• 생명과학회지
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• 제19권10호
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• pp.1403-1409
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• 2009

본 연구에서는 중년비만여성을 대상으로 비만의 발생요인으로 예상되는 요인을 이용하여 비만의 상태를 연령 척도화하여 비만연령(Obesity Age: OA)이라는 연령 추정식을 산출함과 동시에 비만도(비만연령)를 실제의 역연령과 검토하였고 비만연령의 추정식은 다음과 같다. OAS (Obesity Age Score)=$0.106*X_1+0.035*X_2+0.048*X_3+0.041*X_4+0.003*X_5-0.037*X_6-10.66$ (1) ($X_1$: BMI, $X_2$: 체중, $X_3$: 체지방률, $X_4$: 배둘레, $X_5$: 중성지방, $X_6$: $VO_{2max}$) OA (Obesity Age)=7.3*OAS+49.6*(-1) (2) Z=(CA-49.6)(1-0.03) (3) OAc (Obesity Age corrected)=1.03*CA-7.3*OAS+1.47 (4) 그리고 역연령과 추정된 비만연령(Obesity Age corrected: OAc)의 비교에서는 유의한 차이를 나타내지 않아 타당성이 확인되었으며, 총 6개의 측정항목으로 구성된 비만연령을 통해 비만자 개개인의 비만건강도(상태)를 용이하게 평가할 수 있을 것으로 기대하며, 추후에는 다른 집단에서의 적용가능 여부를 알아보기 위해 교차타당성을 검토해야할 것이라고 사료된다.

• Journal of Yeungnam Medical Science
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• 제39권4호
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• pp.285-293
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• 2022

Background: This study was conducted to analyze the effects of low skeletal muscle mass index (SMI) and obesity on aging-related osteoarthritis (OA) in the Korean population. Methods: A total of 16,601 participants who underwent a dual-energy X-ray absorptiometry and 3,976 subjects with knee X-rays according to the modified Kellgren-Lawrence (KL) system were enrolled. Knees of ≥KL grade 2 were classified as radiologic OA. The severity of joint space narrowing (JSN) was classified by X-rays as normal, mild-to-moderate, and severe JSN in radiologic OA. The subjects were grouped as normal SMI (SMI of ≥-1 standard deviation [SD] of the mean), low SMI class I (SMI of ≥-2 SDs and <-1 SD), and low SMI class II (SMI of <-2 SDs). Obesity was defined as a body mass index (BMI) of ≥27.5 kg/m². Results: The modified KL grade and JSN severity were negatively correlated with the SMI and positively correlated with BMI and age. The SMI was negatively correlated with age. JSN severity was significantly associated with a low SMI class compared to a normal SMI, which was more prominent in low SMI class II than class I. Obesity was significantly associated with more severe JSN, only for obesity with a low SMI class. Furthermore, patients with a low SMI class, regardless of obesity, were prone to having more severe JSN. Conclusion: This study suggested that a low SMI class was associated with aging and that an age-related low SMI was more critically related to the severity of JSN in OA.

• 보건교육건강증진학회지
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• 제29권2호
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• pp.23-32
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• 2012

Objectives: This study evaluated the association between osteoarthritis (OA) and health-related quality of life (HRQoL) in elderly Korean women. Methods: We selected participants (n=2,597) aged 50 years or older from Korea National Health and Nutrition Examination Survey [KNHANES] 2005-2008. Demographic and personal characteristics, medical history of OA, and EQ-5D were extracted from the KNHANES data. Results: We found that demographic variables, including age, education level, income, and personal characteristics, were important covariates associated with the prevalence of OA and with HRQoL. In this study, OA was an important factor affecting HRQoL in women. The adjusted odds ratio for HRQoL in participants with OA was 2.92 [(95% confidence interval (CI)=2.43-3.51, p<.001)] in mobility, 2.60 (95% CI=2.17-3.10, p<.001) in pain/discomfort, 2.17 (95% CI=1.78-2.65, p<.001) in usual activities, 1.65 (95% CI=1.22-2.24, p=.001) in self care, and 1.47 (95% CI=1.22-1.77, p<.001) in anxiety/depression. After adjustment of covariates, HRQoL was significantly decreased in participants with OA. Conclusions: Our findings reveal that there is a strong association between OA and HRQoL. Preventing and controlling OA may significantly improve the quality of life for elderly Korean women.

• 디지털융복합연구
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• 제14권7호
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• pp.269-277
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• 2016

본 연구에서는 한국인의 대표성이 있는 자료인 국민건강영양조사 자료를 이용하여 대사증후군 및 그 구성요소들과 골 관절염의 상관관계에 관하여 조사하였다. 여성의 경우, 골 관절염군에서 대사증후군의 유병률이 증가하였으며, 여성에서 대사증후군의 구성요소들, 예를 들어 허리둘레, 중성지질, 수축기 혈압, HDL-콜레스테롤과 골 관절염의 유병률은 통계적으로 유의한 상관관계가 있음이 증명되었다. 또한 생활습관변수 및 사회경제적 변수로 보정하였을 때 대사증후군의 위험요소의 수가 증가할수록 골 관절염의 위험도는 더욱 커지는 경향을 보였다 (p<0.0001). 따라서 이번 연구에서 제시되어진 바와 같이 대사증후군은 골 관절염의 새로운 위험인자로서 인식되어야 하며 골 관절염의 예방과 치료 시 대사증후군 역시 고려되어야 할 요소의 하나로 사료된다.