• Title/Summary/Keyword: Non-mass enhancement

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Ultrafast Dynamic Contrast-Enhanced Breast MRI: Lesion Conspicuity and Size Assessment according to Background Parenchymal Enhancement

  • Soo-Yeon Kim;Nariya Cho;Yunhee Choi;Sung Ui Shin;Eun Sil Kim;Su Hyun Lee;Jung Min Chang;Woo Kyung Moon
    • Korean Journal of Radiology
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    • v.21 no.5
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    • pp.561-571
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    • 2020
  • Objective: To evaluate the clinical utility of ultrafast dynamic contrast-enhanced (DCE)-MRI compared to conventional DCE-MRI by studying lesion conspicuity and size according to the level of background parenchymal enhancement (BPE). Materials and Methods: This study included 360 women (median age, 54 years; range, 26-82 years) with 361 who had undergone breast MRI, including both ultrafast and conventional DCE-MRI before surgery, between January and December 2017. Conspicuity was evaluated using a five-point score. Size was measured as the single maximal diameter. The Wilcoxon signed-rank test was used to compare median conspicuity score. To identify factors associated with conspicuity, multivariable logistic regression was performed. Absolute agreement between size at MRI and histopathologic examination was assessed using the intraclass correlation coefficient (ICC). Results: The median conspicuity scores were 5 at both scans, but the interquartile ranges were significantly different (5-5 at ultrafast vs. 4-5 at conventional, p < 0.001). Premenopausal status (odds ratio [OR] = 2.2, p = 0.048), non-mass enhancement (OR = 4.1, p = 0.001), moderate to marked BPE (OR = 7.5, p < 0.001), and shorter time to enhancement (OR = 0.9, p = 0.043) were independently associated with better conspicuity at ultrafast scans. Tumor size agreement between MRI and histopathologic examination was similar for both scans (ICC = 0.66 for ultrafast vs. 0.63 for conventional). Conclusion: Ultrafast DCE-MRI could improve lesion conspicuity compared to conventional DCE-MRI, especially in women with premenopausal status, non-mass enhancement, moderate to marked BPE or short time to enhancement.

Utility and Diagnostic Performance of Automated Breast Ultrasound System in Evaluating Pure Non-Mass Enhancement on Breast Magnetic Resonance Imaging

  • Bo Ra Kwon;Jung Min Chang;Soo-Yeon Kim;Su Hyun Lee;Sung Ui Shin;Ann Yi;Nariya Cho;Woo Kyung Moon
    • Korean Journal of Radiology
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    • v.21 no.11
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    • pp.1210-1219
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    • 2020
  • Objective: To compare the utility and diagnostic performance of automated breast ultrasound system (ABUS) with that of handheld ultrasound (HHUS) in evaluating pure non-mass enhancement (NME) lesions on breast magnetic resonance imaging (MRI). Materials and Methods: One hundred twenty-six consecutive MRI-visible pure NME lesions of 122 patients with breast cancer were assessed from April 2016 to March 2017. Two radiologists reviewed the preoperative breast MRI, ABUS, and HHUS images along with mammography (MG) findings. The NME correlation rate and diagnostic performance of ABUS were compared with that of HHUS, and the imaging features associated with ABUS visibility were analyzed. Results: Among 126 pure NME lesions, 100 (79.4%) were malignant and 26 (20.6%) were benign. The overall correlation rate was 87.3% (110/126) in ABUS and 92.9% (117/126) in HHUS. The sensitivity and specificity were 87% and 50% for ABUS and 92% and 42.3% for HHUS, respectively, with no significant differences (p = 0.180 and 0.727, respectively). Malignant NME was more frequently visualized than benign NME lesions on ABUS (93% vs. 65.4%, p = 0.001). Significant factors associated with the visibility of ABUS were the size of NME lesions on MRI (p < 0.001), their distribution pattern (p < 0.001), and microcalcifications on MG (p = 0.027). Conclusion: ABUS evaluation of pure NME lesions on MRI in patients with breast cancer is a useful technique with high visibility, especially in malignant lesions. The diagnostic performance of ABUS was comparable with that of conventional HHUS in evaluating NME lesions.

