• Women's Health Nursing
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• v.16 no.4
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• pp.399-408
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• 2010

Purpose: The purpose of this study was to investigate differences of subjective, objective knowledge and educational need about contraceptives according to sex in college students. Methods: Data were collected by a self-administered questionnaire from 84 male and 111 female college students on May, 2008. PASW 18.0 program was used for data analysis. Results: There were significant differences in age, major, grade, place of residence, and experience of sexual intercourse between male and female college students. There was a significant difference in objective knowledge about contraceptives between the two groups, but no significant difference in subjective knowledge. The positive correlation was shown between subjective and objective knowledge about contraceptives. Even when demographic variables such as age, major, grade, place of residence, and experience of sexual intercourse were controlled, sex was a significant influencing factor on subjective and objective knowledge about contraceptives. Educational need about emergency contraceptive pills was significantly different and ranking of educational need about contraceptives was also different between the two groups. Conclusion: These results suggest that different education programs according to sex are needed to maximize the effect of contraceptive education and sexual characteristics are considered to give an education to college students.

• Journal of the Korean Society of Clothing and Textiles
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• v.30 no.5 s.153
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• pp.818-828
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• 2006

The purpose of this study was to clarify differences in the product attribute evaluation in relation to the objective knowledge, subjective knowledge and involvement of apparel. The measurement instruments were developed by researcher on the basis of previous studies in the same field. The subjects of this study were female adults who lived in Seoul, Kyunggi or Incheon areas and quota sampling using age and residential areas was employed. The data were obtained from 603 questionnaires. Data were statistically analyzed using SPSS 10 and LISREL 7.0. Major statistical methods were factor analysis, Cronbach's a coefficient, multiple regression analysis, and structural equation model analysis. The results were as follows: 1. Involvement was related to the consumer knowledge and the knowledge influenced evaluation of intrinsic attributes, social attributes, and economic attributes. 2. The dimensions of objective knowledge significantly influenced intrinsic attributes and economic attributes. The dimensions of subjective knowledge significantly influenced intrinsic attributes, social attributes and economic attributes. 3. Apparel involvement significantly influenced intrinsic attributes, social attributes and economic attributes. Consumers who have higher interest in apparel product but not in trends considered intrinsic attributes more importantly, whereas consumers who care trends considered social attribute more.

• Journal of People, Plants, and Environment
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• v.24 no.2
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• pp.179-194
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• 2021

Background and objective: Plant-based biofilter system has become a promising candidate for improving indoor air quality due to its eco-friendly and sustainable nature. However, it remains controversial whether indoor air purification using a biofilter is effective. Methods: This study used the one-group pre- and post-test design to analyze the effects of the operation of the plant-based biofilter system on indoor air quality, students' perception of indoor air quality, health effects, and subjective and objective attentiveness. Results: Results of this study show that the application of the plant-based biofilter system changed the air environment in the classroom. The operation of the plant-based biofilter system significantly decreased PM_2.5 and PM₁₀ and slightly increased temperature and humidity. Satisfaction with air quality and subjective attentiveness were significantly improved but objective attentiveness and health effects were not improved. Conclusion: Further studies need to be conducted for improving indoor air quality of schools and evaluating the health effects and attention of occupants to present the objective performance of the plant-based biofilter system.

• The Journal of Korean Medicine
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• v.28 no.1 s.69
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• pp.137-147
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• 2007

Objective : The objective of this study was to investigate the antioxidative effects of Carthami Flos extract. Methods : Total antioxidant status was examined by total antioxidant capacity(TAC) and total antioxidant response(TAR) against potent free radical reactions. The effect of Carthami Flos extract was examined far details of total phenolic content concentration at which 1,1-dipheny1-2-picrylhydrazyl(DPPH) radical scavenging activity was inhibited, the inhibitory effect on lipid peroxidation, and the effect on reactive oxygen species(ROS) generation. Results : TAC of Carthami Flos extract at the concentration of 5 mg/ml was 1.84 mM Trolox equivalent. 2. TAR of Carthami Flos extract, on the other hand, couldn't be determined due to interference from unidentified compounds. 3. Total phenolic content of Carthami Flos extract at the concentration of 5 mg/ml was 2.01 mM gallic acid equivalent. 4. Concentration of Carthami Flos extract at which DPPH radical scavenging activity was inhibited by 50% was 6.43 mg/ml as compared to 100% by Pyrogallol solution as a reference. 5. The inhibitory effect of the extract on lipid peroxidation was examined using rat liver mitochondria induced by FeS04/ascorbic acid. Carthami Flos extract at the concentration of 10 ms/ml slightly but significantly decreased TBARS concentration. The extract continued to prevent lipid peroxidation in a dose-dependent manner. 6. The effect of Carthami Flos extract on reactive oxygen species(ROS) generation was examined using a cell-free system induced by hydrogen peroxide/FeS04. Addition of 1 mg/ml of Carthami Flos extract significantly reduced dichlorofluorescein(DCF) fluorescence. Carthami Flos extract caused concentration-dependent attenuation of the increase in DCF fluorescence, indicating that the ektract significantly prevented ROS generation in vitro. Conclusion: : Antioxidant efffcts of Carffami ffor extract seem to be due, at least in part, to the prevention offree radical-induced oxidation, fellowed by inhibition of lipid peroxidation.

