• Interdisciplinary Bio Central
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• v.5 no.1
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• pp.1.1-1.8
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• 2013

High quality publicly-available transcriptomic data representing relationships in gene expression across a diverse set of biological conditions is used as a context network to explore transcriptomics of the CNS. The context network, 18367Hu-matrix, contains pairwise Pearson correlations for 22,215 human genes across18,637 human tissue samples1. To do this, we compute a network derived from biological samples from CNS cells and tissues, calculate clusters of co-expressed genes from this network, and compare the significance of these to clusters derived from the larger 18367Hu-matrix network. Sorting and visualization uses the publicly available software, MetaOmGraph (http://www.metnetdb.org/MetNet_MetaOm-Graph.htm). This identifies genes that characterize particular disease conditions. Specifically, differences in gene expression within and between two designations of glial cancer, astrocytoma and glioblastoma, are evaluated in the context of the broader network. Such gene groups, which we term outlier-networks, tease out abnormally expressed genes and the samples in which this expression occurs. This approach distinguishes 48 subnetworks of outlier genes associated with astrocytoma and glioblastoma. As a case study, we investigate the relationships among the genes of a small astrocytoma-only subnetwork. This astrocytoma-only subnetwork consists of SVEP1, IGF1, CHRNA3, and SPAG6. All of these genes are highly coexpressed in a single sample of anaplastic astrocytoma tumor (grade III) and a sample of juvenile pilocytic astrocytoma. Three of these genes are also associated with nicotine. This data lead us to formulate a testable hypothesis that this astrocytoma outlier-network provides a link between some gliomas/astrocytomas and nicotine.

• Coupled systems mechanics
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• v.9 no.2
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• pp.111-123
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• 2020

Wastewater treatment plants (WWTPs) with activated sludge system are widely used throughout the most common technologies in the world. Most treatment plants require optimization of certain treatment processes using dynamic modeling. A lot of examples of dynamic simulations require reliable data base of diurnal variation of the inflow and typical concentrations of parameters such as Chemical Oxygen Demand (COD), Total Kjeldahl Nitrogen (TKN), etc. Such detailed data are not available, which leads to problemsin the application of dynamic simulations. In many examples of plants, continuous flow measurements are only performed after the primary clarifier, whereas measurements from influent to the plant are missing, as is the case with the examples in this paper. In some cases, a simpler, faster and cheaper way can be applied to determine influent variations, such as the "HSG-Sim" method ("Hochschulgruppe Simulation"). "Hochschulgruppe Simulation" is a group of researchers from Germany, Austria, Switzerland, Luxembourg, Netherlands and Poland (see http://www.hsgsim.org). This paper presents a model for generating daily variations of inflow and concentration of municipal wastewater quality parameters, applied to several existing WWTPs in Bosnia and Herzegovina (B&H). The main goal of the applied method is to generate realistic influent data of the existing plants in B&H, in terms of flow and quality, without any prior comprehensive survey and measurements at the site. The examples of plants show the influence of overflow facilities on the dynamics of input flow and quality of wastewater, and a strong influence of the problems of the sewerage systems.

• Proceedings of the Korean Institute of Resources Recycling Conference
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• 2006.05a
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• pp.78-85
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• 2006

In textile industries, waste effluent containing zinc is generated during the manufacture of rayon yarn from the wood pulp or cotton linters. Due to the strict environmental regulations and the presence of toxic metallic and other constituents, the discharge of industrial effluents in the sewage or disposal of solid sludge as landfill is restricted. Before recycling of zinc as zinc sulphate solution to the spinning-bath of the rayon manufacturing plant the zinc sulphate solution must be free from calcium, which is deleterious to the process as gypsum precipitates with the increase in concentration and forms scale in the bath. In the present work an attempt has been made to develop a process following solvent extraction technique using thiophosphinic extractants, Cyanex 272 and 302 modified with isodecanol and diluted in kerosene to recover zinc from rayon effluent. Various process parameters viz. extraction of zinc from different concentration of solution, distribution ratio, selective extraction, O/A ratio on extraction and stripping from the loaded organic, complex formation in the organic phase etc. have been studied to see the feasibility of the process. The extractant Cyanex 302 has been found selective for the recovery of 99.99% of zinc from the effluent above equilibrium pH 3.4 maintaining the O/A ratio of 1/30 leaving all the calcium in the raffinate. It selectively extracted zinc in the form of complex $[R_{2}Zn.3RH]_{org}$ and retained all the calcium in the aqueous raffinate. The zinc from the loaded Cyanex 302 can be stripped with 10% sulphuric acid at even O/A ratio of 10 without affecting the stripping efficiency. The stripped solution thus obtained could be recycled in the spinning bath of the rayon plant. The raffinate obtained after the recovery of zinc could be disposed safely without affacting environment.

