• Title/Summary/Keyword: OC4

Search Result 611, Processing Time 0.135 seconds

Detection rate and clinical impact of respiratory viruses in children with Kawasaki disease

  • Kim, Ja Hye;Yu, Jeong Jin;Lee, Jina;Kim, Mi-Na;Ko, Hong Ki;Choi, Hyung Soon;Kim, Young-Hwue;Ko, Jae-Kon
    • Clinical and Experimental Pediatrics
    • /
    • v.55 no.12
    • /
    • pp.470-473
    • /
    • 2012
  • Purpose: The purpose of this prospective case-control study was to survey the detection rate of respiratory viruses in children with Kawasaki disease (KD) by using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR), and to investigate the clinical implications of the prevalence of respiratory viruses during the acute phase of KD. Methods: RT-PCR assays were carried out to screen for the presence of respiratory syncytial virus A and B, adenovirus, rhinovirus, parainfluenza viruses 1 to 4, influenza virus A and B, metapneumovirus, bocavirus, coronavirus OC43/229E and NL63, and enterovirus in nasopharyngeal secretions of 55 KD patients and 78 control subjects. Results: Virus detection rates in KD patients and control subjects were 32.7% and 30.8%, respectively (P=0.811). However, there was no significant association between the presence of any of the 15 viruses and the incidence of KD. Comparisons between the 18 patients with positive RT-PCR results and the other 37 KD patients revealed no significant differences in terms of clinical findings (including the prevalence of incomplete presentation of the disease) and coronary artery diameter. Conclusion: A positive RT-PCR for currently epidemic respiratory viruses should not be used as an evidence against the diagnosis of KD. These viruses were not associated with the incomplete presentation of KD and coronary artery dilatation.

OSTEOGENESIS BY BMP-2 IN ADULT STEM CELL DERIVED FROM BUCCAL FAT PAD (BMP-2에 의한 협부 지방 성체 줄기세포의 골형성)

  • Kim, Chang-Hyen;Park, Cheol-Hun;Lee, Il-Kyu;Pyo, Sung-Woon
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • v.34 no.4
    • /
    • pp.412-418
    • /
    • 2008
  • Bone morphogenetic proteins (BMPs) in combination with stem cells gain more significance for their use in bone tissue engineering. The mesenchymal stem cell can be differentiated into osteoblast by the treatment of BMP. The aim of this study is to characterize the osteogenic differentiation process of adult stem cells derived from buccal fat pad according to BMP-2 within culture media and decide the appropriate concentration of BMP-2 to facilitate osteogenesis. The authors procured the stem cell from buccal fat pad and analyzed for presence of stem cell by flow cytomety against CD-34, CD-105 and STRO-1. The buccal fat derived stem cells (BFDC) were treated by application of the different concentration with BMP-2 of 0, 10, 50, 100 and 200ng/ml, respectively. And their ability to differentiate into osteogenic pathway were checked by alkaline phosphatase(ALP) staining, Alizarin red staining and RT-PCR for osteocalcin(OC) gene expression at 7, 14 and 21day of culture. Flow cytometric analysis and biochemical assays demonstrated that BFDC might be a distinguished stem cells, and mineralization was accompanied in proportion to BMP-2 concentration. However, with 100ng/ml concentration of BMP-2, the BFDC demonstrated most efficient staining pattern of ALP and Alizarin red. The feasibility of the osteogenic differentiation in the group of both 50ng/ml and 200ng/ml of BMP-2 showed similar activity and relatively weaker than that of 100ng/ml. These results suggest that the BMP-2 stimulate osteogenesis by BFDC effectively and that bone induction might be controlled through negative regulatory feedback in higher concentration.

Pressure Effect on the Aquation of trans-[Cr$(en)_2Br_2]^+$ and trans-$[Cr(tn)_2Br_2]+^$ Ions (trans-[Cr$(en)_2Br_2]^+$ 및 trans-$[Cr(tn)_2Br_2]+^$ 착이온의 수화반응에 미치는 압력의 영향)

  • Jong Jae Chung;Park Kyung Suk
    • Journal of the Korean Chemical Society
    • /
    • v.30 no.4
    • /
    • pp.341-344
    • /
    • 1986
  • The rate for the aquation of trans-[Cr$(en)_2Br_2]^+$ and trans-$[Cr(tn)_2Br_2]+^$ ions in the aqueous solution has been measured by the conductometric method at various pressures and temperatures. The rate constants are increased with increasing temperature and decreased with increasing pressure. Activation volumes are all positive values and lie in the limited range +1.6 ∼ +2.3Oc$m^3$/mole for trans-[Cr$(en)_2Br_2]^+$ and +1.30 ∼ +1.92c$m^3$/mole for trans-$[Cr(tn)_2Br_2]+^$. Activation entropies have small negative values while activation compressibilities have small positive values. From the above results, we may deduce that the mechanism for the aquation of these complexes is the $I_d$ mechanism.

