• Korea Journal of Hospital Management
• /
• v.7 no.4
• /
• pp.152-171
• /
• 2002

The research objective is segmenting outpatients for CRM(Customer Relationship Management) in medical service. Using modified RFM(Recently, Frequency, Monetary) method based on frequency and profitability in the hospital, the data were analyzed with the data mining technique. The result can be summarized as follows : The outpatients were semented into the four groups: 1) the loyal patient group, who have kept visiting until recently and give high profitability; 2) potential loyal patient group, who give lower profitability but high frequency of use, 3) potential withdrawer patient group, who have lower frequency of use but give high profitability and; 4) withdrawer patient group, who give low frequency of use and have not visited recently.

• The Journal of Internal Korean Medicine
• /
• v.30 no.1
• /
• pp.228-232
• /
• 2009

Objective : To expend the oriental medicine-based strategies or therapeutics for anemia, including iron deficiency anemia. Methods : A 23 year-old man suffering from severe and chronic iron deficiency anemia was believed to have disorder of iron absorption. He had neither specific medical cause nor positive response to western treatments. Blood and biochemical parameters such as levels of hemoglobin, ferritin, transferrin and serum iron were serially chased during treatments. Result : Bojungicki-tang was given to the patient based on diagnosis as a deficiency of spleen qi. The hemoglobin level was normalized along with administration of Bojungicki-tang. Also, the distortions of biochemical indicators (ferritin, transferrin and serum iron) reached a normal range within three months. Conclusion : Bojungicki-tang could be a curing remedy for iron deficiency anemia caused by problems in iron absorption if symptom-differentiation has deficiency of spleen qi.

• Journal of Information Technology Services
• /
• v.6 no.1
• /
• pp.1-15
• /
• 2007

An objective and valid knowledge activity indicator (KAI) is essential for encouraging knowledge activity in public institution. However, knowledge activity of public institution is inherently different from one of private corporation and, therefore, new method to find aggregated knowledge mileage considering public organizational culture and structure is to be developed. Therefore, this paper shows how to develop KAI of public institution based on three steps. First, knowledge activities were categorized as knowledge creation, knowledge sharing, and knowledge value increasing. Several knowledge indicators and hierarchical knowledge structure were developed for each knowledge categories. Second, personal knowledge mileage was calculated using AHP method considering whole organization's opinion. Finally, these approaches to find KAI were applied to "P" public institution as case studies. The results shows that KAI developed in this paper was very effective in grouping knowledge workers based on knowledge activities.

• Journal of Information Processing Systems
• /
• v.14 no.6
• /
• pp.1405-1419
• /
• 2018

An image fusion method is proposed on the basis of depth model segmentation to overcome the shortcomings of noise interference and artifacts caused by infrared and visible image fusion. Firstly, the deep Boltzmann machine is used to perform the priori learning of infrared and visible target and background contour, and the depth segmentation model of the contour is constructed. The Split Bregman iterative algorithm is employed to gain the optimal energy segmentation of infrared and visible image contours. Then, the nonsubsampled contourlet transform (NSCT) transform is taken to decompose the source image, and the corresponding rules are used to integrate the coefficients in the light of the segmented background contour. Finally, the NSCT inverse transform is used to reconstruct the fused image. The simulation results of MATLAB indicates that the proposed algorithm can obtain the fusion result of both target and background contours effectively, with a high contrast and noise suppression in subjective evaluation as well as great merits in objective quantitative indicators.

