• Korean Journal of Exercise Nutrition
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• v.15 no.4
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• pp.173-182
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• 2011

Post-traumatic stress disorder (PTSD) is a stress-related mental disorder induced by severe external stressors such as assault, disaster or severe accident. We investigated the effects of treadmill exercise on short-term memory in relation to apoptosis and cell proliferation in the hippocampus following PTSD. Stress to the pregnant rats was induced by exposure of maternal rats to the hunting dog in an enclosed room. Exposure time was 10 min, repeated three times per day, with 1 hour interval. Exposure of maternal rats to the hunting dog was continued 7 days after pregnancy until delivery. The pregnant rats in the exercise groups were forced to run on a treadmill for 30 min once a day for the same duration of stress exposure. Step-down avoidance task for short-term memory, western blot for Bcl-2, Bax, and immunohistochemistry for caspase-3, 5-bromo-2'-deoxyuridine (BrdU), and Ki-67 were conducted. Maternal rats exposed to stress during pregnancy showed short-term memory impairment. Expressions of Bax, Bcl-2, ratio of Bax to Bcl-2, and caspase-3 in the hippocampus were increased in the PTSD rats. Cell proliferation in the hippocampal dentate gyrus was decreased in the PTSD rats. Treadmill exercise alleviated short-term memory impairment and suppressed expressions of Bax, the ratio of Bax to Bcl-2, and caspase-3. Treadmill exercise also increased cell proliferation. The present results indicate that treadmill exercise alleviated PTSD-induced short-term memory impairment by suppressing apoptotic cell death and enhancing cell proliferation in the hippocampus.

• Safety and Health at Work
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• v.14 no.3
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• pp.267-271
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• 2023

Background: The objective of this study is to identify the working conditions and health status of Vietnamese male migrant workers in Republic of Korea, in comparison to the Korean general population. Methods: We conducted our survey through the Migrant People Center, and we received completed questionnaires from 87 male Vietnamese migrant workers. The questionnaire employed was identical to those used in the Korean Working Conditions Survey and the 2020 Korea National Health and Nutrition Examination Survey. The collected data from the Vietnamese migrant workers was then compared with the Korean reference population using indirect age-standardization. Results: Vietnamese male workers demonstrated a higher prevalence of health problems including hearing problems (age-standardized prevalence ratio (aSPR) 13.22, 95% confidence interval [CI]: 8.07-20.4), skin problems (aSPR 13.49, 95% CI: 8.07-20.4), and low back pain (aSPR 8.40, 95% CI: 6.50-10.69). Elevated exposure to workplace hazards such as chemicals (aSPR 2.36, 95% CI: 1.51-3.51), organic solvents (aSPR 2.22, 95% CI: 1.44-3.28), handling of heavy objects (aSPR 1.67, 95% CI: 1.24-2.21), and high temperatures (aSPR 1.96, 95% CI: 1.46-2.57) was observed among them. Additionally, they faced a higher risk of no personal protective equipment (aSPR 2.53, 95% CI: 1.26-4.52) and a greater prevalence of unmet medical needs (aSPR 7.14, 95% CI: 4.74-10.32). Conclusion: Our findings highlight the elevated workplace hazards, health problems, and unmet medical needs among Vietnamese male workers compared to the Korean reference population. These findings underscores the urgency for enhanced scrutiny over working conditions and protective equipment provision, coupled with efforts to improve healthcare accessibility and worker education.

• Animal Bioscience
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• v.37 no.1
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• pp.116-122
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• 2024

Objective: This research was conducted to evaluate the effects of citrus fiber (CF) as a natural alternative to sodium tripolyphosphate (STPP) in marinated broiler boneless chicken breast and inside beef skirt on overall retention rate, shear force, and consumer sensory attributes. Methods: Five different marinade formulations were targeted to include 0.9% salt, either 0.25% or 0.50% STPP or CF and water on a finished product basis. Water and salt only were considered the negative control (CON). Chicken breasts (n = 14) and inside beef skirt (n = 14) were randomly assigned to a treatment, raw weights recorded and then placed in a vacuum tumbler. Marinated weights were recorded, individually packed, and randomly assigned to either retail display for 10-day retention rate, shear force analysis, cook loss, or consumer sensory panel. Results: Pickup percentage, and overall retention was similar among treatments for chicken breast and inside beef skirt. Citrus fiber treatments resulted in higher cooking loss compared to the CON in chicken breast; though, CF050 resulted in similar cooking loss compared to STPP025 in inside beef skirt. No differences were found in sensory attributes for chicken breast, however, WBSF data showed CF025 was tougher than CF050, STPP050, and CON. Inside beef skirt with CF050 were least liked overall by the consumer panel. Conclusion: Citrus fiber included in marinades at a lower percentage rate can produce similar texture characteristics, and sensory properties compared with those marinated with STPP.

