• 제목/요약/키워드: Normal response

검색결과 2,180건 처리시간 0.033초

Heme Oxygenase Expression in Skin of Hairless Mouse Using Ultraviolet A (320-400 nm) Radiation as an Inducer

  • Munif Allanson;Reeve, Vivienne-E
    • Journal of Photoscience
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    • 제9권3호
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    • pp.33-36
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    • 2002
  • This study describes RT-PCR and in situ hybridisation protocols, and the immunohistochemical detection method that we have developed to detect and localise cells that express HO-1 in the skin. We found that HO-1 mRNA was absent in normal mouse skin, but after UVA irradiation HO-1 mRNA was expressed in the dermal fibroblasts, and strongly in basal epidermal cells. HO-1 protein was also induced strongly in dermal fibroblasts, and also in epidermal cells. In addition, the HO substrate heme was reduced in skin microsome at 72 hrs post UVA (when HO activity is high). At the same time, the HO products bilirubin and iron levels were elevated in the cutaneous tissue. Thus in addition to a dermal response, there appears to be an epidermal HO response to UVA in vivo that may be relevant for immune modulation by UVA radiation.

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부하차단 메카니즘에 관한 연구 (A Study on Mechanism of Load Shedding)

  • 신호성;문종필;김재철;송경빈
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 하계학술대회 논문집 A
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    • pp.162-164
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    • 2004
  • Electrical power peak demand of Republic of Korea is annually growing and the peak demand has occurred in the summer. It is difficult that we handle with constructing power plants and increasing generation capacity to cope with a suddenly increased demand due to the cost problem, difficulty to find the new plant site, and the spread of the NIMBY. The alternative of the above problem is to efficiently manage demand of electrical power. Accordingly, load shedding of a section of demand side management is investigated. First we surveyed a trend of research in the domestic and overseas, for load curtailment and demand response program. After reviewing several demand response programs, the future research direction for load shedding in emergency and normal operation is introduced.

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소프트웨어 업데이트 유형별 위협요소 및 대응방안 (Threats and response measures according to the type of software updates)

  • 이대성
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2014년도 춘계학술대회
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    • pp.277-279
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    • 2014
  • 지능형 타깃 지속 공격에 업데이트 서버가 유포수단으로 사용되고, 업데이트 프로그램은 악성코드의 실행 또는 안티바이러스 시그니처와 같은 애플리케이션 데이터의 조작에도 취약하기 때문에 SW 업데이트 위협요소의 식별 및 방지대책이 시급하다. 본 논문에서는 국내외 SW의 업데이트 구조와 업데이트 과정의 취약성 공격 및 대응방안을 살펴보고, 국내 유명 SW의 업데이트 로그를 추출/분석하여 화이트리스트를 식별하는데 필요한 정상적인 프로그램의 업데이트 구성요소를 도출한다.

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Ultimate strength of stiffened panels subjected to non-uniform thrust

  • Anyfantis, Konstantinos N.
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제12권1호
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    • pp.325-342
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    • 2020
  • The current study is focused on the evaluation of the ultimate strength of stiffened panels found in ship hull structures that are subjected to combined uniaxial thrust, in-plane and out-of-plane bending moments. This loading condition, which is in general ignored when performing buckling checks, applies to representative control geometries (stiffener with attached plating) as a consequence of the linearly varying normal stresses along the ship's depth induced by the hull-girder vertical bending moment. The problem is generalized by introducing a non-uniform thrust described by a displacement ratio and rotation angle and by introducing the slenderness ratios, within the practical range of interest. The formed design space is explored through methods sourcing from Design of Experiments and by applying non-linear finite element procedures. Surrogate empirical models have been constructed through regression analysis and Response Surface Methods. An additional empirical model is provided to the literature for predicting the ultimate strength under uniaxial thrust. The numerical experimentation has shown that is a significant influence on the ultimate strength of stiffened panels as the thrust non-uniformity increases.

Impact of geometrical parameters on SGEMP responses in cylinder model

  • Chen, Jian-Nan;Zhang, Jun-Jie
    • Nuclear Engineering and Technology
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    • 제54권9호
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    • pp.3415-3421
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    • 2022
  • This paper is aimed to find out the impact of the geometrical parameters, mainly the radius and the height of a cylinder, on the SGEMP response including the famous scaling law in the classical cylinder model using a homemade PIC code UNIPIC-3D. We computed the electric fields at the center and at the edge on the emission head face with different radii and heights under normal X-rays incidence. The results show that the electric field will increase with the radius but decrease with the height. We analyze the scaling law that links the electric field product and fluence product, and whereafter an irreconcilable contradiction raises when the radius is changeable, which limits the application range of the scaling law. Moreover, the field-height-radius relation is found and described by a combination of logarithmic and minus one-quarter numerical fitting law firstly. Particle and magnetic field distributions are used to explain all the behaviors of the fields reasonably. All the findings will assist the evaluation of SGEMP response in spacecraft protection.

Open-Loop Responses of Droplet Vaporization to Linear Normal Acoustic Modes

  • Kim, S.Y.;W.S. Yoon
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2004년도 제22회 춘계학술대회논문집
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    • pp.155-164
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    • 2004
  • In order for studying pressure-coupled dynamic responses of droplet vaporization, open-loop experiment of an isolated droplet vaporization exposed to pressure perturbations in stagnant gaseous environment is numerically conducted, Governing equations are solved for flow parameters at gas and liquid phases separately and thermodynamic parameters at the interfacial boundary are matched for problem closure. For high-pressure effects, vapor-liquid interfacial thermodynamics is rigorously treated. A series of parametric calculations in terms of mean pressure level and wave frequencies are carried out employing a n-pentane droplet in stagnant gaseous nitrogen. Results show that wave instability in view of pressure-coupled vaporization response seems more susceptible at higher pressures and higher wave frequencies. Mass evaporation rate responding to pressure waves is amplified with increase in pressure due to substantial reduction in latent heat of vaporization. Augmentation of perturbation frequency also enhances amplification due to the reduction of phase differences between pressure perturbation and surface temperature fluctuation.

