• Title/Summary/Keyword: ODe

검색결과 137건 처리시간 0.03초

The Synergism of Human Lactobacillaceae and Inulin Decrease Hyperglycemia via Regulating the Composition of Gut Microbiota and Metabolic Profiles in db/db Mice

  • Peifan Li;Tong Tong;Yusong Wu;Xin Zhou;Michael Zhang;Jia Liu;Yongxin She;Zuming Li;Yongli Li
    • Journal of Microbiology and Biotechnology
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    • 제33권12호
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    • pp.1657-1670
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    • 2023
  • This study aimed to evaluate the effects of Limosilactobacillus fermentum and Lactiplantibacillus plantarum isolated from human feces coordinating with inulin on the composition of gut microbiota and metabolic profiles in db/db mice. These supplements were administered to db/db mice for 12 weeks. The results showed that the Lactobacillaceae coordinating with inulin group (LI) exhibited lower fasting blood glucose levels than the model control group (MC). Additionally, LI was found to enhance colon tissue and increase the levels of short-chain fatty acids. 16S rRNA sequencing revealed that the abundance of Corynebacterium and Proteus, which were significantly increased in the MC group compared with NC group, were significantly decreased by the treatment of LI that also restored the key genera of the Lachnospiraceae_NK4A136_group, Lachnoclostridium, Ruminococcus_gnavus_group, Desulfovibrio, and Lachnospiraceae_UCG-006. Untargeted metabolomics analysis showed that lotaustralin, 5-hydroxyindoleacetic acid, and 13(S)-HpODE were increased while L-phenylalanine and L-tryptophan were decreased in the MC group compared with the NC group. However, the intervention of LI reversed the levels of these metabolites in the intestine. Correlation analysis revealed that Lachnoclostridium and Ruminococcus_gnavus_group were negatively correlated with 5-hydroxyindoleacetic acid and 13(S)-HpODE, but positively correlated with L-tryptophan. 13(S)-HpODE was involved in the "linoleic acid metabolism". L-tryptophan and 5-hydroxyindoleacetic acid were involved in "tryptophan metabolism" and "serotonergic synapse". These findings suggest that LI may alleviate type 2 diabetes symptoms by modulating the abundance of Ruminococcus_gnavus_group and Lachnoclostridium to regulate the pathways of "linoleic acid metabolism", "serotonergic synapse", and" tryptophan metabolism". Our results provide new insights into prevention and treatment of type 2 diabetes.

시조창 분류고 (Research on Classifying the 'Sijochang', or Korean Ode Narrative Song)

  • 신웅순
    • 한국시조학회지:시조학논총
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    • 제24집
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    • pp.223-258
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    • 2006
  • 본고는 음악상으로서의 시조 분류이다. 잣수에 의한 문학상 분류와는 달리 시조창은 선율에 따라 달라진다. 문학상으로는 단시조 중시조 장시조의 분류가 일반적이나 시조창은 평시조 지름시조 사설시조로의 분류가 일반적이다. 같은 시조창이면서 다른 명칭으로 불리워지고 있는 경우가 있고 다른 종류이면서 같은 명칭으로 불리워지고 있는 경우가 있어 시조창의 명칭에 대한 논의가 필요한 실정에 놓여있다. 몇몇 국악인들에 의해 시도는 되고 있으나 개념에 대한 구체적인 논증 없이 이루어지고 있어 이에 대한 체계적인 고구가 필요한 실정이다. 현재의 번다한 명칭들을 정리하고 시조의 분류 체계를 세우고자하는 데에 본고의 목적이 있다. 필자는 고악보와 현행 시조보, 기존 이론을 검토, 평시조 계열 지름시조 계열 사설시조 계열로 일단 3대별하고 여기에 현재 불리워지고 있는 시조창들이 어떤 계열에 속하는 것인가를 몇 가지 원칙에 의해 분류해보았다. 필자가 조사한 현행 시조 명칭 67가지를 필요한 16개의 명칭으로 줄여 분류했다. 이는 현재 불리워지고 있는 명칭들이 같은 시조이면서 표음이 다른 것도 있고 다른 시조이면서 같은 명칭으로 불리워지는 것들도 있다. 이의 복잡, 번다함을 피하기 위해 문학과 음악상의 개념을 고려, 일부 용어들을 정리했다. 1) 평시조 계열 : 평시조, 중허리 시조, 우조시조, 파연곡 2) 지름시조 계열 : 지름시조, 남창지름시조, 여창지름시조, 반지름시조, 온지름시조, 우조지름시조, 사설지름시조, 휘몰이 시조 3) 사설시조 계열 : 사설시조, 반사설시조, 각시조, 좀는 평시조 아직도 배자, 형태, 음계, 타장르와의 영향 관계 등 적지 않은 음악상의 작업들이 남아있고 그에 대한 이론 축척이 시급한 실정이다. 이러한 음악적인 부분들은 전문가, 국악인들의 면밀한 검토와 연구를 필요로 하고 있다 차후의 논문을 기대할 수밖에 없음을 밝혀둔다.

