• Earthquakes and Structures
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• 제18권3호
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• pp.285-296
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• 2020

Dams are important structures for management of water supply for irrigation or drinking, flood control, and electricity generation. In seismic regions, the structural safety of concrete gravity dams is important due to the high potential of life and economic loss if they fail. Therefore, the seismic analysis of existing dams in seismically active regions is crucial for predicting responses of dams to ground motions. In this paper, earthquake response of concrete gravity dams is investigated using the finite element (FE) method. The FE model accounts for dam-water-foundation rock interaction by considering compressible water, flexible foundation effects, and absorptive reservoir bottom materials. Several uncertainties regarding structural attributes of the dam and external actions are considered to obtain the fragility curves of the dam-water-foundation rock system. The structural uncertainties are sampled using the Latin Hypercube Sampling method. The Pine Flat Dam in the Central Valley of Fresno County, California, is selected to demonstrate the methodology for several limit states. The fragility curves for base sliding, and excessive deformation limit states are obtained by performing non-linear time history analyses. Tensile cracking including the complex state of stress that occurs in dams was also considered. Normal, Log-Normal and Weibull distribution types are considered as possible fits for fragility curves. It was found that the effect of the minimum principal stress on tensile strength is insignificant. It is also found that the probability of failure of tensile cracking is higher than that for base sliding of the dam. Furthermore, the loss of reservoir control is unlikely for a moderate earthquake.

• Wind and Structures
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• 제16권3호
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• pp.279-300
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• 2013

This paper presents a new analysis framework for predicting the internal buffeting forces in bridge components under skew wind. A linear regressive model between the internal buffeting force and deformation under normal wind is derived based on mathematical statistical theory. Applying this regression model under normal wind and the time history of buffeting displacement under skew wind with different yaw angles in wind tunnel tests, internal buffeting forces in bridge components can be obtained directly, without using the complex theory of buffeting analysis under skew wind. A self-anchored suspension bridge with a main span of 260 m and a steel arch bridge with a main span of 450 m are selected as case studies to illustrate the application of this linear regressive framework. The results show that the regressive model between internal buffeting force and displacement may be of high significance and can also be applied in the skew wind case with proper regressands, and the most unfavorable internal buffeting forces often occur under yaw wind.

• Tribology and Lubricants
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• 제25권4호
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• pp.217-224
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• 2009

In this study, friction tests were carried out in order to investigate the friction behavior of textured surface in unlubricated state using ball-on-disk type apparatus. Test specimens were SUJ2 bearing steel ball and SM45C steel disk. Square arrays of circular micro-dimples were created on the surface of disk specimen by Nd:YAG Laser. Friction tests were performed for the disk specimen with various micro-dimple parameters and was also conducted for the variation of normal loads and relative velocities. The results showed that fiction coefficient of textured surface was lower than that of non-textured surface and the deeper depth of micro-dimple was, the lower friction coefficient obtained at the same diameter of micro-dimple in unlubricated state. Area density of micro-dimple had an effect on the friction coefficient. It was also found that friction coefficient generally decreased with the increase of normal load and relative velocity.

• Clinical and Experimental Reproductive Medicine
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• 제3권1호
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• pp.13-19
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• 1976

Serum levels of human placental lactogen have been measured by hemagglutination-inhibition reaction in 67 normal pregnant state and in 15 postpartum 24 hour state, HAIR is less sensitive and reliable method than radioimmunoassay, but simple, rapid, less expensive and fairly accurate, so it is more helpful in screening of large antenatal population with or without high risk complications. 1) Sensitivity of HPL-HAIR test kit was $0.1{\mu}g$/ml of H.P.L. serum level and had no cross reaction to HCG or male serum or non-pregenant female or newborn infant, 2) H.P.L. value was around $2{\mu}g$/ml until 24th week of pregnancy and rose to $6{\sim}8$ ${\mu}g$/ml continuously until about 36th week of pregnancy and then slightly decreased or stationary. 3) H.P.L. value in postpartum 24 hour state was undetectable. 4) There was poor correlation between maternal serum H.P.L. value at term and baby weight.

• Child Health Nursing Research
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• 제7권3호
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• pp.298-307
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• 2001

This study assessed behavioral characteristics of 73 normal neonates in Daegu area using the NBAS. Being one of few studies on this topic, the study is to document and to accumulate data on the neonatal behaviors of Korean babies. Overall scores were at moderate levels in 6 behavioral clusters including Habituation, Social Interactive, Motor System, State Organization, and State Regulation. Autonomic Stability showed relative stableness. Scores of Orientation were higher in neonates of working mothers and rural mothers. Neonates of mothers with no abortion history have higher scores in Motor System and State Organization. Score of State Organization was higher in neonates of mothers with no habitual use of amenity during their pregnancy. Scores of Habituation and State Organization, as well as scores of Motor System with State Organization, State Regulation and Autonomic Stability were positively correlated. Scores of Habituation and State Organization indicate that babies are agreeable and even tameable that is advantageous for attachment to caregiver.

