• Title/Summary/Keyword: Normal elderly

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Antioxidant Status and its Relationship to Plasma Cytokine Levels in Korean Elderly Women Living in Seoul

  • Kim, Mi-Joung;Kim, Jung-Hee
    • Journal of Community Nutrition
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    • v.6 no.2
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    • pp.103-109
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    • 2004
  • Body antioxidant status is an important factor for the prevention of many chronic diseases in the elderly. This study was done to investigate antioxidant status and its relationship to immune response by measuring plasma cytokine (IL-2 and IL-6) levels in elderly women. Subjects were 76 elderly women aged over 60 years, visiting Jangwhi Social Welfare Center of Seongbook-Gu in Seoul. Subjects were divided into 3 groups according to age (< 65, 65 - 74, > 75). Dietary intakes were assessed by semi-quantitative food frequency questionnaires (SFFQ). Plasma vitamin C level was measured by 2,4-dinitrophenylhydrazine method and plasma levels of vitamin E, A and ${\beta}$-carotene were measured by HPLC. Plasma levels of IL-2 and IL-6 were determined with a solid phase sandwich enzyme linked-immuno-sorbent assay (ELISA) using commercial kits. The average intakes of antioxidant vitamins were 96.3mg (137.5% of RDA) for vitamin C and 523.3 ${\mu}$gRE (74.8% of RDA) for vitamin A in elderly women. All of the average plasma levels of antioxidant vitamins were within normal range. However the percentage of the elderly women with deficiency plus marginal values were 7.9% in vitamin C, 9.2% in vitamin A and 7.9% in vitamin E. Plasma levels of IL-2 and IL-6 were 27.1${\pm}$7.1pg/ml and 5.9${\pm}$5.3pg/ml in elderly women. Correlation data showed that plasma IL-2 level was negatively correlated with plasma vitamin C level. In addition, IL-6 level was also negatively correlated with plasma vitamin C, A and E levels, respectively. There was a significant positive correlation between erythrocyte thiobarbituric acid-reactive substance(TB-ARS) level and plasma IL-2 or IL-6 levels. In addition, erythrocyte TBARS level showed a significant positive correlation with plasma total antioxidant status (TAS) level and a significant negative correlation with plasma vitamin C level. Overall results might imply that the decreased levels of antioxidant vitamins result in an increase in oxidative stress and thereby increase cytokine production such as IL-2 and IL-6. However further research is required to elucidate these relationships.

Reliability of Nutritional Screening Using DETERMINE Checklist for Elderly in Korean Rural Areas by Season (우리나라 농촌지역 노인들의 영양점검표(DETERMINE)를 통한 계절별 영양상태 판정의 신뢰도 분석 연구)

  • Moon, Hyun-Kyung;Kong, Jung-Eun
    • Korean Journal of Community Nutrition
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    • v.14 no.3
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    • pp.340-353
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    • 2009
  • It is very important to screen the elderly for nutritional risk, because nutritional status is a critical factor to maintain their health. Some nutrition checklists used in Korea for the elderly are from other countries. Reliability of those checklist in Korea is not studied enough. This survey was done for the elderly over 65-years-old who live in Hong-cheon, An-dong, Dam-yang and Yeon-gi in Korea (subject; summer: 146, winter: 145) to study the reliability of DETERMINE checklist which is adopted widely in Korea. Using the score of DETERMINE checklist, the elderly were divided as high, middle and low risk groups. For nutritional assessment for those elderly, dietary assessment using 24 recall, anthropometry, biochemical assessment and health condition were used. Results for the checklist showed that percentage below EAR for energy intake and protein intake in winter were higher in the high risk group than other groups. The intakes of phosphorus and iron and most vitamins were below the DRI. The percentage of subjects with intake below DRI was highest in the high risk group. Sensitivity, specificity, and positive predictive values using the DETERMINE were calculated using 6 point as a cut-off point. Subjects were divided into two groups by MAR (MAR < 0.75:undernutrition, MAR < 0.75 : normal). Sensitivity recorded 49.4% and 34.3%, specificity did 61.9% and 65.4 and Positive predictive value did 62.1% and 46.0% each for summer and winter. Results of screening using DETERMINE Checklist were not matched with dietary assessment but not with anthropometric and biochemical measurement. In conclusion DETERMINE 'Checklist' is shown be a good screening tool for finding out risk groups for dietary intake in the elderly, It needs to verify reliability and validity through large-scale survey.

