• Title/Summary/Keyword: Normal response

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Evaluation of Growth, Carcass, Immune Response and Stress Parameters in Naked Neck Chicken and Their Normal Siblings under Tropical Winter and Summer Temperatures

  • Rajkumar, U.;Reddy, M.R.;Rao, S.V. Rama;Radhika, K.;Shanmugam, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.4
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    • pp.509-516
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    • 2011
  • The performance of naked neck and normal chicken was evaluated with respect to growth, carcass, immune, biochemical and stress parameters under winter and summer seasons to assess the suitability of naked neck birds under high temperatures in the global scenario of climate change. The growth performance was significantly ($p{\leq}0.05$) higher in naked neck chicken in the summer season. The dressing percentage was significantly ($p{\leq}0.05$) higher in naked neck birds in both winter and summer season because of reduced plumage. The thigh, giblet and feather proportion significantly ($p{\leq}0.05$) varied between naked neck and normal chickens in summer season. The humeral immune response to sheep red blood cells (SRBC), Newcastle disease vaccine (NDV) and cutaneous basophil hypersensitivity (CBH) did not show any significant differences among the chicken groups. The protein and cholesterol concentration observed was within the normal ranges. The total cholesterol levels in plasma were significantly ($p{\leq}0.05$) lower in naked neck birds in both the seasons. H:L ratio was significantly ($p{\leq}0.05$) lower in summer season indicating less stress in naked neck chicken. Basophil and eosinophil concentration was significantly ($p{\leq}0.05$) higher in normal chicken in summer. The lipid peroxidation was higher in full feathered birds under summer stress. The enzyme glutathione reductase (GR) levels were significantly higher during the summer and varied significantly ($p{\leq}0.05$) between the normal and naked neck chicken in both seasons. The results indicated that the naked neck birds performed significantly better at high ambient temperatures with respect to growth, carcass and biochemical parameters. It was concluded that the ability of the naked neck chicken to adapt to high temperatures foresees a viable option for the biological mitigation of climate change.

Psychophysiologic Response in Patients with Panic Disorder (공황장애환자의 정신생리적 반응)

  • Chung, Sang-Keun;Cho, Kwang-Hyun;Jung, Ae-Ja;Park, Tae-Won;Hwang, Ik-Keun
    • Sleep Medicine and Psychophysiology
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    • v.8 no.1
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    • pp.52-58
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    • 2001
  • Objectives: An Increased level of psychophysiologic arousal and diminished physiologic flexibility would be observed in patients with panic disorder compared with a normal control group. We investigated the differences of psychophysiologic response between patients with panic disorder and normal control to examine this hypothesis. Methods: Ten Korean patients with panic disorder who met the diagnostic criteria of DSM-IV were compared with 10 normal healthy subjects. In psychological assessment, levels of anxiety and depression were evaluated by State-Trait Anxiety Inventory, Beck's Depression Inventory and Hamilton Rating Scale For Anxiety and Depression. Heart rate, respiration rate, electrodermal response, and electromyographic activity were measured by biofeedback system (J & J I-330 model) to determine psychophysiologic responses on autonomic nervous system. Stressful tasks included mental arithmetic, video game, hyperventilation, and talking about a stressful event. Psychophysiologic responses were measured according to the following procedures : baseline(3 min)-mental arithmetic (3 min)-rest (3 min)-video game (3 min)-rest (3 min)-hyperventilation (3 min)-rest (3 min)-talking about a stressful event (3 min). Results: The baseline level of anxiety and depression, electrodermal response (p=.017), electromyographic activity (p=.047) and heart rate (p=.049) of patients with panic disorder were significantly higher than those of the normal subject group. In electrodermal response, patient group had significantly higher startle response than the control group during hyperventilation (p=.001). Startle and recovery responses of heart rate in the patient group were significantly lower than responses in the control group during mental arithmetic (p=.007, p=.002). In electrodermal response of the patient group, startle response was significantly higher than recovery response during mental arithmetic (p=.000) and video game task (p=.021). Recovery response was significantly higher than startle response in respiratory response during hyperventilation. Conclusion: The results showed that patients with panic disorder had higher autonomic arousal than the control group, but the physiologic flexibility was variable. We suggest that it is helpful for treatment of panic disorder to decrease the level of autonomic arousal and to recover the physiologic flexibility in certain stressful event.

