• BMB Reports
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• v.40 no.6
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• pp.899-910
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• 2007

Extracellular Regulated Kinases (ERK) and Protein Kinase B (Akt) are intermediaries in relaying extracellular growth signals to intracellular targets. Each pathway can become activated upon stimulation of G protein-coupled receptors mediated by $G_q$ and $G_{i/o}$ proteins subjected to regulation by RGS proteins. The goal of the study was to delineate the specificity in which cardiac RGS proteins modulate $G_{q^-}$ and $G_{i/o}$-induced ERK and Akt phosphorylation. To isolate $G_{q^-}$ and $G_{i/o}$-mediated effects, we exclusively expressed muscarinic $M_2$ or $M_3$ receptors in COS-7 cells. Western blot analyses demonstrated increase of phosphorylation of ERK 1.7-/3.3-fold and Akt 2.4-/6-fold in $M_{2^-}/M_{3^-}$ expressing cells through carbachol stimulation. In co-expressions, $M_3/G_q$-induced activation of Akt was exclusively blunted through RGS3s/RGS3, whereas activation of ERK was inhibited additionally through RGS2/RGS5. $M_2/G_{i/o}$ induced Akt activation was inhibited by all RGS proteins tested. RGS2 had no effect on $M_2/G_{i/o}$-induced ERK activation. The high degree of specificity in RGS proteins-depending modulation of $G_{q^-}$ and $G_{i/o}$-mediated ERK and Akt activation in the muscarinic network cannot merely be attributed exclusively to RGS protein selectivity towards $G_q$ or $G_{i/o}$ proteins. Counter-regulatory mechanisms and inter-signaling cross-talk may alter the sensitivity of GPCR-induced ERK and Akt activation to RGS protein regulation.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2003.11b
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• pp.295-299
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• 2003

1. 고정화 $TiO_2$의 경우도 분말을 이용한 것과 같이 최적 광촉매 투입량이 나타났으며, 최적 투입량은 33.8 g/L이었고, 분말 $TiO_2$를 이용한 경우보다 빠른 초기반응속도를 보였으며, 최종반응시간도 빠른 것으로 나타났다. 2. 수용액에서 빠른 초기 제거속도의 1차적인 기작은 고정화 $TiO_2$ 표면으로의 흡착 때문이었으며, 빠른 흡착으로 인해 수용액 중의 RhB 농도가 빠르게 감소하여 광 투과율이 증가하므로 전체 반옹속도가 빠른 것으로 사료되었다. 3. 고정화 $TiO_2$를 이용한 유동층 반응기의 경우 최적 공기 공급량은 의한 Rhodamine B의 초기 제거속도는 분말보다 빠르지만 전체적인 제거시간은 흡착된 Rhodamine B의 분해 때문에 분말 $TiO_2$보다 느린 것으로 나타났다.

• Journal of the Korean Mathematical Society
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• v.51 no.4
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• pp.655-663
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• 2014

Let R be a ring with identity, X(R) the set of all nonzero, non-units of R and G(R) the group of all units of R. We show that for a matrix ring $M_n(D)$, $n{\geq}2$, if a, b are singular matrices of the same rank, then ${\mid}o_{\ell}(a){\mid}={\mid}o_{\ell}(b){\mid}$, where $o_{\ell}(a)$ and $o_{\ell}(b)$ are the orbits of a and b, respectively, under the left regular action. We also show that for a semisimple Artinian ring R such that $X(R){\neq}{\emptyset}$, $$R{{\sim_=}}{\oplus}^m_{i=1}M_n_i(D_i)$$, with $D_i$ infinite division rings of the same cardinalities or R is isomorphic to the ring of $2{\times}2$ matrices over a finite field if and only if ${\mid}o_{\ell}(x){\mid}={\mid}o_{\ell}(y){\mid}$ for all $x,y{\in}X(R)$.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2008.11a
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• pp.439-440
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• 2008

• 한국초전도학회:학술대회논문집
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• 2008.08a
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• pp.92-92
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• 2008

• Imaging Science in Dentistry
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• v.31 no.1
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• pp.1-7
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• 2001

