• Title/Summary/Keyword: Ns-2

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Rapid Synthesis of AgInS2/ZnS Core/Shell Nanoparticles and Their Luminescence Property

  • Lee, Seung Jae;Kim, Da Hea;Jung, Jongjin;Park, Joung Kyu
    • Rapid Communication in Photoscience
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    • v.4 no.2
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    • pp.45-47
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    • 2015
  • We have successfully synthesized $AgInS_2$ core and $AgInS_2$/ZnS core/shell nanoparticles by the sonochemical method. The ultrasonic based $AgInS_2$ and $AgInS_2$/ZnS nanoparticle synthesis can be utilized as a simple and rapid method. The $AgInS_2$/ZnS nanoparticles show the higher fluorescence intensity and quantum yield than $AgInS_2$ nanoparticles. Fluorescence wavelength of $AgInS_2$/ZnS shows blue shift from 635 nm to 610 nm against $AgInS_2$ because of reducing the defect sites and increasing spatial confinements. For the fluorescence lifetime, $AgInS_2$/ZnS (124.8 ns) has longer lifetime than $AgInS_2$ (54.8 ns).

Connecting the dots between SHP2 and glutamate receptors

  • Ryu, Hyun-Hee;Kim, Sun Yong;Lee, Yong-Seok
    • The Korean Journal of Physiology and Pharmacology
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    • v.24 no.2
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    • pp.129-135
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    • 2020
  • SHP2 is an unusual protein phosphatase that functions as an activator for several signaling pathways, including the RAS pathway, while most other phosphatases suppress their downstream signaling cascades. The physiological and pathophysiological roles of SHP2 have been extensively studied in the field of cancer research. Mutations in the PTPN11 gene which encodes SHP2 are also highly associated with developmental disorders, such as Noonan syndrome (NS), and cognitive deficits including learning disabilities are common among NS patients. However, the molecular and cellular mechanism by which SHP2 is involved in cognitive functions is not well understood. Recent studies using SHP2 mutant mice or pharmacological inhibitors have shown that SHP2 plays critical role in learning and memory and synaptic plasticity. Here, we review the recent studies demonstrating that SHP2 is involved in synaptic plasticity, and learning and memory, by the regulation of the expression and/or function of glutamate receptors. We suggest that each cell type may have distinct paths connecting the dots between SHP2 and glutamate receptors, and these paths may also change with aging.

Output characteristics of intracavity frequency doubling of laser-diode end-pumped Nd:S-VAP laser (반도체레이저 단면여기 Nd:S-VAP 레이저의 내부공진기 제2고조파 출력 특성)

  • 박준학
    • Korean Journal of Optics and Photonics
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    • v.11 no.4
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    • pp.294-298
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    • 2000
  • The output characteristics of intracavity frequency doubling of laser-diode end-pumped Nd:S-VAP laser were investigated. Nd:S-VAP is suitable for a microchip laser medium, which has a low threshold property because of a very high value of the stimulated emission cross-section and lifetime product. The threshold energy measured was 81 J.ll. The second harmonic output energy measured was $126\mu\textrm{J}$at a pump energy of $2\mu\textrm{J}$. We described for intracavity frequency doubling by using theoretical calculations. Q-switched second harmonic energy measured was $15\mu\textrm{J}$per pulse with a pulse-width of 26 ns. at a pump energy of 2 mJ and an $M^2$ of 1.47 represented a good beam quality. ality.

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Performance Evaluation of Component Detectors of Double-scattering Compton Camera (이중 산란형 컴프턴 카메라 구성 검출기 성능 평가)

