• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.19 no.2
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• pp.130-138
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• 2016

Purpose: This study was conducted to analyze the change in the obesity index in girls receiving a gonadotropin-releasing hormone agonist (GnRHa), based on treatment duration, and to aid in nutritional counseling by investigating dietary habits and lifestyle. Methods: Anthropometric examinations were conducted on 62 girls treated with GnRHa from January 2010 through July 2014. Parents were asked to fill out questionnaires on patient dietary habits and lifestyle. Results: The group taking GnRHa for over 1 year had a higher rate of obesity increase than the group taking GnRHa for less than 1 year, but they had common habits related to obesity, which should be corrected. In addition, 69.2% of the normal weight group taking GnRHa for over 1 year gained weight, and needed more intensive programs, which include physical exercise and nutritional education. Although girls with precocious puberty showed a decrease in the intake of high-calorie foods with nutritional intervention regardless of treatment duration, they still had problems that needed improvement, such as shorter meals and lack of exercise. Conclusion: Girls with precocious puberty and their parents should emphasize maintenance of proper body weight, especially when treatment for over 1 year is anticipated. Consistent education in nutrition, ways to increase intensity and duration of physical activity, and the need to slow down mealtimes are important in managing obesity; doctors need to perform regular checkups and provide nutritional counseling.

• Journal of Korean Medicine for Obesity Research
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• v.6 no.2
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• pp.95-104
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• 2006

Objectives : This study was performed to assess the effect onf abdominal obesity treatment on changes in abdominal subcutaneous and visceral fat. Methods : The study was conducted on 61 abdominally obese patients (13 men and 48 women). Measures of body weight, waist circumference, abdominal subcutaneous and visceral fat area by CT scan, and V/S ratio (Viscero-subcutaneous fat ratio) were acquired before and after Kirindiet therapy. Paired t-test and Wilcoxon signed rank tests were used to est the effects of teatment. Results : Following a mean of 68 days of treatment, waist circumference (-15%), abdominal total fat (-40%), subcutaneous fat (-37.9%), visceral fat (-47.8%) and V/S ratio (-11.1%) were significantly reduced (p<0.05). The change in V/S ratio in female patients was not statistically significant (p=0.491) whereas the change in the V/S ratio in male patients was significant indicating a greater loss of visceral fat (p=0.017). Please check that my changes reflect what the study found Conclusions : The reduction in visceral fat was greater than for subcutaneous fat in male patients but not for female patients.

• Journal of Korean Medicine for Obesity Research
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• v.24 no.1
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• pp.102-110
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• 2024

This study reports the clinical effects of Korean medicine treatments, herbal medicine, modified fasting, and space spinal conduction exercise and manipulation (SSCEM) on adolescent obesity patient. A 16-year-old male with a body mass index (BMI) 35.5 kg/m² was diagnosed with class III obesity. We prescribed herbal medicine and modified fasting alternately three times over a period of five months. Additionally, Korean medicine treatments and SSCEM were performed during the treatment period. After treatment, there was a decrease in body weight by 19.86%, from 115.8 kg to 92.8 kg, BMI from 35.5 kg/m² to 28.6 kg/m², and body fat mass from 38.1 kg to 17.0 kg. The results of this study showed that Korean medicine treatments, herbal medicine, modified fasting, and SSCEM could be useful in influencing changes in body composition among obese adolescents.

• Journal of Korean Medicine for Obesity Research
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• v.21 no.1
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• pp.22-31
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• 2021

Objectives: We conducted a retrospective chart review to investigate the effects of Korean Medicine (KM) treatment on weight loss in patients with morbid obesity (body mass index [BMI]≥30 kg/m²) and to compare the effects of KM counseling and non-counseling on weight loss. Methods: We performed a retrospective chart review of patients with morbid obesity who received KM treatment for at least 1 month. We evaluated the effects of KM treatment on body weight, BMI, body fat, fat mass, EuroQol-5D, and the Korean version of the obesity-related quality of life scale (KOQOL). We also assessed the liver and kidney functions, and adverse events. We performed a comparative analysis between the counseling and non-counseling groups. Results: A total of 37 patients who underwent 4 weeks of KM treatment involving Wolbi-tang, electroacupuncture, and KM counseling were included in this study. Twenty-one patients were assigned to the counseling group and sixteen patients to the non-counseling group. There was a significant decrease in weight, BMI, fat mass, and KOQOL (P<0.05) with improvements in total cholesterol, low-density lipoprotein, and triglycerides. The counseling group had a greater reduction in body weight, BMI, body fat, and fat mass compared to the non-counseling group, although it was not significant. In the BMI below 35 (n=25), the reduction ratio of body weight, body fat mass, and body fat was higher in the counseling group than in the non-counseling group; additionally, body fat decreased significantly in counseling group (P<0.05). No severe adverse effects were observed. Conclusion: KM treatment could be effective for weight loss, especially in patients with morbid obesity, KM counseling could also be a good tool for weight loss, typically in patients with BMI<35 kg/m².

