Obesity is an epidemic disease characterized by an increased inflammatory state and chronic oxidative stress with high levels of pro-inflammatory cytokines and lipid peroxidation. Moreover, obesity alters cholesterol metabolism with increases in low-density lipoprotein (LDL) cholesterols and triglycerides and decreases in high-density lipoprotein (HDL) cholesterols. It has been shown that mulberry leaf and fruit ameliorated hyperglycemic and hyperlipidemic conditions in obese and diabetic subjects. We hypothesized that supplementation with mulberry leaf combined with mulberry fruit (MLFE) ameliorate cholesterol transfer proteins accompanied by reduction of oxidative stress in the high fat diet induced obesity. Mice were fed control diet (CON) or high fat diet (HF) for 9 weeks. After obesity was induced, the mice were administered either the HF or the HF with combination of equal amount of mulberry leaf and fruit extract (MLFE) at 500mg/kg/day by gavage for 12 weeks. MLFE treatment ameliorated HF induced oxidative stress demonstrated by 4-hydroxynonenal (4-HNE) and modulated the expression of 2 key proteins involved in cholesterol transfer such as scavenger receptor class B type 1 (SR-B1) and ATP-binding cassette transporter A1 (ABCA1) in the HF treated animals. This effect was mainly noted in liver tissue rather than in cutaneous tissue. Collectively, this study demonstrated that MLFE treatment has beneficial effects on the modulation of high fat diet-induced oxidative stress and on the regulation of cholesterol transporters. These results suggest that MLFE might be a beneficial substance for conventional therapies to treat obesity and its complications.
Objectives: Obesity is chronic condition which can severely influence health. People with a high percentage of body fat (%BF) have high prevalence of hypertension and hypercholesterolemia. Abdominal obesity (AO) seems to play a major role in the development of cardiovascular disease, diabetes and hyperlipidemia. This study investigated the %BF and AO of workers in the automobile manufacturing industry. Methods: The subjects were categorized by sex, age, job class, drinking history and smoking history. %BF and AO were measured by using bioelectrical impedance analysis (Jawon Medical, Seoul, Korea). We analyzed the relationship between age, sex, job class, drinking history, smoking history and %BF and WHR into frequencies, $X^2$-test using the SPSS Ver. 12.0. Results: Regarding the relationship between sex and %BF, AO, there was statistically significant difference as men had a significant higher level of %BF and AO than women. There was a positive correlation between age and both %BF and AO. Workers in their 40s especially ran level of AO up. In job class, office workers were apt to have a higherlevel of %BF and AO than production line workers. %BF and AO of the non-drinker group showed a lower level than the drinker group. On the other hand, the ex-smoker group had higher levels of %BF and AO than the non-smoker or current-smoker groups. Conclusions: The above results showed that men, the advanced in years, office workers, drinkers and ex-smokers had high levels of %BF and AO.
Najafi, Farid;Pasdar, Yahya;Hamzeh, Behrooz;Rezaei, Satar;Nazar, Mehdi Moradi;Soofi, Moslem
Journal of Preventive Medicine and Public Health
/
v.51
no.6
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pp.289-297
/
2018
Objectives: Obesity is a considerable and growing public health concern worldwide. The present study aimed to quantify socioeconomic inequalities in adult obesity in western Iran. Methods: A total of 10 086 participants, aged 35-65 years, from the Ravansar Non-communicable Disease Cohort Study (2014-2016) were included in the study to examine socioeconomic inequalities in obesity. We defined obesity as a body mass index ${\geq}30kg/m^2$. The concentration index and concentration curve were used to illustrate and measure wealth-related inequality in obesity. Additionally, we decomposed the concentration index to identify factors that explained wealth-related inequality in obesity. Results: Overall, the prevalence of obesity in the total sample was 26.7%. The concentration index of obesity was 0.04; indicating that obesity was more concentrated among the rich (p<0.001). Decomposition analysis indicated that wealth, place of residence, and marital status were the main contributors to the observed inequality in obesity. Conclusions: Socioeconomic-related inequalities in obesity among adults warrant more attention. Policies should be designed to reduce both the prevalence of obesity and inequalities in obesity by focusing on those with higher socioeconomic status, urban residents, and married individuals.