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Comparison on Accommodative Response Changes in the Normal Group and Convergence Insufficiency (정상군과 폭주부족군에서 조절반응 변화량의 비교)

  • Kwak, Ho-Weon;Lee, Se-Hee;Kwak, Hyung-Bin
    • Journal of Korean Ophthalmic Optics Society
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    • v.19 no.1
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    • pp.79-85
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    • 2014
  • Purpose: This study investigated accommodative changes by measuring accommodative response, appearing on the normal and convergence insufficiency Group, by using both eyes open-view auto-refractometer (Nvision-K5001, shin-nippon, Japan). Methods: It carried out objective and subjective refractions, targeting 74 college students (54 males and 20 females) aged between 19 and 29 ($21.59{\pm}2.53$), spherical equivalent OD $-2.28{\pm}2.03$ D, OS $-2.18{\pm}2.01$ D, by measuring accommodative responses at full correction and under correction with plus lens +0.25, +0.50, +0.75 arbitrarily added. Results: In the group of normal and convergence insufficiency, the shorter fixation distances were, the greater accommodative lags showed. The group of convergence insufficiency showed the lesser changes of accommodative response than those of normal. But we found that the convergence insufficiency group had a little larger accommodative amplitude in the total fixation distances. The full correction of convergence insufficiency group and the under correction (+0.50 D) of normal were alike in the accommodative responses. We have also investigated that the correlation between accommodative responses and fixation distances was decreased steeply at the excessive low vision correction. Conclusions: Under correction (+0.50 D) in a near distance is expected to avoid unnecessary accommodative responses, make eyes relaxed and comfortable.

On the nonlinear structural analysis of wind turbine blades using reduced degree-of-freedom models

  • Holm-Jorgensen, K.;Staerdahl, J.W.;Nielsen, S.R.K.
    • Structural Engineering and Mechanics
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    • v.28 no.1
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    • pp.107-127
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    • 2008
  • Wind turbine blades are increasing in magnitude without a proportional increase of stiffness for which reason geometrical and inertial nonlinearities become increasingly important. Often these effects are analysed using a nonlinear truncated expansion in undamped fixed base mode shapes of a blade, modelling geometrical and inertial nonlinear couplings in the fundamental flap and edge direction. The purpose of this article is to examine the applicability of such a reduced-degree-of-freedom model in predicting the nonlinear response and stability of a blade by comparison to a full model based on a nonlinear co-rotating FE formulation. By use of the reduced-degree-of-freedom model it is shown that under strong resonance excitation of the fundamental flap or edge modes, significant energy is transferred to higher modes due to parametric or nonlinear coupling terms, which influence the response and stability conditions. It is demonstrated that the response predicted by such models in some cases becomes instable or chaotic. However, as a consequence of the energy flow the stability is increased and the tendency of chaotic vibrations is reduced as the number of modes are increased. The FE model representing the case of infinitely many included modes, is shown to predict stable and ordered response for all considered parameters. Further, the analysis shows that the reduced-degree-of-freedom model of relatively low order overestimates the response near resonance peaks, which is a consequence of the small number of included modes. The qualitative erratic response and stability prediction of the reduced order models take place at frequencies slightly above normal operation. However, for normal operation of the wind turbine without resonance excitation 4 modes in the reduced-degree-of-freedom model perform acceptable.

