• 한방안이비인후피부과학회지
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• 제28권3호
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• pp.30-47
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• 2015

Objective : Melanoma is a very critical and devastating disease. Although many people have depended on surgical operation in melanoma treatment, they have placed importance on non-invasive methods constantly. So we planned to establish a research methodology by analysing existing articles containing conservative melanoma treatments in Journals of Korean Medicine published in Korea.Methods : Using search words of anti-cancer, B16, cancer, lung metastasis, melanoma, metastasis, S-100, SK-MEL, tumor, tyrosinase, we collected 26 articles by searching internet portal sites as following;Using search words of anti-cancer, B16, cancer, lung metastasis, melanoma, metastasis, S-100, SK-MEL, tumor, tyrosinase, we collected 26 articles by searching internet portal sites as followinghttp://oasis.kiom.re.kr,http://www.koreantk.com,http://www.riss.kr,http://www.dbpia.co.kr,http://www.ndsl.kr,http://kiss.kstudy.com,http://www.naver.com,http://www.google.com.Result : The number of articles is 26 and in the year of 2003, 2004 is ranked the highest number in publication. The journal of acupuncture & moxibustion society ranked the highest(30.8%). 2 and 4 authors ranked the highest(26.9%) in number of authors. T-test ranked the highest(58.1%) in statistics methods. P.O. med indicated in 11 articles and Pharmacopuncture in 15 articles. B16 murine melanoma cell was indicated in 25 articles by cancer-induced methods. In measurement, T cell activity was indicated in 14 articles, NK activity in 4 articles, IL-2 in 6 articles, apoptosis in 1 article, lung metastasis in 14 articles.Conclusion : Considering overall results, it is necessary to diversify cancer-induced methods and measurement methods in experimental melanoma research.

• Korean Journal of Radiology
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• 제1권1호
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• pp.38-42
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• 2000

Objective: The purpose of this study was to determine the utility of preoperative CT in predicting early recurrence of hepatocellular carcinoma after partial hepatic resection. Materials and Methods: Preoperative three-phase helical CT scans in 53 patients with hepatocellular carcinoma were retrospectively reviewed by two radiologists. In 27 patients (group I), HCC had recurred within six months, while 26 (group II) had remained disease free for at least two years. In each group, preoperative CT findings were evaluated in each group for the tumor size and number, the presence or absence of capsule, distinctness of tumor margin, perinodular extension, and the presence or absence of portal vein thrombosis. Results: In group I, a tumor capsule of tumor was seen in five of 27 patients (19%), and in group II, in 16 of 26 (62%) (p = .001). The tumor margin was distinct in eight patients (30%) in group I and in 20 (77%) in group II (p = .001). Multiple tumors, perinodular extension, and portal vein thrombosis were more frequently seen in group I but the differences were not statistically significant (p > .05). Tumor size was similar in each group (p > .05). Conclusion: Preoperative CT findings that may help predict the early recurrence of hepatocellular carcinoma after surgical resection are an absence of capsule of tumors and an indistinct margin. Reference to these findings during preoperative CT can guide clinicians in their choice of treatment.

• 대한핵의학회지
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• 제24권2호
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• pp.274-278
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• 1990

Metastases to the liver presents a common clinical problem in the management of patients with cole-rectal cancer, and are responsible for a high degree of morbidity and mortality associated with this malignancy. Unfortunately, attempts at preventing the development of liver metastases in "high risk" patients has so far been unsuccessful. Ongoing studies of adjuvant chemotherapy have not yet illustrated a significant increase in survival in patients receiving such therapy. The purpose of the study is to investigate the value of adjuvant radiotherapy given in the form of colloidal chromic phosphate P-32 suspension administered via portal vein after radical resection of the primary cancer, in preventing the growth of occult metastases in the liver. Twenty one patients (10 patients of treated group with 11 controls) were followed 18 months after operation. There was no significant change in the CBC and liver functions after administration of P-32 labeled colloidal chromic phosphate. The number of patients who showed local metastases at 18 months were 2 in the treated group and 3 in the control group. While liver metastases occurred in one patient at 6 months and in three at 12 months in the control group, there was no development of liver metastases by 12 months in the treated group. At 18 month follow-up CT scan one patient in the treated group showed a single nodule in the liver. In conclusion liver metastasis rate was lower in the patients who received colloidal P-32 chromic phosphate via portal vein after radical resection of the primary cole-rectal cancer.