Kim, Yang-Hyun;Han, Kyungdo;Son, Jang-Won;Lee, Seong-Su;Oh, Sang Woo;Kwon, Hyuk-Sang;Shin, Soon-Ae;Kim, Yeon-Yong;Lee, Won-Young;Yoo, Soon Jib;Taskforce Team of the Obesity Fact Sheet of the Korean Society for the Study of Obesity
Journal of Obesity & Metabolic Syndrome
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v.26
no.1
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pp.23-27
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2017
Background: In Korea, the prevalence of obesity has steadily increased, and the socioeconomic burden of obesity has increased along with it. In 2015, the National Health Insurance Service (NHIS) signed a memorandum of understanding with the Korean Society for the Study of Obesity (KSSO), providing limited open access to its databases so that the status of obesity and obesity management could be investigated. Methods: Using NHIS databases, we analyzed nationwide population-based studies for obesity using the definition of obesity (body mass index ${\geq}25kg/m^2$) in subjects over the age of 20. Age and sex standardization were used for all data. Results: The KSSO released the 'Obesity Fact Sheet 2016' using the 2006-2015 NHIS Health Checkup database. The prevalence of obesity steadily increased from 28.7% in 2006 to 32.4% in 2015, and the prevalence of abdominal obesity also steadily increased from 18.4% in 2009 to 20.8% in 2015. The prevalence of class II obesity steadily increased from 2006 to 2015, such that the total prevalence was 4.8% in 2015 (5.6% in men and 4.0% in women). The highest prevalence of obesity was found in Jeju Island, while the lowest prevalence was found in Daegu City. The highest prevalence of abdominal obesity was also found in Jeju Island, while the lowest prevalence was found in Gwangju City. Conclusion: Based on the Obesity Fact Sheet 2016, a strategy for reducing the prevalence of obesity is needed, especially in Korean men.
Journal of Korean Academy of Fundamentals of Nursing
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v.15
no.4
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pp.475-484
/
2008
Purpose: The purpose of this study was to identify effects of an obesity control program including rhythmical dance exercise, on body composition, knowledge about obesity, life habits and self-esteem among obese elementary school children. This program included obesity related health education and counseling based on behavior modification once a week, 1 hour-rhythmical dance class once a week and 40-minute jump rope classes twice a week for 8 weeks. Method: There were 29 students with obesity in the experimental and 28 in the control group. Participated was voluntary. The data were collected from April 16 to July 6 2007. $x^2$-test, Fisher's exact test, paired t-test and t-test were used to analyze the data. Results: Students in the experimental group showed significantly lower fat mass (t=-2.16, p=.036) and percent body fat (t=-2.93, p=.005) and significantly higher muscle mass (t=2.05, p=.045) and lean body mass (t=2.71, p=.009) than those in the control group. Knowledge of obesity increased significantly and eating habits changed significantly. But difference in exercise habits and self-esteem were not significant. Conclusion: This study provides evidence that an 8 week-obesity control program including rhythmical dance exercise is effective in decreasing body fat, increasing muscle mass and increasing knowledge of obesity in children who are obese.
To study the factors related to childhood obesity, 75 subjects were selected as an obese group and 75 subjects were selected as a control group according to their obesity index and BMI among the 583 children of 5th and 6th grade in elementary school in Seoul. For each subject, skinfold thickness was measured, information on the characteristics of family, nutrient intake and activity time of the subjects were obtained by questionnarie. The results were summarized as following: 1) Parents' obesity indices of obese group were significantly higher than those of control group(Father's Obesity Index : P<0.01, Mother's Obesity Index : P<0.05). 2) Questions about eating rate and behavior showed that subjects in obese group were significantly faster in their eating rate(p<0.05) and always more eager to eat food(p<0.001) compared to control group. 3) Dietary intake data showed that average daily intake of all the nutrients exceeded Korean recommended dietary allowances for the age group. In female children, fat intakes of obese group were significantly higher than control group(P<0.05). There was no such significant difference in male subjects. 4) Activity time record of subjects reveal that there was a trend for males to spend more time in moderate and high activity and less time in light activity compared to females. Subjects in obese group spent significantly more time for light activity(P<0.001) and significantly less time for moderate activity (P<0.001) compared to subjects in control group. The difference of activity was more pronounced in male subjects. 5) Correlation matrix of the variables showed that obesity index, BMI, and skinfold thickness of the subjects were highly correlated with each other. These indices were positively correlated to parent's obesity indices and the time spent for light activity, but negatively correlated to the time spent for moderate activity. Nutrient intakes were not significantly correlated to obesity indices. Form the results shown above, although both obese and control groups are from high socioeconomic class, obese children tended to come from family with fat parents. They eat fast and are always eager to eat. They tend to eat more fat but are very different from controls in nutrient intake. Obese children are significantly lower in their actinity compared to controls. So, for the prevention and treatment of childhood obesity, it seems to be more important to increase their activity levels.
