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Detailed Analysis of Thrust Plume and Satellite Base Region Interaction (인공위성 플룸과 기저면의 상호 작용에 관한 해석)

  • Kim, Jae-Gang;Kwon, Oh-Joon;Lee, Kyun-Ho;Kim, Su-Kyum;Yu, Myoung-Jong
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.36 no.11
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    • pp.1056-1062
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    • 2008
  • The interaction between thrust plume and satellite base region was investigated by using direct simulate Monte-Carlo calculations. For the accurate simulation of N2 and H2 collisions and rotation-translation transition, a variable soft-sphere model and a recent rotational relaxation model of N2 and H2 were used. For the investigation of the interaction between thrust plume and base region, the number density distribution for each species, translational and rotational temperature distributions, heat flux, and pressure were examined by direct simulation of Monte-Carlo calculations. It was found that most of the surface properties are affected by H2 collisions and a strong non-equilibrium state is observed at the base region. It was demonstrated that an accurate model is needed to simulate H2 collisions and the rotation-translation transition. The results by the present calculation are more accurate than previous direct simulation Monte-Carlo calculations because more accurate rotational relaxation models were used in simulating the inelastic collisions.

First Report of Peach Fruit Rot Caused by Fusarium avenaceum in Korea (Fusarium avenaceum에 의한 복숭아 신규 과실 썩음병 발생 보고)

  • Heo, A Yeong;Koo, Young Mo;Choi, Young-Joon;Kim, Sang Hee;Chung, Gyu Young;Choi, Hyong Woo
    • Research in Plant Disease
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    • v.26 no.1
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    • pp.48-52
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    • 2020
  • In July 2019, typical rot symptom was observed on peach fruits harvested from the fields at Andong, Korea. As the disease progressed, white and purple colored mycelial mat developed on the surface of the infected fruits. A causal pathogen was isolated from the infected fruit and cultured on potato dextrose agar media for identification. Fungal colonies on potato dextrose agar produced 3 pigments, including purple, yellow, and white colors. The isolate incited fruit rot symptoms on artificially inoculated peach fruits, from which the same fungus was isolated, fulfilling Koch's postulates. Based on the morphological characteristics and sequence analysis of rDNA internal transcribed spacer, translation elongation factor 1-alpha, and β-tubulin, the causal agent of the disease was identified as Fusarium avenaceum. This study is the first report of fruit rot of peach fruits caused by Fusarium avenaceum in Korea.

Apoptosis-Induced Gene Profiles of a Myeloma Cell P3-X63-Ag8.653

  • Bahng, Hye-Seung;Chung, Yong-Hoon
    • IMMUNE NETWORK
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    • v.6 no.3
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    • pp.128-137
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    • 2006
  • Background: Apoptosis is a physiologic phenomenon involved in development, elimination of damaged cells, and maintenance of cell homeostasis. Deregulation of apoptosis may cause diseases, such as cancers, immune diseases, and neurodegenerative disorders. The mouse myeloma cell P3-X63-Ag8.653 (v653) is an HGPRT deficient $(HGPRT^-)$ mutant strain. High dependency on de novo transcription and translation of aminopterin induced apoptosis of this cell seems to be an ideal experimental system for searching apoptosis-induced genes. Methods & Results: For searching apoptosis-related genes we carried out GE-array (dot blot), Affymetrix GeneChip analysis, Northern analysis and differential display-PCR techniques. The chip data were analyzed with three different programs. 66 genes were selected through Affymetrix GeneChip analyses. All genes selected were classified into 8 groups according to their known functions. They were Genes of 1) Cell growth/maintenance/death/enzyme, 2) Cell cycle, 3) Chaperone, 4) Cancer/disease-related genes, 5) Mitochondria, 6) Membrane protein/signal transduction, 7) Nuclear protein/nucleic acid binding/transcription binding and 8) Translation factor. Among these groups number of genes were the largest in the genes of cell growth/maintenance/death/enzyme. Expression signals of most of all groups were peaked at 3 hour of apoptosis except genes of Nuclear protein/nucleic acid binding/transcription factor which showed maximum signal at 1 hour. Conclusion: This study showed induction of wide range of proapoptotic factors which accelerate cell death at various stage of cell death. In addition apoptosis studied in this research can be classified as a type 2 which involves cytochrome c and caspase 9 especially in early stages of death. But It also has progressed to type 1 in late stage of the death process.

