystem assessment of landscape scale of the study area of Yongin, Korea, showed that escosystems of Tanchun01 and Chungmichun01 watersheds had the worst state in the study site in 1991. On the other hand, the ecosystems of Jinwechun01, Kyunganchun02, and Bokhachun01 watersheds had the most stable ecosystem in 1991. Second, ecosystems of Tanchun01, Shingal reservoir, and Kyunganchun01 watersheds were evaluated to be the worst state in the study site in 1996. And, ecosystems of Jinwechun01 and Gosam reservoir watersheds had the most stable ecosystem. Third, ecosystem of Tanchun01 watershed which incudes Suji residential development project site changed the most drastically between 1991 and 1996. The ecosystem of the watershed the most drastically deteriorated due to it´s proximity to Seoul and Bundang new town.

• 보건행정학회지
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• 제5권2호
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• pp.155-172
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• 1995

This study is an empirical analysis on the equity in the delivery of heatlh care under the Korean Medical Insurance Corporation System. The purposes of this study are to find out effects of income on the health care utiliztion and measure the income-related inequity in the distribution of health care. This study was carried out based on the fact that the health insurance program has been organized to achieve the equity objective, "equal treatment for equal needs". Of 41, 828 insured persons who had been diagnosed in the 1993 Health Screening Test and utilifzation data from 1, January 1993 through 31, December 1993 were derived from the Benefit Managment File. Inequity was measured by means of I) share approach, ii) standardization concentration curve approach, iii) inequity index, iv) test for inequity. The major findings were as follows : 1. The expenditure shares of the top two quintile groups exceeded their morbidity shares, whereas the opposite was true of the bottom three quintile groups, Which showed a positive HI$_{LG}$ inequity index, suggesting the presence of some inequity favoring the rich group. 2. Compared with other residential areas, the rural area showed the highest positive HI$_{LG}$ irrespective of need indicatior applied. 3. Standardized expenditure concentration indices adjusted by age, gender and need structure were also found to be positive, and therefore still indicated that there has been inequity favoring the rich after the standardization. 4. The Loglikelihood Ratio (LR) test for the statistical significance of income-related inequity of medical care utilization was carried out using the logistic regression model. The resulting loglikelihood ratio test statistic value was 176, which did exceed the 0.5 percent critical value of the chi-square distribution with 28 degrees of freedom, which is 50.993. Therefore, the null hypothesis of no income-related inequity of medical care utilization was rejected at the 99.5 percent confidence level. 5. The Regression based F-test has been carried out for analyzing the income-related inequity of medical expenditure in terms of age, gender, morbidity indicators as explanary variables. The hypothesis of the absence of income-relate inequity was rejected for all need indicators at the 95% confidence level.nce level.

• Journal of Ecology and Environment
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• 제35권4호
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• pp.323-329
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• 2012

The Standardized Precipitation Index (SPI) is a widely used drought index to provide good estimations of the intensity, magnitude and spatial extent of droughts. The objective of this study was to analyze the spatial pattern of drought by SPI index. In this paper, the patterns of drought hazard in Iran are evaluated according to the data of 40 weather stations during 1967-2009. The influenced zone of each station was specified by the Thiessen method. It was attempted to make a new model of drought hazard using GIS. Three criteria for drought were studied and considered to define areas of vulnerability. Drought hazard criteria used in the present model included: maximum severity of drought in the period, trend of drought, and the maximum number of sequential arid years. Each of the vulnerability indicators were mapped and these as well as a final hazard map were classified into 5 hazard classes of drought: one, slight, moderate, severe and very severe. The final drought vulnerability map was prepared by overlaying three criteria maps in a GIS, and the final hazard classes were defined on the basis of hazard scores, which were determined according to the means of the main indicators. The final vulnerability map shows that severe hazard areas (43% of the country) which are observed in the west and eastern parts of country are much more widespread than areas under other hazard classes. Overall, approximately half of the country was determined to be under severe and very severe hazard classes for drought.