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DOMAIN OF EXISTENCE OF A PERTURBED CAUCHY PROBLEM OF ODE

  • Kim, June Gi
    • Korean Journal of Mathematics
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    • 제10권1호
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    • pp.53-58
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    • 2002
  • In this paper we consider the Cauchy problem $$dx(t)/dt=x(t)^n,\;x(0)=x_0$$. The domain of existence is lower semicontinuous for perturbations of the data. We present a simple formula for the time of existence which is exact when there exists no perturbations.

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A simple model for a mush

  • Yang, Young-Kyun
    • 대한수학회보
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    • 제34권4호
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    • pp.583-593
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    • 1997
  • We have derived a simple ODE system for the mush by assuming that the temperature T, the solid fraction $\phi$ and the vertical component $\omega$ of the velocity, depend on z only. Analytical solutions of the system have presentd in case of $\omega << 1 and \phi << 1$.

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Elasticity solution and free vibrations analysis of laminated anisotropic cylindrical shells

  • Shakeri, M.;Eslami, M.R.;Yas, M.H.
    • Structural Engineering and Mechanics
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    • 제7권2호
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    • pp.181-202
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    • 1999
  • Dynamic response of axisymmetric arbitrary laminated composite cylindrical shell of finite length, using three-dimensional elasticity equations are studied. The shell is simply supported at both ends. The highly coupled partial differential equations are reduced to ordinary differential equations (ODE) with variable coefficients by means of trigonometric function expansion in axial direction. For cylindrical shell under dynamic load, the resulting differential equations are solved by Galerkin finite element method, In this solution, the continuity conditions between any two layer is satisfied. It is found that the difference between elasticity solution (ES) and higher order shear deformation theory (HSD) become higher for a symmetric laminations than their unsymmetric counterpart. That is due to the effect of bending-streching coupling. It is also found that due to the discontinuity of inplane stresses at the interface of the laminate, the slope of transverse normal and shear stresses aren't continuous across the interface. For free vibration analysis, through dividing each layer into thin laminas, the variable coefficients in ODE become constants and the resulting equations can be solved exactly. It is shown that the natural frequency of symmetric angle-ply are generally higher than their antisymmetric counterpart. Also the results are in good agreement with similar results found in literatures.

NONLINEAR ANALYSIS OF SELF-EXCITED VIBRATION IN WHEELED TRACTOR VEHICLE'S DRIVELINE

  • Li, X.H.;Zhang, J.W.;Zeng, C.C.
    • International Journal of Automotive Technology
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    • 제7권5호
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    • pp.535-545
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    • 2006
  • A nonlinear analysis of torsional self-excited vibration in the driveline system for wheeled towing tractors was presented, with a 2-DOF mathematical model. The vibration system was described as a second-order ordinary differential equation. An analytical approach was proposed to the solution of the second-order ODE. The mathematical neighborhood concept was used to construct the interior boundary and the exterior boundary. The ODE was proved to have a limit cycle by using $Poincar\'{e}-Bendixson$ Annulus Theorem when two inequalities were satisfied. Because the two inequalities are easily satisfied, the self-excited vibration is inevitable and even the initial slip rate is little. However, the amplitude will be almost zero when the third inequality is satisfied. Only in a few working modes of the towing tractor the third inequality is not satisfied. It is shown by experiments that the torsional self-excited vibration in the driveline of the vehicle is obvious.

HyperNEAT를 이용한 4족 보행 로봇의 이동 제어 (Locomotion Control of 4 Legged Robot Using HyperNEAT)

  • 장재영;현수환;서기성
    • 한국지능시스템학회논문지
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    • 제21권1호
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    • pp.132-137
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    • 2011
  • 4족 보행로봇은 보행 안정성이 높아서 향후 다양한 분야에 활용이 기대되며, 효율적인 보행을 위한 걸음새의 생성과 제어가 중요하다. 특히, 다양한 로봇 모델들에 대한 수요와 여러 가지 걸음 동작의 필요성으로 인하여 자동적인 걸음새 생성기법이 요구된다. 본 논문에서는 HyperNEAT(Hypercube-based NeuroEvolution of Augmenting Topologies)를 사용하여 지형변화에 적응 가능한 4족 보행로봇의 걸음새를 생성하고, 바이올로이드로 구성된 4족 보행로봇에 대하여 ODE 기반의 Webots 시뮬레이션을 통해서 보행 실험을 수행하고 결과를 분석한다.