• 응용통계연구
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• 제29권4호
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• pp.657-678
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• 2016

본 연구는 영화 흥행에 미치는 온라인 구전 변수들의 영향을 다루었다. 2012년 부터 2015년까지 4년 동안 국내에서 개봉한 총 관객 수 50만 이상인 276편의 영화에 대한 통계분석 결과 개봉 후 포털의 평가자 수, 개봉 후 블로그 수, 개봉 후 뉴스 수와 같은 온라인 구전의 크기를 나타내는 변수들이 온라인 구전의 방향을 나타내는 개봉 후 포털의 평점이나 혹은 영화의 내재적 속성을 나타내는 변수들로서 감독, 배우, 배급사, 등급, 국적, 개봉 월, 개봉 계절 등 보다 영화 흥행과 더욱 연관성이 있었다.

• 대한인간공학회지
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• 제22권3호
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• pp.13-26
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• 2003

The purpose of this study is to investigate the present conditions of the night work and shift work systems in the heavy chemical industrial complexes found in Changwon, Masan, and Chinhae. Korea. We will attempt to define and classify their problems; and to discover further ways to improve their systems. Fifty production factories were carefully selected as the subjects for this study. The shift systems were classified into five categories. The consecutive night shifts were long in almost all cases with 6 days (36 factories) and 7 days (13 factories). It was found that the night work of about] 2 hours continues for a long period in the weekly rotation full-day shift systems and the night-including non-full-day shift systems, and there was no holiday during a shift cycle in the continuous full-day shift systems. The work time in most shift systems was longer than the 44-hours/week permitted by Korean law. Considering the characteristics of these various types of shift systems, the most essential thing to reduce the shift workers' work load may be to shorten their working hours and improve the schedule of shift systems. It is highly recommended as a fundamental solution. to reduce the portal-to-portal hours from 12 to 8 in the night-including non-full-day shift systems and the weekly rotation full-day shift systems, and at least to employ a 4-team 3-shift system in the continuous full-day shift systems. In addition to this, it should from now on be taken as a goal to restructure the types of shift systems by taking such measures as avoiding continuous night work if possible, providing sufficient off-duty intervals both before and after night shift, providing increased opportunities for workers to nap during night work. and increasing the number of holidays.

• Clinics in Shoulder and Elbow
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• 제20권4호
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• pp.201-207
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• 2017

Background: The blunted tip of a reusable with multiple uses can cause problems with the passing procedure in arthroscopic Bankart repair. This study assessed the advantage of Scorpion with a $70^{\circ}$ arthroscope in arthroscopic Bankart repair compared to hook typed suture passer. Methods: Scorpion in 19 patients, the hook type suture passer (conventional group) in 18 patients were used. All patients underwent the same procedure except for the type of suture passer used. Another different point of the procedure were telescopes and the number of portals used; three arthroscopic portals (posterior, anterorsuperiorlateral, and mid-anterior) and a $30^{\circ}$ arthroscope in the conventional group, but two portals and a $70^{\circ}$ arthroscope as well as the $30^{\circ}$ one in the Scorpion group. The surgery time and the surgical complications including an iatrogenic axillary nerve injury were recorded. Results: The Scorpion group showed a significant decrease in surgery time compared to the conventional group. In contrast to the conventional group, Scorpion provided an easy estimation of the exit of suture passing, no iatrogenic labral injury during the passing procedure with straight movement and the sharp tip of the knife installed. Iatrogenic supraspinatus injuries could be avoided when making an accessory anteosuperiorlateral portal due to the $70^{\circ}$ arthroscope. Conclusions: In arthroscopic Bankart repair, the use of the Scorpion suture passer and a $70^{\circ}$ arthroscope can reduce the surgery time, avoid unnecessary supraspinatus injury, and avoid iatrogenic axillary nerve damage through the relatively easy and precise suture passing and saving of the anterosuperior portal.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3509-3514
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• 2013

The prognostic value of the fibroblast growth factor-inducible 14 (Fn14) expression in hepatocellular carcinoma (HCC) is unknown. Real-time PCR (RT-PCR), western blot assays and immunohistochemistry analysis were here performed in order to compare Fn14 expressios in paired liver samples of HCC and normal liver tissue. Most of the tumor tissues expressed significantly higher levels of Fn14 compared to adjacent non-tumor tissues, with Fn14High accounting for 54.6% (142/260) of all patients. The Pearson ${\chi}^2$ test indicated that Fn14 expression was closely associated with serum alpha fetal protein (AFP) (P=0.002) and tumor number (p=0.019). Univariate and multivariate analyses revealed that along with tumor diameter and portal vein tumor thrombosis (PVTT ) type, Fn14 was an independent prognostic factor for both overall survival (OS) (HR=1.398, p=0.008) and recurrence (HR=1.541, p=0.001) rates. Fn14 overexpression HCC correlated with poor surgical outcome, and this molecule may be a candidate biomarker for prognosis as well as a target for therapy.

