Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Early Recurring Hepatocellular Carcinoma after Partial Hepatic Resection: Preoperative CT Findings

  • Jae Hoon Lim (Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Hyun-Jung Jang (Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Eung Yeop Kim (Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Cheol Keun Park (Department of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Jae-Won Joh (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Yong Il Kim (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 1999.10.19
  • Accepted : 2000.02.09
  • Published : 2000.03.31
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Abstract

Objective: The purpose of this study was to determine the utility of preoperative CT in predicting early recurrence of hepatocellular carcinoma after partial hepatic resection. Materials and Methods: Preoperative three-phase helical CT scans in 53 patients with hepatocellular carcinoma were retrospectively reviewed by two radiologists. In 27 patients (group I), HCC had recurred within six months, while 26 (group II) had remained disease free for at least two years. In each group, preoperative CT findings were evaluated in each group for the tumor size and number, the presence or absence of capsule, distinctness of tumor margin, perinodular extension, and the presence or absence of portal vein thrombosis. Results: In group I, a tumor capsule of tumor was seen in five of 27 patients (19%), and in group II, in 16 of 26 (62%) (p = .001). The tumor margin was distinct in eight patients (30%) in group I and in 20 (77%) in group II (p = .001). Multiple tumors, perinodular extension, and portal vein thrombosis were more frequently seen in group I but the differences were not statistically significant (p > .05). Tumor size was similar in each group (p > .05). Conclusion: Preoperative CT findings that may help predict the early recurrence of hepatocellular carcinoma after surgical resection are an absence of capsule of tumors and an indistinct margin. Reference to these findings during preoperative CT can guide clinicians in their choice of treatment.

Keywords

Acknowledgement

This work was supported by the Samsung Medical Center Grant.

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