Browse > Article
http://dx.doi.org/10.14400/JDC.2016.14.7.269

Association of Osteoarthritis with prevalence of Metabolic syndrome: based on 2009-2010 Korean National Health & Nutrition Survey  

Oh, Ji-Eun (Department of Biomedical Laboratory Science, Far East University)
Lim, Se-Hyun (Department of Nursing, Far East University)
Publication Information
Journal of Digital Convergence / v.14, no.7, 2016 , pp. 269-277 More about this Journal
Abstract
This study was attempted to investigate the possible association of osteoarthritis with the metabolic syndrome (MetS) and its components in Korean adults based on the Korean National Health and Nutrition Examination Survey (KNHANES). The prevalence of MetS was significantly increased in OA group in women. To investigate the association between the components for MetS and osteoarthritis, we analyzed the mean values of 5 components of MetS, waist circumference (WC), triglyceride (TG), HDL-cholesterol, systolic blood pressure, and fasting plasma glucose in normal and OA group. In women, WC, TG, HDL, and systolic blood pressure were associated with the development of OA. Moreover, accumulation of components of MetS was significantly related to the prevalence of OA in Korean men and women. These data suggest that MetS might be a novel risk factor for OA and MetS should be taken into account in the prevention and treatment of OA for Korean adults as well.
Keywords
Osteoarthritis; Metabolic syndrome; MetS risk factors; age; abdominal obesity;
Citations & Related Records
Times Cited By KSCI : 5  (Citation Analysis)
연도 인용수 순위
1 D.T. Felson, R.C Lawrence, M.C. Hochberg, T. McAlidon, P. A Dieppe, M. A. Minor, S. N. Blair, B.M. Berman, J. F. Fries, M. Weinberger, K. R. Lorig, J. J. Jacobs, V. Goldberg, "Osteoarthritis: new insights. Part 1: the disease and its risk factors", Ann Intern Med, Vol. 133, pp. 635-646, 2000.   DOI
2 A. A Guccione, D. T Felson, J. J. Anderson, J. M. Anthony, Y. Zhang, P. W. Wilson, M. Kelly-Hayes, P. A. Wolf, B. E. Kreger, W. B. Kannel, "The effects of specific medical conditions on the functional limitations of elders in the Framingham Study", Am J Public Health, Vol. 84, pp. 351-358, 1994.   DOI
3 D. T. Felson, Y. Zhang, "An update on the epidemiology of knee and hip osteoarthritis with a view to prevention", Arthritis Rheum, Vol.41, pp. 1343-1355, 1998.   DOI
4 J. D. Katz, S. Agrawal, M. Velasquez, "Getting to the heart of the matter: osteoarthritis takes its place as part of the metabolic syndrome", Curr Opin Rheumatol, Vol. 22, pp. 512-519, 2010.   DOI
5 R. F. Loeser, "Aging and osteoarthritis", Curr Opin Rheumatol, Vol. 23, pp. 492-496, 2011.   DOI
6 L.W. Cho, "Metabolic syndrome", Singapore Med J, Vol. 52, pp. 779-785, 2011.
7 S. M. Grundy, J. I. Cleeman, S. R. Daniels, K. A. Donato, R. H. Eckel, B. A. Franklin, D. J. Gordon, R. M. Krauss, P. J. Savage, S. C. Jr. Smith, J.A. Spertus, F. Costa, "Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement", Circulation, Vol. 112, pp. 2735-2752, 2005.   DOI
8 S. M. Grundy, "Metabolic syndrome: a multiplex cardiovascular risk factor", J Clin Endocrinol Metab, Vol. 92, pp. 399-404, 2007.   DOI
9 J. Jeppesen, T. W. Hansen, S. Rasmussen, H. Ibsen, C. Torp-Pedersen, S. Madsbad, "Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease: a population-based study", J Am Coll Cardiol, Vol. 49, pp. 2112-2119, 2007.   DOI
10 S. Malik, N. D. Wong, S. S. Franklin, T. V. Kamath, G. J. L'Italien, J. R. Pio, G. R. Williams, "Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults", Circulation, Vol. 110, pp. 1245-1250, 2004.   DOI
11 P. W. Wilson, R. B. D'Agostino, H. Parise, L. Sullivan, J. B. Meigs, "Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus", Circulation, Vol. 112, pp. 3066-3072, 2005.   DOI
12 C. M. Alexander, P. B. Landsman, S. M. Teutsch, S. M. Haffner, "NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older", Diabetes, Vol. 52, pp. 1210-1214, 2003.   DOI
13 D. J. Hart, T.D. Spector, "The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study". J Rheumatol, Vol. 20, pp.331-335, 1993.
14 J. L. van Saase, J. P. Vandenbroucke, L. K. van Romunde, H. A.Valkenburg, "Osteoarthritis and obesity in the general population. A relationship calling for an explanation", J Rheumatol, Vol. 15, pp. 1152-1158, 1988.
15 D. Leroith, "Pathophysiology of the metabolic syndrome: implications for the cardiometabolic risks associated with type 2 diabetes", Am J Med Sci, Vol. 343, pp. 13-16, 2012.   DOI
16 D. J. Hart, D. V. Doyle, T. D. Spector, "Association between metabolic factors and knee osteoarthritis in women: the Chingford Study", J Rheumatol, Vol. 22, pp. 1118-1123, 1995.
