• Journal of Preventive Medicine and Public Health
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• v.40 no.1
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• pp.16-22
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• 2007

Objective : The purpose of this study was to evaluate the levels of DNA damage in human lymphocytes caused by smoking and other lifestyle factors. Methods : The study population consisted of 173 normal healthy male adults from 21 to 59 years old. The demographic and lifestyle variables were obtained from administered questionnaires. The level of lymphocytic DNA damage in the peripheral blood was evaluated by the Comet assay. Statistical analyses were done by general linear model analysis and Dunnett's multiple comparison. Results : The difference in DNA damage between smokers and non-smokers was statistically significant. The means for the Tail%DNA were found to be 10.48 in the current smokers and 9.60 in the non-smokers (p < 0.05). The tail moment means were 1.58 and 1.45 (p < 0.05) for the current smokers and non-smokers, respectively. The number of cigarettes smoked per day did not result in a significant difference in the level of DNA damage among the smokers. Other lifestyle factors such as age, and drinking and exercise habits were not related to DNA damage. Conclusions : The DNA damage in the lymphocytes of smokers was found to be significantly higher than that for non-smokers. However, the number of cigarettes smoked per day was not related to DNA damage. Further study is needed to evaluate the relationship between the amount of smoking and level of damage to DNA. In addition, the status of DNA repair activities should be assessed.

• Journal of the Korean Dietetic Association
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• v.4 no.2
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• pp.168-177
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• 1998

It has been reported that cigarette smoking increases free radical generation, which can also increase lipid peroxides and deplete antioxidants. The purpose of this study was to determine whether cigarette smoking and other lifestyle choices may affect serum lipid peroxide concentrations, serum antioxidant concentrations such as tocopherol and vitamin C, and serum antioxidant enzyme activity such as glutathione peroxidase and superoxide dismutase. Dietary intakes were assessed by 24-hour recall and survey questionnaires from 48 male non-smokers and 52 male smokers. Overnight fasting blood was collected and measured for individual antioxidant status. The daily vitamin C intakes of smokers tended to be lower than those of non-smokers, and the intakes of both groups were under the Recommended Daily Allowance (RDA). Vitamin E intake was sufficient for smokers and non-smokers. Serum lipid peroxide concentrations were no difference among all subjects. The serum $\alpha$-tocopherol concentrations of all subjects were in a normal range, and they were highest in mild smokers (p<0.05). Mean serum vitamin C levels were lowest in heavy smokers (p<0.05). The activities of serum glutathione peroxidase and superoxide dismutase were not significantly different in smokes and non-smokers. In conclusion, smoking did not increase oxidative stress in heathy young men. However, it is desirable for heavy smokers to consume more vitamin C than the RDA sine their serum vitamin C concentrations are relatively low.

• Journal of the Korean Dietetic Association
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• v.8 no.3
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• pp.260-268
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• 2002

The purpose of this study was to compare food behaviors, nutrient intake, clinical symptoms, and hematological findings by smoking status. Among the third grade male students from a high school in Jinchun-kun, 31 smokers and 31 nonsmokers participated in this study. A self-administered questionnaire was used to investigate food behaviors and clinical symptoms. Nutrient intake data were collected by 24-hour recall method. Blood sample was drawn from each subject to determine the levels of hemoglobin, protein, triglyceride, cholesterol, etc. The major findings were as follows; First, smokers consumed every food group except fat & oil less frequently than nonsmokers, while they consumed instant food, coffee, alcoholic beverages more frequently than nonsmokers. Dietary habits of smokers such as regularity, balanced diet, skipping meals were worse than those of non-smokers. Second, intakes of energy, fat, carbohydrate, and β-carotene of smokers were lower than those of non-smokers. Third, smokers felt fatigue and other adverse symptoms more often than non-smokers. Fourth, the levels of hemoglobin, albumin and HDL-cholesterol were significantly lower in smokers than non-smokers. Fifth, Smoking history was negatively correlated with food behaviors, energy intake and clinical symptoms. These results suggest that food behaviors, nutrient intakes, hematological findings and clinical symptoms of male high school students were affected by smoking. Therefore, in order to decrease smoking rate of the students, the effect of smoking on nutritional and health status should be informed and nutrition education should be offered to the students.

• Korean Journal of Health Education and Promotion
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• v.18 no.3
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• pp.1-10
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• 2001

The purposes of this study were to identify patients' perceptions toward regulations of smoking in general hospitals and hazards caused by smoking. Moreover this study also identified smoking behaviors and punishment experience due to in-hospital smoking and education experiences of smoking in general hospitals. Around 88.0％ of all respondents regardless of either smokers or non-smokers knew that hospitals are non-smoking area. However, 71.6％ of smokers smoked during their hospital visits. For their smoking, only 51.0％ of smokers utilized smoking rooms or areas for their smoking. Only 55.1％ of smokers experienced punishments or notifications of warning due to their smoking. Around 93.0％ of inpatients and outpatients acknowledged hazards toward their health caused by smoking. However, smokers did not realize the dangerous effects of passive smoking to other persons. Only 38.1％ of smokers said that passive smoking causes hazard of others' health. 63.8％ of smokers hoped for secession of smoking but only 42.8％ of them sustained their non-smoking periods over 5 moths. Based on these results, this study insists that a more enforced smoking policy in general hospitals be desperately needed for protecting patients' health and controlling smoking at unapproved areas. Moreover hospitals should take proactive actions to prevent smoking in hospitals. A health education program in hospitals should promote patients' self-efficacy to stop smoking and patients' understanding of the hazardous effects of passive smoking in hospitals.