Purpose : To evaluate the usefulness of the reconstructed 3-dimensional image on the personal computer in comparison with that of the CT workstation by quantitative comparison and analysis. Materials and Methods : The spiral CT data obtained from 27 persons were transferred from the CT workstation to a personal computer, and they were reconstructed as 3-dimensional image on the personal computer using V-works 2.0/sup TM/. One observer obtained the 14 measurements on the reconstructed 3-dimensional image on both the CT workstation and the personal computer. Paired Nest was used to evaluate the intraobserver difference and the mean value of the each measurement on the CT workstation and the personal computer. Pearson correlation analysis and % incongruence were also performed. Results: I-Gn, N-Gn, N-A, N-Ns, B-A, and G-Op did not show any statistically significant difference (p>0.05), B-O, B-N, Eu-Eu, Zy-Zy, Biw, D-D, Orbrd R, and L had statistically significant difference (p<0.05), but the mean values of the differences of all measurements were below 2 mm, except for D-D. The value of correlation coefficient y was greater than 0.95 at I-Gn, N-Gn, N-A, N-Ns, B-A, B-N, G-Op, Eu-Eu, Zy-Zy, and Biw, and it was 0.75 at B-O, 0.78 at D-D, and 0.82 at both Orbrd Rand L. The % incongruence was below 4% at I-Gn, N-Gn, N-A, N-Ns, B-A, B-N, G-Op, Eu-Eu, Zy-Zy, and Biw, and 7.18%, 10.78%, 4.97%, 5.89% at B-O, D-D, Orbrd Rand L respectively. Conclusion : It can be considered that the utilization of the personal computer has great usefulness in reconstruction of the 3-dimensional image when it comes to the economics, accessibility and convenience, except for thin bones and the landmarks which are difficult to be located.

• Korean Chemical Engineering Research
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• v.59 no.4
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• pp.611-625
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• 2021

Mg crowns were manufactured using domestic dolomite (Ca·Mg(CO₃)₂) (20~30 mm). In order to manufacture the calcined dolomite (CaO·MgO), (a) electric furnace (950 ℃, 480 min) and (b) microwave furnace (950 ℃, 60 min) processes were used. As a result of XRD analysis, it was analyzed as (a) CaO 56.9 wt%, MgO 43.1 wt% by electric furnace process and (b) CaO 55 wt%, MgO 45 wt% by microwave furnace process. Even when the decarbonation reaction time of dolomite was shortened by 1/8 in microwave furnace process compare with electric furnace process, the calcined dolomite could be produced. The hydration reaction (ASTM C 110) is a standard for the hydration reactivity of calcined dolomite, and the calcined dolomite produced by electric furnace process showed a high hydration reactivity (max temp 79.8 ℃/1.5 minutes). Such hydration reactivity was occurred by only CaO hydration reaction and that was confirmed by XRD analysis. The calcined dolomite produced by microwave furnace process showed low hydration reactivity (max temp 81.7 ℃/19.5 minutes). Such low hydration reactivity was occurred by CaO and MgO hydration reaction due to the hydration reaction of CaO thereafter occurring of the hydration reaction of MgO, and that was confirmed by XRD analysis. The prepared Mg crown were 58.8 g and 74.6 g by electric furnace and microwave furnace processes, respectively, under the reaction conditions of 1,230 ℃, 60 min, 5 × 10^-2 torr by silicothermic reduction.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2008.11a
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• pp.452-457
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• 2008