Non-Traumatic Myositis Ossificans in the Lumbosacral Paravertebral Muscle

  • Jung, DaeYoung;Cho, Keun-Tae;Roh, Ji Hyeon
    • Journal of Korean Neurosurgical Society
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    • v.53 no.5
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    • pp.305-308
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    • 2013
  • Myositis ossificans (MO) is a benign condition of non-neoplastic heterotopic bone formation in the muscle or soft tissue. Trauma plays a role in the development of MO, thus, non-traumatic MO is very rare. Although MO may occur anywhere in the body, it is rarely seen in the lumbosacral paravertebral muscle (PVM). Herein, we report a case of non-traumatic MO in the lumbosacral PVM. A 42-year-old man with no history of trauma was referred to our hospital for pain in the low back, left buttock, and left thigh. On physical examination, a slightly tender, hard, and fixed mass was palpated in the left lumbosacral PVM. Computed tomography showed a calcified mass within the left lumbosacral PVM. Magnetic resonance imaging (MRI) showed heterogeneous high signal intensity in T1- and T2-weighted image, and no enhancement of the mass was found in the postcontrast T1-weighted MRI. The lack of typical imaging features required an open biopsy, and MO was confirmed. MO should be considered in the differential diagnosis when the imaging findings show a mass involving PVM. When it is difficult to distinguish MO from soft tissue or bone malignancy by radiology, it is necessary to perform a biopsy to confirm the diagnosis.

Vibration control in wind turbines for performance enhancement: A comparative study

  • Rezaee, Milad;Aly, Aly Mousaad
    • Wind and Structures
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    • v.22 no.1
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    • pp.107-131
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    • 2016
  • The need for a more affordable, reliable, clean and secure energy has led to explorations in non-traditional sources, particularly renewable energies. Wind is one of the cleanest energy sources that plays a significant role in augmenting sustainability. Wind turbines, as energy convertors, are usually tall and slender structures, and depending on their location (inland or offshore), they can be subject to high wind and/or strong wave loadings. These loads can cause severe vibrations with detrimental effects on energy production, structural lifecycle and initial cost. A dissipativity analysis study was carried out to know whether wind turbine towers require damping enhancement or rigidity modifications for vibration suppression. The results suggest that wind turbines are lightly damped structures and damping enhancement is a potential solution for vibration lessening. Accordingly, the paper investigates different damping enhancement techniques for vibration mitigation. The efficacy of tuned mass damper (TMD), tuned liquid column damper (TLCD), tuned sloshing damper (TSD), and viscous damper (VD) to reduce vibrations is investigated. A comparison among these devices, in terms of robustness and effectiveness, is conducted. The VD can reduce both displacement and acceleration responses of the tower, better than other types of dampers, for the same control effort, followed by TMD, TSD, and finally TLCD. Nevertheless, the use of VDs raises concerns about where they should be located in the structure, and their application may require additional design considerations.

The Matrix Effect of Biological Concomitant Element on the Signal Intensity of Ge, As, And Se in Inductively Coupled Plasma/Mass Spectrometry

  • Park, Kyung-Su;Kim, Sun-Tae;Kim, Young-Man;Kim, Yun-je;Lee, Won
    • Bulletin of the Korean Chemical Society
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    • v.23 no.10
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    • pp.1389-1393
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    • 2002
  • The non-spectroscopic interference effects that occurred in inductively coupled plasma/mass spectrometry were studied for Ge, As and Se in human urine and serum. Many biological samples contain Na, K, Cl and organic compounds, which may cause the enhancement and depression on the analyte signal. The effect of 1% concomitant elements such as N, Cl, S, P, C, Na, and K on a 100 ㎍/L germanium, arsenic and selenium signal has been investigated by ICP/MS. The interference effects were not in the same direction. It appeared that concomitant elements such as Cl, S, and C induce an enhancement effect, whereas N and P did not show any significant effect. And, Na and K caused a depression. We have found a link between the abundance of analytes and the ionization potential of concomitant elements (eV), except carbon and nitrogen.

