• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1994.10a
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• pp.21-28
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• 1994

The forced vibration with the symmetric boundary condition in nonlinear structure is studied by utilizing the characteristic of the free vibration which have two modes with the similar natural frequency. Two linear modes exist to have no concern with the amplitude. It is found that the normal mode or elliptic orbit as the newly coupled modes is generated in accordance with changing the stability. It is also known that responses for forced vibration having the small external force and damping are near mode of free vibration and the stability for each response is determined according to the stability for each response is determined according to the stability in mode of free vibration. Finally the stability and bifurcation are analyzed in proportion to increment of external force and damping.

• Journal of Biosystems Engineering
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• v.24 no.3
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• pp.253-258
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• 1999

This study was conducted to develop an automatic egg inspection system for detecting creaked eggs based on acoustic impulse response. This system includes a sound generator, a sound sensor with signal conditioner, and a computer. The sound generator that hit the sharp of the dull edges of an egg was constructed with a ceramic ball pendulum attached to a rotary type solenoid. The signal conditioner included a pre-amplifier and a digital signal processing (DSP) board. The parameters for distinguishing cracked and normal eggs were the area, the geometric centroid and the resonance frequency of power spectrum of the acoustic signal generated. An algorithm for on-line detection of the continuous transferring eggs was developed. The performance tests resulted with 91% success rate to separate cracked and normal eggs at the rate of 1 second per an egg.

• Interaction and multiscale mechanics
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• v.3 no.4
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• pp.373-387
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• 2010

This study is intended to assess low frequency sound radiated from a viaduct under normal traffic. The bridge comprises steel box girders and wide cantilever decks on which vehicles pass. The low frequency sound and the acceleration response of the bridge under normal traffic are measured to investigate how bridge vibrations affect the low frequency sound observed near the bridge. Observations demonstrate that strong relationships exist between frequency characteristic of bridge's acceleration response and the sound pressure level of low frequency sound. A noteworthy point is that the dynamic feature of the sound pressure level is mostly affected by dynamic feature of the span locating near the observation point.

• Journal of Mechanical Science and Technology
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• v.17 no.5
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• pp.698-707
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• 2003

A new quadratic response surface modeling method is presented. In this method, the incomplete small composite design (ISCD) is newly proposed to .educe the number of experimental runs than that of the SCD. Unlike the SCD, the proposed ISCD always gives a unique design assessed on the number of factors, although it may induce the rank-deficiency in the normal equation. Thus, the singular value decomposition (SVD) is employed to solve the normal equation. Then, the duality theory is used to newly develop the conservative least squares fitting (CONFIT) method. This can directly control the ever- or the under-estimation behavior of the approximate functions. Finally, the performance of CONFIT is numerically shown by comparing its'conservativeness with that of conventional fitting method. Also, optimizing one practical design problem numerically shows the effectiveness of the sequential approximate optimization (SAO) combined with the proposed ISCD and CONFIT.

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.2
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• pp.141-146
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• 2010

This paper describes the static and dynamic characteristics of body mount system which are to be considered in the early design stage. At every location of body mount the static load and dynamic response to road input were calculated using the half car model. Normal mode analysis for the half car model was also performed. In the analysis the design parameters such as the stiffness of mount rubbers and their distribution on mount location were examined for improving ride comfort especially in the lower frequency range.

• Journal of the Korean Statistical Society
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• v.30 no.4
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• pp.613-635
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• 2001

This paper proposes a skewed multivariate probit model for analyzing a correlated binary response data with covariates. The proposed model is formulated by introducing an asymmetric link based upon a skewed multivariate normal distribution. The model connected to the asymmetric multivariate link, allows for flexible modeling of the correlation structure among binary responses and straightforward interpretation of the parameters. However, complex likelihood function of the model prevents us from fitting and analyzing the model analytically. Simulation-based Bayesian inference methodologies are provided to overcome the problem. We examine the suggested methods through two data sets in order to demonstrate their performances.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.05a
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• pp.948-954
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• 2002

The structural vibration of a diesel generator set was investigated through analyses and tests. FE modeling and normal mode analysis were performed and compared with measured results for both structure components and generator set assembly. The results of component analyses were fairly well coincident with measured results but those of assembled generator set showed more or less discrepancies. Discussions were given about the uncertainties for vibration characteristics of component structures and assembled running structures especially concerning their nonlinearities and damping effects. Detailed excitation analysis fellowed by forced response analysis was done from the engine and pressure data to compare with the actual measured vibration. As results the vibration prediction for frame structures of reciprocating internal combustion engine was confirmed reliable to some extent.

• Animal Systematics, Evolution and Diversity
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• v.14 no.2
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• pp.159-164
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• 1998

The spider, Tetragnatha squamata and its prey Empoasca vitis, the tea leafhopper, were investigated in laboratory on the prey-predator relationship. The predator spider showed a significant response to the increase of the prey. The predation effiency and the response of predator to its density were examined as well. The result of the experiments are give as questions.

• Communications for Statistical Applications and Methods
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• v.29 no.3
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• pp.333-351
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• 2022

The skew-t distribution is an attractive family of asymmetrical heavy-tailed densities that includes the normal, skew-normal and Student's-t distributions as special cases. In this work, we propose an EM-type algorithm for computing the maximum likelihood estimates for skew-t linear regression models with censored response. In contrast with previous proposals, this algorithm uses analytical expressions at the E-step, as opposed to Monte Carlo simulations. These expressions rely on formulas for the mean and variance of a truncated skew-t distribution, and can be computed using the R library MomTrunc. The standard errors, the prediction of unobserved values of the response and the log-likelihood function are obtained as a by-product. The proposed methodology is illustrated through the analyses of simulated and a real data application on Letter-Name Fluency test in Peruvian students.

• Journal of the Korean Magnetic Resonance Society
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• v.21 no.1
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• pp.31-43
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• 2017

Together with radiotherapy, chemotherapy using cytotoxic agents is one of the most common therapies in cancer. Metabolic changes in cancer cells are drawing much attention recently, but the metabolic alterations by anticancer agents have not been much studied. Here, we investigated the effects of commonly used cytotoxic agents on lung normal cell MRC5 and lung cancer cell A549. We employed cis-plastin, doxorubicin, and 5-Fluorouracil and compared their effects on the viability and metabolism of the normal and cancer cell lines. We first established the concentration of the cytotoxic reagents that give differences in the viabilities of normal and cancer cell lines. In those conditions, the viability of A549 decreased significantly, whereas that of MRC5 remained unchanged. To study the metabolic alterations implicated in the viability differences, we obtained the metabolic profiles using $^1H$-NMR spectrometry. The $^1H$-NMR data showed that the metabolic changes of A549 cells are more remarkable than that of MRC5 cells and the effect of 5-FU on the A549 cells is the most distinct compared to other treatments. Heat map analysis showed that metabolic alterations under treatment of cytotoxic agents are totally different between normal and cancer cells. Multivariate analysis and weighted correlation network analysis (WGCNA) revealed a distinctive metabolite signature and hub metabolites. Two different analysis tools revealed that the changes of cell metabolism in response to cytotoxic agents were highly correlated with the Warburg effect and Reductive lipogenesis, two pathways having important effects on the cell survival. Taken together, our study addressed the correlation between the viability and metabolic profiles of MRC5 and A549 cells upon the treatment of cytotoxic anticancer agents.