  • PDF

Strength Characteristics of Epoxy Resin Mortar (에폭시 수지 모르터의 강도 특성)

  • 정규석;강신업
    • Magazine of the Korean Society of Agricultural Engineers
    • /
    • v.24 no.3
    • /
    • pp.92-99
    • /
    • 1982
  • The objective of this study was to investigate the compressive and bending strength characteristics of epoxy resin mortar, which is still in an early stage of its use and study in Korea. The results obtained are summarized as follows; 1. The compressive strengths of epoxy resin mortar after 1 day, 2 days and 3 days were gained 87%, 91% and 95%, respectively, in view of that of mortar at the age of 7 days. This result showed that the initial compressive strength within 1 day was very high. 2. The highest compressive strength of epoxy resin mortar was 914 kg/cm2 at the point of having the mixing ratio of one to two. It reached up to 3.7 times that of the normal portland cement mortar at the age of 28 days. 3. The bending strengths of epoxy resin mortar after 1 day, 2 days and 3 days came up to 88%, 93% and 97%, respectively, in comparing that of mortar at the age of 7 days. It was expressed to be simielar to the tendency of compressive strength. 4. The highest bending strength of epoxy resin mortar was 384 kg/cm2 at mixing ratio of one to two. It came up to as much as 6.5 times in comparing with that of the normal portland cement mortar at the age of 28 days. Therefore, the epoxy resin mortar would be effective for promoting the bending strength of structural members. 5. The regression equation between compressive and bending strength was obtained as follows; oo~=0.391 oc+27.54 (r=0.99) And the estimated value of bending strength was corresponded to about 44 per cent in comparing with that of the compressive strength.

  • PDF

Bandgap Engineering in CZTSSe Thin Films via Controlling S/(S+Se) Ratio

  • Vijay C. Karade;Jun Sung Jang;Kuldeep Singh, Gour;Yeonwoo Park;Hyeonwook, Park;Jin Hyeok Kim;Jae Ho Yun
    • Current Photovoltaic Research
    • /
    • v.11 no.3
    • /
    • pp.67-74
    • /
    • 2023
  • The earth-abundant element-based Cu2ZnSn(S,Se)4 (CZTSSe) thin film solar cells (TFSCs) have attracted greater attention in the photovoltaic (PV) community due to their rapid development in device power conversion efficiency (PCE) >13%. In the present work, we demonstrated the fine-tuning of the bandgap in the CZTSSe TFSCs by altering the sulfur (S) to the selenium (Se) chalcogenide ratio. To achieve this, the CZTSSe absorber layers are fabricated with different S/(S+Se) ratios from 0.02 to 0.08 of their weight percentage. Further compositional, morphological, and optoelectronic properties are studied using various characterization techniques. It is observed that the change in the S/(S+Se) ratios has minimal impact on the overall Cu/(Zn+Sn) composition ratio. In contrast, the S and Se content within the CZTSSe absorber layer gets altered with a change in the S/(S+Se) ratio. It also influences the overall absorber quality and gets worse at higher S/(S+Se). Furthermore, the device performance evaluated for similar CZTSSe TFSCs showed a linear increase and decrease in the open circuit voltage (Voc) and short circuit current density (Jsc) of the device with an increasing S/(S+Se) ratio. The external quantum efficiency (EQE) measured also exhibited a linear blue shift in absorption edge, increasing the bandgap from 1.056 eV to 1.228 eV, respectively.

Review of the Silicon Oxide and Polysilicon Layer as the Passivated Contacts for TOPCon Solar Cells

  • Mengmeng Chu;Muhammad Quddamah Khokhar;Hasnain Yousuf;Xinyi Fan;Seungyong Han;Youngkuk Kim;Suresh Kumar Dhungel;Junsin Yi
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.36 no.3
    • /
    • pp.233-240
    • /
    • 2023
  • p-type Tunnel Oxide Passivating Contacts (TOPCon) solar cell is fabricated with a poly-Si/SiOx structure. It simultaneously achieves surface passivation and enhances the carriers' selective collection, which is a promising technology for conventional solar cells. The quality of passivation is depended on the quality of the tunnel oxide layer at the interface with the c-Si wafer, which is affected by the bond of SiO formed during the subsequent annealing process. The highest cell efficiency reported to date for the laboratory scale has increased to 26.1%, fabricated by the Institute for Solar Energy Research. The cells used a p-type float zone silicon with an interdigitated back contact (IBC) structure that fabricates poly-Si and SiOx layer achieves the highest implied open-circuit voltage (iVoc) is 750 mV, and the highest level of edge passivation is 40%. This review presents an overview of p-type TOPCon technologies, including the ultra-thin silicon oxide layer (SiOx) and poly-silicon layer (poly-Si), as well as the advancement of the SiOx and poly-Si layers. Subsequently, the limitations of improving efficiency are discussed in detail. Consequently, it is expected to provide a basis for the simplification of industrial mass production.