• 한국문헌정보학회지
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• 제44권4호
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• pp.395-412
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• 2010

본 연구에서는 국내 주요 검색 포털들인 네이버, 네이트, 다음, 야후, 파란, 구글에서 제공하는 멀티미디어 검색 서비스를 메타데이터, 검색 기능, 검색 방법, 부가 기능, 결과 출력 방식 등의 관점에서 비교, 분석하였다. 조사 결과, 모든 포털들이 이미지, 동영상 검색을 제공하는데 비해 음악 검색은 네이버, 네이트, 다음만이 제공하고 있었다. 또한 음악 검색보다는 이미지, 동영상 검색에서 검색 기능이나 부가 서비스의 개발이 보다 활발하게 진행되고 있었다. 네이버, 네이트, 다음은 국외 검색 포털들이 제공하지 않는 다양한 멀티미디어 검색 기능을 개발, 제공하고 있었고, 구글은 다양한 수준의 고급 검색 기능을 제공하고 있었다. 반면, 국내 포털들은 검색 결과에서 매우 제한적인 메타데이터만 제공하고 있었다. 본 연구의 결과는 포털들의 멀티미디어 검색 서비스의 개선에 활용될 수 있을 것으로 기대된다.

• 한국간담췌외과학회지
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• 제28권2호
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• pp.134-143
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• 2024

Backgrounds/Aims: The hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is classified as the advanced stage (BCLC stage C) with extremely poor prognosis, and in current guidelines is recommended for systemic therapy. This study aimed to evaluate the surgical outcomes and long-term prognosis after hepatic resection (HR) for patients who have HCC combined with PVTT. Methods: We retrospectively analyzed 332 patients who underwent HR for HCC with PVTT at ten tertiary referral hospitals in South Korea. Results: The median overall and recurrence-free survival after HR were 32.4 and 8.6 months, while the 1-, 3-, and 5-year overall survival rates were 75%, 48%, and 39%, respectively. In multivariate analysis, tumor number, tumor size, AFP, PIVKA-II, neutrophil-to-lymphocyte ratio, and albumin-bilirubin (ALBI) grade were significant prognostic factors. The risk scoring was developed using these seven factors-tumor, inflammation and hepatic function (TIF), to predict patient prognosis. The prognosis of the patients was well stratified according to the scores (log-rank test, p < 0.001). Conclusions: HR for patients who have HCC combined with PVTT provided favorable survival outcomes. The risk scoring was useful in predicting prognosis, and determining the appropriate treatment strategy for those patients who have HCC with PVTT.

• 한국인터넷방송통신학회논문지
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• 제18권3호
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• pp.1-7
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• 2018

연구의 목적은 3개 모바일 포털사이트의 응답시간을 분포를 이용하여 비교하고 분류하는 것이다. 연구대상은 Naver, Daum, Nate의 모바일 포털 사이트 접속페이지이며, 실험기간은 모바일 포털들이 활성화되기 시작되던 즈음인 2012년 4월 18일에서 2018년 4월 17일까지 6년간이다. 그리고 실험횟수는 4,060회이다. 분포비교를 위해 히스토그램과 백분율을 이용하였으며 이론적인 비교를 위해 모수적 방법인 카이스케어 검정과 비모수적 방법인 콜모고로프-스미르노프 검정을 실시하였다. 네가지 방법 모두 Naver가 가장 빨랐고, 다음이 Nate, Daum이 가장 느렸다. 평균 응답시간 면에서도 같은 결과를 낳았다. 이러한 결과는 유선 포털의 결과와 정반대로서, Naver는 매체 특성에 맞게 유선에서는 많은 콘텐츠를 무선에서는 응답시간을 높이는 전략이고, Daum은 무선에서 응답시간을 희생하면서 콘텐츠를 중시하는 전략을 구사하고 있음을 알 수 있다. 분류에서는 응답시간에 따라 "Comfortable"과 "Tolerable", "Feedback", "Leave"로 나누었으며, 이용자들이 떠날 수 있다는 7초 이상인 "Leave"의 비율이 Naver는 1.18%, Daum이 11.70%, Nate가 1.5%로 Daum이 압도적으로 높아서 Daum의 응답시간은 개선이 매우 절실한 수준임을 알 수 있다. 또한 분류 결과에 의하면 3개 모바일 포털들이 응답시간을 줄이는 것이 필요하다는 것을 밝혔다. 본 논문의 결과가 모바일 포털들의 응답시간을 줄이는 기술경쟁을 촉진할 수 있기를 기대한다.