• Journal of the East Asian Society of Dietary Life
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• v.23 no.1
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• pp.44-52
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• 2013

This study investigated hepatic functional improvement and anti-fibrotic effects of water extracts of black tea. Male Sprague-Dawley rats were divided into four groups (normal, control, and two experimental subgroups: Ba, Bb) and observed for 3 weeks. Liver fibrosis in rats developed from carbon tetrachloride ($CCl_4$) administration, except for the normal group. Except for the normal and control group, the two experimental subgroups were fed water extracts of black tea. The food efficiency ratio significantly increased in the experimental group compared to the control group. The experimental group had a significantly lower liver weight compared to the control group. The ratio of liver weight to body weight was significantly lower in the experimental group than the control group. The levels of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, blood urea nitrogen, and low-density lipoprotein-cholesterol in serum significantly decreased in the experimental group compared to the control group. The values of hydroxyproline and malondialdehyde in liver were even lower in the experimental group than the control group. In observations on liver histology, weaker inflammation and fibrosis were observed in the experimental group compared to the control group. In conclusion, water extracts of black tea help hepatic cells keep their functions, restraining and protecting the liver from impairments caused by $CCl_4$ administration, and can be effective as anti-fibrotic agents.

• Journal of the Society of Naval Architects of Korea
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• v.51 no.6
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• pp.489-494
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• 2014

Estimation of correct ice load under various operating conditions is important during the design and the operation stages of an icebreaker. Normal operating conditions are expected from the official field ice trials and also from general ice transit action. In this paper ice load for the Korean icebreaking research vessel, ARAON, under normal operating condition, is discussed. Published ice load data from full-scale sea trials of six icebreakers were analysed to derive an empirical ice load prediction formula. The IBRV ARAON had sea ice trials during 2010 and 2012 summer season. Strain gauge signal were recorded during her icebreaking voyage and the measured strain data were converted to the equivalent hull stress values. The effect of ARAON's speed in ice and the hull stresses are investigated. By comparing the empirical formula and ice load calculation based von measured data, it is recommended to use the empirical ice load estimation formula for the initial design stage.

• The Journal of Korean Physical Therapy
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• v.10 no.1
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• pp.127-138
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• 1998

This study was carried out tn invstigate and compare biomechanical characteristics during free speed gait in hemiplegic patients after stroke who took therapeutic exercise by analyzing kinematic and kinetic data in the sagital plane and electromyographic data. Six patients($41\~69$ years old) and age-matched six volunteers in good health(51-61 years old) wire studied. The patients were sorted into two groups, depending on their self-speed of walking : fast speed group(3 patients) and slow speed group(3 patients). The results were as fellows. : 1. In spatio-temparal parameters, affected and unaffected side of fast group showed symetry but blew group showed asymetry of single limb support, opposite foot contact and stance phase (p<0.05). Compared with normal group, patient group showed slower velocity, shoter stride length and longer double limb support (p<0.05). 2. In the pelvic anterior tilt, patient group showed lower valued than normal group. It. In the ground reaction force-vertical force, fast group showed similar double peak gragh compared with normal group, butvslow group showed lower values without double peak (p<0.05).

• Communications for Statistical Applications and Methods
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• v.14 no.1
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• pp.169-182
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• 2007

Receive operating characteristic (ROC) approach can be employed to rank candidate genes from a microarray experiment, in particular, for the biomarker development with the purpose of population screening of a cancer. In the cancer microarray experiment based on n patients the researcher often wants to compare the tumor tissue with the normal tissue within the same individual using a common reference RNA. Ideally, this experiment produces n pairs of microarray data. However, it is often the case that there are missing values either in the normal or tumor tissue data. Practically, we have $n_1$ pairs of complete observations, $n_2$ "normal only" and $n_3$ "tumor only" data for the microarray. We refer to this data set as a mixed data set. We develop a ROC approach on the mixed data set to rank candidate genes for the biomarker development for the colorectal cancer screening. It turns out that the correlation between two ranks in terms of ROC and t statistics based on the top 50 genes of ROC rank is less than 0.6. This result indicates that employing a right approach of ranking candidate genes for the biomarker development is important for the allocation of resources.

• Phonetics and Speech Sciences
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• v.8 no.4
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• pp.89-95
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• 2016

The purpose of this work is to analyze and synthesize the pseudo-periodicity of voice using a source model. A speech signal has periodic characteristics; however, it is not completely periodic. While periodicity contributes significantly to the production of prosody, emotional status, etc., pseudo-periodicity contributes to the distinctions between normal and abnormal status, the naturalness of normal speech, etc. Measurement of pseudo-periodicity is typically performed through parameters such as jitter and shimmer. For studying the pseudo-periodic nature of voice in a controlled environment, through collected natural voice, we can only observe the distributions of the parameters, which are limited by the size of collected data. If we can generate voice samples in a controlled manner, experiments that are more diverse can be conducted. In this study, the probability distributions of vowel pitch variation are obtained from the speech signal. Based on the probability distribution of vocal folds, pulses with a designated jitter value are synthesized. Then, the target and re-analyzed jitter values are compared to check the validity of the method. It was found that the jitter synthesis method is useful for normal voice synthesis.

