• 인간식물환경학회지
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• 제21권6호
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• pp.557-564
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• 2018

Along with the aging society, the prevalence of dementia is also increasing. Dementia causes short-term memory loss as well as difficulties of performing daily activities and gradually causes suffering of the patients and their family. In spite of various programs for prevention of dementia of older people are being implemented, there is a lack of developing natural-based program for physical and mental health promotion. Therefore, it is necessary to develop programs for the elderly living alone who are more vulnerable to dementia because of their social and economic isolation. The purpose of this study was to develop a natural-based program and investigate the effects of 10 weeks forest therapy program for dementia prevention to improve the psychological and physical health of the elderly living alone. The experimental subjects were 30 elderly (aged 65 or older) and 31 elderly participated in control group. The Stress response, depressive symptoms, weight, body mass index (BMI), fat mass and muscle mass were measured for pre and post test. The results showed that the experimental group showed subjective stress relief (t=5.249, p=.000), improvement in symptoms of depression (t=4.152, p=.000), and decreases in weight (t=2.686, p=.012), BMI (t=2.629, p=.014) and fat mass (t=2.918, p=.007) after the forest therapy program. The experimental group showed lower stress reactions(t=-7.185, p=.000) and less depressive symptoms (t=-5.303, p=.000) than control group after participating the program. These results suggest that periodic forest exposure can help having less stressful and depressive status than non-forest exposure and the forest therapy program can reduce participants' psychological and physical risk factors of dementia.

• Smart Structures and Systems
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• 제24권1호
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• pp.127-139
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• 2019

Residual drifts after an earthquake can incur huge repair costs and might need to replace the infrastructure because of its non-reparability. Proper functioning of bridges is also essential in the aftermath of an earthquake. In order to mitigate pounding and unseating damage of bridges subjected to earthquakes, a self-adaptive Ni-Ti shape memory alloy (SMA)-cable-based frictional sliding bearing (SMAFSB) is proposed considering self-adaptive centering, high energy dissipation, better fatigue, and corrosion resistance from SMA-cable component. The developed novel bearing is associated with the properties of modularity, replaceability, and earthquake isolation capacity, which could reduce the repair time and increase the resilience of highway bridges. To evaluate the super-elasticity of the SMA-cable, pseudo-static tests and numerical simulation on the SMA-cable specimens with a diameter of 7 mm are conducted and one dimensional (1D) constitutive hysteretic model of the SMAFSB is developed considering the effects of gap, self-centering, and high energy dissipation. Two types of the SMAFSB (i.e., movable and fixed SMAFSBs) are applied to a two-span continuous reinforced concrete (RC) bridge. The seismic vulnerabilities of the RC bridge, utilizing movable SMAFSB with the constant gap size of 60 mm and the fixed SMAFSBs with different gap sizes (e.g., 0, 30, and 60 mm), are assessed at component and system levels, respectively. It can be observed that the fixed SMAFSB with a gap of 30 mm gained the most retrofitting effect among the three cases.

• Natural Product Sciences
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• 제25권3호
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• pp.208-214
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• 2019

Trigonella foenum-graceum L. (fenugreek) is a phytoestrogen, a nonsteroidal organic chemical compound from plants which has similar mechanism of action to sex hormone estradiol-$17{\beta}$. This study aims to assess the effectivity of fenugreek seeds extract on collagen type I alpha 1 (COL1A1) and collagen type III alpha 1 (COL3A1) which are both decreased in aging skin and become worsen after menopause. This in vitro experimental study used old human dermal fibroblast from leftover tissue of blepharoplasty on a postmenopausal woman (old HDF). As a control of the fenugreek's ability to trigger collagen production, we used fibroblast from preputium (young HDF). Subsequent to fibroblast isolation and culture, toxicity test was conducted on both old and young HDF by measuring cell viability on fenugreek extract with the concentration of 5 mg/mL to $1.2{\mu}g/mL$ which will be tested on both HDF to examine COL1A1 and COL3A1 using ELISA, compared to no treatment and 5 nM estradiol. Old HDF showed a 4 times slower proliferation compared to young HDF (p<0.05). Toxicity test revealed fenugreek concentration of $0.5-2{\mu}g/mL$ was non-toxic to both old and young HDF. The most significant fenugreek concentration to increase COL1A1 and COL3A1 secretion was $2{\mu}g/mL$ (p<0.05).