A Study on Chemical Characteristics of Aerosol Composition at West Inflow Regions in the Korean Peninsula II. Characteristics of Inorganic Aerosol Acidity and Organic Aerosol Oxidation (한반도 서부유입권역에서 대기 중 에어로졸 성분의 화학적 특성 연구 II. 입자의 산성도 및 산화 특성)

  • Choi, Jin-Soo;Kim, Jeong-Ho;Lee, Tae-Hyoung;Choi, Yong-Joo;Park, Tae-Hyun;Ahn, Joon-Young;Park, Jin-Soo;Kim, Hyun-Jae;Koo, Youn-Seo;Kim, Shin-Do;Hong, You-Deog;Hong, Ji-Hyung
    • Journal of Korean Society for Atmospheric Environment
    • /
    • v.32 no.5
    • /
    • pp.485-500
    • /
    • 2016
  • We examined acidity state of inorganic aerosol and oxidation state of organic aerosol by High Resolution Time of Flight Aerosol Mass Spectrometer (HR-ToF-AMS) at Baengnyeong Super site from Jan 2012 to Dec 2013. Additionally, we carried out the analysis for the aerosol component group of organic matter ($C_xH_y$, $C_xH_yO_1$, $C_xH_yO_z$, $C_xH_yO_zN_p$) and elemental composition to calculate H/C, O/C, N/C, OM/OC and identify the oxidation state. The aerosol chemical composition in this study is dominated by sulfate ($SO_4{^{2-}}$), nitrate ($NO_3{^-}$) plays a smaller role in aerosol acidity. Ammonium ($NH_4{^+}$) was found in a formation of $(NH_4)_3H(SO_4)_2$. However, the binding formations of $NH_4NO_3$ and $NH_4Cl$ increase in the winter. $C_xH_yO_1$ indicating the oxidized state of $PM_{1.0}$ has the highest ratio of 41% while $C_xH_y$ indicating the non-oxidized state has a lower ratio of 36%, meaning that the oxidation level of $PM_{1.0}$ in Baengnyeong Island is high. The ratio between H/C and O/C was 1.33 and 0.78 respectively, showing the characteristic of LV-OOA (Low volatility-Oxygenated Organic Aerosol). Acidic and oxidized aerosols sampled during this field study were largely anthropogenic in origin from Chinese continent and photochemically aged.

Analysis of Piled Raft Interactions on Clay with Centrifuge Test (원심모형실험을 통한 점토지반에서의 말뚝지지 전면기초 상호작용)

  • Park, Dong-Gyu;Choi, Kyu-Jin;Lee, Jun-Hwan
    • Journal of the Korean Geotechnical Society
    • /
    • v.28 no.9
    • /
    • pp.57-67
    • /
    • 2012
  • In the design for piled rafts, the load capacity of the raft is in general ignored and the load capacities of pile are only considered for the estimation of the total load carrying capacity of the piled raft. The axial resistance of piled raft is offered by the raft and group piles acting on the same supporting ground soils. As a consequence, pile - soil - raft and pile - soil interactions, occurring by stress and displacement duplication with pile and raft loading conditions, acts as a key element in the design for piled rafts. In this study, a series of centrifuge model tests has been performed to compare the axial behavior of group pile and raft with that of a piled raft (having 16 component piles with an array of $4{\times}4$) at the stiff and soft clays. From the test results, it is observed that the interactions of piles, soil, and raft has little influences on the load capacities of piles and raft in piled rafts compared with the load capacities of group piles and raft at the same clay soil condition.