• Proceedings of the Membrane Society of Korea Conference
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• 1998.10a
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• pp.15-18
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• 1998

Membrane reactors are systems which combine a chemical reactor with a membrane separation process allowing to carry out simultaneously conversion and product separation. The catalyst can be immobilized on the membrane or simply compartmentalized in a reaction space by the membrane. Membrane reactors are today investigated to produce optically pure isomers and/or resolve racemic mixture of enantiomers. The interest towards these systems is due to the increasing demand of enantiomerically pure compounds to be used in the pharmaceutical, food, and agrochemical industries. In fact, enantiomers can have different biological activities, which often influence the efficacy or toxicity of the compound. On the basis of current literature there are basically two schemes on the use of membrane technology to produce enantiomers. In one case, the membrane itseft is intrinsically enantioselective: the membrane is the chiral system which selectively separates the wanted isomer on the basis of its conformation. In the other, a kinetic resolution using an enantiospecific biocatalyst is combined with a membrane separation process; the membrane separates the product from the substrate on the basis of their relative chemical properties (i.e. solubility). This kind of configuration is widely used to carry out kinetic resolutions of low water soluble substrams in biphasic membrane reactors [Giomo, 1995, 1997; Lopez, 1997]. These are systems where enzyme-loaded membranes promote reactions between two separate phases thanks to the properties of enzymes, such as lipases, to catalyse reactions at the org ic/aqueous interface; the two phases are maintained in contact and separated at the membrane level by operating at appropriate transmembrane pressure. A schematic representation of biphasic membrane reactor is shown in figure 1, while an example of enantiospecific reaction and product separation carried out with these systems is reported in figure 2.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.4-5
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• 2010

The surface phonon is defined as a coherent vibrational excitation of surface atoms propagating along the surface. It is characterized by a phonon dispersion curves, which were extensively studied in 1990's using helium atom scattering and high-resolution electron-energy-loss spectroscopy (HREELS)[1].The understanding is mainly based on the theoretical framework of a classical bond model or cluster calculations. The recent sample preparation and first principles calculations open the naval way to deep insight for surface phonon problems. The surface phonon dispersion on the hydrogen-terminated Si(111)-($1{\times}1$) surface [H:Si(111)] is the typical system and already reported experimentally [2] and theoretically [3], although the understandingis incomplete. The sample contaminated by the oxygen atoms on the surface and the calculations were also classical. In this study, firstly, we have prepared an ultra-clean H:Si(111) surface [4] and measured the surface phonon dispersion curvesusing HREELS. Secondly, we have performed first-principles density functional calculations with the projector augmented wave functionals, as implemented in VASP, using generalized gradient approximations. We used aslab of six silicon layers and both top and bottom surfaces were terminated with hydrogen atoms. Finally, we have compared with the surface phonon dispersion of deuterium-terminatedSi(111)-($1{\times}1$) surface[5] and led to our conclusions. The Si-H stretching and the bending modes are observed at 258.5 and 78.2 meV, respectively. These energies are the same as the previously reported values [2], but the energy-loss peaks at the lower energy regions are dramatically shifted. Through this combination study, we have formulated the procedure of preparing ultra-clean H:Si(111)/D:Si(111), which was confirmed by HREELS vibrational analysis. The Si surface will be utilized for further nano-physics research as well as for the materials for nano-fubrication.

• Economic and Environmental Geology
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• v.32 no.6
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• pp.585-597
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• 1999

Plutomic rocks of the Mabogsan, located in the southestern part of the Koheung Eup are composed of granite gneiss, diorite, biotite grantie and granophyre. On the basis of Rb-Ba-Sr diagram, the diorires are plotted from granodiorite to quartz diortie, the biotite granites from granodiortie to anomalous granite and the granophyres in normal granite filed. The plutonic rocks tend to show the I-type characteristics in terns of ACF diagram, $K_2O-Na_2O$ diagram and $Al_2O_3/Na_2O+K_2O+CaO$ diafram, while have values of ilmenite series in magnetic subseptibility. The plutons could have formed in the tectonic environment of VAG+COLG+ORG based on the silica vs. trace element diagrams. Gold contents with major and trace elements have been determined for 21 granophyres, 13 biotite granites and 4 diorites are; (1) for the diorite, the rangs is 0.508~1.73 ppb with an average of 0.5ppb;(2) for the biotite granites, the range is 0.449~13.5ppb with an average of 3 ppb;(3)for the granphyres, the range is 0.508~23.1ppb with an average of 4.5ppb. The gold content of the studied plutons tends to increase from mafic to felsic rocks. Gold contents tend to show positive correlations with those of Ag and Zn, negative correlations with those of As, Ba and Rb. The copper contents of the plutons are comparatively high. Average copper contents of diorite, biotite granite and granophyre are 710ppm, 587ppm and 484ppm, respectively. The copper contents of the plutons tend to have good correlations with those of Ag, Bi and Pb.