• Biomolecules & Therapeutics
• /
• v.32 no.2
• /
• pp.183-191
• /
• 2024

The Unfolded Protein Response (UPR) serves as a critical cellular mechanism dedicated to maintaining protein homeostasis, primarily within the endoplasmic reticulum (ER). This pathway diligently responds to a variety of intracellular indicators of ER stress with the objective of reinstating balance by diminishing the accumulation of unfolded proteins, amplifying the ER's folding capacity, and eliminating slow-folding proteins. Prolonged ER stress and UPR irregularities have been linked to a range of neuropsychiatric disorders, including major depressive disorder, bipolar disorder, and schizophrenia. This review offers a comprehensive overview of the UPR pathway, delineating its activation mechanisms and its role in the pathophysiology of neuropsychiatric disorders. It highlights the intricate interplay within the UPR and its profound influence on brain function, synaptic perturbations, and neural developmental processes. Additionally, it explores evolving therapeutic strategies targeting the UPR within the context of these disorders, underscoring the necessity for precision and further research to effective treatments. The research findings presented in this work underscore the promising potential of UPR-focused therapeutic approaches to address the complex landscape of neuropsychiatric disorders, giving rise to optimism for improving outcomes for individuals facing these complex conditions.

• Journal of the Korea Convergence Society
• /
• v.10 no.1
• /
• pp.187-195
• /
• 2019

There is a growing emphasis on objective and quantified performance measurement methodologies for the interactions that occur within modern companies. This is due to the importance of establishing and practicing future-oriented strategies by estimating the present value of the company and the current energy status through objective evaluation of the company. Therefore, the selection of KPI as a performance index using BSC (Balance Scorecard), which is a recent objective performance measurement methodology, has become very important. Although many studies on existing KPIs have been made in various industries, KPI studies on SI companies have been insufficient. This study focuses on finding KPIs applicable to SI companies. The study on the KPI design system according to general strategy of SI companies and the development of methodology and evaluation index according to index development for each group were carried out and the weighting methodology according to each evaluation index was presented.

• Journal of Korean society of Dental Hygiene
• /
• v.19 no.1
• /
• pp.65-78
• /
• 2019

Objectives: This study was conducted to characterize the impact of cognitive function and oral health status on mastication in senior citizens, ${\geq}65$ years of age, using senior centers in the city of Wonju, South Korea. Methods: A cross-sectional study consisting of a simple oral examination and survey questionnaires was performed in 154 individuals. General characteristics, subjective masticatory function, objective masticatory function, cognitive function, and oral health status were collected as variables. Correlation and multiple linear regression analyses were conducted. A p-value of <0.05 was considered to be statistically significant. Results: The subjective masticatory function was scored using the 5-point Likert scale. When subjective masticatory function was analyzed in groups according to cognitive function, the mean subjective masticatory function scores were 4.31, 4.09, and 3.29 in the normal group (cognitive score of ${\geq}16$), suspected dementia group (cognitive score of 1215), and mild dementia group (cognitive score of ${\leq}11$), respectively. Thus, subjective masticatory function decreased along with decreasing cognitive function. When cognitive function, subjective masticatory function, and objective masticatory function were compared with indicators of oral health status (number of functional teeth, oral dryness), subjective masticatory function exhibited a significant positive correlation with objective masticatory function (r=0.635, p<0.01), cognitive function (r=0.292, p<0.01), and total number of functional teeth, including prosthetic appliances (dentures) (r=0.305, p<0.01). According to the regression analysis, age, sex, number of functional teeth, and cognitive function affected subjective masticatory function. Conclusions: The results of this study revealed that age, sex, number of functional teeth, and cognitive function affected subjective masticatory function, whereas oral dryness did not. Therefore, dental professionals must consider subjective masticatory function when providing oral care in senior patients with low cognitive function.

• Animal Bioscience
• /
• v.35 no.1
• /
• pp.147-152
• /
• 2022

Objective: This study was conducted to obtain an objective index that can be quantified and used for establishing an animal welfare certification standard in Korea. For this purpose rumen pH, ruminating time, milk yield, milk quality, and blood components of cows reared in farms feeding high forage level (90%) and farms feeding low forage level (40%) were compared. Methods: Data on rumen pH, rumination time, milk yield, milk fat ratio, milk protein ratio, and blood metabolism were collected from 12 heads from a welfare farm (forage rate 88.5%) and 13 heads from a conventional farm (forage rate 34.5%) for three days in October 2019. Results: The rumination time was longer in cattle on the welfare farm than on the conventional farm (p<0.01), but ruminal pH fluctuation was greater in the cattle on conventional farm than the welfare farm (p<0.01). Conventional farms with a high ratio of concentrated feed were higher in average daily milk yield than welfare farms, but milk fat and milk production efficiency (milk fat and milk protein corrected milk/total digestible nutrients) was higher in cattle on welfare farms. Blood test results showed a normal range for both farm types, but concentrations of total cholesterol and non-esterified fatty acid were significantly higher in cows from conventional farms with a high milk yield (p<0.01). Conclusion: The results of this study confirmed that cows on the animal welfare farm with a high percentage of grass feed had higher milk production efficiency with healthier rumen pH and blood metabolism parameters compared to those on the conventional farm.

