• The Plant Pathology Journal
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• 제39권4호
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• pp.309-318
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• 2023

Huanglongbing (HLB) is one of the most destructive diseases in citrus, which imperils the sustainability of citriculture worldwide. The presumed causal agent of HLB, 'Candidatus Liberibacter asiaticus' (CLas) is a non-culturable phloem-limited α-proteobacterium transmitted by Asian citrus psyllids (ACP, Diaphorina citri Kuwayama). A widely adopted method for HLB diagnosis is based on quantitative real-time polymerase chain reaction (qPCR). Although HLB diagnostic qPCR provides high sensitivity and good reproducibility, it is limited by time-consuming DNA preparation from plant tissue or ACP and the requirement of proper lab instruments including a thermal cycler to conduct qPCR. In an attempt to develop a quick assay that can be deployed in the field for CLas detection, we developed a real-time loop-mediated isothermal amplification (rt-LAMP) assay by targeting the CLas five copy nrdB gene. The rt-LAMP assay using various plant sample types and psyllids successfully detected the nrdB target as low as ~2.6 Log10 copies. Although the rt-LAMP assay was less sensitive than laboratory-based qPCR (detection limit ~10 copies), the data obtained with citrus leaf and bark and ACP showed that the rt-LAMP assay has >96% CLas detection rate, compared to that of laboratory-based qPCR. However, the CLas detection rate in fibrous roots was significantly decreased compared to qPCR due to low CLas titer in some root DNA sample. We also demonstrated that the rt-LAMP assay can be used with a crude leaf DNA extract which is fully deployable in the field for quick and reliable HLB screening.

• Nutrition Research and Practice
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• 제17권5호
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• pp.997-1006
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• 2023

BACKGROUND/OBJECTIVES: Asthma and allergic rhinitis (AR) are closely related and considered as allergic respiratory diseases (ARD), and their prevalence has recently increased. Data on the association of dietary antioxidant vitamin intake with asthma and AR in adults are limited. The present study aimed to investigate the associations of vitamin A and C intake with asthma, AR, and all cases of both diseases in young adults who participated in a cross-sectional national survey, with the use of high-sensitivity C-reactive protein (hs-CRP) level as an effect modifier. SUBJECTS/METHODS: This study included 6,293 male and female adults aged 20-49 years from the Korea National Health and Nutrition Examination Survey (KNHANES) conducted between 2016 and 2018. The questionnaire-based reports on asthma and AR diagnosis were used to determine outcome variables. Further, 24-h recall data on dietary vitamin A and C, carotene, and retinol intake were acquired. Logistic regression analysis was performed to calculate odds ratios (ORs) and 95% confidence interval (CI). RESULTS: Dietary vitamin C intake was inversely associated with asthma prevalence among participants with hs-CRP levels (≥ 1 mg/L); the OR of asthma prevalence was 0.27 (95% CI, 0.08-0.84) for participants with vitamin C consumption ≥ 75 mg/day compared with those consuming < 20 mg/day. Similar association analyses limiting to non-users of dietary supplements were performed to rule out the potential effects of supplement intake on the outcomes; results showed a stronger association. However, the association between vitamin C and asthma was not significant in participants with hs-CRP levels < 1 mg/L; the OR of asthma was 1.44 (95% CI, 0.66-3.16) for participants with vitamin C consumption ≥ 75 mg/day compared with those consuming < 20 mg/day. Vitamin C intake was not associated with AR. Moreover, there was no association between vitamin A intake and neither asthma nor AR. CONCLUSIONS: These findings suggest that higher vitamin C intake may play a potential role in reducing asthma prevalence. Nevertheless, further studies should be conducted to evaluate whether this association is causal.