• Journal of Animal Reproduction and Biotechnology
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• v.36 no.3
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• pp.154-161
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• 2021

A number of Korean Chicken breeds were registered in Domestic Animal Diversity Information System (DAD-IS, http://dad.fao.org/) of the Food and Agriculture Organization (FAO). Evaluation of genetic diversity and relationship of local breeds is an important factor towards the identification of unique and valuable genetic resources. Therefore, this study aimed to analysis the genetic diversity and relationship of 22 Korean Chicken breeds using 12 microsatellite (MS) markers. The mean number of alleles for each variety was 5.52, ranging from a 3.75 (Leghorn F; NF) to a 7.0 (Ross). The most diverse breed was the Hanhyup3 (HCC), which had the highest expected heterozygosity (H_Exp) (0.754) and polymorphic information content (PIC) (0.711). The NF was the least diverse population, having the lowest H_Exp (0.467) and PIC (0.413). As a result of the principal coordinates analysis (PCoA) and factorial correspondence analysis (FCA) confirmed that Hy-line Brown (HL) and Lohmann Brown (LO) are very close to each other and that Leghorn and Rhode Island Red (RIR) are clearly distinguished from other groups. Thus, the reliability and power of identification using 12 types of MS markers were improved, and the genetic diversity and probability of individual discrimination were confirmed through statistical analysis. This study is expected to be used as basic data for the identification of Korean chicken breeds, and our results indicated that these multiplex PCR marker sets will have considerable applications in population genetic structure analysis.

• The Korean Journal of Archival Studies
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• no.49
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• pp.121-173
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• 2016

An election is a major event in a country that elects the people's representatives. Currently, Korea's electoral system has a structure that limits the exclusion of the minority's opinion. Also, it has strengthened the monopoly of major political parties. Despite the harsh conditions, Green Party Korea has proposed an alternative to prevent even the minority from being excluded by practicing direct democracy and expanding proportional representation through the institutionalization of the democratic process within the party. Election campaigns should thus reflect this orientation of Green Party Korea. The local elections and the national elections reflect Korea's political and social status and show the course over two minority parties beyond such limits. Moreover, they provide evidence of the activities of Green Party Korea. The paper analyzes how the election archives of the party hold the values of democracy, how minor parties jump to another because of the unfavorable election system, and how the archives of Green Party Korea reflect its values on the political history of Korea.

• Maritime Security
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• v.1 no.1
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• pp.175-214
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• 2020

Previous studies cannot effectively explain the rise of piracy in Somalia and NIgeria. First, there is a lack of explanation for the process that from a small maritime robbery into a org anized pirate g roup. Second, it is difficult to explain the low level of piracy in countries with extreamly poor conditions, from Somalia to Nigeria. In this study, I argue that the more severe foreign countries infringe on economic maritime sovereignty in vulnerable countries, the higher the intensity and frequency of piracy. If the infringement of economic maritime sovereignty caused by foreign groups occurs in a fragile state, the government could not respond to the acts of foreign groups, resulting in increased damage to maritime people, deteriorating the regional economic situation. As hostility grows, a culture favorable to piracy is created, which is actively utilized by local forces to inspire the people's hostility, and a favorable environment for piracy emerges in a way that responds politically to foreign powers. In Somalia and Nigeria, the infringement of economic maritime sovereignty by foreign groups emerged severe. And based on the stagnation of the local economy and hostility toward foreign groups, favorable conditions were formed for piracy, resulting in the rise of piracy. Meanwhile, Somalia's neighbor, one of the most fragile states in the world, Yemen have not suffered piracy. Also, the foreign infringement to the maritime economic sovereignty has rarely been observed.

• Imaging Science in Dentistry
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• v.51 no.2
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• pp.137-148
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• 2021

Purpose: This study aimed to assess the computer monitors used for analysis and interpretation of digital radiographs within the clinics of the Oral Health Centre of Western Australia. Materials and Methods: In total, 135 computer monitors(3 brands, 6 models) were assessed by analysing the same radiographic image of a combined 13-step aluminium step wedge and the Artinis CDDent 1.0^® (Artinis Medical Systems B.V.^®, Elst, the Netherlands) test object. The number of steps and cylindrical objects observed on each monitor was recorded along with the monitor's make, model, position relative to the researcher's eye level, and proximity to the nearest window. The number of window panels blocked by blinds, the outside weather conditions, and the number of ceiling lights over the surgical suite/cubicle were also recorded. MedCalc^® version 19.2.1 (MedCalc Software Ltd^®, Ostend, Belgium, https://www.medcalc.org; 2020) was used for statistical analyses(Kruskal-Wallis test and stepwise regression analysis). The level of significance was set at P<0.05. Results: Stepwise regression analysis showed that only the monitor brand and proximity of the monitor to a window had a significant impact on the monitor's performance (P<0.05). The Kruskal-Wallis test showed significant differences (P<0.05) in monitor performance for all variables investigated, except for the weather and the clinic in which the monitors were placed. Conclusion: The vast performance variation present between computer monitors implies the need for a review of monitor selection, calibration, and viewing conditions.