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비상 디젤발전기용 배전반의 내진안전성에 관한 연구 (A Study on the Seismic Stability of an Existing Switchboard for Emergency Diesel Generator)

  • 하능교;김재실
    • 한국산업융합학회 논문집
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    • 제26권6_3호
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    • pp.1341-1347
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    • 2023
  • This study proposes to ensure the seismic stability of an existing switchboard for emergency diesel generator by applying mode analysis, static analysis and dynamic analysis. First, a three dimensional model for the swithboard was made with simplification for mode analysis. Next, The mode analysis for the finite element model of the existing switchboard was performed. The 1st natural frequency below 33 Hz, the seismic safety cutoff frequency, was calculated to be 21.943 Hz. Finally, based on the seismic stability theory, the von-Mises equivalent stresses derived by structural analysis and response spectrum analysis under the normal and faulted conditions were 74.179 MPa and 49.769 MPa, respectively. These are less than specified allowable stresses. So seismic stability was confirmed.

Different Phosphate Transport in the Duodenum and Jejunum of Chicken Response to Dietary Phosphate Adaptation

  • Fang, Rejun;Xiang, Zhifeng;Cao, Manhu;He, Jia
    • Asian-Australasian Journal of Animal Sciences
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    • 제25권10호
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    • pp.1457-1465
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    • 2012
  • Intestinal phosphate (Pi) absorption across the apical membrane of small intestinal epithelial cells is mainly mediated by the type IIb Na-coupled phosphate co-transporter (NaPi-IIb), but its expression and regulation in the chicken remain unclear. In the present study, we investigated the mRNA and protein levels of NaPi-IIb in three regions of chicken small intestine, and related their expression levels to the rate of net phosphate absorption. Our results showed that maximal phosphate absorption occurs in the jejunum, however the highest expression levels of NaPi-IIb mRNA and protein occurs in the duodenum. In response to a low-Pi diet (TP 0.2%), there is an adaptive response restricted to the duodenum, with increased brush border membrane (BBM) Na-Pi transport activity and NaPi-IIb protein and mRNA abundance. However, when switched from a low-(TP 0.2%) to a normal diet (TP 0.6%) for 4 h, there is an increase in BBM NaPi-IIb protein abundance in the jejunum, but no changes in BBM NaPi-IIb mRNA. Therefore, our study indicates that Na-Pi transport activity and NaPi-IIb protein expression are differentially regulated in the duodenum vs the jejunum in the chicken.

DSP 오디오 프로세서를 이용한 스피커 주파수 특성 개선에 관한 연구 (The Research On the improvements of Speaker's Frequency Characteristic using DSP Audio Processor)

  • 이순려;최홍섭
    • 디지털콘텐츠학회 논문지
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    • 제8권3호
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    • pp.341-346
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    • 2007
  • 스피커는 전기적 입력 신호를 소리로 전달해 준다. 이 과정에서 특정 주파수에서 변형이 발생하게 되고 그 결과 소리도 변하게 된다. 본 논문은 스피커 출력이 오디오 대역에서 변형이 발생한 경우 이 주파수 대역을 보정하는 방법으로 DSP AMP를 스피커 유닛과 결합시킨 VADSM(Value-Added Digital Speaker Module)를 제안한다. VADSM은 EQ 조정 기능을 이용하여 소리의 변형이 발생한 주파수 대역의 이득을 조정함으로써 스피커 출력의 평탄한 응답 특성을 유지하도록 한다. VADSM은 DSP AMP를 스피커 유니트와 결합하여 스피커 모듈로 만들어지는데 EQ 조정값을 가지고 있어야 한다. 스피커 출력을 마이크로 입력받아서 FFT를 실행한 후 주파수 스펙트럼을 조사하여 주파수별 이득을 추출해 낸 후 VADSM의 EQ를 조정하도록 하는 시스템이다.

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Forced vibration of the elastic system consisting of the hollow cylinder and surrounding elastic medium under perfect and imperfect contact

  • Akbarov, Surkay D.;Mehdiyev, Mahir A.
    • Structural Engineering and Mechanics
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    • 제62권1호
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    • pp.113-123
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    • 2017
  • The bi-material elastic system consisting of the circular hollow cylinder and the infinite elastic medium surrounding this cylinder is considered and it is assumed that on the inner free face of the cylinder a point-located axisymmetric time harmonic force, with respect to the cylinder's axis and which is uniformly distributed in the circumferential direction, acts. The shear-spring type imperfect contact conditions on the interface between the constituents are satisfied. The mathematical formulation of the problem is made within the scope of the exact equations of linear elastodynamics. The focus is on the frequency-response of the interface normal and shear stresses and the influence of the problem parameters, such as the ratio of modulus of elasticity, the ratio of the cylinder thickness to the cylinder radius, and the shear-spring type parameter which characterizes the degree of the contact imperfectness, on these responses. Corresponding numerical results are presented and discussed. In particular, it is established that the character of the influence of the contact imperfection on the frequency response of the interface stresses depends on the values of the vibration frequency of the external forces.