• The Journal of Korean Physical Therapy
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• v.32 no.5
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• pp.302-306
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• 2020

Purpose: The purpose of this study was to investigate comparisons of vastus medialis (VMO) and vastus lateralis (VL) muscle activities according to different heights during drop landing in flatfooted adults. Methods: Fifteen subjects with a flat foot arch and 15 subjects with a normal feet arch were participated. Subjects performed a double limb drop landing task from 20, 40, and 60 cm heights. Surface electromyography was used to measure the muscle activities of the VMO and VL during drop landing. Results: There were significant differences of muscle activities in the VMO, VL, and the VMO and VL ratio between groups. The electromyography values of VMO, VL, and the VMO and VL ratio in the normal group were significantly greater than in the flat foot group, and muscle activities and the VMO and VL ratio significantly increased with landing heights in the both groups. Conclusion: Our results indicated that muscle activity patterns of VOM and VL in the flat foot group were lower at heights than in the normal group, so calf tightness was negative effects on balance and gait ability, so assessment of muscle activation patterns in the knee extensors should be considered during exercise and treatment of flat feet.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.25 no.2
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• pp.61-68
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• 2011

The circuit breaker of power distribution board is essential part for the protection of electrical disaster from load short, trouble of power system. For the normal operation of circuit breaker, trip coil of the circuit breaker can cut the mechanical contact of circuit breaker from the detection of power system troubles. This paper presents a design and experimental results of trip coil fault detection system for the real time monitoring of the circuit breaker. The designed system is consisted by the trip coil fault detector which is connected to the each circuit breaker and remote monitoring unit. The trip coil fault detector can detect the impedance and operating voltage of the trip coil, and the detected values are compared with the normal state. And the remote monitoring unit can be connected to the 32 channels of trip coil fault detectors by serial communication. From the designed system, the fault and normal states of the trip coil can be remotely monitored in real time. The designed system is verified by the practical circuit breaker of power distribution board. And the results shows the effectiveness of the designed system.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.167-167
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• 1996

A series of 6-[(N-Halophenyl)amino] -7-Bromo-5,8-quinolinediones (BQs) newly synthesized were tested for antifungal activities, in vitro, against Candida sp., Aspergillus niger and Trichophyton mentagrophytes. The MIC values were determined by the twofold dilution method. Among these derivatives, BQ4 and 7 showed more potent antifungal activities than fluconazole and ketoconazole. BQ 4 and 7 were compared with fluconazole in the treatment of established systemic infections with Candida albicans in normal rats. Intraperitoneally administered BQs for 7 days and 14 days reduced Candida albicans colony count in kidneys and livers as well as fluconazole. The therapeutic potential of BQs has been assessed by evaluating their activities (survival rate) against systemic infections in normal mice with Candida albicans. These compounds, particularly showed activities comparable with fluconazole. BQ4 and 7 had about EO$\_$50/, 0.05, 0.06mg/kg but fluconazole had ED$\_$50/, 6.0mg/kg respectively.

• Proceedings of the Korea Concrete Institute Conference
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• 1994.10a
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• pp.356-361
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• 1994

From the previous experimental test results, it has shown that shear that shear strength in lightweight concrete beams was about 85% on that in normal concrete beams. It is speculated that shear connectors in composite beams of steel and lightweight concrete associated with the longitudinal shear strength decrease more in strength than those in normal concrete. So this paper, as a study on strength of shear connectors in composite beams of steel and lightweight concrete slabs, has a purpose to compare the strength formula resulted from the push-out test of thirteen solid slab and four deck Plate slab with the established ones, and then to suggest a proper strength formula of the shear connectors. The established strength formula of the shear connectors is prescribed for $P_ps = 0.50A_s . \sqrt{f_C . E_C}$by AISC coed, but from the experimental test results the strength values of the shear connectors in lightweignt concrete slabs shows about 70% on those of the shear connectors in normal concrete slabs by AISC code. Therefore, as a strength formula this paper suggests to multiply the established strength formula by reduction factor$(\varphi=0.7)$.

• Proceedings of the Korean Environmental Health Society Conference
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• 2005.06a
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• pp.333-336
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• 2005

32 Volatile organic compounds(VOCs) were measured by thermal desorption/gas chrornatography/mass spectrometry in normal houses, new and sick houses. The sum concentrations of aromatic hydrocarbons in living room of new and sick houses showed 606 ${\mu}g/m^3$ and 645 ${\mu}g/m^3$, respectively, These figures were about 40 times higher than the values 14 ${\mu}g/m^3$ in normal houses. Among the chlorinated hydrocarbons trichloroethylene in the new and sick houses were at least 50-100 times higher than the mean concentrations in normal houses. But no significant differences could be shown for the concentration of VOCs in indoor air between new houses and sick houses (p<0.05).