  • Seo, Hee;Park, Jin-Hyung;Kim, Chan-Hyeong;Lee, Ju-Hahn;Lee, Chun-Sik;Lee, Jae-Sung
    • Journal of Radiation Protection and Research
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    • v.35 no.2
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    • pp.69-76
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    • 2010
  • Prototype double-scattering Compton camera, which consists of three gamma-ray detectors, that is, two double-sided silicon strip detectors (DSSDs) as scatterer detectors and a NaI(Tl) scintillation detector as an absorber detector, could provide high imaging resolution with a compact system. In the present study, the energy resolution and the timing resolution of component detectors were measured, and the parameters affecting the energy resolution of the DSSD were examined in terms of equivalent noise charge (ENC). The energy resolutions of the DSSD-1 and DSSD-2 were, in average, $25.2keV{\pm}0.8keV$ FWHM and $31.8keV{\pm}4.6keV$ FWHM at the 59.5 keV peak of $^{241}Am$, respectively. The timing resolutions of the DSSD and NaI(Tl) scintillation detector were 57.25 ns FWHM and 7.98 ns FWHM, respectively. In addition, the Compton image was obtained for a point-like $^{137}Cs$ gamma source with double-scattering Compton camera. From the present experiment, the imaging resolution of 8.4 mm FWHM (angular resolution of $8.1^{\circ}$ FWHM), and the imaging sensitivity of $1.5{\times}10^{-7}$ (intrinsic efficiency of $1.9{\times}10^{-6}$) were obtained.

Desorption Characteristics and Bioavailability of Zn to Earthworm in Mine Tailings (광미내 Zn의 탈착 특성과 지렁이에 대한 생이용성)

  • Oh, Sang-Hwa;Shin, Won-Sik
    • Journal of Soil and Groundwater Environment
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    • v.16 no.4
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    • pp.38-52
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    • 2011
  • Sorption and sequential desorption experiments were conducted for Zn using a natural soil (NS) in background status by aging (1, 30 and 100 days). The sorption isotherm showed that Zn had high sorption capacity but low sorption affinity in NS. Sequential desorption was biphasic with appreciable amount of sorbed Zn residing in the desorption-resistant fraction after several desorption steps. The biphasic desorption behavior of Zn was characterized by a biphasic desorption model that includes a linear term to represent labile or easily-desorbing fraction and a Langmuirian-type term to represent desorption-resistant fraction. The biphasic desorption model indicated that the size of the maximum capacity of desorption-resistant fraction ($q^{irr}_{max}$) increased with aging in NS. Desorption kinetics and desorption-resistance of Zn in the soils collected from mine tailings (MA, MB and MC collected from surface, subsurface soils and mine waste, respectively) were investigated and compared to the bioavailability to earthworm (Eisenia fetida). Desorption kinetic data of Zn were fitted to several desorption kinetic models. The ratio ($q_{e,d}/q_0$) of remaining Zn at desorption equilibrium ($q_{e,d}$) to initial sorbed concentration ($q_0$) was in the range of 0.53~0.90 in the mine tailings which was higher than that in NS, except MA. The sequential desorption from the mine tailings with 0.01M Na$NO_3$ and 0.01M $CaCl_2$ showed that appreciable amounts of Zn are resistant to desorption due to aging or sequestration. The SM&T (Standard Measurements and Testing Programme of European Union) analysis showed that the sum of oxidizable (Step III) and residual (Step IV) fractions of Zn was linearly related with its desorption-resistance ($q^{irr}_{max}$) determined by the sequential desorption with 0.01M Na$NO_3$ ($R^2$= 0.9998) and 0.01M $CaCl_2$ ($R^2$= 0.8580). The earthworm uptake of Zn and the desorbed amount of Zn ($q_{desorbed}$ = $q_0-q_{e,d}$) in MB soil were also linearly related ($R^2$ = 0.899). Our results implicate that the ecological risk assessment of heavy metals would be possible considering the relation between desorption behaviors and bioavailability to earthworm.

Video Replay by Frame Receive Order Relocation Method in the Wire and Wireless Network (유무선 네트워크에서 프레임 수신 순서 재할당 방법을 사용한 동영상 재생)

  • Kang, Dong-Jin;Kim, Dong-Hoi
    • Journal of Digital Contents Society
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    • v.17 no.3
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    • pp.135-142
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    • 2016
  • When video service is performed in simulation using NS-2(Network Simulation-2), the video replay is performed as the received frame order. In the existing video replay method based on the received frame order, as the frame orders of receiver and transmitter are different, the receiver buffer does not have the effect that the packets between the frames of transmitter buffer holds a regular size and packet dense and sparsity phenomenon in the receiver buffer is made by the irregular packet size due to the unpredictable reversed order of received partial frames. The above dense and sparsity phenomenon increases the probability of buffer overflow and underflow generation. To prevent these problems, the proposed frame receive order relocation method adds an extra replay buffer which rearranges the order of receive frame as the order of transmit frame, so it has the effect that the packets between the transmit frames keeps a regular size. Through the simulation using NS-2 and JSVM(Joint Scalable Video Model), the generation number of buffer overflow and underflow, and PSNR(Required Peak Signal to Noise Ratio) performance between the existing method and proposed method were compared. As a result, it was found that the proposed method would have better performance than the existing method.