• Toxicological Research
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• 제14권2호
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• pp.123-127
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• 1998

BRCA1 is a tumor suppresser gene in familial cases of breast cancer. It has been controversial whether the subcellular localization of BRCA1 is located in nuclei or cytoplasm in normal human breast cells. We found that a p220 protein was expressed in Type II Normal human breast epithelial cells (NHBEC) but not in Type I NHBEC in Western blot analysis using the 17F8 (3A2) antibody. Immunostaining using the same antibody revealed positive staining in nuclei, cytoplasm and perinuclei of Type II cells and negative staining in Type I NHBEC. The p220 protein, however, was expressed in SV40 immortalized Type I NHBEC and tumorigenic cells derived from them after x-ray and neu oncogene treatment. The subcelluar localization was mostly cytoplasmic and punctate in the nuclei. The breast carcinoma cell lines, MCF-7 and T47D, also expressed the p220 protein. Using RT-PCR, we observed the expression of BRCA1 mRNA in both Type I and Type II NHBEC. This result indicated that there might be mechanisms involved in post-translational or translational regulation of BRCA1 gene. It is speculated that the absence of BRCA1 protein expression in Type I NHBEC might playa role in their susceptibility to neoplastic transformation.

• Communications for Statistical Applications and Methods
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• 제21권5호
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• pp.461-469
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• 2014

Characteristic functions play an important role in probability and statistics; however, a rigorous derivation of these functions requires contour integration, which is unfamiliar to most statistics students. Without resorting to contour integration, Datta and Ghosh (2007) derived the characteristic functions of normal, Cauchy, and double exponential distributions. Here, we derive the characteristic functions of t, truncated normal, skew-normal, and skew-t distributions. The characteristic functions of normal, cauchy distributions are obtained as a byproduct. The derivations are straightforward and can be presented in statistics masters theory classes.

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2000년도 High Temperature Superconductivity Vol.X
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• pp.85-85
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• 2000

The normal state of high-Tc superconducting materials has been believed to contain important clues to finding the correct mechanism of the high-Tc superconductivity. One example is the existence of pseudogap in the normal state even above Tc, as observed in various measurements such as photoemission spectroscopy and tunneling conductance. In this pseudogap regime the existence of preformed pairs only with local phase coherence has been debated. Recently Choi, Bang, and Campbell[1] have proposed the occurrence of the zero-bias conductance enhancement due to Andreev quasiparticle reflection from the preformed pairs even with the local phase coherence. In this study we examine the zero-bias enhancement of the differential conductance near or slightly above Tc, using c-axis tunneling in mesa structure of Bi2Sr20a0u208+d single crystals. In slightly overdoped samples zero-bias conductance enhancement (ZBCE) has been observed over a range of 2 K above Tc. In contrast, in underdoped samples with Tc${\sim}$72K the ZBCE appears over a range of 5-6 K above Tc, a much wider temperature range than in overdoped samples. This result may pose as positive signs of the existence of prefurmed pairs in the normal state of high- Tc superconducting materials.

• Molecules and Cells
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• 제37권8호
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• pp.592-597
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• 2014

The cell membrane provides critical cellular functions that rely on its elaborate structure and organization. The structure of turtle membranes is an important part of an ongoing study of erythrocyte membranes. Using a combination of atomic force microscopy and single-molecule force spectroscopy, we characterized the turtle erythrocyte membrane structure with molecular resolution in a quasi-native state. High-resolution images both leaflets of turtle erythrocyte membranes revealed a smooth outer membrane leaflet and a protein covered inner membrane leaflet. This asymmetry was verified by single-molecule force spectroscopy, which detects numerous exposed amino groups of membrane proteins in the inner membrane leaflet but much fewer in the outer leaflet. The asymmetric membrane structure of turtle erythrocytes is consistent with the semi-mosaic model of human, chicken and fish erythrocyte membrane structure, making the semi-mosaic model more widely applicable. From the perspective of biological evolution, this result may support the universality of the semi-mosaic model.

• 자동차안전학회지
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• 제13권4호
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• pp.14-19
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• 2021

This paper presents LiDAR static obstacle map based vehicle dynamic state estimation algorithm for urban autonomous driving. In an autonomous driving, state estimation of host vehicle is important for accurate prediction of ego motion and perceived object. Therefore, in a situation in which noise exists in the control input of the vehicle, state estimation using sensor such as LiDAR and vision is required. However, it is difficult to obtain a measurement for the vehicle state because the recognition sensor of autonomous vehicle perceives including a dynamic object. The proposed algorithm consists of two parts. First, a Bayesian rule-based static obstacle map is constructed using continuous LiDAR point cloud input. Second, vehicle odometry during the time interval is calculated by matching the static obstacle map using Normal Distribution Transformation (NDT) method. And the velocity and yaw rate of vehicle are estimated based on the Extended Kalman Filter (EKF) using vehicle odometry as measurement. The proposed algorithm is implemented in the Linux Robot Operating System (ROS) environment, and is verified with data obtained from actual driving on urban roads. The test results show a more robust and accurate dynamic state estimation result when there is a bias in the chassis IMU sensor.