• Journal of Pharmaceutical Investigation
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• v.28 no.1
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• pp.43-50
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• 1998

Niosomes are vesicles formed from synthetic non-ionic surfactants, offering an alternative to chemically unstable and expensive liposomes as a drug carrier. Non-ionic surfactant and cholesterol mixture film leads to the formation of vesicular system by hydration with sonication method. The formation of niosome was ascertained by negative staining of TEM. The entrapment efficiency of niosomal suspension was gradually increased with increasing the ratio of cholesterol to surfactant. It was found that the niosome with 6 : 4 (polyoxyethylene 2-cetyl ether: cholesterol) ratio was more stable than those with other ratios. The topical application of acyclovir(ACV) in the treatment of herpes simplex virus type 1(HSV-1) skin disease has a long history. There are an increasing number of reports, however, in which topical ACV therapy is not as effective as oral administration. Lack of efficacy with topical ACV has been hypothesized to reflect the inadequate delivery of drug to the skin. We investigated the permeation of niosome containing $[^{3}H]ACV$ in hairless mouse skin using Franz diffusion cell model. Permeation coefficient(P) of aqueous ACV was $6.7{\times}10^{-4}\;(cm/hr)$ and that of ACV in niosome was $23.4{\times}10^{-4}\;(cm/hr)$, suggesting about 3.5 times increase in the transdermal permeation.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.19 no.2
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• pp.133-141
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• 2007

The drag reduction (DR) and heat transfer efficiency reduction (HTER) of nonionic surfactant according to the fluid velocity, temperature and surfactant concentration were investigated experimentally. For this study, several kinds of new surfactant which contains amine-oxide and betaine were developed. And experimental apparatus equipped with two water storage tanks temperature controlled, pumps, testing pipe network, two flowmeters, two pressure gauges, heat exchanger, and data logging system was built. Results showed that existing alkyl ammonium surfactant (CTAC) had DR of $0.6{\sim}0.8$ for $1,000{\sim}2,000\;ppm$ in fluid temperature of $50{\sim}60^{\circ}C$ and had very low DR in fluid temperature over $70^{\circ}C$. And new amino oxide and betaine surfactant (SAOB) had lower DR in fluid temperature of $50{\sim}60^{\circ}C$ compared with CTAC but in fluid temperature of $70{\sim}80^{\circ}C$ DR was $0.6{\sim}0.8$ for 1$1,000{\sim}2,000\;ppm$.

• Journal of the Korean Chemical Society
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• v.58 no.4
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• pp.351-358
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• 2014

Anionic (sodium lauryl sulphate, NaLS) cationic (cetyl ammonium bromide, CTAB) and non-ionic (Tween-80) surfactants have been found to inhibit the rate of oxiadation L-proline and L-methionine by alkaline $KMnO_4$. A first order dependence of rate of oxidation was observed with respect to $MnO_4{^-}$. The order of reaction in substrate and alkali was found to be fractional nearby 0.65 and 0.55 in Aminoacid and $OH^-$, respectively. An aggregation/association between $MnO_4{^-}$ and surfactant has been confirmed spectrophotometrically. A mechanism, involving kinetically inactive [$MnO_4{^-}$ surfactant] aggregate and consistent with kinetic data, has been proposed. The effect of surfactants has been discussed in terms of hydrophobic and electrostatic interactions.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2000.10a
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• pp.653-655
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• 2000

Alumina-surfactant mesostructures have been synthesized with the $Al_{13}$-Keggin cation prepared by Al(N $O_3$)$_3$.9$H_2O$ solution with NaOH solution in the presence of a non-ionic surfactant at room temperature. The synthesized samples had the hexagonal structure similar to MCM-41 type materials. These samples have been characterized by X-ray diffraction and thermal analysis(TG). The samples prepared from OH/Al ratio 1.5 and 2.0 were well-crystalline mesostructures, but the sample from OH/Al ratio 2.5 was not. Also, The d$_{100}$ value decreased slightly from 38 to 36 according to the OH/Al mole ratio. These results could be explained that Keggin ion depended on the OH/Al molar ratio and pHpH

• Journal of the Korean Society of Clothing and Textiles
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• v.2 no.1
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• pp.151-155
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• 1978

General components and detergency of commercial shampoos have been investigated and the results are summerized in the following. Shampoos were analyzed for surfactants and additives by KS method and surfactants were confirmed by T.L.C. Considerable differences in amounts of non volatiles and surfactants were found. Three of them contain either lanoline or sterols as additives and in the three. propylene glycol was found in their liquid part. It was shown that predominant sufactant was anionic and in all, except one. a little ampholytic surfactant was detected. But, contrary to forecast, in only one a little of non ionic surfactant was detected. Detergency of shampoos was examined using artificially soiled wool muslin. Considerable difference was found, and all shampoos showed higher detergency than a synthetic powder type detergent for textiles. There were no significant correlation between detergency and amount of surfactants or suspending power of detergents.