• The KIPS Transactions:PartB
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• v.11B no.7 s.96
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• pp.841-848
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• 2004

Evolutionary a1gorithms are well-suited for multi-objective optimization problems involving several, often conflicting objectives. Pareto-based evolutionary algorithms, in particular, have shown better performance than other multi-objective evolutionary algorithms in comparison. However, generalized evolutionary multi-objective optimization algorithms have a weak point, in which the distribution of solutions are not uni-formly distributed onto Pareto optimal front. In this paper, we propose an evolutionary a1gorithm for multi-objective optimization which uses seed individuals in order to overcome weakness of algorithms Published. Seed individual means a solution which is not located in the crowded region on Pareto front. And the idea of our algorithm uses seed individuals for reproducing individuals for next generation. Thus, proposed a1go-rithm takes advantage of local searching effect because new individuals are produced near the seed individual with high probability, and is able to produce comparatively uniform distributed pareto optimal solutions. Simulation results on five testbed problems show that the proposed algo-rithm could produce uniform distributed solutions onto pareto optimal front, and is able to show better convergence compared to NSGA-II on all testbed problems except multi-modal problem.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.5
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• pp.199-209
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• 2021

The purpose of this study was to explore objective indicators(outcomes) which are used to evaluate clinical efficacy and figure out the mechanisms of herbal medicine, acupuncture and moxibustion treatment for Irritable bowel syndrome(IBS). We searched randomized controlled trials(RCTs) that mediated with herbal medicine, acupuncture and moxibustion treatment for IBS and used objective indicators for outcome from November 1, 2020 to December 31, 2020. The RCTs that were published in Korean, English and Chinese were included in this study. The selected literatures were analyzed about methods of result measurement and assessed by Cochrane's risk of bias(RoB). Total 18 RCTs were included in this study. There were lots of objective indicators for result measurement; the concentration of hormones in blood and neurotransmitters, the sensitivity of rectum, the functional assessment of central nerve and autonomic nerve system, the change of intestinal flora, the concentration of serum cytokines. Various objective indicators can be used to evaluate the clinical efficacy of with herbal medicine, acupuncture and moxibustion treatment for IBS, but due to the limitations of the quality of the included studies, systematic review and meta-analysis will be needed.

• Journal of Korean Academy of Nursing
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• v.34 no.6
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• pp.1004-1013
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• 2004

Purpose: The purpose of this paper was to describe the characteristics of smoking prevention programs in Korea, to estimate overall effect size of Korean smoking prevention programs, and to investigate effect size variations by program modality and instruction method. Method: Meta-analysis was performed on2l programs in 20 studies. Result: The estimation of overall effect size for knowledge and attitude was not possible because effect sizes were not homogeneous in this meta-analysis. However, effect sizes of studies that were socially influential programs or active/interactive methods were larger than information-oriented programs or passive/non-interactive methods in the pictures. The effects for behavioral outcomes were generally not as positive and not statistically significant. Q statistics showed that variations among effect sizes within program modality and instruction method classifications were heterogeneous. Conclusion: The results from this meta-analysis support the continued use of socially influential programs and active/interactive methods for smoking prevention programs. Because behavioral effect might be the fundamental objective of smoking prevention programs, the present results indicate that smoking prevention programs should consider adopting more effective programs.

