• Nuclear Engineering and Technology
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• v.55 no.2
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• pp.655-668
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• 2023

In radiography, an antiscatter grid is a well-known device for eliminating unexpected x-ray scatter. We investigate a new stationary grid artifact suppression method based on a nonsubsampled contourlet transform (NSCT) incorporated with Gaussian band-pass filtering. The proposed method has an advantage that extracts the Moiré components while minimizing the loss of image information and apply the prior information of Moiré component positions in multi-decomposition sub-band images. We implemented the proposed algorithm and performed a simulation and an experiment to demonstrate its viability. We did this experiment using an x-ray tube (M-113T, Varian, focal spot size: 0.1 mm), a flat-panel detector (ROSE-M Sensor, Aspenstate, pixel dimension: 3032 × 3800 pixels, pixel size: 0.076 mm), and carbon graphite-interspaced grids (JPI Healthcare, 18 cm × 24 cm, line density: 103 LP/inch and 150 LP/inch, ratio: 5:1, focal distance: 65 cm). Our results indicate that the proposed method successfully suppressed grid artifacts by reducing them without either reducing the spatial resolution or causing negative side effects. Consequently, we anticipate that the proposed method can improve image acquisition in a stationary grid x-ray system as well as in extended x-ray imaging.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.432-432
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• 2021

우리나라는 대부분의 에너지 공급을 해외에 의존하고 있는 실정이다. 산업통상자원부와 에너지경제연구원에서 발간하는 2018년 에너지통계연보(에너지경제연구원과 산업통상자원부, 2018)에 실린 2010년부터 2017년까지의 에너지수급 균형을 보면 원유, 천연가스, 석탄, 우라늄 등 평균 95.4%의 에너지를 수입하고 있는 실정이다. 수력 및 신재생에너지의 경우 기후변화에 대응하는 수단 그리고 정부의 저탄소에너지 전환 정책으로 인정받아 상대적으로 낮은 에너지 경제성에도 불구하고 꾸준히 보급되고 있다. 우리나라뿐만 아니라 독일, 프랑스, 영국, 중국 그리고 인도와 같은 세계 주요 국가들이 친환경 에너지 정책을 주도함에 따라 향후 신재생에너지의 공급 규모는 크게 확대될 것으로 전망된다. 중력 물 보텍스 마이크로 수력 발전 시스템은 시스템의 상하류부의 수두(hydraulic head) 차에 의해 저류조(basin)에서 발생되는 물의 보텍스 즉 소용돌이(whirlpool)를 이용하여 임펠러(impeller)를 회전시켜 전기에너지를 생산하는 친환경적 재생에너지의 일종이다. 또한, 시스템으로 유입되는 물은 전기에너지 생산을 위한 임펠러를 통과한 후 다시 하천으로 방류되므로 하천 수의 손실 그리고 하천의 물길도 거의 교란 시키지 않는다. 4가구 정도의 연간 가정용 전기 요구량인 12와 15kW 사이의 전기에너지를 생산하기 위해서는 발전시스템의 상류와 하류의 수두차가 단지 1.5에서 1.7m 이하이면 충분한 것으로 알려져 있다. 본 연구에서는 중력 물 보텍스 친환경 마이크로 발전 시스템을 구성하는 저류조(basin)에 대해 최대 발전효율을 발생시키기에 최적인 기하학적 형태를 도출하는 것이며, 이를 위해 저류조의 cone angle에 따른 다양한 저류조 직경 및 물 보텍스 생성을 위한 저류조 형태의 변화, 유입수로와 저류조와의 각도인 notch angle의 변화, 유입부 폭과 유출부 직경, 유입수로의 길이 그리고 유입수로에서의 초기수심과 같은 기하학적 매개변수를 변화시켜 모의를 수행하였다.