The Effects of Anti-cancer and Immune Response of Lonicerae Flos Herbal-acupuncture (금은화약침(金銀花藥鍼)의 항암 및 면역반응에 관한 실험적 연구)

  • Park, Hee-Soo;Han, Jae-Sub
    • Journal of Acupuncture Research
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    • v.23 no.4
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    • pp.205-218
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    • 2006
  • Objectives : This study was performed to investigate the effects of anti-cancer and changes In immune response of Lonicerge Flos Herbal-acupuncture. Methods Experimental studies were evaluated through the anti-cancer and immune response activities such as, cell viability, BNA fragmentation, Apoptosis, survival time, pulmonary colonization, and productivity of interleukins & $interferon-{\gamma}$. In order to study the effects of anti-cancer and changes in immune response of Lonicerae Flos Herbal-acupuncture, the groups were divided into five groups ; Normal group(non treated group), Control A group(0.2ml Normal saline for oral administration), Control B group(administration of intramuscular injection with 0.2ml Lonicerae Flos Herbal-acupuncture solution), Acupuncture group(AT, administration of acupuncture at Chungbu(L1)), and Herbal-Acupuncture group(HAT, administration of Lonicerae Flos Herbal-acupuncture at Chungbu(L1)). Results : 1. Lonicerae Flos Herbal-acupuncture(>300mg/ml) could lead cancer cell to cell death. 2. Lonicerae Flos Herbal - acupuncture (40mg/ml) caused DNA cleavage. 3. Lonicerae Flos Herbal-acupuncture(400mg/ml) caused apoptosis in the cancer cell line. 4. In mouse survival time, all of experimental groups didn't show any significant compared to the control group. 5. In pulmonary colonization assay, Lonicerae Flos Herbal-acupuncture group was less than Control A group at 7 days after induction of cancer. 6. In comparison Control A group, there was significant decrease of Interleukin-2 level in Lonicerae Flos Herbal-acupuncture group. 7. In comparison Control group, there was decrease of Interleukin-4 level in the Acupuncture group. 8. In comparison Control group, there was decrease of Interleukin-10 level in the Acupuncture group. 9. In comparison Control group, there was significant increase of Interleukin-12 level in Acupuncture group and Lonicerae Flos Herbal-acupuncture group. 10. In comparison Control group, there was significant increase of $Interferon-{\gamma}$ level in Acupuncture group. Conclusion : According to above mentioned results, Lonicerae Flos Herbal- acupuncture is expected to be effective for anticancer and improvement in immune response.

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Nonproportional viscous damping matrix identification using frequency response functions (주파수 응답 데이터를 이용한 비비례 점성감쇠행렬 추정)

  • Min, Cheon-Hong;Kim, Hyung-Woo
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.4
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    • pp.369-373
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    • 2016
  • Accurate identification of damping matrix in structures is very important for predicting vibration responses and estimating parameters or other characteristics affected by energy dissipation. In this paper, damping matrix identification method that use normal frequency response functions, which were estimated from complex frequency response functions, is proposed. The complex frequency response functions were obtained from the experimental data of the structure. The nonproportional damping matrix was identified through the proposed method. Two numerical examples (lumped-mass model and cantilever beam model) were considered to verify the performance of the proposed method. As a result, the damping matrix of the nonproportional system was accurately identified.

A Study on the Eating Habits of Obese Elementary School Students in a Rural Community (농촌 지역 고학년 비만 초등학생의 식습관에 관한 연구)

  • Lee, Da-Hong
    • Journal of the East Asian Society of Dietary Life
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    • v.17 no.5
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    • pp.626-633
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    • 2007
  • This study was conducted to determine the eating habits of obese elementary school students residing in Iksan city, in June 2006 using 1167 participants(obese: 233, normal weight: 934). The results are summarized as follows. The average age was 12 years-old in both the obese and normal weight groups. The average BMI, ideal body weight and obesity index in the obese and normal weight groups were $24.8kg/m^2$, 39.8 kg, and 32.5% and $18.2kg/m^2$, 37.7 kg and -1.4%, respectively. Regarding the number of subject who acknowledged their physical build, the obese group was highest(88.9%) in stating obese or extremely obese, while the normal group was highest(71.5%) in stating they were normal weight. For the frequency of eating breakfast, the obese group the results were: "eating it everyday"(69.1%) and $"3{\sim}4\;times/week"$ (13.7%), while in the normal weight group, the highest response was "eating it everyday"(75%) and the lowest response was "never eat it"(4.1%). In terms of having breakfast with someone, there were slight differences for eating alone between the obese group(17.4%) and normal group(12.4%) and also between the obese group(19.6%) and normal group (39.6%) for eating with parents. There were considerable gaps in the association of eating habits with weight such as having irregular meals in the obese group(52.4%) and having regular meals in the normal group(61.1%). The frequency of having snacks was different by the rate of obesity, where 65.9% of the obese group, and 57.8% of the normal group had snacks more than once. There were significant differences in the practice of controlling intake with the obese group at 77.3% and the normal group at 36.3%. There were high numbers regarding eating more than average in stressful times for both the obese group(10.3%) and normal group(7.7%). The results of this study show the prevalence of obesity in Iksan, and proper nutrition education is currently needed. Moreover, the greater the level of obesity, the higher the frequency of skipping breakfast, eating alone, and eating irregular meals, and the more experience in attempting to control weight. To resolve the problems triggered by inappropriate food habits, proper food and eating methods to control weight should be included in nutrition education programs for elementary students.