General Linear Group over a Ring of Integers of Modulo k

  • Han, Juncheol
    • Kyungpook Mathematical Journal
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    • v.46 no.2
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    • pp.255-260
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    • 2006
  • Let $m$ and $k$ be any positive integers, let $\mathbb{Z}_k$ the ring of integers of modulo $k$, let $G_m(\mathbb{Z}_k)$ the group of all $m$ by $m$ nonsingular matrices over $\mathbb{Z}_k$ and let ${\phi}_m(k)$ the order of $G_m(\mathbb{Z}_k)$. In this paper, ${\phi}_m(k)$ can be computed by the following investigation: First, for any relatively prime positive integers $s$ and $t$, $G_m(\mathbb{Z}_{st})$ is isomorphic to $G_m(\mathbb{Z}_s){\times}G_m(\mathbb{Z}_t)$. Secondly, for any positive integer $n$ and any prime $p$, ${\phi}_m(p^n)=p^{m^2}{\cdot}{\phi}_m(p^{n-1})=p{^{2m}}^2{\cdot}{\phi}_m(p^{n-2})={\cdots}=p^{{(n-1)m}^2}{\cdot}{\phi}_m(p)$, and so ${\phi}_m(k)={\phi}_m(p_1^n1){\cdot}{\phi}_m(p_2^{n2}){\cdots}{\phi}_m(p_s^{ns})$ for the prime factorization of $k$, $k=p_1^{n1}{\cdot}p_2^{n2}{\cdots}p_s^{ns}$.

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Transmission Performance of Application Service Traffic on MANET with IDS (IDS가 있는 MANET에서 응용 서비스 트래픽의 전송 성능)

  • Kim, Young-Dong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.05a
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    • pp.584-587
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    • 2012
  • MANET, which can be constructed with only terminal devices, has structural advantages of ease installation and operation, also has environmental change of rapid supply of smart phone, it's usage can be extended to application area likes as emergency communication, leasure, exploration and investigations. But, as one characteristic of MANET, no use of communicaton infrastructure caused disadvantage of weakness for information intrusion which is frequently occurred, nowadays. In this paper, the effects of IDS(Intrusion Detection System), one of defence tools for information intrusion, is analyzed for transmission performance. Blackhole attack is assumed as a type of intrusion, MANET defence with IDS from intrusions. Computer simulation based on NS-2 used for performance measurement. In this paper, performance measurement is done for application service to analyze application level effects of IDS. VoIP service is used as application service.

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Induction of P3NS1 Myeloma Cell Death and Cell Cycle Arrest by Simvastatin and/or γ-Radiation

  • Abdelrahman, Ibrahim Y;Helwa, Reham;Elkashef, Hausein;Hassan, Nagwa HA
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.7103-7110
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    • 2015
  • The present study was conducted to investigate the effect of ${\gamma}$-radiation alone or combined with a cytotoxic drug, simvastatin, on viability and cell cycling of a myeloma cell line. P3NS1 myeloma cells were treated with the selected dose of simvastatin ($0.1{\mu}M/l$) 24 hours prior to ${\gamma}$-irradiation (0.25, 0.5 and 1Gy). The cell viability, induction of apoptosis, cell death, cell cycling, generation of ROS, and expression of P53, Bax, Bcl2, caspase3, PARP1 and Fas genes were estimated. The results indicated that simvastatin ($0.1{\mu}M/l$) treatment for 24 hours prior to ${\gamma}$-irradiation increased cell death to 37.5% as compared to 4.81% by radiation (0.5Gy) alone. It was found that simvastatin treatment before irradiation caused arrest of cells in G0/G1 and G2/M phases as assessed using flow cytometry. Interestingly, simvastatin treatment of P3NS1 cells increased the intracellular ROS production and decreased antioxidant enzyme activity with increased P53, Bax and Caspase3 gene expression while that of Bcl2 was decreased. Consequently, our results indicated that pre-treatment with simvastatin increased radio sensitivity of myeloma tumor cells in addition to apoptotic effects through an intrinsic mitochondrial pathway.