• Title/Summary/Keyword: OD

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Anti-stress Effect by the Treatment of Vitamin C (Vitamin C 투여에 의한 항스트레스 효과)

  • 오찬호;최동성
    • KSBB Journal
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    • v.8 no.5
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    • pp.424-430
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    • 1993
  • The anti-stress effect by the treatment of vitamin C was investigated in this study. The treatment of ascorbic acid in the presence of $Cu^{2+}$ion induced strong time- and dose-dependent degradation of hitamine, and also the addition of histamine accelerated time-dependent decomposition of ascorbic acid in vitro. The treatment of ascorbic acid in $ODS^{od}/_{od}$rats, which cannot synthesize ascorbic acid, significantly decreased the urinary histamine. The protreatment of ascorbic acid, dexamethasone and promethazine inhibited the lethal effect induced by immobilization stress, but that of dimethylsulfoxide did not. The addition of ascorbic and to a culture of spleen cells of $ODS^{od}/_{od}$rats significantly increased the Con A-dependent T lymphocyte proliferation.

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Analysis of Passenger Movement Patterns Using Subway OD Data (도시철도 출·도착데이터를 이용한 승객이동 패턴 분석)

  • Baik, Euiyoung;Cho, Jae Hee;Kim, Dong-Geon
    • Journal of the Korea Convergence Society
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    • v.10 no.12
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    • pp.315-325
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    • 2019
  • The purpose of this study is to design and construct a data mart that anyone can easily analyze subway OD movement patterns. Subway OD data of the year 2017 was downloaded from the Seoul Open Data Plaza and used as the source data. A multidimensional model was designed, and Gaussian mixed cluster analysis and visualization analysis using Tableau were performed. Interestingly, movement between suburban and Seoul accounts for 23% of the total traffic. The passengers of Suwon Station move to the suburbs much more than Seoul, while Pangyo Station mostly moves to Seoul. As a result of Gaussian mixed cluster, eight clusters of OD segments were found, and the characteristics of each cluster were characterized by segment distance and passenger size.

A Study on the Analysis of Spatial Characteristics with Respect to Regional Mobility Using Clustering Technique Based on Origin-Destination Mobility Data (기종점 모빌리티 데이터 기반 클러스터링 기법을 활용한 지역 모빌리티의 공간적 특성 분석 연구)

  • Donghoun Lee;Yongjun Ahn
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.22 no.1
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    • pp.219-232
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    • 2023
  • Mobility services need to change according to the regional characteristics of the target service area. Accordingly, analysis of mobility patterns and characteristics based on Origin-Destination (OD) data that reflect travel behaviors in the target service area is required. However, since conventional methods construct the OD data obtained from the administrative district-based zone system, it is hard to ensure spatial homogeneity. Hence, there are limitations in analyzing the inherent travel patterns of each mobility service, particularly for new mobility service like Demand Responsive Transit (DRT). Unlike the conventional approach, this study applies a data-driven clustering technique to conduct spatial analyses on OD travel patterns of regional mobility services based on reconstructed OD data derived from re-aggregation for original OD distributions. Based on the reconstructed OD data that contains information on the inherent feature vectors of the original OD data, the proposed method enables analysis of the spatial characteristics of regional mobility services, including public transit bus, taxi and DRT.

Characterization for Blend of Siloxane Prepolymer onto Epoxy Resin (Siloxane Prepolymer의 에폭시수지 블렌드 특성)

  • Kim, Kong-Soo;Park, Jun-Ha;Shin, Jae-Sup;Kim, Yeong-Jun
    • Elastomers and Composites
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    • v.32 no.3
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    • pp.179-185
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    • 1997
  • In solution and melting state, SiOD prepolymer was prepared by cured excess DDM with epoxy-terminated siloxane oligomers to control phase separation when DGEBA was blended with PDMS. DGEBA/SiOD prepolymer was also cured at $150^{\circ}C$ for 3hrs. Mechanical and thermal properties of the cured prepolymer specimen were investigated. DGEBA/SiOD60 specimen blended SiOD prepolymer had the best flexural strength, modulus and impact strength. To show crack-formation procedure to morphology, DGEBA/DDM neat specimen was flowed homogeneously in direction of crack energy, whereas DGEBA/SiOD$(30{\sim}60)$ specimen showed heterogeneously dispersed particles and scattered domain of crack energy, but DGEBA/SiOT specimen showed homogeneous phase.