A Unique Gene Expression Signature of 5-fluorouracil

  • Kim, Ja-Eun;Yoo, Chang-Hyuk;Park, Dong-Yoon;Lee, Han-Yong;Yoon, Jeong-Ho;Kim, Se-Nyun
    • Molecular & Cellular Toxicology
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    • v.1 no.4
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    • pp.248-255
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    • 2005
  • To understand the response of cancer cells to anticancer drugs at the gene expression level, we examined the gene expression changes in response to five anticancer drugs, 5-fluorouracil, cytarabine, cisplatin, paclitaxel, and cytochalasin D in NCI-H460 human lung cancer cells. Of the five drugs, 5-fluorouracil had the most distinctive gene expression signature. By clustering genes whose expression changed significantly, we identified three clusters with unique gene expression patterns. The first cluster reflected the up-regulation of gene expression by cisplatin, and included genes involved in cell death and DNA repair. The second cluster pointed to a general reduction of gene expression by most of the anticancer drugs tested. A number of genes in this cluster are involved in signal transduction that is important for communication between cells and reception of extracellular signals. The last cluster represented reduced gene expression in response to 5-fluorouracil, the genes involved being implicated in DNA metabolism, the cell cycle, and RNA processing. Since the gene expression signature of 5-fluorouracil was unique, we investigated it in more detail. Significance analysis of microarray data (SAM) identified 808 genes whose expression was significantly altered by 5-fluorouracil. Among the up-regulated genes, those affecting apoptosis were the most noteworthy. The down-regulated genes were mainly associated with transcription-and translation-related processes which are known targets of 5-fluorouracil. These results suggest that the gene expression signature of an anticancer drug is closely related to its physiological action and the response of caner cells.

An EXPRESS-to-XML Translator (EXPRESS 데이타를 XML 문서로 변환하는 번역기)

  • 이기호;김혜진
    • Journal of KIISE:Computing Practices and Letters
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    • v.8 no.6
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    • pp.746-755
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    • 2002
  • EXPRESS is product information description language. It is interpretable by human and software. Product data written in EXPRESS make it possible to exchange between heterogeneous systems. However, the number of software that can use EXPRESS is limited and it is expensive to use the software. XML makes it possible to update and manage data on the Web. Because the Web is easier to use and access than other tools comparatively, data represented by XML need not depend on specific applications or systems and it can be used for exchange of data. Therefore, if we represent EXPRESS-driven data in XML, there will be more active data exchange widely and easily In this work, a method of translation EXPRESS document to XML DTD and XML Schema is proposed. By classification all of EXPRESS syntax element and consideration complex cases caused by this syntax element, a translation rule that represent XML DTD and XML Schema is suggested. Also, a translator which is corresponding to this rule is implemented.

Calibration of Omnidirectional Camera by Considering Inlier Distribution (인라이어 분포를 이용한 전방향 카메라의 보정)

  • Hong, Hyun-Ki;Hwang, Yong-Ho
    • Journal of Korea Game Society
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    • v.7 no.4
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    • pp.63-70
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    • 2007
  • Since the fisheye lens has a wide field of view, it can capture the scene and illumination from all directions from far less number of omnidirectional images. Due to these advantages of the omnidirectional camera, it is widely used in surveillance and reconstruction of 3D structure of the scene In this paper, we present a new self-calibration algorithm of omnidirectional camera from uncalibrated images by considering the inlier distribution. First, one parametric non-linear projection model of omnidirectional camera is estimated with the known rotation and translation parameters. After deriving projection model, we can compute an essential matrix of the camera with unknown motions, and then determine the camera information: rotation and translations. The standard deviations are used as a quantitative measure to select a proper inlier set. The experimental results showed that we can achieve a precise estimation of the omnidirectional camera model and extrinsic parameters including rotation and translation.

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A Study on the Fabrication of p-type poly-Si Thin Film Transistor (TFT) Using Sequential Lateral Solidification(SLS) (SLS 공정을 이용한 p-type poly-Si TFT 제작에 관한 연구)

  • Lee, Yun-Jae;Park, Jeong-Ho;Kim, Dong-Hwan
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.51 no.6
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    • pp.229-235
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    • 2002
  • This paper presents the fabrication of polycrystalline thin film transistor(TFT) using sequential lateral solidification(SLS) of amorphous silicon. The fabricated SLS TFT showed high Performance suitable for active matrix liquid crystal display(AMLCD). The SLS process involves (1) a complete melting of selected area via irradiation through a patterned mask, and (2) a precisely controlled pulse translation of the sample with respect to the mask over a distance shorter than the super lateral growth(SLG) distance so that lateral growth extended over a number of iterative steps. The SLS experiment was performed with 550$\AA$ a-Si using 308nm XeCl laser having $2\mu\textrm{m}$ width. Irradiated laser energy density is 310mJ/$\textrm{cm}^2$ and pulse duration time was 25ns. The translation distance was 0.6$\mu$m/pulse, 0.8$\mu$m/pulse respectively. As a result, a directly solidified grain was obtained. Thin film transistors (TFTs) were fabricated on the poly-Si film made by SLS process. The characteristics of fabricated SLS p -type poly-Si TFT device with 2$\mu\textrm{m}$ channel width and 2$\mu\textrm{m}$ channel length showed the mobility of 115.5$\textrm{cm}^2$/V.s, the threshold voltage of -1.78V, subthreshold slope of 0.29V/dec, $I_{off}$ current of 7$\times$10$^{-l4}$A at $V_{DS}$ =-0.1V and $I_{on}$ / $I_{off}$ ratio of 2.4$\times$10$^{7}$ at $V_{DS}$ =-0.1V. As a result, SLS TFT showed superior characteristics to conventional poly-Si TFTs with identical geometry.y.y.y.