• Journal of Community Nutrition
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• v.1 no.2
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• pp.88-97
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• 1999

The purpose of this study was to investigate the nutritional status of serum minerals, ceruloplasmin, and ferroxidase activity in female adolescent students according to their smoking status. The subjects were 87 non-smokers and 88 smokers, who were female high school students. The smokers were divided into tow groups by smoking status, 35 light smokers(pack-year<1) and 53 smokers(pack-year$\geq$1). The serum concentrations of 6 minerals were determined by ICP emission spectroanalyzer. The serum concentration of ceruloplasmin and ceruloplasmin ferroxidase activity were determined. All data were statistically analyzed by SAS PC package program. The serum minerals concentrations of all subjects were in a normal range. There were significantly differences in the concentrations of serum copper, zinc, magnesium, and phosphorus by smoking status while there were no significant differences in the concentrations of serum iron and manganese by smoking status. Furthermore there were no significant differences in the ceruloplasmin concentration and ferroxidase activity by smoking status. In conclusion, smoking status altered the serum levels of some minerals in healthy young women. The minerals levels in light smokers with relatively short pack-year(pack-year<1) were altered compared to those in non-smokers or smokers. This finding seemed to be consistent with the results of previously published data related to antioxidant vitamin and lipid peroxide levels. However further research is needed to clarify these findings in female adolescent smokers.

• The Journal of Korean Medicine
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• v.22 no.4
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• pp.69-78
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• 2001

Objectives : It is known that cigarette smoking is associated with increased risk of both thrombotic and hemorrhagic stroke. However, in Korea, especially in the academic world of Korean Medicine, there is a lack of study about the relation between cigarette smoking and stroke. We carried out a case-control study to clarify the relation between cigarette smoking and stroke. Method : We interviewed 441 stroke patients (236 men, 205 women) as a case group and 432 non-stroke patients (208 men, 224 women) as a control group. We investigated the smoking pattern of all patients and stroke-subtype of the case group. Smoking pattern is classed into two (Class I), four (Class II) and five groups (Class III). Class I consists of current non-smokers and current smokers. Class II consists of non-smokers, former smokers, current light smokers and current heavy smokers. Class III consists of never smoked, secondhand smokers, former smokers, Current light smokers and current heavy smokers. Stroke-subtype consists of cerebral infarction and cerebral hemorrhage. Results : The percentage of current smokers of case group is higher significantly than that of control group. The number of cigarettes smoked per day is associated positively with the risk of stroke. According to our study, generally cigarette smoking is related with ischemic stroke. The percentage of secondhand smokers of the case group is lower than that of the control group. According to our study, characteristically secondhand smoking is associated with hemorrhagic stroke. Conclusions : From the above results we found that cigarette smoking is an important risk factor of stroke - especially cerebral infarction - and the number of cigarettes smoked per day is associated positively with the risk of stroke. Characteristically according to our study, secondhand smoking is associated with hemorrhagic stroke. Overall we conclude that cigarette smoking may be an important preventable factor for stroke.

• Tuberculosis and Respiratory Diseases
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• v.73 no.4
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• pp.210-218
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• 2012

Background: The level of urine cotinine is an indicator of tobacco smoke exposure. The purpose of this study is to investigate urine cotinine for the purpose of assessing the smoking status of Korean smokers and non-smokers exposed to tobacco smoke. Methods: The subjects were identified from the 2007-2009 and the 2010 data sets of the Korea National Health and Nutrition Examination Survey (KNHANES). They were assigned as non-smokers, current smokers and ex-smokers. Non-smokers were also divided into three subset groups according to the duration of smoke exposure. Each group was stratified by gender prior to analysis. Results: The median value of urine cotinine in the male current smokers was 1,221.93 ng/mL which was the highest among all groups. The difference between levels of urine cotinine for male and the female groups was statistically significant (p<0.01). In the female group, passive smoke exposure groups reported higher urine cotinine levels than non-exposure groups (p=0.01). The cutoff point for the discrimination of current smokers from non-smokers was 95.6 ng/mL in males and 96.8 ng/mL in females. The sensitivity and specificity were 95.2% and 97.1%, respectively, in males, 96.1% and 96.5% in females. However, the determination of urine cotinine level was not useful in distinguishing between passive smoke exposure groups and non-exposure groups. Conclusion: Urine cotinine concentration is a useful biomarker for discriminating non-smokers from current smokers. However, careful interpretation is necessary for assessing passive smoke exposure by urine cotinine concentration.