• Journal of the Korean Applied Science and Technology
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• v.40 no.4
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• pp.890-896
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• 2023

This study aims to examine the relationship between serum folic acid levels and metabolic syndrome. The analysis data were downloaded and used for the 7th 3rd (2018) data of the National Health and Nutrition Survey and in this study, 495 men, 706 women, and a total of 1,201 people were finally analyzed. The data analysis used Chi-square and t-test for the difference in serum folic acid according to general characteristics, Pearson correlation for the relationship between sub-factors of metabolic syndrome, and logistic regression analysis for serum folic acid levels and metabolic syndrome indicators. According to the results of this study, there was a significant negative correlation between serum folic acid levels and waist circumference (r=-0.113, p<0.01), triglyceride (r=-0.086, p<0.05), and HDL-cholesterol (r=0.086, p<0.05) showed a significant positive correlation. As a result of regression analysis, in the case of HDL-cholesterol, the group with normal serum folic acid levels was significantly higher than the group with low (p<0.05). Therefore, through this study, it is proposed to develop appropriate eating habits and health education programs to prevent metabolic syndrome.

• BMB Reports
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• v.57 no.2
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• pp.98-103
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• 2024

The mammalian sirtuin family (SIRT1-SIRT7) has shown diverse biological roles in the regulation and maintenance of genome stability under genotoxic stress. SIRT7, one of the least studied sirtuin, has been demonstrated to be a key factor for DNA damage response (DDR). However, conflicting results have proposed that Sirt7 is an oncogenic factor to promote transformation in cancer cells. To address this inconsistency, we investigated properties of SIRT7 in hepatocellular carcinoma (HCC) regulation under DNA damage and found that loss of hepatic Sirt7 accelerated HCC progression. Specifically, the number, size, and volume of hepatic tumor colonies in diethylnitrosamine (DEN) injected Sirt7-deficient liver were markedly enhanced. Further, levels of HCC progression markers and pro-inflammatory cytokines were significantly elevated in the absence of hepatic Sirt7, unlike those in the control. In chromatin, SIRT7 was stabilized and colocalized to damage site by inhibiting the induction of γH2AX under DNA damage. Together, our findings suggest that SIRT7 is a crucial factor for DNA damage repair and that hepatic loss-of-Sirt7 can promote genomic instability and accelerate HCC development, unlike early studies describing that Sirt7 is an oncogenic factor.

• The Journal of the Convergence on Culture Technology
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• v.10 no.3
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• pp.121-130
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• 2024

This study utilized data from 1,068 women aged 40-59, drawn from the 8th Korea National Health and Nutrition Examination Survey (KNHANES) conducted in 2020, to investigate factors impacting subjective health perception and health-related quality of life. Methodologically, STATA 15.0 was employed for complex sample mean and standard deviation calculations, complex sample weighted percentages, complex sample t-tests, and multiple regression analyses. Common factors influencing both subjective health and health-related quality of life included education level, household size, depression, and stress. Age, binge drinking, and physical activity were identified as factors influencing subjective health perception. Insurance type, employment status, and sleep disorders emerged as factors impacting health-related quality of life. Recognizing middle age as a crucial transitional phase into old age, the development of health policy programs aimed at enhancing subjective health and health-related quality of life during this period is deemed essential.

• Journal of the Korean Society of Physical Medicine
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• v.19 no.1
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• pp.23-30
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• 2024

PURPOSE: The purpose of this study is to identify the incidence of chronic obstructive pulmonary disease (COPD) and risk factors for diseases in adults over 40 years of age in Korea, and to provide basic data for the prevention of COPD incidence through management. METHODS: Based on the 2019 data of the Korea National Health and Nutrition Examination Survey (KNHANES), 1,788 adults over the age of 40 who participated in pulmonary function test and health survey were selected as subjects. COPD incidence risk factors were analyzed using complex sample multiple logistic regression analysis. RESULTS: As a result of the analysis, the incidence of COPD in Korea was 11.5%, and the risk of developing COPD was higher in men, age, and current smokers. Compared to women, men had an increased risk of developing COPD by 2.369 times (95% CI 1.289-4.355). In age, the risk of COPD incidence increased by 3.702-fold (95% CI 1.923-7.124) in their 50s, 11.238-fold (95% CI 6.009-21.017) in their 60s, and 28.320-fold (95% CI 14.328-55.977) in their 70s compared to those in their 40s. In the smoking state, 2.302 times (95% CI 1.373-3.860) of past smokers and 4.542 times (95% CI 2.694-7.658) of current smokers were found to have a higher risk of developing COPD than non-smokers. CONCLUSION: To reduce the incidence of COPD, interventions are required to prevent disease development through lifestyle and smoking cessation education in subjects with COPD risk factors.