Domain Adaptation Method for LHMM-based English Part-of-Speech Tagger (LHMM기반 영어 형태소 품사 태거의 도메인 적응 방법)

  • Kwon, Oh-Woog;Kim, Young-Gil
    • Journal of KIISE:Computing Practices and Letters
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    • v.16 no.10
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    • pp.1000-1004
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    • 2010
  • A large number of current language processing systems use a part-of-speech tagger for preprocessing. Most language processing systems required a tagger with the highest possible accuracy. Specially, the use of domain-specific advantages has become a hot issue in machine translation community to improve the translation quality. This paper addresses a method for customizing an HMM or LHMM based English tagger from general domain to specific domain. The proposed method is to semi-automatically customize the output and transition probabilities of HMM or LHMM using domain-specific raw corpus. Through the experiments customizing to Patent domain, our LHMM tagger adapted by the proposed method shows the word tagging accuracy of 98.87% and the sentence tagging accuracy of 78.5%. Also, compared with the general tagger, our tagger improved the word tagging accuracy of 2.24% (ERR: 66.4%) and the sentence tagging accuracy of 41.0% (ERR: 65.6%).

Isogeometric Analysis of Lattice Structures Having Compression-Twist Coupled Deformation (압축-비틀림이 결합된 격자구조의 아이소-지오메트릭 해석)

  • Kang, Se-Hyeon;Choi, Myung-Jin;Oh, Myung-Hoon;Yoon, Min-Ho;Cho, Seonho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.34 no.5
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    • pp.287-292
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    • 2021
  • We utilized the isogeometric analysis (IGA) method that uses NURBS basis functions in CAD systems, to account for the geometric exactness of a geometrically exact beam deformation, on a new type of metamaterial, twist-translation coupled structure showing a large twist angle. A two-dimensional unit cell structure was embedded in a cylindrical wall, using free-form deformation and an appropriate interpolation scheme. A parametric study on the effects of the dimensions of the cylinder and the number of cells, on the twisting angle was performed. Furthermore, the mechanism of the twist-translation coupled metamaterial was explored through numerical examples.

Comparative Transcriptomic Analysis of MAPK-Mediated Regulation of Sectorization in Cryphonectria parasitica

  • Chun, Jeesun;So, Kum-Kang;Ko, Yo-Han;Kim, Jung-Mi;Kim, Dae-Hyuk
    • Molecules and Cells
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    • v.42 no.4
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    • pp.363-375
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    • 2019
  • Fungal sectorization is a complex trait that is still not fully understood. The unique phenotypic changes in sporadic sectorization in mutants of CpBck1, a mitogen-activated protein kinase kinase kinase (MAPKKK) gene, and CpSlt2, a mitogen-activated protein kinase (MAPK) gene, in the cell wall integrity pathway of the chestnut blight fungus Cryphonectria parasitica have been previously studied. Although several environmental and physiological factors cause this sectoring phenotype, genetic variants can also impact this complex morphogenesis. Therefore, RNA sequencing analysis was employed to identify candidate genes associated with sectorization traits and understand the genetic mechanism of this phenotype. Transcriptomic analysis of CpBck1 and CpSlt2 mutants and their sectored progeny strains revealed a number of differentially expressed genes (DEGs) related to various cellular processes. Approximately 70% of DEGs were common between the wild-type and each of CpBck1 and CpSlt2 mutants, indicating that CpBck1 and CpSlt2 are components of the same MAPK pathway, but each component governs specific sets of genes. Functional description of the DEGs between the parental mutants and their sectored progenies revealed several key pathways, including the biosynthesis of secondary metabolites, translation, amino acid metabolism, and carbohydrate metabolism; among these, pathways for secondary metabolism and translation appeared to be the most common pathway. The results of this comparative study provide a better understanding of the genetic regulation of sector formation and suggest that complex several regulatory pathways result in interplays between secondary metabolites and morphogenesis.