Objectives: The objective of this study was held for prevention of coronary artery disease and improvement of health of local community residents by classifying the obesity types of their waist circumference and BMI, and appraising the coronary artery disease risk factors(CRF). Methods: We analyzed the data on the 1,914 adult cases (1,156 male and 758 female) during Nov, 2006 to Mar. 2007 on a general hospital in Daegu city, Korea. The obesity types in this research were classified into normal group, seeming obesity group, abdominal obesity group and obesity group. Also, CRF was classified by normal, mild, moderate, and severe, and each class was given the index from 0 to 3. The coronary artery disease risk factors index(CRFI) was defined as the sum of index, and we defined that if the sum is higher, higher chance of coronary artery disease risk exist. Results: According to the research, by the age group, normal group has higher percentage in age 30 to 40, and obesity group and abdominal obesity group has higher percentage in age 50 to 60. CRFI is increased by order of normal group, seeming obesity group, abdominal obesity group, and obesity group on both male and female groups, and male shows higher index than female on all four groups. CRFI will be influenced by order of obesity group, seeming obesity group, and abdominal obesity group on male, and obesity group, abdominal obesity group, and seeming obesity group on female according to the result of multiple regression between obesity type and CRFI. Conclusion: According to the result from our research, we have to have keen attention to not only seeming obesity group and obesity group, but also abdominal obesity group which has normal waist circumference influence to CRFI. So, those kinds of indexes have to be controled by controling their weight. Also, we believe that health behaviour can improve and CRF can be prevented by the early health care and early health education to those with no abnormal indication on clinical indicator but with abnormal BMI and waist circumference.
The aim of this study was to determine the extent to which sociodemographic and health related life-style variables explain body weight distribution and to understand weight contol behavior. To study this study 298 students were selected, it was consisted of obesity group(101) and control group(197). The average age of subjects was 14.2 and the prevalence of obesity was 2-3 per class as 5.6% among 1,793. 71% among same subject was showed higher weight pattern than last one year, ovesity group which was obesity both in 93 and 94 was 34%. Correlation between body weight(under weight/obesity) and independent variables including sociodemographic factor and health- related life style tested through Multiple Classification Analysis was very significant, explained 36% of the total variance. Sociodemografic and hereditary factors such as education level, age of father and physical features of parents, life style factors as exercise preference and perceived health status showed highly contribution to body weight. Concretely, there were showed a higher obesity prevalence tendency when education level and age of father was high, physical features of parents was obesity. In otherwise, there were showed a higher underweight prevalence tendency when education level and age of father was low. Experience rates of weight control was 53% generally, 84% in obesity group, and 11% in underweight group. There were utilized weight control behaviors through diet method mainly in obesity group, diet and exercise methods in underweight group. There were showed that underweight group are prefer exercise to obesity group. Conclusionally, These findings suggest that education, age, physical features of parents, exercise preference and perceived health status is important factors related to body weight among middle school girls. Therefore, there will be considered as valuable factors when we practice health education and consultation related to body weight. Furthermore it is necessary to provide of various informations about weight control and to develop systematic weight control program.
This study aims to identify the dietary patterns relevant to obesity of Korean women among low income classes. Adults 20-64 years were used as study subjects from the data of 2005 Korea National Health and Nutrition Examination Survey. We compared obese and normal-weight women in terms of their nutrients intake, diet quality and food patterns. Diet quality was assessed by using the Nutritional Adequacy Ratio (NAR) and Index of Nutritional Quality (INQ). Our results showed higher prevalence of obesity among lower socioeconomic status women. In men, there were no significant associations with socioeconomic status and prevalence of obesity. Higher risk of nutritional inadequacy was observed among obese women compared to normal weight women. Obese women showed significantly lower INQ for nutrients such as Ca, Fe, Vitamin A, Thiamin, Riboflavin and Vitamin C compared to other women. They consumed significantly higher amount of rice (p < 0.05) and lower amount of vegetables (p < 0.01). By contrast, obese men from low income classes showed higher intake of those nutrients. Obese men also consumed significantly higher amount of meats than normal weight men. Therefore, this study suggests that gender-specific approaches based on economic situation should be considered in developing the intervention program for managing obesity for low income classes.
This study reports the clinical effects of Korean medicine treatments, herbal medicine, modified fasting, and space spinal conduction exercise and manipulation (SSCEM) on adolescent obesity patient. A 16-year-old male with a body mass index (BMI) 35.5 kg/m2 was diagnosed with class III obesity. We prescribed herbal medicine and modified fasting alternately three times over a period of five months. Additionally, Korean medicine treatments and SSCEM were performed during the treatment period. After treatment, there was a decrease in body weight by 19.86%, from 115.8 kg to 92.8 kg, BMI from 35.5 kg/m2 to 28.6 kg/m2, and body fat mass from 38.1 kg to 17.0 kg. The results of this study showed that Korean medicine treatments, herbal medicine, modified fasting, and SSCEM could be useful in influencing changes in body composition among obese adolescents.
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