• Title/Summary/Keyword: Nuclear development

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Studies on the Heterosis Breeding in Rape by Using Cytoplasmic Genetic Male Sterile lines 3. Development of Complete Cytoplasmic Genetic Male Sterile Line "MOKPO-MS" Having Improved Quality of Oil and Oil Cake (세포질.유전자적 웅성불임 계통을 이용한 유채 Heterosis 육종에 관한 연구 제3보 유채 세포질 유전자적 웅성불임 계통의 불임안전성과 유.박의 성분 개량)

  • Lee, J.I.;Kwon, B.S.
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.25 no.3
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    • pp.50-58
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    • 1980
  • A cytoplasmic-genetic male sterile line(MS) in rapes of which fertility is not restored under any temperature regimes and have the better quaility of and oil cake was developed. A MS line named Mokpo-MS, which is form the cross between Tower and Isuzu and its stamens is degenerated completely by interact~g with cytoplasmic and nuclear genes was selected. This MS line was found as a complete cytoplasmic-genetic male sterile having the quality of oil and oil cake were greatly improved by introducing Zero-erucic and Zero-glucosinolate gene from Tower.

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Function of 27-Hydroxycholesterol in Various Tissues and Diseases (다양한 조직 및 질병에서 27-하이드록시콜레스테롤의 역할 및 기전 고찰)

  • Shim, Wan-Seog;Lee, Chanhee;Azamov, Bakhovuddin;Kim, Koanhoi;Lee, Dongjun;Song, Parkyong
    • Journal of Life Science
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    • v.32 no.3
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    • pp.256-262
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    • 2022
  • Oxysterols are oxygenated metabolites of cholesterol generated by serial enzymatic reactions during bile acid synthesis. Similar to cholesterol, oxysterols move rapidly to the intracellular region and modulate various cellular processes, such as immune cell responses, lipid metabolism, and cholesterol homeostasis. Different nuclear transcription factors, such as glucocorticoid, estrogen, and liver X receptors, can be modulated by oxysterols in multiple tissues. The most abundant oxysterol, 27-hydroxycholesterol (27-OHC), is a well-known selective modulator that can either activate or suppress estrogen receptor activity in a tissue-specific manner. The contribution of 27-OHC in atherosclerosis development is apparent because a large amount of it is found in atherosclerotic plaques, accelerating the transformation of macrophages into foam cells that uptake extracellular modified lipids. According to previous studies, however, there are opposing opinions about how 27-OHC affects lipid and cholesterol metabolism in metabolic organs, including the liver and adipose tissue. In particular, the effects of 27-OHC on lipid metabolism are entirely different between in vitro and in vivo conditions, suggesting that understanding the physiology of this oxysterol requires a sophisticated approach. This review summarizes the potential effects of 27-OHC in atherosclerosis and metabolic syndromes with a special discussion of its role in metabolic tissues.

The Utility of Chatbot for Learning in the Field of Radiology (방사선(학)과 분야에서 챗봇을 이용한 학습방법의 유용성)

  • Yoon-Seo Park;Yong-Ki Lee;Sung-Min Ahn
    • Journal of the Korean Society of Radiology
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    • v.17 no.3
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    • pp.411-416
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    • 2023
  • The purpose of this study is to investigate the utilization of major learning tools among radiology science students and assess the accuracy of a conversational artificial intelligence service program, specifically a chatbot, in the context of the national radiologic technologist licensing exam. The survey revealed that 84.3% of radiology science students actively utilize electronic devices during their learning process. In addition, 104 out of 140 respondents said they use search engines as a top priority for efficient data collection while studying. When asked about their awareness of chatbots, 80% of participants responded affirmatively, and 22.9% reported having used chatbots for academic purposes at least once. From 2018 to 2022, exam questions from the first and second periods were presented to the chatbot for answers. The results showed that ChatGPT's accuracy in answering first period questions increased from 48.28% to 60%, while for second period questions, it increased from 50% to 62.22%. Bing's accuracy in answering first period questions improved from 55% to 64.55%, and for second period questions, it increased from 48% to 52.22%. The study confirmed the general trend of radiology science students utilizing electronic devices for learning and obtaining information through the internet. However, conversational artificial intelligence service programs in the field of radiation science face challenges related to accuracy and reliability, and providing perfect solutions remains difficult, highlighting the need for continuous development and improvement.