• Journal of Korean Society of Water and Wastewater
• /
• v.21 no.4
• /
• pp.453-465
• /
• 2007

With rapid expansion of the water market and growth of water companies, the recent trends in international water industry show that standardization of service activities concerning management of water and wastewater system (ISO/TC 224, to be issued in the second half year of 2007) is expected to have a large influence on the global water market including liberalization of water service market. In the Draft International Standard(DIS) of ISO/TC224, Performance Indicators(PIs) are suggested to estimate the service activities relating to water and wastewater treatment facilities. PIs have been developed in many countries including some international organization(World Bank, IWA and etc.) for service benchmarking. To evaluate public service level and establish plans to improve service level of wastewater utilities, we developed PIs for 120 items and applied them to 10 sewage utilities in the consideration of their scales, circumstances and conditions. In this study, we verified the applicability of the developed performance indicators(PIs). So, we concluded that PIs developed for the purpose of this study can be a useful tool applicable to objective evaluation of the service level of sewage utilities. Using the evaluation tool of PIs developed, it can also be used as a benchmarking tool in this industry as well as for enhancing the efficiency of operation and management of the sewage system. It will also contribute to the water resource management through determination of investment priorities based on the evaluation results and to raising international competitiveness of the domestic sewage utilities to meet the future opening of the water market.

• Spatial Information Research
• /
• v.8 no.2
• /
• pp.233-241
• /
• 2000

The objective of this study were to develop landscape scale ecosystem assessment model, and apply the model for the assessment of the state and change of ecosystem of the study area, Yongin, Korea. Since natural ecosystem of the site has been deteriorated significantly during recent extensive residential development, it is essential to correctly assess ecosystem of the study site. Traditional ecosystem assessment mainly utilizing intensive field survey requires high cost, but the outcome rarely represents spatial pattern of the regional ecosystems. Ecosystem assesment of landscape scale based on landscape ecology can resolve most of the shortfalls of the traditional approach. The research method can be summarized as follows. First, extensive literature review on such topics as spatial pattern of ecosystem, ecosystem assessment of landscape scale, ecological analysis was carried out. Second, a model for the ecosystem assessment of landscape scale emphasizing spatial pattern of ecosystem was developed. This model evaluates three indicators; ecological integrity and biological diversity, watershed integrity, and landscape resilience of 11 watersheds in the study area. Finally, ecological assessment utilizing two sets of indicators, enhancement of and disturbance of ecosystem stability, was carried out. This assessment method is based on Environmental Monitoring and Assessment Program´s Landscape component(EMAP-L) of EPA(1994). The results of this study are as follows. First, the ecosystem assessment of landscape scale of the study area of Yongin, Korea, showed that escosystems of Tanchun01 and Chungmichun01 watersheds had the worst state in the study site in 1991. On the other hand, the ecosystems of Jinwechun01, Kyunganchun02, and Bokhachun01 watersheds had the most stable ecosystem in 1991. Second, ecosystems of Tanchun01, Shingal reservoir, and Kyunganchun01 watersheds were evaluated to be the worst state in the study site in 1996. And, ecosystems of Jinwechun01 and Gosam reservoir watersheds had the most stable ecosystem. Third, ecosystem of Tanchun01 watershed which incudes Suji residential development project site changed the most drastically between 1991 and 1996. The ecosystem of the watershed the most drastically deteriorated due to it´s proximity to Seoul and Bundang new town.