• Herbal Formula Science
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• v.27 no.4
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• pp.245-255
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• 2019

Objective : Herbal processing is one of the traditional techniques used in Korean medicine to increase the effectiveness of herbs or reduce their toxicity. In this study, Gardeniae Fructus processed with ginger juice and alcohol was prepared to evaluate the anti-inflammatory effect on lipopolysaccharide (LPS)-induced macrophages. Methods : The processing of Gardeniae Fructus was performed by adding 40 % ginger juice or 10% alcohol to the total weight of Gardeniae Fructus and then roasting at 150℃ for 5 minutes. Cell viability was determined by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. To detect nitric oxide (NO) production, culture media were mixed with Griess reagent and measured the absorbance at 540 nm. Prostaglandin E₂ (PGE₂) and pro-inflammatory cytokines were detected by enzyme-linked immunosorbent assay (ELISA). Western blot was applied to monitor protein expression levels. Results : LPS-induced NO, PGE₂ and inflammatory cytokines were decreased by the treatment of normal or processed Gardeniae Fructus ethanol extracts (GFE). Compared to normal GFE, the processed GFE showed a stronger inhibitory effect on the production of NO and PGE₂. These inhibitory effect of GFE was due to the suppression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) mediated from the inhibition of nuclear factor kappa B (NF-κB). Furthermore, processed GFE showed more suppressive effects on the expression of iNOS, COX-2 and IκBα proteins than normal GFE. Conclusion : From these results, it was concluded that GFE had an improved anti-inflammatory effect compared to normal GFE. These results provide an objective evidences for the use of herbal processing in Korean medicine.

• The Journal of Korean Medicine
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• v.28 no.1 s.69
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• pp.148-158
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• 2007

Objective : The objective of this study was to investigate the antioxidant effects of Mori Folium extract. Methods Total antioxidant status was examined by total antioxidant capacity(TAC) and total antioxidant response(TAR) against potent free radical reactions. The effect of Mori Folium extract was examined by measuring total phenolic content, concentration at which 1,1-dipheny1-2-picrylhydrazyl(DPPH) radical scavenging activity was inhibited, inhibitory effect on lipid peroxidation, and the effect on reactive oxygen species(ROS) generation. Results : 1. TAC and TAR of Mori Folium extract at the concentration of 5 mg/ml were 1.61 and 1.24 mM Trolox equivalents, respectively. 2. Total phenolic content of Mori Folium extract at the concentration of 5 mg/Ml was 1.70 mM gallic acid equivalent. 3. Concentration of Mori Folium extract at which DPPH radical scavenging activity was inhibited by 50% was 2.29 m9/m4 as compared to 100% by Pyrogallol solution as a reference. 4. The inhibitory effect of the extract on lipid peroxidation was examined using rat liver mitochondria induced by FeSO$_4$/ascorbic acid. Mori Folium extract at the concentration of 10 mg/ml significantly decreased thiobarbituric acid reactive substances(TBARS) concentration. The extract prevented lipid peroxidation in a dose-dependent 5. The effect of Mori Folium extract on reactive oxygen species(ROS) generation was examined using a celt-free system induced by hydrogen peroxide FeSO$_4$. Addition of 1 mg/ml of Mori Folium extract significantly reduced dichlorofluorescein(DCf) fluorescence. The extract caused concentration-dependent attenuation of the increase in DCF fluorescence, indicating that the extract significantly prevented ROS generation in vitro. Conclusion ; The antioxidant effects of Mori Folium extract seem to be due, at least in part, to the prevention offree radical-induced oxidation, fllowed by inhibition of lipid peroxidation.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.3
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• pp.334-340
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• 2019

Objective: The objective of this study was to investigate the genetic components of daily milk yield and to re-rank bulls in South Korea by estimated breeding value (EBV) under heat stress using the temperature-humidity index (THI). Methods: This study was conducted using 125,312 monthly test-day records, collected from January 2000 to February 2017 for 19,889 Holstein cows from 647 farms in South Korea. Milk production data were collected from two agencies, the Dairy Cattle Genetic Improvement Center and the Korea Animal Improvement Association, and meteorological data were obtained from 41 regional weather stations using the Automated Surface Observing System (ASOS) installed throughout South Korea. A random regression model using the THI was applied to estimate genetic parameters of heat tolerance based on the test-day records. The model included herd-year-season, calving age, and days-in-milk as fixed effects, as well as heat tolerance as an additive genetic effect, permanent environmental effect, and direct additive and permanent environmental effect. Results: Below the THI threshold (${\leq}72$; no heat stress), the variance in heat tolerance was zero. However, the heat tolerance variance began to increase as THI exceeded the threshold. The covariance between the genetic additive effect and the heat tolerance effect was -0.33. Heritability estimates of milk yield ranged from 0.111 to 0.176 (average: 0.128). Heritability decreased slightly as THI increased, and began to increase at a THI of 79. The predicted bull EBV ranking varied with THI. Conclusion: We conclude that genetic evaluation using the THI function could be useful for selecting bulls for heat tolerance in South Korea.