• 치과방사선
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• 제14권1호
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• pp.135-140
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• 1984

In spite of many projections of TMJ, there are rarely satisfactory projections of TMJ. The author traced and measured the P-A cephalograms, which number is 70 in each male and female, them finding the following results. 1. The long axis of the condyle is 19.80㎜ on the right, and 19.89㎜ on the left in male, and that of 18.65㎜ on the right and 18.10㎜ on the left in female. 2. The intercondylar distance is 119.02㎜ in male, and 108.20㎜ in female, resulting that the intercondylar distance in male is much longer than that in female. 3. The right and left deviation of the midline passing through the center of the intercondylar distance and prosthion is +0.37㎜ in male, +0.64㎜ in female, and its range is from -4.6 to +5.7㎜ in male, and from -3.2 to +6.1㎜ in female, resulting that prosthion nearly coincides with midline. 4. The angle of the intercondylar distance and the long axis (vertical angle) is +5.48' in male, and +6.02' in female, resulting that there is a little difference between male and female and the angle of the right is greater than that of the left in both male and female. 5. The typology of the condyle in sum of male and female is; Right: A type 55 (39.3%), B type 66 (47.1%), C type, 12 (8.6%), D type, 7 (5.0%), E type, 0 (0%) Left: A type, 60 (42.9%), B type, 58 (41.4%), C type, 14 (10.0%), D type, 8 (5.7%), E type, 0 (0%) 6. The distribution of the typology between the right and the left is; AA 26 (18.6%), AB 50 (35.7%), AC 10 (7.1%), AD 3 (2.1%) BB 26 (18.6%), BC 13 (9.3%), BD 9 (6.4%), CC 0 (0%), CD 3 (2.1%)

• BMB Reports
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• 제55권6호
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• pp.293-298
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• 2022

Antipsychotics have been widely accepted as a treatment of choice for psychiatric illnesses such as schizophrenia. While atypical antipsychotics such as aripiprazole are not associated with obesity and diabetes, olanzapine is still widely used based on the anticipation that it is more effective in treating severe schizophrenia than aripiprazole, despite its metabolic side effects. To address metabolic problems, metformin is widely prescribed. Hypothalamic proopiomelanocortin (POMC) neurons have been identified as the main regulator of metabolism and energy expenditure. Although the relation between POMC neurons and metabolic disorders is well established, little is known about the effects of olanzapine and metformin on hypothalamic POMC neurons. In the present study, we investigated the effect of olanzapine and metformin on the hypothalamic POMC neurons in female mice. Olanzapine administration for 5 days significantly decreased Pomc mRNA expression, POMC neuron numbers, POMC projections, and induced leptin resistance before the onset of obesity. It was also observed that coadministration of metformin with olanzapine not only increased POMC neuron numbers and projections but also improved the leptin response of POMC neurons in the olanzapine-treated female mice. These findings suggest that olanzapine-induced hypothalamic POMC neuron abnormality and leptin resistance, which can be ameliorated by metformin administration, are the possible causes of subsequent hyperphagia.

• 한국농공학회논문집
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• 제55권4호
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• pp.95-106
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• 2013

It is now generally known that dynamical climate modeling outputs include systematic biases in reproducing the properties of atmospheric variables such as, preciptation and temerature. There is thus, general consensus among the researchers about the need of bias-correction process prior to using climate model results especially for hydrologic applications. Among the number of bias-correction methods, distribution (e.g., cumulative distribution fuction, CDF) mapping based approach has been evaluated as one of the skillful techniques. This study investigates the uncertainty of using various CDF mapping-based methods for bias-correciton in assessing regional climate change Impacts. Two different dynamicailly-downscaled Global Circulation Model results (CCSM and GFDL under ARES4 A2 scenario) using Regional Spectial Model for retrospective peiod (1969-2000) and future period (2039-2069) were collected over the west central Florida. Total 12 possible methods (i.e., 3 for developing distribution by each of 4 for estimating biases in future projections) were examined and the variations among the results using different methods were evaluated in various ways. The results for daily temperature showed that while mean and standard deviation of Tmax and Tmin has relatively small variation among the bias-correction methods, monthly maximum values showed as significant variation (~2'C) as the mean differences between the retrospective simulations and future projections. The accuracy of raw preciptiation predictions was much worse than temerature and bias-corrected results appreared to be more significantly influenced by the methodologies. Furthermore the uncertainty of bias-correction was found to be relevant to the performance of climate model (i.e., CCSM results which showed relatively worse accuracy showed larger variation among the bias-correction methods). Concludingly bias-correction methodology is an important sourse of uncertainty among other processes that may be required for cliamte change impact assessment. This study underscores the need to carefully select a bias-correction method and that the approach for any given analysis should depend on the research question being asked.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4387-4392
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• 2013