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Improving Data Input of ECO2-OD Program Utilizing BIM (BIM을 이용한 ECO2-OD 프로그램의 정보입력 개선)

  • Kang, Min-Su;Kim, Ka-Ram;Yu, Jung-Ho
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2013.05a
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    • pp.205-207
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    • 2013
  • In a situation that building energy consumption is increasing worldwide, the research utilizing BIM technology to analyze building energy has been actively conducted. On the other hand, data input method of the building energy analysis has been still manually entered. This paper proposed a improved input method of required information for building energy analysis using the ECO2-OD program. As a result, although some required information of BIM based design software could be almost entered when it comes to general information and architectural sector, it has a problem to be handled in HVAC sector. Therefore, in the both of general and architectural sectors, the BIM information from the BIM-based design software could be directly used to automatically and systematically input the information. Future research should be studied the algorism and method in connection with data exchange to utilize input method of ECO2-OD from BIM data.

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Estimation of Electrical Parameters of OD Organic Semiconductor Diode from Measured I-V Characteristics

  • Moiz, Syed Abdul;Ahmed, Mansoor M.;Karimov, Kh. S.
    • ETRI Journal
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    • v.27 no.3
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    • pp.319-325
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    • 2005
  • In this paper the effect of temperature on the electrical properties of organic semiconductor disperse orange dye 25 (OD) have been examined. Thin films of OD have been deposited on $In_{2}O_{3}$ substrates using a centrifugal machine. DC current-voltage (I-V) characteristics of the fabricated devices $(Al/OD/In_{2}O_{3)$ have been evaluated at varying temperatures ranging from 40 to $60^{\circ}C$. A rectification behavior in these devices has been observed such that the rectifying ratio increases as a function of temperature. I-V characteristics observed in $Al/OD/In_{2}O_{3)$ devices have been classified as low temperature $({\leq} 50^{\circ}C)$ and high temperature characteristics (approximately $60^{\circ}C$). Low temperature characteristics have been explained on the basis of the charge transport mechanism associated with free carriers available in OD, whereas high temperature characteristics have been explained on the basis of the trapped space-charge-limited current. Different electrical parameters such as traps factor, free carrier density, trapped carrier density, trap density of states, and effective mobility have been determined from the observed temperature dependent I-V characteristics. It has been shown that the traps factor, effective mobility, and free carrier density increase with increasing values of temperature, whilst no significant change has been observed in the trap density of states.

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Nutritional Quality of Dried Pig Placenta

  • Jang, Ae-Ra;Kim, Il-Joon;Lee, Moo-Ha;Jo, Cheo-Run
    • Preventive Nutrition and Food Science
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    • v.12 no.2
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    • pp.89-94
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    • 2007
  • Nutrients and hormone levels of dried pig placenta were studied. Placentas were freeze-dried (FD), oven-dried at 60 (OD-60), and 90$^{\circ}C$ (OD-90) and then crushed by a blender into small pieces. FD and OD-60 pig placenta had a higher moisture content than did OD-90, with no difference between FD and OD-60. There were no large differences in compositions of crude protein, crude fat, and crude ash of dried placenta among the treatments and the contents of K, Fe, and ${\alpha}$-tocopherol were highest in FD (p<0.05). Glutamine and glycine were the most abundant amino acids in all dried placenta and tyrosine was highly retained in FD placenta, compared with OD (p<0.05). Estradiol was the major sex hormone, followed by progesterone and testosterone in all dried placentas. Antibiotics including amoxicillin, sulfamethazine, tylosin, and chlorotetracyclin were not detected from the pig placentas tested. These results demonstrate that placenta is a good biomaterial with high nutritional quality, and that freeze drying is superior to oven drying for processing pig placenta.

The Effect of Openness to Diversity on Innovative Behavior: The Mediating Effect of Unit-members Trust (장병의 다양성 수용도가 혁신행동에 미치는 영향: 부대원 신뢰의 매개효과)

  • Jeon, Je-Man;Park, Chun-Seok;Moon, Sung-Ok
    • Asia-Pacific Journal of Business
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    • v.12 no.4
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    • pp.211-225
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    • 2021
  • Purpose - This study deals with the Openness to Diversity(OD) of soldiers in the military organization for efficient unit operation of the military organization composed of various soldier. The purpose of this study was to examine the effects of information and value OD on innovative behavior and the mediating effect of unit-members trust. Design/methodology/approach - The 269 samples of this study were surveyed on army soldiers. The Exploratory Factor Analysis (EFA), the multiple regression, bootstraping analysis were hired in order to analyze the data. Findings - The results showed that the information & value OD were positive(+) effect on innovative behavior. Unit-members trust showed a mediation effect between OD and innovative behavior. Research implications or Originality - First, according to Defense Reform 2.0, the military is expected to be composed of more diverse classes in the future. There is a theoretical contribution that examine their perception of diversity within the military. Second, OD was confirmed as a variable predicting the innovative behavior of soldiers and unit-memeber trust mediate the relationship between OD and invative behavior.