• Korean Journal of Health Education and Promotion
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• v.9 no.1
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• pp.39-47
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• 1992

This study was surveyed among 1136 respondent of high school girls in seoul from Feb. 6, till Feb. 22, 1992 for the purpose of analysing the smoking of high school girls and its factor. The data was analied by X²-test and Multiple Regression and shows the following. 1. Out of 1,136 respondent, the current smokers were found to be 176, 15.5% and the former smokers were 204, 18.0%. This implies that 23.5% of high school girls seoul have experience smoking. 2. For the first smoking time in both smoking group and former smokers, it shows that the third grade of middle school lead the lists. 36.9% (65) of the smokers and 37.3(75)of former smokers experienced the first smoking at that time. 70.5%(124) of the smoking group have the intention to stop smoking and the first reason of it is health problem, 65.6%(75). 3. For the type of the school the smoking rate rages from 2.7%(7) of literary part in day time to 25.3%(97) of vocational part in evening time and the rate of smoking experience shows from 9.9%(26) literary part in day time to 25.3%(97) of vocational part in evening time. This data show that literary part in day time has the lowst rate while vocational part in eveing time the highest rate. 4. Compared with non smoker group, smoking group and former smoking group spent more money (P<0.001) and felt dissatisfied with school life and didn't have good school records. 5. Smoking group and former smokers have more boy friends than non smoking group and in most cases their boy friend have smoking habits (P<0.001) and it is the same with their gril friend (P<0.001). 6. Compared with non smoker group, smoking group and former smokers lack of their parents' interest (P<0.001). But whether it is strict or free there is little difference among the three group. 7. For smoking group and former smoking group, in most cases their parent, brother and sister tend to smoke and especially their sisters' smoking has much influence on their smoking in comparison with non-smokers. 8. Compared with non-smoker group, smoking group and former smoking group tend to think less of the harm of smoking. In regard with health problem, more smoking group and former smokers think that smoking can relieve the stress (P<0.001), and more non-smokers know that when a pregnant woman smokes, it can cause the lack of supply of Oxygen{P<0.01). 9. Smoking group and former smoking group have more positive attitude towards smoking than non-smokers and tend to agree to their boy and girl friends' smoking(P<0.001).

• Journal of the Architectural Institute of Korea Planning & Design
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• v.33 no.12
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• pp.105-112
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• 2017

Through various media, damage of both smoking and second-hand smoking has been recognized, and brought global scale of interest in antismoking. In Korea, government has tightened regulations of smoking in non-smoking zone since December, 1980, and after National Health Promotion Act in 1995, non-smoking zone has been gradually expanded. On the other hand, there were law suits to find those regulation towards smokers are either unconstitutional or not for 4 times. In this current state, people need smoking area to prevent second-hand smoking and to consider smokers in multi-unit dwelling. Main purpose of this research is to plan smoking spaces based on various typology of multi-dwelling plan for protection of both smokers and non-smokers' right. The research group collected and analyzed the smoking behaviors in various multi-unit dwelling types such as flat type, tower type, hybrid type and others. Based on those data, the group found three phenomena. First, there are internal regulations in multi-unit dwelling to make non-smoking zone based on National Health Promotion Act and resident representative meeting decision. Second, main smoking activities are occurring at major traffic line and entrances. Third, smoking inside of multi-unit dwelling complex causes second-hand smoking to residents live in $1^{st}$ floor and when they enter. Therefore, one can achieve both smokers' and non-smokers' protection of right by creating a designated smoking space near main entrances of multi-unit dwelling complex to consider smokers' and prevents second-hand smoking by using shaft space, which is in core space, to ventilate tobacco smoke through roof.

• Korean Journal of Biological Psychiatry
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• v.27 no.2
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• pp.101-111
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• 2020

Objectives The aim of this study is to investigate the association between secondhand smoke (SHS) exposure and depressive symptoms among Korean adults. This study also explored the mediating role of self-rated health (SRH) and perceived usual stress (PUS) in the association between depressive symptoms, suicidal ideation and SHS exposure. Methods Data from the Korea National Health and Nutrition Examination Surveys (KNHANES) in 2014 and 2016 was analyzed for 10539 participants aged 19 years or older. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated in the logistic regression analysis with adjustment for the potential confounding factors. We also adopted the mediation analysis method by Hayes and Preacher. Results After adjusting for the potential confounding factors, SHS at home and at public places were associated with depressive symptoms and suicidal ideation among non-smokers. After adjusting for the potential confounding factors, SHS at home and at public places was associated with depressive symptoms and suicidal ideation among non-smokers. Meanwhile SHS at workplaces was associated with depressive symptoms among former smokers and with suicidal ideation among current smokers. There was an additive effect of SHS on depressive symptoms only among non-smokers. SRH mediated the association between SHS and depressive symptoms and suicidal ideation among non-smokers. We did not observe any significant mediating effect of SRH nor PUS on the association between SHS and depressive symptoms among former and current smokers. Conclusions SHS may be associated with depressive symptoms and suicidal ideation in Korean adults. Our study elucidated how SHS interacted with depressive symptoms among non-smokers through the mediation by SRH.