The Meaning of Parenthood and Christian Educational Care (부모 됨의 의미와 기독교 교육적 돌봄)

  • Jeung-Gwan Lee
    • Journal of Christian Education in Korea
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    • v.72
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    • pp.49-70
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    • 2022
  • The purpose of this study is to suggest a response and solution through Christian educational care to the crisis and change of the era of low birth rate faced by Korean society and the Korean church. This study proposes to find an alternative to the biblical aspect of pregnancy, childbirth, and parenthood as God's blessing for the demographic cliff and low birth rate problem that have become a reality in Korean society and churches. Being a parent in an age of low birth rate is very difficult, but on the other hand, it gives happiness and joy. Being a parent is a blessing from God, and is the most important and valuable thing in life. However, modern society emphasizes the right and necessity to choose one's own parenthood status. In the nuclear family, the decrease in the number of children, and the development of child research, parents feel more responsibility and economic burden for raising children than ever before. Therefore, it is a reality that the number of people who delay becoming parents or voluntarily do not have children is gradually increasing. To improve the perception of becoming a parent due to a decrease in responsibility for raising children, it is necessary to shed light on marriage, pregnancy, childbirth, and childrearing from a Christian educational point of view. In addition, it is necessary to understand the recognition of being a parent and the characteristics of childbirth and rearing, and to analyze past and present value changes. This study will also discuss the causes of low birthrate and try to provide Christian educational care for childcare including solving the low birthrate problem.

Physio-mechanical and X-ray CT characterization of bentonite as sealing material in geological radioactive waste disposal

  • Melvin B. Diaz;Sang Seob Kim;Gyung Won Lee;Kwang Yeom Kim;Changsoo Lee;Jin-Seop Kim;Minseop Kim
    • Geomechanics and Engineering
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    • v.34 no.4
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    • pp.449-459
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    • 2023
  • The design and development of underground nuclear waste repositories should cover the performance evaluation of the different components such as the construction materials because the long term stability will depend on their response to the surrounding conditions. In South Korea, Gyeonju bentonite has been proposed as a candidate to be used as buffer and backfilling material, especially in the form of blocks to speed up the construction process. In this study, various cylindrical samples were prepared with different dry density and water content, and their physical and mechanical properties were analyzed and correlated with X-ray CT observations. The main objective was to characterize the samples and establish correlations for non-destructive estimation of physical and mechanical properties through the utilization of X-ray CT images. The results showed that the Uniaxial Compression Strength and the P-wave velocity have an increasing relationship with the dry density. Also, a higher water content increased the values of the measure parameters, especially for the P-wave velocity. The X-ray CT analysis indicated a clear relation between the mean CT value and the dry density, Uniaxial Compression Strength, and P-wave velocity. The effect of the higher water content was also captured by the mean CT value. Also, the relationship between the mean CT value and the dry density was used to plot CT dry densities using CT images only. Moreover, the histograms also provided information about the samples heterogeneity through the histograms' full width at half maximum values. Finally, the particle size and heterogeneity were also analyzed using the Madogram function. This function identified small particles in uniform samples and large particles in some samples as a result of poor mixing during preparation. Also, the μmax value correlated with the heterogeneity, and higher values represented samples with larger ranges of CT values or particle densities. These image-based tools have been shown to be useful on the non-destructive characterization of bentonite samples, and the establishment of correlations to obtain physical and mechanical parameters solely from CT images.