• Journal of Digestive Cancer Research
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• v.4 no.1
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• pp.1-9
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• 2016

The abundance of multi-drug resistance ATPase binding cassette and deranged self-renewal pathways shown in cancer stem cells (CSCs) played a crucial role in tumorigenesis, tumor resistance, tumor recurrence, and tumor metastasis. Therefore, elucidation of CSCs biology can improve diagnosis, enable targeted treatment, and guide the follow up of GI cancer patients. In order to achieve chemoquiescence, seizing cancer through complete ablation of CSCs, CSCs are rational targets for the design of interventions that will enhance responsiveness to traditional therapeutic strategies and contribute in the prevention of local recurrence as well as metastasis. However, current cancer treatment strategies fail to either detect or differentiate the CSCs from their non-tumorigenic progenies mostly due to the absence of specific biomarkers and potent agents to kill CSCs. Recent advances in knowledge of CSCs enable to produce several candidates to ablate CSCs in gastrointestinal (GI) cancers, especially cancers originated from inflammation-driven mutagenesis such as Barrett's esophagus (BE), Helicobacter pylori-associated gastric cancer, and colitis-associated cancer (CAC). Our research teams elucidated through revisiting old drugs that proton pump inhibitor (PPI) and potassium competitive acid blocker (p-CAB) beyond authentic acid suppression, chloroquine for autophage inhibition, sonic hedgehog (SHH) inhibitors, and Wnt/β-catenin/NOTCH inhibitor can ablate CSCs specifically and efficiently. Furthermore, nanoformulations of these molecules could provide an additional advantage for more selective targeting of the pathways existing in CSCs just like current molecular targeted therapeutics and sustained action, while normal stem cells intact. In this review article, the novel approach specifically to ablate CSCs existing in GI cancers will be introduced with the introduction of explored mode of action.

• The korean journal of orthodontics
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• v.32 no.5 s.94
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• pp.313-325
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• 2002

Three-dimensional CT imaging is efficient in examining specific structures in the craniofacial area by reproducing actual measurements through minimization of errors from patient movement and image magnification. Due to the rapid development of digital image technology and the expansion of treatment range a need for developing three -dimensional analysis has become urgent. Therefore the purpose of this study was to evaluate the percentage of error and magnification of three-dimensional CT using a dried skull and Vworks $program^{TM}$ (Cybermed Inc., Seoul, Korea) and also to obtain landmarks that are easy to designate and reproduce in three-dimensional images using the Vmorph-proto $program^{TM}$ (Cybermed Inc., Seoul, Korea). The following conclusions were obtained, 1. In the comparison of actual measurements from the dried skull and the three-dimensional image obtained from the Vworks program, the mean error was 0.99mm and the magnification was 1.04%. 2. Clinically useful hard tissue landmarks from three-dimensional images were Supraorbitale, Lateral orbital margin, Infraorbitale, Nasion, ANS, A point, Zygomaticomaxilla, Upper incisor, Lower incisor, B point, pogonion, Menton, PNS, Condylar inner margin, Condylar outer margin, Porion, Condylion, Gonionl, Gonion2, Gonion3, Sigmoid notch and Basion. 3. Clinically useful soft tissue landmarks from three-dimensional images were Endocanthion, Exocanthion, Soft tissue Nasion, Pronasale, Alare lateralis, Upper nostril point, Lower nostril point, Subnasale, Upper lip point, Cheilion, Stomion, Lower lip center, Soft tissue B, Pogonion, Menton and Preaurale. The Vworks program can be considered a clinically efficient tool to produce and measure three-dimensional images. Most of the hard and soft tissue landmarks proposed above are anatomically important points which are also easily reproducible and designated. These landmarks can be beneficial in three-dimensional diagnosis and the prediction of changes before and after surgery.

• Korean Journal of Soil Science and Fertilizer
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• v.31 no.3
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• pp.211-215
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• 1998

Soil loss and runoff were investigated in a small watershed located in Sangeo-ri, Yeoju-eup, Yeoju-gun, Kyonggi-do. The watershed with the area of 35 ha consists of forest, grassland, uplands and mulberry. V-notch type water tank. flow-meter, automatic water sampler and rain gauge were installed at the main outlet stream. Out of $1.037.9Mg\;35ha^{-1}$ of total annual rainfall. 17.9% was lost via run-off. The total amount of soil eroded was $152.2Mg\;35ha^{-1}$, of which $78.6Mg\;35ha^{-1}$ was suspended load and $73.6Mg\;35ha^{-1}$ ha was sediment load. The soil losses under different land uses were $16.02Mg\;ha^{-1}$ for upland annual Crops. $2.69Mg\;ha^{-1}$ for mulberry field, $0.58Mg\;ha^{-1}$ for grassland and $0.55Mg\;ha^{-1}$ for forest. The predicted soil loss by Universal Soil Loss Equation was approximately 20% underestimated in forest, grassland and uplands, and 32% underestimated in mulberry field.