• Journal of Advanced Technology Convergence
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• v.3 no.2
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• pp.1-7
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• 2024

This study was conducted on 2,380 people aged 40-64 years old among the subjects of the National Health and Nutrition Examination Survey in 2021, the 3rd year of the 8th period. In order to identify factors influencing disease morbidity and health-related quality of life according to household type, general characteristics, diseases, etc. Morbidity and physical factors were compared and analyzed. The data were analyzed after creating a weighted complex sample plan file using the spss 25.0 program, and the significance level was set at .05. As a result of the analysis, factors affecting single-person households were education level, restrictions of activity, and depression, and factors affecting multi-person households were gender, smoking, restrictions of activity, dyslipidemia, and depression. Subjective health status showed a positive correlation with health-related quality of life, and anxiety and stress showed a negative correlation. Based on the results of this study, It is that propose individual quality-of-life improvement interventions that take into account each influencing factor for each household type.

• Journal of agricultural medicine and community health
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• v.49 no.2
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• pp.93-101
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• 2024

Objective: This study compared the status of chronic diseases among immigrants and the Korean population. Methods: This study was conducted on 153 immigrants living in Gwangju Metropolitan City in 2022. For comparison, 459 Koreans were selected using the 2021 Korea National Health and Nutrition Examination Survey (KNHANES). A survey was conducted on the management status of hypertension, diabetes, and hyperlipidemia using a questionnaire. Results: Immigrants were significantly more likely to have hypertension (50.3% vs. 24.2%, p<0.001) and diabetes (19.0% vs. 11.5%, p=0.002) than Koreans. In awareness, immigrants had significantly lower rates of hypertension (57.1% vs. 73.0%, p=0.031) and hyperlipidemia (immigrants 25.4% vs. 44.5%, p=0.006). In treatment rates, immigrants had significantly lower rates of hypertension (40.3% vs. 69.4%, <0.001) and hyperlipidemia (17.9% vs. 39.6%, p=0.003). In control rates, immigrants had significantly lower rates of hypertension (18.2% vs. 62.2%, <0.001) than Koreans. Conclusions: Chronic diseases are common among immigrants, but awareness, treatment, and control rates are low, so education and prevention policies are critical to improving immigrants' access to medical care and raising awareness.

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.7
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• pp.966-974
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• 2010

The aim of this study was to examine characteristics between nutrient intakes, body composition and physical fitness in gifted athletic boys. The subjects were conducted in 50 boys aged 9~12 years living in Busan, Ulsan and Gyeongsangnam-do, Korea. Dietary intake information was collected from participants using 3-day food recorded and body composition was measured by bioelectrical impedance analysis, and their anthropometric parameters were measured. Swimming group's daily energy intakes were significantly higher compared to those of other groups. Athletics and swimming groups were significantly taller than gymnastics. Swimming group was significantly higher than gymnastics group in weight, fat mass, body fat percent and lean body mass. Athletics and swimming groups were significantly longer than gymnastics group in sit and ball throwing. Swimming group was significantly better than other groups in sit up, and athletics group was significantly faster than gymnastics group in 50 m run. In correlation result for nutrient intake and body composition: 1) Body weight shows positive correlation with protein, phosphorus, sodium, vitamin $B_1$, C and niacin. BMI shows positive correlation with sodium and niacin. Fat mass shows positive correlation with niacin and folate. Body fat% shows positive correlation with vitamin C, E, niacin and folate. LBM shows positive correlation with all elements except lipid, calcium, vitamin A, C, E and folate. In correlation result for nutrient intake and physical fitness: 2) Push up shows positive correlation with iron and vitamin C. Sit and throw ball shows positive correlation with the events except lipid, fiber, vitamin A, E and folate. Sit up shows positive correlation with vitamin $B_1$. Half squat shows positive correlation with iron. Standing long jump shows positive correlation with total energy, lipid, and vitamin A, B and $B_2$. Long run shows negative correlation with protein, carbohydrate, fiber, phosphorus, iron, sodium and zinc. Side step shows positive correlation with niacin. Sit and reach shows negative correlation with total energy, carbohydrate, phosphorus, sodium, zinc and vitamin $B_2$. In correlation result for body composition and physical fitness: 3) Sit and throw ball shows positive correlation with body weight, BMI, fat mass, body fat% and LBM. Standing long jump shows positive correlation with LBM. But long run and 50 m run shows negative correlation with body weight and LBM.