• Journal of Korean Medical Science
• /
• v.33 no.53
• /
• pp.322.1-322.14
• /
• 2018

Background: Osteoprotegerin (OPG) plays protective roles against the development of vascular calcification (VC) which greatly contributes to the increased cardiovascular events in patients with chronic kidney disease (CKD). The present study aimed to find the non-traditional, kidney-related cardiovascular risk factors correlated to serum OPG and the effect of serum OPG on the arterial stiffness measured by brachial ankle pulse wave velocity (baPWV) in patients with the pre-dialysis CKD. Methods: We cross-sectionally analyzed the data from the patients in whom baPWV and the serum OPG were measured at the time of enrollment in a prospective pre-dialysis CKD cohort study in Korea. Results: Along with traditional cardiovascular risk factors such as age, diabetes mellitus, pulse pressure, and baPWV, non-traditional, kidney-related factors such as albuminuria, plasma level of hemoglobin, total $CO_2$ content, alkaline phosphatase, and corrected calcium were independent variables for serum OPG in multivariate linear regression. Reciprocally, the serum OPG was positively associated with baPWV in multivariate linear regression. The baPWV in the 3rd and 4th quartile groups of serum OPG were higher than that in the 1st quartile group after adjustments by age, sex and other significant factors for baPWV in linear mixed model. Conclusion: Non-traditional, kidney-related cardiovascular risk factors in addition to traditional cardiovascular risk factors were related to serum level of OPG in CKD. Serum OPG level was significantly related to baPWV. Our study suggests that kidney-related factors involved in CKD-specific pathways for VC play a role in the increased secretion of OPG into circulation in patients with CKD.

• Journal of Ocean Engineering and Technology
• /
• v.23 no.6
• /
• pp.23-31
• /
• 2009

The interaction of incident monochromatic waves with a bottom-mounted vertical porous circular cylinder is investigated using the framework of the three-dimensional linear potential theory. The porosity of the circular cylinder is uniform vertically but varies in the circumferential direction. By adjusting the porosities of the circular cylinder, both the wave blocking performance of a porous semi-circular breakwater and the wave responses inside a circular harbor with an entrance are applied as calculation examples. It is found that the reflected waves, wave run-up, and wave forces are significantly reduced due to wall porosity, which are positive factors for a breakwater, and the amplification factor of a circular harbor at resonant frequencies is greatly reduced by a porous sidewall.

• Journal of Ocean Engineering and Technology
• /
• v.22 no.1
• /
• pp.1-5
• /
• 2008

A 2-D Fluent-based numerical wave tank(FBNWT) capable of simulating wave propagating and overtopping is presented. The FBNWT model is based on the Reynolds averaged Naiver-Stokes equations and VOF free surface tracking method. The piston wave maker system is realized by dynamic mesh technology(DMT) and user defined function(UDF). The non-iteration time advancement(NITA) PISO algorithm is employed for the velocity and pressure coupling. The FBNWT numerical solutions of linear wave propagation have been validated by analytical solutions. Several overtopping problems are simulated and the prediction results show good agreements with the experimental data, which demonstrates that the present model can be utilized in the corresponding analysis.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
• /
• 2006.11a
• /
• pp.41-45
• /
• 2006

The fabrication process of fiber placement system of carbon fiber reinforced plastic (CFRP) requires real time process control and reliable inspection to ensure quality by preventing defects such as delamination and void. Therefore, novel non-contact inspection technique is required during the non-destructive evaluation in a fiber placement system. For the inspection of delamination in CFRP, various methods to receive laser-generated ultrasound were applied by using piezoelectric transducer, air-coupled transducer, wavelet transform and scanning laser ultrasonic technique. Laser-generated ultrasound was received with a conventional piezoelectric sensor in contacting manner. Then signal characteristics due to defects were analyzed to find a factor for detecting defects. Air-coupled transducer was used for reception of laser-generated guided wave using linear slit array in order to generate high frequency guided wave. And line scan technique was used to confirm the capability of on-line application. The high frequency component of laser-generated guided wave received with piezoelectric sensor disappeared after propagating through delamination region. Nevertheless, it was failed to receive high frequency guided wave in using air-coupled transducer. The first peak of the frequency spectrum under 100kHz in the delamination region is higher than in the sound region. By using this feature, the line scanned frequency data were acquired in fully non-contact generation and reception of ultrasound. This method was proved as useful technique for detecting delamination in CFRP.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.23 no.5
• /
• pp.335-344
• /
• 2011