• 대한공업교육학회지
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• v.31 no.1
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• pp.200-210
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• 2006

This C-ring test, normally employed for evaluating susceptibility to stress-corrosion cracking, was determined to be a suitable small scale test to evaluate PWHT(Post-Weld Heat Treatment) cracking susceptibility. This test is possible to incorporate an actual weld, to introduce a notch into the coarse grained HAZ(Heat Affected Zone), to load the coarse grained HAZ any level of stress ad, most importantly, since the C-ring is an approximately constant strain type test, the stress decreases with time at temperature in a manner similar to that of an actual steel weldment. The procedure employed in making the C-ring was presented in the experimental procedure section, however, several points deserve further discussion. The walls of the weld groove are made along radial lines form the center of th var in order to obtain an HAZ which is oriented perpendicular to the walls of the machined C-ring. Therefore, the plane of maximum stress will be aligned through the HAZ and, therefore, crack propagation will not be forced to deviate form the plane of maximum stress in order to remain in the coarse grained HAZ as is the case with the Y groove test.

• Restorative Dentistry and Endodontics
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• v.18 no.1
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• pp.1-26
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• 1993

The purpose of this study was to investigate the effect of acid etching on the surface appearance and fracture toughness of five glass ionomer cements. Five kinds of commercially available glass ionomer cements including chemical curing filling type, chemical curing lining type, chemical curing metal reinforced type, light curing tilling type and light curing lining type were used for this study. The specimens for SEM study were fabricated by treating each glass ionomer cement with either visible light curing or self curing after being inserted into a rubber mold (diameter 4mm, depth 1mm). Some of the specimens were etched with 37% phosphoric acid for 0, 15, 30, 60, go seconds, at 5 minutes, 1 hour and 1 day after mixing of powder and liquid. Unetched ones comprised the control group and the others were the experimental groups. The surface texture was examined by using scanning electron microscope at 20 kV. (S-2300, Hitachi Co., Japan). The specimens for fracture toughness were fabricated by curing of each glass ionomer cement previously inserted into a metal mold for the single edge notch specimen according to the ASTME399. They were subjected to a three-point bend test after etching for 0, 30, 60, and 90 seconds at 5 minutes-, 1 hour-and 1 day-lapse after the fabrication of the specimens. The plane strain fracture toughness ($K_{IC}$) was determined by three-point bend test which was conducted with cross-head speed of 0.5 mm/min using Instron universal testing machine (Model No. 1122) following seven days storage of the etched specimens under $37^{\circ}C$, 100% humidity condition. Following conclusions were drawn. 1. In unetched control group, crack was present, but the surface was generally smooth. 2. Deterioration of the surface appearance such as serious dissolving of gel matrix and loss of glass particles occured as the etching time was increased beyond 15 s following Immediate etching of chemical curing type of glass ionomer cements. 3. Etching after 1 h, and 1 d reduced surface damage, 15 s, and 30s etch gave rough surface appearance without loss of glass particle of chemical curing type of glass ionomer cements. 4. Light curing type glass ionomer cement was etched by acid, but there was no difference in surface appearances according to various waiting periods. 5. It was found that the value of plane stram fracture toughness of glass ionomer cements was highest in the light curing filling type as $1.79\;MNm^{-1.5}$ followed by the light curing lining type, chemical curing metal reinforced type, chemical curing filling type and chemical curing lining type. 6. The value of plane stram fracture toughness of the chemical curing lining type glass ionomer cement etched after 5 minutes was lower than those of the cement etched after 1 hour or day or unetched (P < 0.05). 7. Light curing glass ionomer cement showed Irregular fractured surface and chemical curing cement showed smooth fractured surface.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.21 no.2
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• pp.165-179
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• 1991