Projection of load of cancer mortality helps in quantifying the burden of cancer and is essential for planning cancer control activities. As per our knowledge, there have not been many attempts to project the cancer mortality burden at the country level in India mainly due to lack of data on cancer mortality at the national and state level. This is an attempt to understand the magnitude of cancer mortality problem for the various calendar years from 2011 to 2026 at 5-yearly intervals. Age, sex and site-wise specific cancer mortality data along with populations covered by the registries were obtained from the report of National Cancer Registry Programme published by Indian Council of Medical Research for the period 2001-2004. Pooled age sex specific cancer mortality rates were obtained by taking weighted average of these six registries with respective registry populations as weights. The pooled mortality rates were assumed to represent the country's mortality rates. Populations of the country according to age and sex exposed to the risk of cancer mortality in different calendar years were obtained from the report of Registrar General of India providing population projections for the country for the years from 2011 to 2026. Population forecasts were combined with the pooled mortality rates to estimate the projected number of cancer mortality cases by age, sex and site of cancer at various 5-yearly periods Viz. 2011, 2016, 2021 and 2026. The projections were carried out for the various cancer-leading sites as well as for 'all sites' of cancer. The results revealed that an estimated 0.44 million died due to cancer during the year 2011, while 0.51 million and 0.60 million persons are likely to die from cancer in 2016 and 2021. In the year 2011 male mortality was estimated to be 0.23 million and female mortality to be 0.20 million. The estimated cancer mortality would increase to 0.70 million by the year 2026 as a result of change in size and composition of population. In males increase will be to 0.38 millions and in females to 0.32 millions. Among women, cancer of the breast, cervical and ovary account for 34 percent of all cancer deaths. The leading sites of cancer mortality in males are lung, oesophagus, prostrate and stomach. The above results show a need for commitment for tackling cancer by reducing risk factors and strengthening the existing screening and treatment facilities.

• 핵의학기술
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• 제25권2호
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• pp.15-24
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• 2021

SPECT/CT는 보급 초기에 뛰어난 보정방법과 융합영상을 기반으로 한 정성적 기능이 주목받았고, 최근 동반진단치료(Theranostics)등의 도입으로 그 정량적 기능에 대한 관심과 활용이 증가되는 추세이다. PET/CT와 달리 SPECT/CT의 절대 정량화는 조준기의 종류, 검출기 회전과 같은 조건들이 영상획득과 재구성 방법 등에 까다로운 요소로 작용하고 있다. 따라서 본 연구에서는 SPECT/CT 촬영조건 중 투영상수와 투영상당 획득시간에 따른 총 획득시간(검사시간)의 증·감이 방사능농도 추정치에 미치는 영향을 알아보고자 한다. 부피 9,293 ml의 원통형 팬텀에 멸균수를 가득 채운 후 99mTcO4- 91.76 MBq를 희석하여 총 획득시간 600 sec(10 sec/frame × 120 frames, matrix size 128 × 128)의 조건으로 기준영상을 촬영하였고, 체적감도와 교정인자를 확인하였다. 기준영상을 중심으로 총 획득시간을 60(-90%), 150(-75%), 300(-50%), 450(-25%), 900(+50%), 1200(+100%) sec/frame으로 증·감시켜 비교영상을 획득하였고, 각 영상별 세부조건은 투영상당 획득시간(sec/frame)을 1.0, 2.5, 5.0, 7.5, 15.0, 20.0 sec/frame(투영상수 120frames 고정)로, 투영상수를 12, 30, 60, 90, 180, 240 frames(투영상당 획득시간 10 sec/frame 고정)로 설정하였다. 획득된 각 영상에서 관심체적을 통하여 측정한 계수를 바탕으로 정성적 평가로서 CNR(Contrast to Noise Ratio)의 변동률(%)을 확인하였고, 방사능농도 추정치의 변동률(%)을 통해서는 정량적 평가를 시행하였다. 이때 방사능농도 추정치(cps/ml)와 실제 방사능농도(Bq/ml)의 관계는 회복계수(RC_Recovery Coefficients)를 지표로 비교·분석하였다. 투영상수 변화에 따른 결과[CNR 변동률(%), 방사능농도 추정치 변동률(%), RC]는 총 획득시간 증감률(%) -90%에서 [-89.5%, +3.90%, 1.04], -75%에서 [-77.9%, +2.71%, 1.03], -50%에서 [-55.6%, +1.85%, 1.02], -25%에서 [-33.6%, +1.37%, 1.01], +50%에서 [+33.7%, +0.71%, 1.01], +100%에서 [+93.2%, +0.32%, 1.00]이었으며, 투영상당 획득시간 변화에 따른 결과는 총 획득시간 증감률(%)-90%에서 [-89.3%, -3.55%, 0.96], -75%에서 [-73.4%, -0.17%, 1.00], -50%에서 [-49.6%, -0.34%, 1.00], -25%에서 [-24.9%, 0.03%, 1.00], +50%에서 [+49.3%, -0.04%, 1.00], +100%에서 [+99.0%, +0.11%, 1.00]이었다. SPECT/CT에서 총 획득시간의 증·감에 따라 획득된 총 계수와 그에 따른 영상품질(CNR)은 비례하여 변화하는 양상을 보였지만, 절대 정량화를 통한 정량적 평가에서는 모든 실험조건에서 5% 미만(-3.55에서 +3.90%)의 변화를 보여 큰 영향을 받지 않고 정량적 정확성(RC 0.96에서 1.04)을 유지하였다. 검사시간의 증가보다는 단축을 우선하여 고려하였을 때 총 획득시간 감소는 정성적 기능에 있어서 기존에도 배제할 수 없었던 사항이지만 정량적 기능은 큰 손실 없이 적용 가능하여 임상적으로 실효성이 있다고 판단된다. 다만 총 획득시간의 증·감 시 동일한 검사시간이라면 투영상수의 변경보다는 투영상당 획득시간의 변경이 정성적, 정량적으로 조건변화에 따른 변동 폭이 적은 것으로 나타났다.