분말 TiO$_2$를 코팅한 전극은 전기저항으로 인해 0.5 A 이상의 전류를 인가할 수 없었으며, 1 A를 적용하였을 때 60분의 반응시간 후 최종 RhB 농도를 측정한 결과 Ru/Ti 전극의 RhB 농도 감소 가장 큰 것으로 나타났고, Ru/Ti > Ti > SG-TiO$_2$ > Th-TiO$_2$로 나타났다. 전기분해 공정만 적용한 경우 RhB 농도 감소의 순서는 Ru/Ti = Ti > SG-TiO$_2$ > Th-TiO$_2$ 전극의 순서로 나타났다. UV만 적용한 경우 RhB 제거는 작았으며, Ti와 Ru/Ti 전극은 UV만 적용한 경우와 RhB 제거농도가 비슷하였는데 이는 전극 표면에서 광촉매 반응이 일어나지 않는다는 것을 의미한다. 반면 TiO$_2$를 전극 표면에 형성하거나 코팅한 전극은 UV만 적용한 경우보다 RhB 농도가 낮게 나타났고, TiO$_2$가 형성되거나 코팅된 전극은 P-TiO$_2$ > Th-TiO$_2$ > SG-TiO$_2$의 순서로 나타났으나 차이는 크지 않았다. 광전기촉매 공정에서 시너지 효과가 거의 없는 것은 전극 표면에 코팅되거나 형성된 TiO$_2$의 양이 적고 광촉매 반응에 의한 분해 정도가 낮아 전자-정공의 재결합 감소효과가 적기 때문인 것으로 사료되었다. Th-TiO$_2$와 SG-TiO$_2$ 전극의 경우 전해질로 Na$_2$SO$_4$를 사용한 경우의 RhB 농도가 NaCl을 사용한 경우보다 RhB 낮게 나타났으나, Ti와 Ru/Ti 전극의 경우는 반대 현상이 나타났다. 이와 같은 결과는 광촉매 반응이 높은 Th-TiO$_2$와 SG-TiO$_2$ 전극에서의 Cl$^-$의 광촉매 반응 저해현상이 높게 나타났기 때문이라고 사료되었다. 반면 DSA 전극인 Ti와 Ru/Ti 전극의 경우 광촉매 반응이 거의 나타나지 않기 때문에 주반응인 전기분해 반응에서의 촉진 반응이 지배적이기 때문에 Th-TiO$_2$와 SG-TiO$_2$ 전극과는 정 반대의 현상이 나타났다고 사료되었다. 전기/UV 공정에서는 최적 전류는 0.75 A, NaCl 투입량은 0.5 g/L로 나타났으며, 최적 UV램프 전력은 16 W인 것으로 나타났다.

• Journal of the Korea Institute of Building Construction
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• v.12 no.1
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• pp.54-63
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• 2012

The purpose of this study is to examine the potential for reducing the environmental load and $CO_2$ gas when cement is produced by using cement substitutes. These substitutes consisted of blast furnace slag, red mud and silica fume, which were industrial by-products. The most optimum mix was derived when alkali accelerator was added to low carbon inorganic composite mixed with industrial by-product at room temperature. It is determined that hardened properties and the results of compressive strength tests changed based on CaO content, Si/Al, the mixing ratio and the amount of alkali accelerator, curing conditions and W/B. The results of test analysis suggest that the optimum mix of low carbon inorganic composite is CaO content 30%, Si/Al 4, the mixed ratio of alkali accelerator $(NaOH:Na_2SiO_3)$ 50g:50g, the amount of alkali accelerator 100g and W/B 31%. In addition, if contraction is complemented, low carbon inorganic composite with superior performance could be developed.

• Electrical & Electronic Materials
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• v.10 no.6
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• pp.533-540
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• 1997

The microwave dielectric properties of ((P $b_{1-x}$ C $a_{x}$)Zr $O_3$ and (P $b_{0.63}$,C $a_{0.37-x}$ $M_{x}$)Zr $O_3$(M=Mg,Sr) ceramics were investigated. In (P $b_{1-x}$ C $a_{x}$)Zr $O_3$ (X=0.33~0.40) ceramics, high quality factor and small temperature coefficient of resonant frequency were obtain in (P $b_{0.63}$C $a_{0.37}$)Zr $O_3$with perovskite structure. In the case of (P $b_{0.63}$C $a_{0.37-x}$M $g_{x}$)Zr $O_3$ dielectric constant temperature coefficient of resonant frequency increased and quality factor decreased due to increase of polarization of A-O bonding. When replacing Ca ion with Sr ion with large ion radius, polarization decreased with increased of bonding length and thus dielectric constant and temperature coefficient of resonant frequency decreased.decreased.creased.