This study was performed to understand the irradiation effects on the mandibular condyle and mandibular growth in developing white rats. Forty eight white male rats of the Sprague-Dawley strain aged 4 weeks, were devided into two groups; control group and experimental group. A single target dose of l0Gy of radiation was given to the mandibular condylar area and the observations of the photo analysis, radiologic, histopathologic and immunohistochemical study revealed as follows; 1. Animals killed one week after irradiation showed lesser increase in body weights, no difference in photo analysis and decreased thickness of cartilagenous layers of the condyle than the control group. 2. Two weeks after irradiation the weight increases were almost same in both irradiated and control groups and in photo analysis, the distance from Mental Foramen to Incisal tip (Mf-It) was longer than the controls. Repair processes were taken place in irradiated group, but the cartilagenous layers were thinner than the controls. 3. By the third week after exposure further repair was seen in the trabeculae and the distance from Condylion to Mandibular plane (Cd-Cd') was longer than the controls and the weight increases were almost same as the controls. 4. At 4 weeks after irradiation the cells of proliferating zone repaired to almost normal findings, but the cartilagenous cell layers were still thinner than the control animals. In photo analysis, the distances from Menton to Anterior Notch (Me-An), from First Molar to Mandibular plane (Fm-Fm') were shorter and the weight increases were lesser than the controls. 5. In the S-100 antibody, the positive cells were increased in number, but decreased reactivities were seen at the proliferating zone of the irradiated groups. In the Monoclonal Anti-Proteoglycan antibody and Type Ⅰ collagen antibody, the irradiated groups showed little decreased number of positive cells and in the Type Ⅱ collagen antibody, the differences between irradiated and control groups were undetectable in immunohistochemical study.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.4 s.175
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• pp.1055-1064
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• 2000

First, various specimen geometries, namely, coupon type, waisted type and dog-bone type, were examined to determine appropriate fatigue specimen of thermoplastic composite material AS4/PEEK and the n, fatigue strength of smooth and notched specimens of AS4/PEEK [-45/0/+45/90]2s was investigated. Fatigue tests were performed under load controlled condition at a stress ratio of 0. 1 at a frequency of 5Hz. Stiffness degradation of specimens with fatigue cycling was monitored using an automated unloading compliance technique. The waisted type specimen is found appropriate for smooth fatigue specimen geometry of AS4/PEEK. As for the effect of stress concentration, it is found that fatigue strength is higher for a 2mm-diameter hole notched specimen than a 5mm-diameter one. Fatigue notch factor decreases with the increase of fatigue life. These results are far different from the trend of fatigue strength of metallic materials. The stiffness variation of smooth specimen was only 4% at maximum until final fracture. On the other hand, the stiffness of hole notched specimen was reduced by 45% at maximum. Notched fatigue strength was compared between thermoplastic composite AS4/PEEK and thermosetting composite Graphite/Epoxy. In long-life fatigue (>104), the AS4/PEEK composite shows superior fatigue strength, but in short-life fatigue, the fatigue strength of the Graphite/Epoxy composite is nearly equal or somewhat higher than that of the AS4/PEEK composite.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.6
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• pp.913-922
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• 1987

In this paper the solidification phenomena at the molten pool has been modeled and simulated in terms with the one dimensional unsteady-state heat transfer of the solid and molten phase and the pressure distribution in the solid phase for the twin-roller continuous casting of Sn-15% Pb. The further purpose of this study was to effectively analyze the thermal and mechanical deformation of roll applying the results of the heat transfer and the pressure distribution to the boundary conditions. The strip thickness of rapidly solidified metallic strip decreases with increasing angular velocity of the roller and with increasing initial roll gap. For this reason the roll spacing and angular velocity of the rolls are considered to be main variables. The recommended optimal casting regimes for continuous strip dimensions is near 0.8mm-1.0mm in thickness at the given angular velocity .omega.=2.0 rad/sec. Results of the experiment using Sn-15% Pb are compared with model predictions. The calculated roll deformation has been in good agreement with the observed value of roll deformatiion. All the deformation. All the deformation of the roller is within the elastic range, the plastic yielding are not occured. However, these elastic stresses are sufficient to take place of the shortened roller life by the thermal fatigue and a notch fatigue. The higher cooling rates were obtained by a twin-roller quenching technique. Also the quenched microstructure of the rapidly solidified shell was verified.