• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.1
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• pp.79-88
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• 2018

With the increasing popularity of electronic toll collection system using 5.8 GHz dedicated short-range communications (DSRC) technology, DSRC-based travel-time collection systems have been deployed on major urban and rural arterial routes in Korea. However, since probe sample sizes are frequently insufficient in probe-based systems, the gathered travel times from probe vehicles fluctuate significantly compared to those of the population; as a result, the accuracy of the collected travel times could decrease. To mitigate the fluctuations (also known as biases), smoothing techniques need to be applied. In this study, some smoothing techniques-moving average, the Loess, and Savitzky-Golay filtering-were applied to probe travel times. Resultantly, the error in the smoothed travel times at the lowest sampling plan (5%) decreased as much as 45% compared to those in non-smoothed travel times. The results of this study can be practically applied to probe-based travel-time estimation systems for providing reliable travel times along the travel corridor.

• Journal of Acupuncture Research
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• v.23 no.6
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• pp.177-187
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• 2006

Objectives : Bloodletting therapeutics is one of the most popular oriental treatments in Korea. In this study, we operate the Telephone Survey for grasping clinical actual state bloodletting therapeutics in Korea. Methods : The list of the Korean medical doctors with experiences more than 10 years is provided by the Association of the Korean Oriental Medicine. A stratified random sample of Korean medical doctors is drawn for the telephone interviews. We choose a bound on the error of estimation equal to 3.2 percentage, and the sample size is 321 for the national sample. We develop a questionnaire for telephone interviews. We carefully design the questionnaire to minimize non-sampling errors by using the focus group activities and the pretest. We give the details of the results based on the sample design. Also, we present some socialdemograhpic characteristics for the samples. Telephone interviews with them were conducted by the well-trained interviewers of College of Korean Medicine student from 11th May 2006 to 17th May 2006. Results : 1. Two hundred eighty eight(89.4%) out of 322 Korean oriental medical doctors used bloodletting therapeutics. 2. The most common main bloodletting treatment is reported by patients was musculo-skeletal disorder(60.2%). 3. Two hundred ninety one(90.3%) out of 322 Korean oriental medical doctors opposed that commercial using bloodletting without medical diagnosis. Conclusion : Bloodletting therapeutics is one of the most popular oriental treatments in Korea. The majority(89.4%) of Korean medical doctors used bloodletting therapeutics in this survey.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.11
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• pp.16-23
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• 2009

A 12b 10MS/s pipelined ADC with low DC gain amplifiers is presented. The pipelined ADC using a reference scaling technique is proposed to compensate the gain error in MDACs due to a low DC gain amplifier. To minimize the performance degradation of the ADC due to amplifier offset, the proposed offset trimming circuit is employed m the first-stage MDAC amplifier. Additional reset switches are used in all MDACs to reduce the memory effect caused by the low DC gain amplifier. The measured differential and integral non-linearities of the prototype ADC with 45dB DC gain amplifiers are less than 0.7LSB and 3.1LSB, respectively. The prototype ADC is fabricated in a $0.35{\mu}m$ CMOS process and achieves 62dB SNDR and 72dB SFDR with 2.4V supply and 10MHz sampling frequency while consuming 19mW power.

• Survey Research
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• v.12 no.3
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• pp.25-48
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• 2011

In this paper, we overview the sample design, sampling error, non-response rate and prediction errors of the exit poll conducted for 2010 local elections and discusses how to detect a prediction bias in exit poll. To investigate the bias problem in exit poll in regional(Si-Do) level, we analyze exit poll data for 2007 presidential election and 2006 local elections as well as 2010 local elections in Korea. The measure of predictive accuracy A proposed by Martin et al.(2005) is used to assess the exit poll bias. The empirical studies based on three exit polls clearly show that there exits systematic bias in exit poll and the predictive bias of candidates affiliated to conservative party (such as Hannara-Dang) is serious in the specific regions. The result of this study on systematic bias will be very useful to improving the exit poll methodology in Korea.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.41 no.5
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• pp.53-62
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• 2004

In this study, an improved post-processing technique for correcting MRI artifact due to the unknown respiratory motion in the imaging plane is presented. Respiratory motion is modeled by a two-Dimensional linear expending-shrinking movement. Assuming that the body tissues are incompressible fluid like materials, the proton density per unit volume of the imaging object is kept constant. According to the introduced model, respiratory motion imposes phase error, non-uniform sampling and amplitude modulation distortions on the acquired MRI data. When the motion parameters are known or can be estimatead a reconstruction algorithm based on biliner superposition method was used to correct the MRI artifact. In the case of motion parameters are unknown, first, the spectrum shift method is applied to find the respiratory fluctuation function, x directional expansion coefficient and x directional expansion center. Next, y directional expansion coefficient and y directional expansion center are estimated by using the minimum energy method. Finally, the validity of this proposed method is shown to be effective by using the simulated motion images.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.39 no.7
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• pp.57-65
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• 2002

In this paper, a 2.5V 10-bit 300MSPS CMOS D/A Converter is described. The architecture of the D/A Converter is based on a current steering 8+2 segmented type, which reduces non-linearity error and other secondary effects. In order to achieve a high performance D/A Converter, a novel current cell with a low spurious deglitchnig circuit and a novel inverse thermomeer decoder are proposed. To verify the performance, it is integrated with $0.25{\mu}m$ CMOS 1-poly 5-metal technology. The effective chip area is $1.56mm^2$ and power consumption is about 84mW at 2.5V power supply. The simulation and experimental results show that the glitch energy is 0.9pVsec at fs=100MHz, 15pVsec at fs=300MHz in worst case, respectively. Further, both of INL and DNL are within ${\pm}$1.5LSB, and the SFDR is about 45dB when sampling, frequency, is 300MHz and output frequency is 1MHz.