Water transport through hydrophobic micro/nanoporous filtration membranes on different scales

  • Mian, Wang;Yongbin, Zhang
    • Membrane and Water Treatment
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    • v.13 no.6
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    • pp.313-320
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    • 2022
  • Theoretical calculation results are presented for the enhancement of the water mass flow rate through the hydrophobic micro/nano pores in the membrane respectively on the micrometer and nanometer scales. The water-pore wall interfacial slippage is considered. When the pore diameter is critically low (less than 1.82nm), the water flow in the nanopore is non-continuum and described by the nanoscale flow equation; Otherwise, the water flow is essentially multiscale consisting of both the adsorbed boundary layer flow and the intermediate continuum water flow, and it is described by the multiscale flow equation. For no wall slippage, the calculated water flow rate through the pore is very close to the classical hydrodynamic theory calculation if the pore diameter (d) is larger than 1.0nm, however it is considerably smaller than the conventional calculation if d is less than 1.0nm because of the non-continuum effect of the water film. When the driving power loss on the pore is larger than the critical value, the wall slippage occurs, and it results in the different scales of the enhancement of the water flow rate through the pore which are strongly dependent on both the pore diameter and the driving power loss on the pore. Both the pressure drop and the critical power loss on the pore for starting the wall slippage are also strongly dependent on the pore diameter.

Diagnostic Accuracy of Magnetic Resonance Imaging Features and Tumor-to-Nipple Distance for the Nipple-Areolar Complex Involvement of Breast Cancer: A Systematic Review and Meta-Analysis

  • Jung Hee Byon;Seungyong Hwang;Hyemi Choi;Eun Jung Choi
    • Korean Journal of Radiology
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    • v.24 no.8
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    • pp.739-751
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    • 2023
  • Objective: This systematic review and meta-analysis evaluated the accuracy of preoperative breast magnetic resonance imaging (MRI) features and tumor-to-nipple distance (TND) for diagnosing occult nipple-areolar complex (NAC) involvement in breast cancer. Materials and Methods: The MEDLINE, Embase, and Cochrane databases were searched for articles published until March 20, 2022, excluding studies of patients with clinically evident NAC involvement or those treated with neoadjuvant chemotherapy. Study quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. Two reviewers independently evaluated studies that reported the diagnostic performance of MRI imaging features such as continuity to the NAC, unilateral NAC enhancement, non-mass enhancement (NME) type, mass size (> 20 mm), and TND. Summary estimates of the sensitivity and specificity curves and the summary receiver operating characteristic (SROC) curve of the MRI features for NAC involvement were calculated using random-effects models. We also calculated the TND cutoffs required to achieve predetermined specificity values. Results: Fifteen studies (n = 4002 breast lesions) were analyzed. The pooled sensitivity and specificity (with 95% confidence intervals) for NAC involvement diagnosis were 71% (58-81) and 94% (91-96), respectively, for continuity to the NAC; 58% (45-70) and 97% (95-99), respectively, for unilateral NAC enhancement; 55% (46-64) and 83% (75-88), respectively, for NME type; and 88% (68-96) and 58% (40-75), respectively, for mass size (> 20 mm). TND had an area under the SROC curve of 0.799 for NAC involvement. A TND of 11.5 mm achieved a predetermined specificity of 85% with a sensitivity of 64%, and a TND of 12.3 mm yielded a predetermined specificity of 83% with a sensitivity of 65%. Conclusion: Continuity to the NAC and unilateral NAC enhancement may help predict occult NAC involvement in breast cancer. To achieve the desired diagnostic performance with TND, a suitable cutoff value should be considered.