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Effect Inosiplex on Cellular and Humoral Immune Response (Inosiplex가 세포성(細胞性) 및 체액성면역반응(體液性免疫反應)에 미치는 영향(影響))

  • Ha, Tai-You;Lee, Hern-Ku
    • The Journal of the Korean Society for Microbiology
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    • v.16 no.1
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    • pp.57-64
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    • 1981
  • The clinical need for agents to modify immune response in the treatment of viral infection has lead to an increased interest in cellular and biochemical mechanisms regulating the immune response and to the development of a variety of biological and chemical substance with immunomodulatory activity. Inosiplex has shown antiviral activity in tissue culture, animal models and huamn studies through augmentation of immune response. However, the effect of inosiplex on immune response in animal has not been extensively analyzed, and the effect of inosiplex on immune response has been paradoxical depending on the time of administration of inosiplex in relation to that of antigen. Therefore, this study was undertaken to assess the effect of inosiplex on the immune response to sheep red blood cells(SRBC) in normal and viral infected mice. Inosiplex increased cellular immune response and plaque forming lymphocyte response to SRBC, decreased the recovery of S. typhimurium from infected mice spleen, and restored the depressed cellular immune response by measle and newcastle disease virus infections. All of the above results were observed only when inosiplex was given after immunization but did not when given before immunization. These results indicate that inosiplex stimulate the efferent are of immune response and may even block the afferent are, and suggest that inosiplex is a very promising drug in therapy of many viral infections.

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Transient Response of a Permeable Crack Normal to a Piezoelectric-elastic Interface: Anti-plane Problem

  • Kwon, Soon-Man;Lee, Kang-Yong
    • Journal of Mechanical Science and Technology
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    • v.18 no.9
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    • pp.1500-1511
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    • 2004
  • In this paper, the anti-plane transient response of a central crack normal to the interface between a piezoelectric ceramics and two same elastic materials is considered. The assumed crack surfaces are permeable. By virtue of integral transform methods, the electro elastic mixed boundary problems are formulated as two set of dual integral equations, which, in turn, are reduced to a Fredholm integral equation of the second kind in the Laplace transform domain. Time domain solutions are obtained by inverting Laplace domain solutions using a numerical scheme. Numerical values on the quasi-static stress intensity factor and the dynamic energy release rate are presented to show the dependences upon the geometry, material combination, electromechanical coupling coefficient and electric field.

GLOBAL STABILITY OF THE VIRAL DYNAMICS WITH CROWLEY-MARTIN FUNCTIONAL RESPONSE

  • Zhou, Xueyong;Cui, Jingan
    • Bulletin of the Korean Mathematical Society
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    • v.48 no.3
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    • pp.555-574
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    • 2011
  • It is well known that the mathematical models provide very important information for the research of human immunodeciency virus type. However, the infection rate of almost all mathematical models is linear. The linearity shows the simple interaction between the T-cells and the viral particles. In this paper, a differential equation model of HIV infection of $CD4^+$ T-cells with Crowley-Martin function response is studied. We prove that if the basic reproduction number $R_0$ < 1, the HIV infection is cleared from the T-cell population and the disease dies out; if $R_0$ > 1, the HIV infection persists in the host. We find that the chronic disease steady state is globally asymptotically stable if $R_0$ > 1. Numerical simulations are presented to illustrate the results.