• Journal of Preventive Medicine and Public Health
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• 제57권3호
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• pp.242-251
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• 2024

Objectives: The aim of this study was to analyze the relationship between objective social isolation (SI) and unmet medical needs (UMN) in adults aged 19 and older. Methods: A cross-sectional analysis was conducted of 208 619 adults aged 19 and older, excluding missing data, using the 2019 Korea Community Health Survey. To analyze the association between objective SI and UMN, the chi-square test and logistic regression analysis were performed. Results: The prevalence of UMN was 1.14 times higher (odds ratio [OR], 1.14; 95% confidence interval [CI], 1.06 to 1.23) among those with SI than among those without SI, and the OR for groups with 5 SI types was 2.77 (95% CI, 1.86 to 4.12) compared to those with no SI types. In addition, a stratified analysis by age group showed that the association between SI and UMN existed even in groups under 64 years old. However, among those aged 65 and older, SI was associated with an OR of 1.53 (95% CI, 1.37 to 1.71) for UMN compared to non-SI. As the number of SI types increased, the prevalence of UMN also increased, indicating a strong association between SI and UMN in older adults. Conclusions: This study found that individuals with SI experienced UMN due to fear and anxiety about interpersonal relationships. Therefore, based on the results of this cross-sectional study, it is necessary to investigate the causal relationship between SI and UMN through future longitudinal data.

• International Journal of Computer Science & Network Security
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• 제24권5호
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• pp.11-20
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• 2024

While artificial neural networks are adept at identifying patterns, they can struggle to distinguish between actual correlations and false associations between extracted facial features and criminal behavior within the training data. These associations may not indicate causal connections. Socioeconomic factors, ethnicity, or even chance occurrences in the data can influence both facial features and criminal activity. Consequently, the artificial neural network might identify linked features without understanding the underlying cause. This raises concerns about incorrect linkages and potential misclassification of individuals based on features unrelated to criminal tendencies. To address this challenge, we propose a novel region-based training approach for artificial neural networks focused on criminal propensity detection. Instead of solely relying on overall facial recognition, the network would systematically analyze each facial feature in isolation. This fine-grained approach would enable the network to identify which specific features hold the strongest correlations with criminal activity within the training data. By focusing on these key features, the network can be optimized for more accurate and reliable criminal propensity prediction. This study examines the effectiveness of various algorithms for criminal propensity classification. We evaluate YOLO versions YOLOv5 and YOLOv8 alongside VGG-16. Our findings indicate that YOLO achieved the highest accuracy 0.93 in classifying criminal and non-criminal facial features. While these results are promising, we acknowledge the need for further research on bias and misclassification in criminal justice applications

• 한국IT서비스학회지
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• 제23권3호
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• pp.55-63
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• 2024

To grasp the structure of an industry and monitor its changes, it is essential to utilize relevant statistics. Various statistics are being compiled regarding the software (SW) industry, presenting diverse numerical values. However, without a precise understanding of the scope and measurement methods inherent to each statistic, gaining a rigorous understanding of the industry's structure and evolving trends becomes challenging. Moreover, significant discrepancies between similar statistics often lead to confusion among users. In the software (SW) industry, key statistics commonly used include SW production value and SW market size. As of 2022, the annual domestic SW production value is reported as 77.4 trillion KRW (based on ICT Survey), while the SW market size for the same year is stated as 38.5 trillion KRW (according to IDC data). Although production value and market size may seem conceptually similar, there is approximately a twofold difference between the figures provided. Without understanding the meanings of each statistic and the differences between them, there are limitations in utilizing these statistics effectively. While statistics are utilized for various purposes such as policy development or causal analysis of policy using statistical raw data, research that presents and analyzes the precise meanings and limitations of each SW-related statistic is virtually non-existent. Thus, this study aims to compare and analyze the methodologies and differences among key statistics used to represent the SW industry: SW production value, SW market size, and SW GDP statistics. Through this analysis, the goal is to contribute to a better understanding of the SW industry's structure and enable more accurate and rigorous utilization of relevant statistics.