Prediction of Depression among Elderly with Mild Cognitive Impairment Living in the Community (경도인지장애 노인의 우울 예측 요인)

  • Shin, Kyung-Rim;Kang, Youn-Hee;Kim, Mi-Young;Jung, Duk-Yoo;Lee, Eliza
    • Korean Journal of Adult Nursing
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    • v.24 no.2
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    • pp.171-182
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    • 2012
  • Purpose: This study aimed to identify depression and its predictors among Korean community-dwelling elderly with mild cognitive impairment. Methods: Secondary data analyses of the data collected by the "Study on tailored integration program for reinforcing cognitive and physical function of the frail elderly. The study used data from one-to-one interviews using structured questionnaires. The subjects were 346 community-dwelling elderly who visited a healthcare center in Seoul, Korea. A descriptive correlational study design was utilized to explore depression and its predictors including physical factors and psychosocial factors among the elderly with mild cognitive impairment. Data were analyzed using t-test, Pearson's correlation, and hierarchical regression. Results: Mean score of depression was within normal limit $11.61{\pm}6.69$. Somatic symptoms, negative life events (severity), social support were shown as significant predictors of depression. The most influential predictor for depression was somatic symptoms (${\beta}$=.340, $p$ <.001). Conclusion: To prevent and relieve depression in the elderly with mild cognitive impairment, nursing intervention strategies which consider well-balanced physical and psychosocial aspects are needed. In particular, a specific nursing intervention strategy is required to improve physical health of the elderly with mild cognitive impairment.

Electroglottographic Measurements of Glottal Function in Voice according to Gender and Age

  • Ko, Do-Heung
    • Phonetics and Speech Sciences
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    • v.3 no.1
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    • pp.97-102
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    • 2011
  • Electroglottography (EGG) is a common method for providing non-invasive measurements of glottal activity. EGG has been used in vocal pathology as a clinical or research tool to measure vocal fold contact. This paper presents the results of pitch, jitter, and closed quotient (CQ) measurements in electroglottographic signals of young (mean = 22.7 years) and elderly (mean = 74.3 years) male and female subjects. The sustained corner vowels /i/, /a/, and /u/ were measured at around 70 dB SPL since the most notable among EGG variables is the phonation intensity, which showed positive correlation with closed phase. The aim of this paper was to measure EGG data according to age and gender. In CQ, there was a significant difference between young and elderly female subjects while there was no significant difference between young and elderly male subjects. The mean value for young males was higher than that for elderly males while the mean value for young females was lower than that for elderly females. Thus, it can be said that in mean values, increased CQ was related to decreased age for females, while CQ decreased for males as the speaker's age decreased. Although the laryngeal degeneration due to increased age seems to occur to a lesser extent in females, the significant increase of CQ in elderly female voices could not be explained in terms of age-related physiological changes. In standard deviation of pitch and jitter, the mean values for young and elderly males were higher than that for young and elderly females. That is, male subjects showed higher in mean values of voice variables than female subjects. This result could be considered as a sign of vocal instability in males. It was suggested that these results may provide powerful insights into the control and regulation of normal phonation and into the detection and characterization of pathology.

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Body mass index and relative handgrip strength are associated with the prevalence of hypertension in Korean elderly: Korean national fitness assessment in 2019

  • Kim, Ji Young;Park, Hun-Young;Kim, Jisu;Lim, Kiwon
    • Korean Journal of Exercise Nutrition
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    • v.25 no.2
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    • pp.26-32
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    • 2021
  • [Purpose] This study aimed to analyze the prevalence of hypertension according to the body mass index (BMI) and relative handgrip strength (RHGS) among elderly individuals in Korea. [Methods] We analyzed the data of 44,183 Korean elderly individuals over 65 years old (men: n = 15,798, age = 73.31 ± 5.04 years, women: n = 28,385, age = 72.14 ± 5.04 years) obtained from the Korean National Fitness Assessment in 2019. All the participants were categorized into three groups according to the BMI and RHGS; additionally, one-way ANOVA and logistic regression analysis were performed. [Results] Overweight (men: 1.16 odds ratio [OR] 1.06-1.26, 95% confidence interval [CI]; women: 1.15 OR, 1.07-1.23 95% CI) and obese (men: 1.54 OR, 1.42-1.66 95% CI; women: 1.44 OR, 1.36-1.53 95% CI) elderly individuals showed a higher prevalence of hypertension than elderly individuals with normal weight, after controlling for age. In men, a lower RHGS was associated with a higher prevalence of hypertension after controlling for age (weak RHGS: 1.09 OR, 1.00-1.17 95% CI; middle RHGS: 1.21 OR, 1.12-1.31 95% CI vs. strong RHGS). [Conclusion] A higher BMI was associated with the prevalence of hypertension in the elderly Korean population. In addition, a lower RHGS was associated with the prevalence of hypertension in elderly Korean men.