• 한국방사선학회논문지
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• 제17권1호
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• pp.141-148
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• 2023

CT에서 대수적재구성기법은 잡음에 강점을 가지는 재구성기법으로 알려져 있다. 대수적재구성기법에서 반복 횟수는 계산 시간을 결정하는 중요한 인자 중의 하나이다. 그러나 반복 횟수에 대한 기준이 연구되어 있지만 수백 번 이상의 반복을 수행하게 되어 현실적으로 사용하기에는 무리가 있었다. 본 연구에서는 반복 횟수를 결정할 수 있는 현실적인 방법을 제시하였다. 반복 횟수에 따라 단면 영상의 품질이 천천히 개선된다는 것을 이용하였다. 반복 횟수를 절대치 평균 오차의 차이 𝜖 < 0.001 로 선택하였다. 잡음이 없는 경우는 Shepp-Logan 두부 팬텀을 이용하였고 잡음이 있는 경우는 Geant4를 이용하여 다양한 입사광자에 대해 360, 720, 1,440개의 투영을 얻었다. 정지 조건에서 10회 내외의 반복으로 우수한 단면 영상을 획득하였다. 수 백회 이상을 반복하는 최적 영상기반의 방법에 비해 현실적으로 적용 가능성이 높은 방법이 될 수 있을 것이다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.704-709
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• 2004

This paper presents the laser processing to adjust the roll and pitch directions of the flex suspension assembly for hard disk drive production. The adjustment is accomplished using a number of laser beam projections that can be approximated using the regression model of the existing measured roll and pitch directions. Information derived from the analysis can be applied to control the quality of flex suspension assembly. The performances of the proposed technique were observed using the flex suspension assembly plant in Thailand as an illustrative case study. The experimental results are given to support the improving manufacturing yields and some economic benefits of the proposed technique.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.484-488
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• 1997

In this Paper, We use Maximum-Intensity Projection(MIP) algorithms. Maximum-Intensity Projection algorithms currently used for construction of magnetic resonance angiograms. The blood flow in a volume of interest is represented by bright intensities in the MR data volume. The flow within the vasculature shows up in the projections plane. By relating the intensities of the pixel to their location in the slice, the total number of pixels considered for the projection plane was reduced, thus saving calculation time. The algorithm was written in visual C++.

• Journal of Communications and Networks
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• 제5권4호
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• pp.328-343
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• 2003

Orthogonal pulse-shape modulation using Hermite pulses for ultra-wideband communications is reviewed. Closedform expressions of cross-correlations among Hermite pulses and their corresponding transmit and receive waveforms are provided. These show that the pulses lose orthogonality at the receiver in the presence of differentiating antennas. Using these expressions, an algebraic model is established based on the projections of distorted receive waveforms onto the orthonormal basis given by the set of normalized orthogonal Hermite pulses. Using this new matrix model, a number of pulse-shape modulation schemes are analyzed and a novel orthogonal design is proposed. In the proposed orthogonal design, transmit waveforms are constructed as combinations of elementary Hermites with weighting coefficients derived by employing the Gram-Schmidt (QR) factorization of the differentiating distortion model’s matrix. The design ensures orthogonality of the vectors at the output of the receiver bank of correlators, without requiring compensation for the distortion introduced by the antennas. In addition, a new set of elementary Hermite Pulses is proposed which further enhances the performance of the new design while enabling a simplified hardware implementation.

• 한국경영과학회지
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• 제3권2호
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• pp.75-90
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• 1978

The objective of this paper is to demonstrate how System Dynamics Approach may be used to develop new ways of analyzing and projecting manpower requirements and resources. For this purpose, a System Dynamics Model is presented as an example. An examination of the model will show that a System Dynamics modeling approach is an innovative and useful tool for manpower policy analysis and planning. Second, with minor modifications, the model may be used for manpower policy analysis and planning for any skilled personnel in Korea. For example, a similar model nay be built for engineers to analyze the effects of alternative policies about engineering education, sur as the number of available places in the various institutions of training, scholarships and loans, and the duration of training. An engineer's model may also be used to make the projections of the supply and requirements of engineers in the future according to various alternative assumptions where each assumption represents a policy option.