ELISA of rat sera infected with Paragonimus iloktsuenensis (이락촌폐흡충 감염 쥐의 혈청에 대한 효소면역 반응(ELISA))

  • Im, Byeong-Gil;Lee, Ok-Ran;Nam, Hae-Seon
    • Parasites, Hosts and Diseases
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    • v.28 no.4
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    • pp.207-212
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    • 1990
  • Enzyme-linked immunosorbent assay(ELISA) of paragonimiasis iloktsuenensis rat sera was performed using crude antigens of Paragonimus iloktsuenensis(PIA), P. westermani (PWA) and Clonorchis sinensis(CSA). Three crude antigens(PIA, PWA, CSA) were prepared to saline homogenated supernatants of whole adult worms. Infected rat sera were obtained biweekly from the albino rats fed 50∼.80 metacercariae of P. iloktsuenensis through gastric catheter. Experimental groups were divided into 4 groups: GI(controls), GII, GIII and GIV according to 1∼7 worms as GII, 10∼19 worms as GIII and 22∼40 worms as GIV, respectively, In ELISA, the mean OD values of each group for the homologous antigen(PIA) were increased significantly compared to the control sera at the 4th week of infection. With the progress of duration of infection, the mean OD values of infected sera of GII & GIV continuously increased up to the 12th week(last week), but in GIII the mean OD value increased until the loth week. No significance was noted among the infection dose groups (GII, GIII and GIV), after the 6th week of infection. Also, the OD values of all infected rats did not show any Proportional relytionships to the number of worms recovered. In brief, the antibody productivity of individual rats were strongly different. The rat sera infected with p. iloktsuenensis cross-reacted with those infected with P. westermani or C. sinensis, as identified by OD values.

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Anti-Proliferative Activity of OD78 Is Mediated through Cell Cycle Progression by Upregulation p27kip1 in Rat Aortic Vascular Smooth Muscle Cells

  • Tudev, Munkhtsetseg;Lim, Yong;Park, Eun-Seok;Kim, Won-Sik;Lim, Il-Ho;Kwak, Jae-Hwan;Jung, Jae-Kyung;Hong, Jin-Tae;Yoo, Hwan-Soo;Lee, Mi-Yea;Pyo, Myoung-Yun;Yun, Yeo-Pyo
    • Biomolecules & Therapeutics
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    • v.19 no.2
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    • pp.187-194
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    • 2011
  • Atherosclerosis and post-angiography restenosis are associated with intimal thickening and concomitant vascular smooth muscle cell (VSMC) proliferation. Obovatol, a major biphenolic component isolated from the Magnolia obovata leaf, is known to have anti-inflammatory and anti-tumor activities. The goal of the present study was to enhance the inhibitory effects of obovatol to improve its potential as a preventive or therapeutic agent in atherosclerosis and restenosis. Platelet-derived growth factor (PDGF)-BB-induced proliferation of rat aortic smooth muscle cells (RASMCs) was examined in the presence or absence of a newly synthesized obovatol derivative, OD78. The observed anti-proliferative effect of OD78 was further investigated by cell counting and [$^3H$]-thymidine incorporation assays. Treatment with 1-4 ${\mu}M$ OD78 dose-dependently inhibited the proliferation and DNA synthesis of 25 ng/ml PDGF-BB-stimulated RASMCs. Accordingly, OD78 blocked PDGF-BB-induced progression from the $G_0/G_1$ to S phase of the cell cycle in synchronized cells. OD78 decreased the expression levels of CDK4, cyclin E, and cyclin D1 proteins, as well as the phosphorylation of retinoblastoma protein and proliferating cell nuclear antigen; however, it did not change the CDK2 expression level. In addition, OD78 inhibited downregulation of the cyclin-dependent kinase inhibitor (CKI) $p27^{kip1}$. However, OD78 did not affect the CKI $p21^{cip1}$ or phosphorylation of early PDGF signaling pathway. These results suggest that OD78 may inhibit PDGF-BB-induced RASMC proliferation by perturbing cell cycle progression, potentially through $p27^{kip1}$ pathway activation. Consequently, OD78 may be developed as a potential anti-proliferative agent for the treatment of atherosclerosis and angioplasty restenosis.