Metamorphic Evolution of the central Ogcheon Metamorphic Belt in the Cheongju-Miwon area, Korea (청주-미원지역 중부 옥천변성대의 변성진화과정)

  • 오창환;권용완;김성원
    • The Journal of the Petrological Society of Korea
    • /
    • v.8 no.2
    • /
    • pp.106-124
    • /
    • 1999
  • In the Cheongju-Minwon area which occupies the middle part of the Ogcheon Metamorphic Belt, three metamorphic events(M1, M2, M3) had occurred. Intermediate P/T type M2 regional metamorphism formed prevailing mineral assemblages in the study area. Low PIT type M3 contact metamorphism occurred due to the intrusion of granites after M2 metamorphism. M1 metamorphism is recognized by inclusions within garnet. During M2 metamorphism, the metamorphic grade increased from the biotite zone in the southeastern part to the garnet zone in the northwestern part of the study area. This result is similar to the metamorphic evolution of the southwestern part of the Ogcheon Metamorphic Belt. Garnets in the garnet zone are classified into two types; Type A garnet has inclusions whose trail is connected to the foliation in the matrix and Type B garnet has inclusion rich core and inclusion poor rim. Type A garnet formed in the mica rich part with crenulation cleavage whereas Type B garnet formed in the quartz rich part with weak crenulation cleavage. In some outcrops, two types garnets are found together. Compared to the rim of Type A garnet, the rim of Type B garnet is lower in grossular and spessartine contents but higher in almandine and pyrope contents. In some Type B garnets, the inclusion poor part is rimmed by muddy colored or protuberant new overgrowth. In the inclusion poor part and new overgrowth, a rapid increase in grossular and decrease in spessartine is observed. However, the compositional patterns of Type A and B are similar; Ca increases and Mn decreases from core to rim. Two types garnets formed mainly due to the difference of bulk chemistry instead of metamorphic and deformational differences. The metamorphic P-T conditions estimated from Type A garnets are 595-690 OC15.7-8.8 kb, which indicates M2 metamorphism is intermediate P/T type metamorphism. On the other hand, a wide range of P-T conditions is calculated from Type B garnets. The P-T conditions from most Type B garnet rims are 617-690 OC16.2-8.9 kb which also indicates an intermediate P/T type metamorphism. However, at the rim part with flat end or weak overgrowth, grossular content is low and 573-624OC14.7-5.8 kb are estimated. The P-T conditions calculated from plagioclase and biotite inclusions in garnet are 460-500 0C/1.9-3.0 kb. The P-T conditions from rim part with weak overgrowth and inclusions within garnet, indicate that low P/T type M1 regional metamorphism might have occurred before intermediate P/T type M2 regional metamorphism. The P-T conditions estimated from samples which had undergone low PIT type M3 metamorphism strongly, are 547-610 0C/2.1-5.0 kb.

  • PDF

Association between Respiratory Virus Infection and Pneumococcal Colonization in Children (소아에서의 호흡기바이러스 감염과 비인두 폐렴구균 보균의 연관성)

  • Lee, Hyeon Seung;Choe, Young June;Cho, Eun Young;Lee, Hyunju;Choi, Eun Hwa;Lee, Hoan Jong
    • Pediatric Infection and Vaccine
    • /
    • v.21 no.3
    • /
    • pp.207-213
    • /
    • 2014
  • Purpose: This study aimed to investigate the association between respiratory virus infection and pneumococcal colonization in children. Methods: From May 2009 to June 2010, nasopharyngeal (NP) aspirates were obtained from patients under 18 years old who visited Seoul National University Children's Hospital for respiratory symptoms. NP samples were used to detect respiratory viruses (influenza virus A and B, parainfluenza virus 1, 2 and 3, respiratory syncytial virus A and B, adenovirus, rhinovirus A/B, human metapneumovirus, human coronavirus 229E/NL63 and OC43/HKU1) by RT-PCR and pneumococcus by culture. Results: Median age of the patients was 27 months old. A total of 1,367 NP aspirates were tested for respiratory viruses and pneumococcus. Pneumococcus was isolated from 228 (16.7%) of samples and respiratory viruses were detected from 731 (53.5%). Common viruses were rhinovirus (18.4%), respiratory syncytial virus (RSV) A (10.6%), adenovirus (6.9%), influenza virus A (6.8%). Pneumococcal isolation rate was significantly higher in the cases of positive virus detection than negative detection [21.3% (156/731) vs. 11.3% (72/636), P <0.001]. For individual viruses, pneumococcal isolation rate was positively associated with detection of influenza virus A [24.7% (23/93) vs 16.1% (205/1274), P=0.001], RSV A [28.3% (41/145) vs 15.3% (187/1222), P=0.001], RSV B [31.3% (10/32) vs 16.3% (218/1335), P=0.042], rhinovirus A/B [22.6% (57/252) vs 15.3% (171/1115), P=0.010]. Conclusion: The study revealed that pneumococcal isolation from NP aspirates is related with respiratory virus detection. The result of this study could be used to investigate how respiratory viruses and pneumococcus cause clinical diseases.