• 벤처창업연구
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• 제18권4호
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• pp.207-222
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• 2023

대부분의 대학은 취업률 향상을 위하여 산헙혁력선도대학(LINC) 선정 여부와 상관없이 학생들의 취·창업역량강화 프로그램을 운영하고 있다. 특히 비수도권대학의 경우 취업률 향상을 위하여 사활을 걸고 있다. 취업률에 절대적으로 영향을 미치는 대학설립유형과 대학소재지에 대한 한계를 극복하기 위하여, 취·창업역량강화를 위하여 기업가정신 함양을 위한 창업교육·지원 프로그램을 운영하고 있으며, 지역 및 기관과 연계한 PBL(Problem Based Learning) 컨셉이 반영된 캡스톤디자인과 현장실습 프로그램을 상시 운용하고 있다. 기존 연구에서는 산헙혁력선도대학(LINC)을 중심으로 효과성 검증에 관한 연구는 수행되었으나, 공시지표를 기반으로 취업률에 미치는 요인으로서 대학요인, 창업교육·지원, 산학연계교육 요인 모두를 대상으로 한 종단연구 사례는 보고되지 않았다. 본 연구는 취업률에 미치는 요인으로 대학요인, 창업교육·지원, 산학연계교육에 대하여 최근까지 공개된 2018년부터 2020년까지 대학공시지표를 기반으로 조건을 만족시키는 116개 대학을 대상으로 51개의 산학협력선도대학(LINC) 참여대학과 64개의 비참여대학 집단간 차이분석을 하였다. 또한 공시지표의 한계로 인하여, 참여 학생의 중복참여에 대한 이력 정보가 없는 점을 고려하여 취·창업역량강화 프로그램에 장기간 노출된다면 역량강화를 통한 취업률에 영향을 미칠 것이라는 노출효과(Exposure Effect)이론을 기반으로 종단적 인과관계 분석을 통하여 2017년부터 2021년까지 2차 사회맞춤형 산학협력 선도대학 육성사업(LINC+)의 효과성을 검증하였다. 연구결과 사회맞춤형 산학협력 선도대학 육성사업(LINC+)의 창업교육·지원 및 산학연계교육 프로그램은 취업률에 영향을 미치지 않는 것으로 나타났다. 종단적 인과관계 분석결과 기존 대학요인으로 수도권대학이 비수도권대학보다 여전히 취업률이 높으며, 사립대학이 국립대학보다 취업률이 높은 것을 재확인하였다. 취·창업역량강화 프로그램 중 창업강좌 이수자수, 캡스톤디자인 이수자수, 캡스톤디자인 지급액, 전담교직원수는 취업률에 연도별 부분적으로 영향을 미치며, 현장실습은 연도별로 전혀 영향을 미치지 않으며, 취·창업역량강화 프로그램의 장기간 노출이 취업률에 영향을 미치지 않음을 확인하였다. 그러므로, 대학의 취업률 향상을 위해서는 비수도권, 국·공립대의 한계를 극복해야만 함을 재확인하였다. 이를 극복하기 위한 취·창업역량강화 프로그램으로서 창업강좌 참여를 통하여 기업가정신의 강화와 PBL(Problem Based Learning) 컨셉이 강화된 캡스톤디자인 프로그램의 적극적인 도입 및 확신이 중요하며, 현장실습 프로그램이 취업률 향상에 도움이 되기 위해서는 전반적인 학사제도 및 조직의 재정비를 통한 내실 있는 프로그램 진행이 요구된다.

