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Review on the Objective Effect and Mechanism Studies of Herbal Medicine, Acupuncture and Moxibustion Treatment for Irritable Bowel Syndrome Patients

과민성 대장증후군 환자를 대상으로 수행된 한약 및 침구치료의 객관적 효과와 기전 연구에 대한 문헌고찰

  • Noh, Hyun Deok (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • Kim, Min Jeong (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • Cho, Im Hak (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • Kim, So Yeon (Department of Korean Medicine, School of Korean Medicine, Pusan National University)
  • 노현덕 (부산대학교 한의학전문대학원 한의학과) ;
  • 김민정 (부산대학교 한의학전문대학원 한의학과) ;
  • 조임학 (부산대학교 한의학전문대학원 한의학과) ;
  • 김소연 (부산대학교 한의학전문대학원 한의학과)
  • Received : 2021.07.19
  • Accepted : 2021.10.22
  • Published : 2021.10.25

Abstract

The purpose of this study was to explore objective indicators(outcomes) which are used to evaluate clinical efficacy and figure out the mechanisms of herbal medicine, acupuncture and moxibustion treatment for Irritable bowel syndrome(IBS). We searched randomized controlled trials(RCTs) that mediated with herbal medicine, acupuncture and moxibustion treatment for IBS and used objective indicators for outcome from November 1, 2020 to December 31, 2020. The RCTs that were published in Korean, English and Chinese were included in this study. The selected literatures were analyzed about methods of result measurement and assessed by Cochrane's risk of bias(RoB). Total 18 RCTs were included in this study. There were lots of objective indicators for result measurement; the concentration of hormones in blood and neurotransmitters, the sensitivity of rectum, the functional assessment of central nerve and autonomic nerve system, the change of intestinal flora, the concentration of serum cytokines. Various objective indicators can be used to evaluate the clinical efficacy of with herbal medicine, acupuncture and moxibustion treatment for IBS, but due to the limitations of the quality of the included studies, systematic review and meta-analysis will be needed.

Keywords

Acknowledgement

이 과제는 부산대학교 기본연구지원사업(2년)에 의하여 연구되었음.

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