Development of Analysis Tool for Structural Behavior of Domestic Containment Building with Grouted Tendon (CANDU-type) (국내 부착식 텐던 격납건물(CANDU형)의 구조거동 분석 도구 개발)

  • Lee, Sang-Keun;Song, Young-Chul
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.5A
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    • pp.901-908
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    • 2006
  • The structural integrity of containment building in Nuclear Power Plants has to be verified by the ISI(In Service Inspection) because there are some variations on the structural behavior of it due to the change of the physical properties of concrete and tendon with the lapse of time. In this study, the program 'SAPONC-CANDU' which can monitor and analyze the structural behavior of the containment building with grouted tendon (CANDU-type, 'Wolsong unit-2, 3, and 4' in Korea) was developed. This program is based on the algorithm which can calculate the prediction values of the quantities of strain variation for the vibrating-wire strain gauges embedded into the concrete of the containment building under temperature and time dependent factors which are creep, shrinkage, and prestressing force. The readings of the strain gauges are used as input data for the operation of the program. And it finally provides graphically a prediction value, line and band of the quantity of strain variation for the respective strain gauges, therefore, it is thought that the site engineers are able to assess the structural integrity of the domestic containment building with grouted tendon with easy using this program.

China and global leadership (Китай и глобальное лидерство)

  • Mikheev, Vasily;Lukonin, Sergey;Ignatev, Sergei
    • Analyses & Alternatives
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    • v.1 no.2
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    • pp.31-43
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    • 2017
  • The article is devoted to the theoretical and practical analysis of Chinese global leadership. The concept of leadership is applied as a methodology, which involves identifying the main factors, such as strategic power, the attractiveness of political institutions, the ability to provide acceptable ideas and the presence of allies that contribute to a comprehensive analysis of the country's leadership potential. The authors also describe the relevance of Chinese global leadership and analyze its domestic, economic and international causes. Moreover, the ''Belt and Road'' initiative is defined as the main mechanism for providing the influence of China on the global level which is now being changed its quantitative component, namely the increasing attention to the security aspects of this initiative. In addition to that, it is important to note that China maintains its economic and political positions in Africa, Central Asia and South-East Asia. Africa has a special role in the Chinese ''Belt and Road'' initiative as a recipient of Chinese investments and a site for the deployment of China's naval facilities to protect the trade routes. On the regional level, China will strive to become a leader of the trade and economic processes in the Asia-Pacific region, the South China Sea and the North Korea nuclear program issues. The American factor in modern international relations, namely so-called "Trump factor", which means the U.S. withdrawal from the Trans-Pacific Partnership and the Paris Agreement, will cause demand for Chinese leadership in the Asia-Pacific region and in the world as well. However, in this case a number of questions arise: is China prepared for this? Is Beijing able to bear greater responsibility? Does China have the potential for this? The article concludes that China will not become global leaders in the next 20-30 years, because of internal (political reforms) and foreign policy reasons (doctrinal formulation of foreign policy initiatives, military-political and economic power, international posture and relations with other states). The authors believe that the implementation of Chinese leadership is possible not on the condition of confrontation between China and the United States, but on the establishing of constructive relations between these countries. The last meeting between Trump and Xi Jinping showed a trend for creating channels for dialogue between Beijing and Washington, which can become the basis for interaction. An important place in the work is given to the analysis of development and forecasting the evolution of Russian-Chinese and U.S.-China relations. As for Russia, Moscow should conduct a policy that will not allow it to become a ''junior partner'' of China.

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Radar-based rainfall prediction using generative adversarial network (적대적 생성 신경망을 이용한 레이더 기반 초단시간 강우예측)

  • Yoon, Seongsim;Shin, Hongjoon;Heo, Jae-Yeong
    • Journal of Korea Water Resources Association
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    • v.56 no.8
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    • pp.471-484
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    • 2023
  • Deep learning models based on generative adversarial neural networks are specialized in generating new information based on learned information. The deep generative models (DGMR) model developed by Google DeepMind is an generative adversarial neural network model that generates predictive radar images by learning complex patterns and relationships in large-scale radar image data. In this study, the DGMR model was trained using radar rainfall observation data from the Ministry of Environment, and rainfall prediction was performed using an generative adversarial neural network for a heavy rainfall case in August 2021, and the accuracy was compared with existing prediction techniques. The DGMR generally resembled the observed rainfall in terms of rainfall distribution in the first 60 minutes, but tended to predict a continuous development of rainfall in cases where strong rainfall occurred over the entire area. Statistical evaluation also showed that the DGMR method is an effective rainfall prediction method compared to other methods, with a critical success index of 0.57 to 0.79 and a mean absolute error of 0.57 to 1.36 mm in 1 hour advance prediction. However, the lack of diversity in the generated results sometimes reduces the prediction accuracy, so it is necessary to improve the diversity and to supplement it with rainfall data predicted by a physics-based numerical forecast model to improve the accuracy of the forecast for more than 2 hours in advance.