17 N. Yoshimura, S. Muraki, H. Oka, H. Kawaguchi, K. Nakamura, T. Akune, "Association of knee osteoarthritis with the accumulation of metabolic risk factors such as overweight, hypertension, dyslipidemia, and impaired glucose tolerance in Japanese men and women: the ROAD study", J Rheumatol, Vol. 38, pp. 921-930, 2011.   DOI
18 J. H. Kellgren, "Osteoarthrosis in patients and populations", Br Med J, Vol. 2, pp. 1-6, 1961.   DOI
19 M.A. Cimmino, M. Cutolo, "Plasma glucose concentration in symptomatic osteoarthritis: a clinical and epidemiological survey", Clin Exp Rheumatol, Vol. 8, pp. 251-257, 1990.
20 G. Singh, J. D. Miller, F. H. Lee, D. Pettitt, M. W. Russell, "Prevalence of cardiovascular disease risk factors among US adults with self-reported osteoarthritis: data from the Third National Health and Nutrition Examination Survey", Am J Manag Care, Vol. 8, S pp. 383-391, 2002.
21 R. A. Puenpatom, T. W. Victor, "Increased prevalence of metabolic syndrome in individuals with osteoarthritis: an analysis of NHANES III data", Postgrad Med, Vol. 121, pp. 9-20, 2009.   DOI
22 S. H. Lee, "Relationship between obesity and dental caries", J Dig. Conv., Vol. 12, No. 12, pp. 633-641, 2014   DOI
23 Y. M. Kim, S. H. Kang, "Convergence analysis of determinants affecting on geographic variations in the prevalence of arthritis in Korean women using data mining", J Dig. Conv., Vol. 13, No. 5, pp. 277-288, 2015.
24 T. Y. Lee, S. M. Choi, "Convergence study for relationship between cholesterol level on serum and depression in Korean adults", J Dig. Conv., Vol. 13, No. 5, pp. 269-276, 2015.   DOI
25 W. Y. Kim, J. E. Kim, Y. J. Choi, K. B. Huh, "Nutritional risk and metabolic syndrome in Korean type 2 diabetes mellitus", Asia Pac J Clin Nutr, Vol. 17, Suppl 1. pp. 47-51, 2008.
26 Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation, Vol. 106, pp. 3143-3421, 2002.
27 S. Y. Lee, H. S. Park, D. J. Kim, J. H, Han, S. M. Kim, G. J. Cho, D. Y. Kim, H. S. Kwon, S. R. Kim, C. B. Lee, S. J. Oh, C. Y. Park, H. J. Yoo, "Appropriate waist circumference cutoff points for central obesity in Korean adults", Diabetes Res Clin Pract, Vol. 75, pp. 72-80, 2007.   DOI
28 J. L. Busija, L. Bridgett, S. R. Williams, R. H. Osborne, R. Buchbinder, L. March L, M. Fransen, "Osteoarthritis", Best Pract Res Clin Rheumatol, Vol. 24, pp. 757-768, 2010.   DOI
29 DOI: http://www.hindawi.com/journals/jl/2011/721686/
30 J. Ye, "Emerging role of adipose tissue hypoxia in obesity and insulin resistance", Int J Obes (Lond), Vol. 33, pp. 54-66, 2009.   DOI
31 A .J. Hanley, A. Festa, R. B. Jr. D'Agostino, L. E. Wagenknecht, P.J. Savage, R. P. Tracy, M. F. Saad, S. M. Haffner, "Metabolic and inflammation variable clusters and prediction of type 2 diabetes: factor analysis using directly measured insulin sensitivity". Diabetes, Vol. 53, pp. 1773-1781, 2004.   DOI
32 F. B. Hu, J. B. Meigs, T. Y. Li, N. Rifai, J. E. Manson, "Inflammatory markers and risk of developing type 2 diabetes in women", Diabetes, Vol. 53, pp. 693-700, 2004.   DOI
33 B. Gustafson, "Adipose tissue, inflammation and atherosclerosis", J Atheroscler Thromb, Vol. 17, pp. 332-341, 2010.   DOI
34 K. Lee, J. A. Villena, Y. S. Moon, K. H. Kim, S. Lee, C. Kang, H. S. Sul, "Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1)", J Clin Invest, Vol. 111, pp. 453-461, 2003.   DOI
35 E. Toussirot, G. Streit, D. Wendling, "The contribution of adipose tissue and adipokines to inflammation in joint diseases", Curr Med Chem, Vol. 14, pp. 1095-1100, 2007.   DOI
36 J. Bondeson, A. B. Blom, S. Wainwright, C. Hughes, B. Caterson, W. B. van den Berg, "The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis", Arthritis Rheum, Vol. 62, pp. 647-657, 2010.
37 R. Lago, R. Gomez, F. Lago, J. Gomez-Reino, O. Gualillo, "Leptin beyond body weight regulation--current concepts concerning its role in immune function and inflammation", Cell Immunol, Vol. 252, pp. 139-145, 2008.   DOI
38 M. Sowers, C. A. Karvonen-Gutierrez, R. Palmieri-Smith, J. A. Jacobson, Y. Jiang, J. A. Ashton-Miller, "Knee osteoarthritis in obese women with cardiometabolic clustering", Arthritis Rheum, Vol. 61, pp. 1328-1336, 2009.   DOI
39 Hye-Jung Choi, Soon-Gi Back, "A Study on Depressive disposition by Convergence approach of Leisure History and Family situation in Elderly Women", Journal of the Korea Convergence Society, Vol. 6, No. 5, pp. 295-302, 2015.   DOI
40 Bae-won Lee, Jae-chul Song, Hun-young Ha, Sang-hyo Sim, Jae-hun Shim, "A Study on Obesity-related Factors Through the Convergence of Body Mass Index (BMI) and Fat-CT in Middle-aged Women Living in Incheon", Journal of the Korea Convergence Society, Vol. 6, No. 3, pp. 19-28, 2015.   DOI