• Journal of The Korean Society of Clinical Toxicology
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• v.10 no.2
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• pp.111-117
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• 2012

Purpose: In Korea, few studies have examined the acute toxicity of anti-obesity drugs. The purpose of this study is to analyze the general characteristics and clinical aspect of acute anti-obesity drug intoxication. Methods: We retrospectively investigated patients admitted to the emergency department after anti-obesity drug intoxication between March, 2004 and February, 2012. The medical records of these patients were reviewed for demographic data, toxicologic history, time elapsed to presentation, clinical symptoms and signs, treatment, and outcome. Results: There were a total of 18 anti-obesity intoxication cases during the study period; of 16 which were included in our study. The purchasing route of the anti-obesity drug was mainly through a doctor's prescription (68.8%), however, some were obtained through the internet and the pharmacies. The mean time to The most commonly ingested antiobesity drug was sibutramine (31.3%) and many of the cases (62.5%) were multi-drug ingestions. The most common clinical manifestations were gastrointestinal symptoms (94%), but, CNS symptoms (75%) and cardiovascular symptoms (75%) were almost equally present. 13 patients (81%) were discharged after clearance of toxic symptoms and signs with a mean observational period of 7.0 hours. 3 patients were admitted for observation and treatment; of which 1 patient died due to fatal complications. Conclusion: Most anti-obesity intoxications show mild toxicity and a nonfatal clinical course. However, the recent trend toward prescribing psychostimulant anti-obesity medication, which can be fatal after an acute overdose, calls physicians' attention to treating of anti-obesity intoxications.

• Journal of Korean Medicine for Obesity Research
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• v.7 no.2
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• pp.1-14
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• 2007

Objective The purpose of this study is to work on the direction of the study with regard to the sarcopenic obesity. Methods We searched articles relative to sarcopenic obesity in the KyungHee University Meta-analysis database. We classified articles according to type of study and subject clinical characteristics, assessment, medical complications and treatment. Results and Conclusion Data from this pilot study showed that sarcopenic obesity is associated with metabolic abnormality, cancer, increased frailty, physical disability and inflammatory markers. Therefore, clinical studies are needed to demonstrate the effectiveness and safety of management for sarcopenic obesity.

• Journal of Korean Medicine for Obesity Research
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• v.6 no.1
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• pp.45-50
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• 2006

Objectives : The purpose of this study is to analyze the seven passions in terms of physical vector, and to understand the point of actions and directions. The result of this study will help us understand the aspect that the seven passions result in obesity and contribute in finding effective treatments. Methods : The characters of each seven passions were identified according to ${\ulcorner}$Hwangjenaekyung-Huangdineijing${\lrcorner}$. Results and Conclusions : 1. Each of the seven passions differs individually in physical characters in terms of points of actions and directions. 2. As the vector points of each seven passion work closely to digestive metabolism, and if the directions of vector clash into normal physiology, huge effects on obesity can be brought about. 3. Obesity, as a pathological situation, can be approached by canceling out all the vector elements of the seven passions. Here, the vector elements are basically regarded as the sources of obesity. 4. Psychological models of obesity can be applied for prevention and treatment.

• Journal of Yeungnam Medical Science
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• v.41 no.3
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• pp.150-157
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• 2024

The prevalence of childhood and adolescent obesity has increased and exacerbated during the coronavirus disease 2019 pandemic, both in Korea and globally. Childhood and adolescent obesity poses significant risks for premature morbidity and mortality. The development of serious comorbidities depends not only on the duration of obesity but also on the age of onset. Obesity in children and adolescents affects almost all organ systems, including the endocrine, cardiovascular, gastrointestinal, reproductive, nervous, and immune systems. Obesity in children and adolescents affects growth, cognitive function, and psychosocial interactions during development, in addition to aggravating known adult comorbidities such as type 2 diabetes mellitus, hypertension, dyslipidemia, nonalcoholic fatty liver disease, obstructive sleep apnea, and cancer. Childhood and adolescent obesity are highly associated with increased cardiometabolic risk factors and prevalence of metabolic syndrome. The risk of cardiovascular and metabolic diseases in later life can be considerably decreased by even a small weight loss before the onset of puberty. Childhood and adolescent obesity is a disease that requires treatment and is associated with many comorbidities and disease burdens. Therefore, early detection and therapeutic intervention are crucial.

• Korean Journal of Psychosomatic Medicine
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• v.29 no.2
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• pp.86-94
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• 2021

Objectives : The risk of weight gain is high when using antipsychotic drugs, and the prevalence of obesity in people with mental illness is high. Obesity management in psychiatric patients is important because obesity causes various complications and lowers treatment adherence and quality of life. Methods : In this review, we summarized the management strategies for obesity that can occur when using antipsychotic drugs through a web search. Results : Evaluate obesity-related risk factors and related indicators from the beginning of treatment, and conduct regular monitoring. If an antipsychotic drug is used and obesity is induced, a change to a drug with a low metabolic risk may be attempted. Sufficient interventions are also needed on the need to manage obesity, a healthy diet, and exercises in patients and their families. If weight loss is not achieved and obesity-related complications are associated, the use of anti-obesity drugs may be considered. Pharmacological treatment approaches should be carefully considered. Conclusions : Non-pharmacological and pharmacological therapies can be applied to manage weight gain and obesity caused by the use of antipsychotic drugs. When using anti-obesity drugs, the characteristics of mental disorders, drug safety, and drug interactions should be considered.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.3
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• pp.197-204
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• 2009

Purpose: Obesity is the major risk factor of the heart disease and the metabolic disease. And many obese women have dysfunction of the endocrine system. There are many reports about oriental obesity treatment program. In clinics, the electroacupuncture with exercise is believed more effective. But the difference of weight loss as exercise and women was not studied. Methods: The subjects were 75 young women who visited Kangnam Kyunghee hospital for obesity management from March 2006 to July 2008. Six treatments had performed, the weight loss checked at every treatment. 52 women treated by oriental obesity treatment with exercise, 23 women treated therapy without exercise. As the exercise and the age, the weight loss was compared. Results: The weight loss of electroacupuncture with exercise was higher than that of electroacupuncture without exercise, but was not significant. The weight loss of perimenopausal women was significantly low. Conclusion: The comparison of electroacupuncture with exercise and electroacupuncture without exercise was not significantly different. The weight loss of the older women would be less than the weight loss of the younger.