Indigo Naturalis in Inflammatory Bowel Disease: mechanisms of action and insights from clinical trials

  • Hyeonjin Kim;Soohyun Jeong;Sung Wook Kim;Hyung-Jin Kim;Dae Yong Kim;Tae Han Yook;Gabsik Yang
    • Journal of Pharmacopuncture
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    • v.27 no.2
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    • pp.59-69
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    • 2024
  • This study investigates the therapeutic potential of Indigo Naturalis (IN) in treating a Inflammatory Bowel Disease (IBD). The objective is to comprehensively examine the effects and pharmacological mechanisms of IN on IBD, assessing its potential as an novel treatment for IBD. Analysis of 11 selected papers is conducted to understand the effects of IN, focusing on compounds like indirubin, isatin, indigo, and tryptanthrin. This study evaluates their impact on Disease Activity Index (DAI) score, colon length, mucosal damage, and macrophage infiltration in Dextran Sulfate Sodium (DSS)-induced colitis mice. Additionally, It investigate into the anti-inflammatory mechanisms, including Aryl hydrocarbon Receptor (AhR) pathway activation, Nuclear Factor kappa B (NF-κB)/nod-like receptor family pyrin domain containing 3 (NLRP3)/Interleukin 1 beta (IL-1β) inhibition, and modulation of Toll-like receptor 4 (TLR4)/myeloid differentiation primary response 88 (MYD88)/NF-κB and Mitogen Activated Protein Kinase (MAPK) pathways. Immunomodulatory effects on T helper 17 (Th17)/regulatory T cell (Treg cell) balance and Glycogen synthase kinase-3 beta (GSK3-β) expression are also explored. Furthermore, the study addresses the role of IN in restoring intestinal microbiota diversity, reducing pathogenic bacteria, and increasing beneficial bacteria. The findings reveal that IN, particularly indirubin and indigo, demonstrates significant improvements in DAI score, colon length, mucosal damage, and macrophage infiltration in DSS-induced colitis mice. The anti-inflammatory effects are attributed to the activation of the AhR pathway, inhibition of inflammatory pathways, and modulation of immune responses. These results exhibit the potential of IN in IBD treatment. Notably, the restoration of intestinal microbiota diversity and balance further supports its efficacy. IN emerges as a promising and effective treatment for IBD, demonstrating anti-inflammatory effects and positive outcomes in preclinical studies. However, potential side effects necessitate further investigation for safe therapeutic development. The study underscores the need for future research to explore a broader range of active ingredients in IN to enhance therapeutic efficacy and safety.

A study on Korea's defense export expansion strategy - Focusing on Korea-Poland Defense Export Case - (한국의 방산수출 확대 전략 연구 - 한·폴란드 방산수출 사례를 중심으로 -)

  • Geum-Ryul Kim
    • Convergence Security Journal
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    • v.23 no.4
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    • pp.141-151
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    • 2023
  • Since the end of the Cold War in the 1990s, European countries have cut defense costs and reduced armaments as an era of peace without large-scale wars continues, and as a result, the West's defense industry base has gradually weakened. On the other hand, South Korea, the world's only divided country, was able to achieve high growth in the defense industry as a result of continuous arms strengthening in the face of North Korea's nuclear and missile threats. With the rapid increase in demand for conventional weapons systems and changes in the structure of the global defense market due to the Russia-Ukraine war, Korea's weapons system drew great attention as a large-scale defense export contract with Poland was signed in 2022. In 2023, K-Defense ranked ninth in the world's arms exports and aims to become the world's fourth-largest defense exporter by 2027. Therefore, this study analyzed the case of Korea-Poland defense exports to derive problems, and presented development strategies related to export revitalization of K-Defense, a national strategic industry. In order for the defense industry to become Korea's next growth engine, it is necessary to establish a defense organization, prepare government-level measures to protect defense industry technology, and expand military and security cooperation with allies linked to defense exports.