A curvilinear non-hydrostatic free surface model is developed to investigate nonlinear wave interactions in a circular channel. The proposed model solves the unsteady Navier-Stokes equations in a three-dimensional domain with a pressure correction method, which is one of fractional step methods. A hybrid staggered-grid layout in the vertical direction is implemented, which renders relatively simple resulting pressure equation as well as free surface closure. Numerical accuracy with respect to wave nonlinearity is tested against the fifth-order Stokes solution in a two-dimensional numerical wave tank. Numerical applications center on the evolution of nonlinear waves including diffraction and reflection affected by the curvature of side wall in a circular channel comparing with linear waves. Except for a highly nonlinear bichrmatic wave, the model's results are in good agreement with superimposed analytical solution that neglects nonlinear effects. Through the numerical simulation of the highly nonlinear bichramatic wave, the model shows its capability to investigate the evolution of nonlinear wave groups in a circular channel.

• Journal of the Korea Concrete Institute
• /
• v.11 no.4
• /
• pp.157-167
• /
• 1999

Among several non-destructive testing methods, ultrasonic pulse velocity method and rebound index method have been widely used for the evaluation of concrete strength. However, such methods might not provide accurate estimated results since factors influencing the relationship between strength and either ultrasonic pulse velocity or rebound index are not considered. In this paper, the evaluation method of concrete strength using rod-wave velocity measured by impact-resonance method is proposed. A basic equation is obtained by the linear regression of velocity vs, strength data at specific age and then, aging factor is employed in the equation to consider the difference of the increasing rate between wave velocity and strength. Strengths predicted by the proposed equation agree well with test results. Furthermore, the combined method of rod-wave velocity and rebound index is proposed.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2002.11b
• /
• pp.505-510
• /
• 2002

The attenuation of waves transmitted through non-conservative joints that are shown in many paractical structures, is affected by the impedance and the orientation of the joint. In this paper, the joints between plate structures are assumed to be modeled as linear spring-dashpot systems and the transmission and reflection of vibration energy in the medium to high frequency ranges are investigated. The calculated power transmission and reflection coefficients are applied to the PFA method for the prediction of energy density and intensity in structures.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2002.11a
• /
• pp.353.2-353
• /
• 2002

The attenuation of waves transmitted through non-conservative joints that are shown in many practical structures, is affected by the impedance and the orientation of the joint. In this paper, the joints between plate structures are assumed to be modeled as linear spring-dashpot systems and the transmission and reflection of vibration energy in the medium to high frequency ranges are investigated. (omitted)

• Ocean and Polar Research
• /
• v.24 no.3
• /
• pp.237-247
• /
• 2002

We report all sky camera and Fabry-Perot interferometer (FPI) observations of mesospheric gravity waves and a 12-hour wave at Resolute $(75^{\circ}N)$ and a joint observation of 10-hour wave with Eureka $(80^{\circ}N)$. All sky camera observations showed a low occurrence of mesosphere gravity waves during equinoxes, which is similar to the mid-latitude region. A slightly higher occurrence near solstice appears to indicate that gravity waves are not filtered out by the neutral wind in the winter. The FPI observation of a 12-hour wave showed amplitude variations from day to day. The phase of the wave is mostly stable and consistent with the GSWM prediction in the winter. The phase shifts with season as predicted by the GSWM. Four events of the 12-hour wave were found in spring with amplitudes larger than the GSW predictions. The FPls at Resolute and Eureka also observed a wave with period close to 10 hours. The 10-hour wave maybe the result of the non-linear interaction between the semi-diurnal tide and the quasi-two day wave. Further studies are under way. Overall, the combined Resolute and Eureka observation have revealed some new fractures about the mesospheric gravity wave, tidal wave, and other oscillations.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.2 no.2
• /
• pp.75-82
• /
• 1990

A Wave transformation including wave breaking in shallow water region is a non-linear and discontinuous Phenomenon. Therefore, a so-called individual wave analysis (or a wave by wave analysis) rather than spectral approach seems to be adequate to investigate the wave transformation in such regions. In this study, a theoretical joint distribution of wave height, period and wave direction of zero-down crossing waves, which is required in the individual wave analysis in the shallow water region, is derived based on the hypothesis that sea surface is a Gaussian stochastic process and that a band-width of energy spectra is sufficiently narrow. The derived i oint distribution is found to be an effective measure to investigate characteristics of three-dimensional random wave field in shallow water through field measurements.