• 동의신경정신과학회지
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• 제2권1호
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• pp.3-18
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• 1991

Serotonin was chemically identified as 5-hydrowytryptamin which occurs in plants, animals, and human beings. The end product of metabolism was excreted as 5-HIAA in urine. Many scientists, specially biochemist and psychiatrist reported that the change of serotonin concentration caused mental disorder and pathological condiions such as schizophrenia and carcinoid. This study was carried out to observe the urinary 5-HIAA excretion rates changed by three recipes treatment (Kamisoyosan, Ondamtang, kalgunhaegitang) according to the classification of endogenous, exogenous and non-exo-endogenous, causes of disease. The urinary 5-HIAA excretion rates before and after three recipes treatment on normal groups divided into three groups on the basis of physical constitutional differences and on patients groups, divided into three groups according to the causal factor were measured. The results were as follows; 1. The urinary 5-HIAA volume of patients groups appeared non-exoendogenous, endogenous, exogenous causes of disease in order of three causative classification. 2. The urinary 5-HIAA volume of Normal groups was $2.50{\pm}088mg/24hrs$(range $0.30{\sim}6.90mg/24hrs$) 3. Thr urinary 5-HIAA volume was $3.70{\pm}0.89mg/24hrs$(range $0.90{\sim}6.50mg/24hrs$) before kamisoyosan treatment and $3.20{\pm}0.72mg/24hrs$ (range $0.80{\sim}6.20mg/24hrs$) after the treatment. 4. The value was $2.60{\pm}0.10mg/24hrs$ (range $0.60{\sim}6.50mg/24hrs$) before Ondamtange treatment and $2.00{\pm}0.12mg/24hrs$(range $0.20{\sim}6.10mg/24hrs$) after the treatment. 5. The value was $4.30{\pm}0.75mg/24hrs$(range $0.92{\sim}6.50mg/24hrs$) before kalgunhaegitang treatment and $3.10{\pm}0.10mg/24hrs$(range $0.80{\sim}5.80mg/24hrs$) after the treatment. Considering the above-mentioned the study on the changes of urinary 5-HIAA volume will make a significant contribution to the diagnosis and the evaluation of therapeutic effect successive research and modified application will be in need.

• 유통과학연구
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• 제14권5호
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• pp.71-80
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• 2016

Purpose - In case of automobile parts, there has been a lot of progress in the study on supplier development plans and SCM in industrial progress study as well as on the relationship between ERP and SCM. But supplier development program providers have researched on SCM performance in accordance with the interests of the supplier development program most, thus, buyers were knowledgeable about the earlier program performance. Therefore, the purpose of this study is to prove correlation factor, supplier factor, purchaser factor affecting SCM performance and ERP activating diffusion through the process of supplier development. Supplier development maturity formation model is considered important variables as mediators related to the procedure. Finally, the performance formation model of the supplier development maturity through supplier development factor would be presented as the outcome of this study. Research design, data, and methodology - Data gathering was as follows: questionnaires were delivered to 87 companies that have business connection with H Company. The empirical research to test our hypothesis was grounded on statistical analysis (adapting SPSS 19.0 & AMOS 19.0). The hypothesis is that the supplier development factor variables consist of correlation factor, supplier factor, purchaser factor, and have non-negative effects on the next variables: mediators such as supplier development maturity; and the supplier development maturity variables have a positive effect on the next variables: ERP activating diffusion, ERP activating diffusion has a non-negative effect on supply chain performance. We experimented the hypothesized model using path analysis with latent variables. Results - First, it was known that cooperation

, reliability

, comprehension on the purpose of SDP

, adaptation of change

, knowledge transfer program

, have significant positive effects on supplier development maturity. Second, supplier development maturity has positive effects significantly on ERP activating diffusion

. Finally, the causal relationships from ERP activating diffusion to SCM performance were significantly accepted. Its significance, as through the hypotheses, presented a structural model for the elaboration, suppliers develop maturity, and ultimately SCM performance that affect ERP leveraging spread beyond the concept of maturity of information system. Therefore, it was a mainstay of research on the existing ERP has they believed. Conclusion - First, with the fast changes in business circumstances, company should get the right information to implement SCM appropriately. For successful SCM, firms should understand the supplier development maturity formation and ERP activating diffusion. Second, supplier development factor has significant effects on supplier development maturity. Third, mediator such as supplier development maturity significantly affects ERP activating diffusion. Finally, ERP activating diffusion has significant impacts on SCM performance. This study makes a meaningful contribution to further appreciation on how supplier development maturity formation affects SCM performance. This study shows implications. First, there would not have been dealt with introducing the concept of supplier development maturity. Second, through empirical analysis and provider factors, the providers will develop the maturity that affect interactive factors between purchaser and supplier.