• Journal of Magnetics
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• v.15 no.3
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• pp.112-115
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• 2010

We have investigated a surfactant-assisted sonochemical approach to produce monodisperse $Fe_3O_4$ nanoparticles (NPs). The non-ionic surfactant Igepal CO-520 (Poly(oxyethylene)(5) nonylphenyl ether) has been used for the preparation of NPs and the effects on the NP size, size distribution, and magnetic properties have been studied. The $Fe_3O_4$ NPs were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), and vibrating sample magnetometry (VSM). The results reveal that the NPs prepared by a Igepal CO-520-assisted sonochemical method exhibit a narrow range of size distributions and a high monodispersity compared to the NPs from the conventional sonochemical method. The analysis of NPs prepared in the presence of the surfactant suggested that it could be used not only as a protector to prevent the oxidation of Fe (II), but also as a controller to vary the size of the NPs.

• Textile Coloration and Finishing
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• v.8 no.1
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• pp.83-89
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• 1996

Carbon black has been used as a particulate soil to prepare artificial soiled fabrics for detergent study but it has two major defects. The one is the difficulty of quantitative analysis of carbon black for evaluate the detergency, the other is that there is no reliable correlation between the removal of carbon black and oily soil which is the major component of natural soil. In this study ferric oxinate was used as a particulate soil since it is in black color and can be soiled on fabric by suspension in water or by solution in chloroform and it is easily analysed quantitatively by extracting it from soiled fabric with chloroform to get correct value of soil removal. The characteristics of soil removal of ferric oxinate were compared with that of carbon black and Sudan black, an oil soluble dye, which had been proved that it's detergency correlated with that of oily soil The soil removal of ferric oxinate and Sudan black estimated from quantitative analysis and from K/S value were in good agreement whereas the result calculated by simple reflectance was consistently low. The soil removal of ferric oxinate was exceeded from that of carbon black without regard to surfactants, Triton and Las, but the effect of washing conditions such as temperature and washing time on soil removal of both soils with different suffactants showed no considerable difference. Though the soil removal of Sudan black was little effected by the conditions, the soil removal in Triton exceeded considerably that of in Las, which is the characteristic of oily soil. Thus the soil removal of Sudan black was in good agreement with ferric oxinate in Triton, a non-ionic surfactant, and with carbon black in Las, an artionic surfactant. We concluded that ferric oxinate is a more realistic model particulate soil for artificial soiled cotton fabric washed with non-ionic surfactant than carbon black.

• Proceedings of the Korean Geotechical Society Conference
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• 2003.03a
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• pp.597-604
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• 2003

In the soil washing process, the contaminants are usually removed by abrasion from soil particles using mechanical energy and water However, organic contaminants with low water solubility like polycyclic aromatic hydrocarbons (PAH) are remained on soil particles. Previous studies have shown that surfactant possessing amphipathic activity enhances the solubility of organic materials. For this reason solutions with surfactants have been used to improve removal of organic contaminants on soil washing process. But, in this manner, many problems were found like complete loss of surfactants and additional contamination by surfactant. The remediation method using microemulsion has been introduced to overcome these disadvantages. In this case, surfactants are recycled by phase separation of microemulsion after remediation. In microemulsion process, the surfactant will be recycled by phase separation of the microemulsion into a surfactant-rich aqueous phase and an oil phase after extraction. That is why remediation concept applying microemulsion as washing media has been Introduced. Suitable microemulsion have to be used in order to have the chance of refilling the soil after decontamination and to avoid any risk due to toxicity. The purpose of this research is to evaluate effect of microemulsion to remediation of contaminated soil. We performed test with various organic contaminants like Pyrene and BTEX, also compared efficiency of remediation in microemulsion process with soil washing

• Fire Science and Engineering
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• v.16 no.3
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• pp.61-70
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• 2002

A fire extinguishing agent containing non-ionic surfactant which is environmentally friendly and low cost was prepared and tested its characteristics and fire fighting performance. Ethoxylated sorbitol septaoleate, containing 40 moles of ethylene oxide as the primary surfactant, linear ethoxylated secondary alcohol, containing 7-11 moles ethylene oxide as the secondary surfactant, and ethoxylated sorbitol trioleate, containing 40-50 moles of ethylene oxide were used in the agent. It is demonstrated that the water solution containing 6 wt％ agent is capable to extinguish gasoline fire when it is put into the fire four times as much as gasoline. According to the field test of class B fire with a unit 1, it is found that the fire fighting performance is directly proportional to the concentration of surfactant in the agent.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2008.04a
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• pp.181-183
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• 2008

Four different subtilisins of protease were investigated to see their effects on the cleaning activity. The cleaning solution was formulated with various non-ionic surfactants and other additives such as propylene glycol, triethanolamine, pH balancer etc. to evaluate their effect on enzyme activity as well. Evaluation of formulated cleaning solution was carried under K0120 using pre-soiled textiles from EMPA. The results showed that the cleaning activity on soil removal was not severly influenced by surfactant but the enzyme mostly. In addition, the activity of enzymes was not much affected by the type of surfactants as long as the surfactants were non-ionic. Liquinase among the four enzymes used in this study showed the best performance on soil removal, especially blood stain.