• Korea journal of population studies
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• v.21 no.1
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• pp.162-183
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• 1998

This study examines the sampling bias that may have resulted from the large number of missing observations. Despite well-designed and reliable sampling procedures, the observed sample values in DSFH(Demographic Survey on Changes in Family and Household Structure, Japan) included many missing observations. The head administerd survey method of DSFH resulted in a large number of missing observations regarding characteristics of elderly non-head parents and their children. In addition, the response probability of a particular item in DSFH significantly differs by characteristics of elderly parents and their children. Furthermore, missing observations of many items occurred simultaneously. This complex pattern of missing observations critically limits the ability to produce an unbiased analysis. First, the large number of missing observations is likely to cause a misleading estimate of the standard error. Even worse, the possible dependency of missing observations on their latent values is likely to produce biased estimates of covariates. Two models are employed to solve the possible inference biases. First, EM algorithm is used to infer the missing values based on the knowledge of the association between the observed values and other covariates. Second, a selection model was employed given the suspicion that the probability of missing observations of proximity depends on its unobserved outcome.

• Tunnel and Underground Space
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• v.22 no.2
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• pp.86-92
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• 2012

Point estimate method has a less accuracy than Monte Carlo simulation that is usually considered as an exact probabilistic method, but this method still remains popular in probability-based reliability assessment in geotechnical and rock engineering, because it significantly reduce the number of sampling points and produces the statistical moments of a performance function in a reasonable accuracy. In the present study, we investigated the accuracy and applicability of point estimate methods proposed by Rosenblueth and Zhou & Nowak by comparing the results of these two methods with those of Monte Carlo simulations. The comparison was carried out for the problem of a lined circular tunnel in an elastic medium where an closed-form analytical solution is given. The comparison results showed that despite the non-linearity of the analytical solution, the statistical moments calculated by the point estimate methods and the Monte Carlo simulations agreed well with an average error of roughly 1-2%. This average error demonstrates the applicability of the two point estimate methods for the probabilistic reliability assessment of underground structures in combination with numerical analysis.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.4
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• pp.299-308
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• 2007

Purpose: The aim of this study was to develop a bioinformatics software and to test it in serum samples of papillary thyroid cancer using mass spectrometry (SELDI-TOF-MS). Materials and Methods: Development of 'Protein analysis' software performing decision tree analysis was done by customizing C4.5. Sixty-one serum samples from 27 papillary thyroid cancer, 17 autoimmune thyroiditis, 17 controls were applied to 2 types of protein chips, CM10 (weak cation exchange) and IMAC3 (metal binding - Cu). Mass spectrometry was performed to reveal the protein expression profiles. Decision trees were generated using 'Protein analysis' software, and automatically detected biomarker candidates. Validation analysis was performed for CM10 chip by random sampling. Results: Decision tree software, which can perform training and validation from profiling data, was developed. For CM10 and IMAC3 chips, 23 of 113 and 8 of 41 protein peaks were significantly different among 3 groups (p<0.05), respectively. Decision tree correctly classified 3 groups with an error rate of 3.3% for CM10 and 2.0% for IMAC3, and 4 and 7 biomarker candidates were detected respectively. In 2 group comparisons, all cancer samples were correctly discriminated from non-cancer samples (error rate = 0%) for CM10 by single node and for IMAC3 by multiple nodes. Validation results from 5 test sets revealed SELDI-TOF-MS and decision tree correctly differentiated cancers from non-cancers (54/55, 98%), while predictability was moderate in 3 group classification (36/55, 65%). Conclusion: Our in-house software was able to successfully build decision trees and detect biomarker candidates, therefore it could be useful for biomarker discovery and clinical follow up of papillary thyroid cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5551-5556
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• 2012

Cytological examination is widely used as a diagnostic tool because of the ease of collecting cells from the involved area. However, the diagnostic yield of cytological examination is unsatisfactory; the reasons include sampling error, poorly prepared samples, small numbers of malignant cells, and low grades of cellular atypia. In this study, we focused on the high infectivity of adenovirus towards epithelial cells and applied the luciferase-expressing adenoviral vector to a new cancer cell detection tool. In addition, adenoviral infectivity was enhanced by modifying viral fiber proteins. The sensitivity of the diagnostic tool was tested using the NCI-H1299 lung cancer cell line, and validated in body fluid samples from cancer patients with a variety of etiology. Results showed that the adenovirus efficiently transfected NCI-H1299 with high sensitivity. Only 10 cancer cells were sufficient for detection of luciferase signals. In body fluid samples, the adenovirus confirmed the diagnosis for malignant and benign cancer, but not in non-epithelial cell derived samples. This study provides proof-of-concept for a more reliable and sensitive diagnostic tool for epithelium-derived cancer.