Function Evaulation and Related factors in The Elderly (노인의 기능 평가 및 관련요인)

  • Kang, Jeom-Deok;Kim, Jong-Bong
    • Journal of Korean Physical Therapy Science
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    • v.8 no.1
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    • pp.813-820
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    • 2001
  • Objectives: The objective of this study was to investigate function evaulation and related factors in the elderly. Methods: Korean version of ADL and IADL were measured for 40 normal in the Elderly in July 15-20. 2000. Their ages were 65 or more in years. 14 items from Modified Barthel Index and 14 items from Modified Lambeth Disability Screening Questionnaire were used. Results: The frequency of disability was the highest in Heavy homework(85.0%) folliwed by Walking on level 50 yards or moer(5.0%), Up&down stairs for 1 flight(5.0%) in 28 items from Modified Barthel Index and Modified Lambeth Disability Screening Questionnaire. Conclusions: Results indicated that no smoking and drinking at onset had high Modified Barthel Index. Modified Lambeth Disability Screening Questionnaire was associated with age.

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Assesssment and Related factors on Cognitive Function in The Elderly (노인의 인지기능 평가 및 관련요인)

  • Kang, Jeom-Deok
    • Journal of Korean Physical Therapy Science
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    • v.7 no.2
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    • pp.495-502
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    • 2000
  • Objectives: The aim of this study was to analyze the effect assesssment and related factorson cognitive function in the Elderly. Methods: Korean version of MMSE-K was tested for 40normal in the Elderly in July 15-20 2000. Their ages were 65 or more in years. Results: Age, sex, marriage and education had significant effects on the MMSE-K scores(P<.05). MMSE-K as follow definite dementia$(\geq24)$ is 47.5%, definite non-dementia$(\leq19)$ is 40.0%, and questionable dementia(20-23) is 12.5% in distributions for cognitive function, respectively. Conclusions: Results indicated that age is increased and female at onset had high cognitive functions.

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A Case of Recurrent Hyponatremia in the Elderly Improved by Samilsingi-hwan: A Case Report (노인에서 반복되는 저나트륨혈증이 삼일신기환 투여로 개선된 1례 : 증례보고)

  • Jeon, Cheon-hoo;Cho, Chung-sik
    • The Journal of Internal Korean Medicine
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    • v.40 no.6
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    • pp.1311-1317
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    • 2019
  • Objectives: This report aims to present the case of Korean medicine therapies including Samilsingi-hwan on recurrent hyponatremia in the elderly. Method: A laboratory test was conducted on a patient with general weakness, anorexia, and excess salivation. The patient was diagnosed with hyponatremia and so received intravenous fluid treatment. Results: We continued fluid treatment until electrolyte levels of sodium returned to normal, but the levels gradually dropped repeatedly when the fluid treatment was discontinued. After changing the herbal medicine to Samilsingi-hwan, recurrence of hyponatremia was not seen, even after stopping the fluid treatment. Clinical symptoms also improved during 35 days of hospitalization. Conclusion: This case demonstrates that Samilsingi-hwan may be effective in recurrent hyponatremia in the elderly. Further research is needed.

BMI, Depression, and Fluid Deficit in Hospitalized Elders (입원 노인의 체질량 지수와 우울에 따른 수분섭취 부족)

  • Shin, Dong-Soo
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.14 no.1
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    • pp.83-91
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    • 2007
  • Purpose: This study was done to examine the differences in the fluid volume deficit according to levels of depression and BMI. The results of this study will provide fundamental information for developing nursing interventions for hydration management. Method: The participants were 51 hospitalized elderly people in K province. Data were collected from September 4 to 30, in 2006. A structured questionnaire was used for the data collection. Frequencies, Percentages, Means, Standard Deviation, t-test, Mann-Whitney U test, and Kruskal-Wallis test were used with the SPSS Program to analyze the data. Results: There were significant differences in the fluid volume deficit between elders in the depressed and normal groups. Participants who had a BMI of less than $21kg/m^2$ had the highest fluid volume deficit. Conclusion: Water is an essential part of the human body although it is least studied in elderly people. Health care providers need to increase awareness of the importance of hydration status among hospitalized elderly people with chronic illnesses.

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The Change of Plasma Neurotransmitters Concentration after Aromatherapy in Dementia Patients (라벤더향 흡입 후 치매환자의 혈장 중 신경전달물질의 농도변화)

  • Lee, Kyung-Bok;Kang, Young-Sook
    • YAKHAK HOEJI
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    • v.56 no.2
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    • pp.86-91
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    • 2012
  • The objective of this study is to examine how different concentration of neurotransmitters in plasma between patients with dementia and normal people regarding the inhalation of lavender oil. This study subjects were 9 elderly patients with dementia who live in nursing home and 9 normal women. Before and after inhalation, they were collected blood sample. Norepinephrine (NE), serotonin (5-HT), dopamine (DA), and r-aminobutyric acid (GABA) concentration analysis were performed. Before inhalation, dementia patients were significantly different with the normal group in GABA and DA, NE. Following inhalation in experimental group, dementia patients and normal group were only significantly increased in 5-HT. But it did not significantly change in the other neurotransmitters. After inhalation, dementia patients were significantly different with the normal group in GABA and 5-HT. This result suggests that the increase of 5-HT release by the inhalation of lavender oil related to reduce the behavioral and psychological symptoms of dementia.