• 한국항해항만학회지
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• 제44권1호
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• pp.44-52
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• 2020

세계적인 장기경기침체 속에서 보다 정확한 물동량 예측은 항만정책 수행에 중요하다. 따라서, 본 연구에서는 부산항 컨테이너 물동량(수출입화물과 환적화물)을 단변량 모형인 ARIMA 뿐만 아니라 인과관계가 있을 것으로 예상되는 경제규모(한국, 중국, 미국의 국내총생산), 금리수준 그리고 경기변동을 고려한 벡터자기회귀모형과 벡터오차수정모형을 활용하여 추정하고 비교하였다. 측정자료는 2014년 1월부터 2019년 8월까지 월별 부산항 컨테이너 물동량이다. 분석결과에 의하면, 수출입물동량 시계열은 비교적 안정적(stationary)이어서 VAR에 의해 추정하였고 환적화물은 불안정적(non-stationary)하지만, 경제규모, 금리 및 경기변동과 공적분(장기적인 균형관계)를 띠고 있어 VEC모형으로 추정하였다. 추정결과, 안정적인 수출입화물 추정에서는 단변량 모형인 ARIMA가 우수하고 추세가 있는 환적화물은 다변량모형인 VEC모형이 보다 예측력이 우수한 것으로 나타나고 있다. 특히 수출입화물은 우리나라 경제규모와 관련이 있고, 환적화물은 중국과 미국 경제규모와 밀접한 관련이 있다. 또한 중국 경제규모가 미국에 비하여 더 밀접하게 나타나고 있어 환적화물 증대전략에 시사점을 주고 있다.

• 대한안전경영과학회지
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• 제10권4호
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• pp.297-307
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• 2008

At the spots of enterprises experiencing rapid environmental changes, necessity for ceaseless managemental innovation is raised. We can't deny that management quality is also a part of such managemental innovation. Introduction of management quality by an organization is different from introduction of other individual innovative techniques. Management quality is not one time project but complete historical change program to be pursued continuously. Furthermore, it must be understood as a strategic 'Quality Journey' looking for far future of an organization. Malcolm Baldrige Model has been increasingly used in Korea as a global standard for management quality. The model, however, has shown a number of limitations in application due to nonsystematic elements in the implementation process. The deployment process of the model should be detailed through a real world case study. In this research, we proposed a quality evaluation standard model which is suitable for the Korean public enterprise based on the Malcolm Baldrige Non-profit Criteria, and examined the model. A 7-Point Likert Scale was used based on the seven categories within the 2007 Malcolm Baldrige Non-profit Criteria: Leadership, Strategic Planning, Customer and Market Focus, Management Analysis and Knowledge Management, Workforce Focus, Process Management, and Results. Furthermore, we analysed the validity and causal relationship among the factors within the model. Through the above case study, following common factors for successful Malcolm Baldrige Model have been derived. The following is a summary of the results of this study. First, for Malcolm Baldrige Model management, needs powerful support Leadership. Second, for Malcolm Baldrige Model management, needs systematic Strategic Planning. Third, for Malcolm Baldrige Model management, needs the continuous Customer and Market Focus. Fourth, for Malcolm Baldrige Model management, needs systematic Measurement Analysis and Knowledge Management. Five, for Malcolm Baldrige Model management, needs systematic Workforce Focus. Six, for Malcolm Baldrige Model management, needs systematic Process Management. The finding are surely necessary factors to arrange the human resource management for upgraded management quality, those factors help to explain why all enterprises consider human resource as the strategic view.