Primary Diffuse Large B-Cell Lymphoma of the Seminal Vesicle: a Case Report

  • Kwag, Kyung Su;Jang, Suk Ki;Yeon, Jae Woo;Kwon, Kye-Won;Son, Jeong Hwan;Kim, Hyuk Jung
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.4
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    • pp.259-263
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    • 2016
  • Primary diffuse large B-cell lymphoma of the seminal vesicle is an extremely rare disorder, with only two cases reported in the English literature. Here, we present imaging findings of a case of primary diffuse large B-cell lymphoma of the seminal vesicle. On transrectal ultrasonography, the mass presented as a 3.0-cm-sized heterogeneous, hypoechoic lesion in the right seminal vesicle. Computed tomography (CT) revealed a mass with rim-like enhancement in the right seminal vesicle. On magnetic resonance imaging (MRI), the tumor showed iso-signal intensity on T1-weighted images and heterogeneously intermediate-high signal intensity on T2-weighted images. The tumor showed rim-like and progressive enhancement with non-enhancing portion on dynamic scanning. Diffusion restriction was observed in the mass. On fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging, a high standardized uptake value (maxSUV, 23.5) by the tumor was noted exclusively in the right seminal vesicle.

Adenocarcinoma of the parotid gland with calcification (석회화를 수반한 이하선내 선양암종)

  • Song Haeng-Eun;Koh Kwang-Joon
    • Imaging Science in Dentistry
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    • v.32 no.1
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    • pp.55-59
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    • 2002
  • A 78-year-old woman was referred to Chonbuk National University Dental Hospital complaining of facial palsy and palpable mass on the right parotid gland area. Clinical examination showed non-specific findings of the intraoral region, but showed asymmetrical facial appearance. Panoramic view showed a large amorphous calcified mass on the posterior to the mandibular ramus and thin cortical plate of the posterior ramus. Sialogram showed constriction of the main duct and no further filling of striated, intercalated ducts and parenchymal areas. CT scans demonstrated an irregular, infiltrating mass with slight enhancement in the right parotid gland. The mass showed necrotic areas and calcifications. Bone scan showed marked accumulation of /sup 99m/Tc-MDP on the right posterior maxilla. Microscopic findings demonstrated the minimal morphologic alterations and rare mitotic figures within tumor cells, and diagnosed as adenocarcinoma (NOS, Grade II). This report could be aid in the diagnosis of calcified lesions of the salivary gland.

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A Study on Development of Non-Powered Horse Riding Device for Enhancement of Core Muscle (코어근육군 강화를 위한 무동력 승마운동기구개발에 관한 연구)

  • Lim, Young-Tae;Kwon, Moon-Seok
    • Korean Journal of Applied Biomechanics
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    • v.25 no.3
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    • pp.353-361
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    • 2015
  • Objective : The aim of this study was to develop the non-powered horse riding device and was to evaluate the elaborate its applicability throughout static structural and transient structural analysis of the outdoor core strength exercise equipment. Method : Fifteen college students (mass: $69.55{\pm}13.38kg$, height: $1.69{\pm}5.61m$, age: $21.42{\pm}1.83yrs$) rode the powered horse riding device and 14 college students (mass: $71.12{\pm}9.74kg$, height: $1.73{\pm}3.31m$, age: $22.50{\pm}1.47yrs$) rode the non-powered horse riding device for the comparison. All motion capture data was collected at 100 Hz using six infrared cameras and the muscular activities were collected using a Delsys Trigno wireless system. The peak forward/backward lean angle, range of motion anter/posterior and vertical COM(Center of mass) movement of trunk and pelvis segment, and muscle activities of six muscles were compared between the two devices by using independent t-test (p<.05). Results : Several kinematic variables (peak forward-backward lean angle and vertical COM movement of trunk and pelvis segment, range of motion of trunk) significantly different between non-powered and powered horse riding device. The muscle activities of Rectus abdominis and External oblique of abdomen on the non-powered horse riding device were significantly greater than those of the powered device. Conclusion : It was concluded that non-power horse riding device could give the effect of core strength exercise as well as the body motion which can simulate the powered horse riding device.