• 대한토목학회논문집
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• 제39권3호
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• pp.441-449
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• 2019

최근 국내에서 경주지진(2016.09)과 포항지진(2017.11) 등 규모 5.0 이상의 지진이 발생하여 구조물의 내진안전성에 대한 관심이 증가하고 있다. 특히, 인명피해나 재산손실을 유발하는 생활시설물은 더욱 중요성이 강조되고 있다. 생활시설물 중 가스와 유류 등의 저장시설물이 있으며 물을 저장하는 탱크가 대표적이다. 본 연구에서는 액체저장탱크의 내진성능향상을 위해 면진의 일종인 납고무받침(Lead Rubber Bearing)을 적용하고자 한다. 액체저장탱크의 기초를 고려하여 납고무받침을 설계하였으며, 실험체를 제작하여 압축 및 전단특성실험을 통해 납고무받침의 일반적 물성을 확인하였다. 납고무받침에 대한 내구성 실험 이후 진동대 실험 및 ANSYS를 이용한 유한요소해석을 통해 비면진 및 면진 적용에 따른 액체저장탱크의 거동을 분석하였다.

• Natural Product Sciences
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• 제28권3호
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• pp.143-152
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• 2022

In our study, sixteen known phenolic compounds, including quercetin (1), methyl gallate (2), caesalpiniaphenol C (3), 8S,8'S,7'R-(-)-lyoniresinol (4), 7,3',5'-trihydroxyflavanone (5), sappanchalcone (6), sappanone A (7), taxifolin (8), fisetin (9), fustin (10), (+)-catechin (11), brazilin (12), 3,4,5-trimethoxyphenyl β-ᴅ-glucopyranoside (13), 1-(2-methylbutyryl)phloroglucinol-glucopyranoside (14), (+)-epi-catechin (15), and astragalin (16) and one mixture of two conformers of protosappanin B (17/18) were isolated from the stems of Caesalpinia decapetala var. japonica. Their structures were elucidated based on a comparison of their physicochemical and spectral data with those of literature. To the best of our knowledge, this represents the first isolation of compounds 3, 4, 8, 9, and 10 from C. decapetala and compounds 13 and 14 from the Caesalpinia genus. All the isolated compounds were evaluated for their inhibitory effect against the α-glucosidase enzyme. Among them, two flavonols (1 and 9), one chalcone (6), and one homoisoflavanone (7) exhibited an inhibitory effect on α-glucosidase action with an IC₅₀ range value of 5.08-15.01 μM, stronger than that of the positive control (acarbose, IC₅₀ = 152.22 μM). Kinetic analysis revealed that compounds 1 and 9 showed non-competitive α-glucosidase inhibition, while the inhibition type was mixed for compounds 6 and 7.

• 스마트미디어저널
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• 제12권3호
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• pp.9-18
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• 2023

코로나19의 심화로 인해 고강도 사회적 거리두기가 장기화되고 많은 사회적 문제를 나았다. 특히 비대면 체계로 인해 물리적, 심리적 고립이 발생하였고 많은 피해가 발생하였다. 코로나로 인한 여러 사회적 문제들은 코로나19로 피해를 입은 모든 사람들에게 심한 스트레스로 작용하여 결국엔 우울증 등의 정신건강을 위협하는 요소로 작용되었다. 정신질환을 겪는 사람들은 늘어나는 반면 실제로 정신건강 서비스 이용률은 저조한 상황이기 때문에 정신건강 문제를 겪고 있는 사람들을 위한 시스템 구축이 필요한 상황이다. 이에 본 연구에서는 우울증 대상자와 일반인 대상자로부터 스마트폰을 이용한 센서 정보를 바탕으로 우울증 탐지 및 위급상황 탐지모델을 구축하였다. 우울증 탐지와 위급상황 탐지를 위해 VAE, DAGMM, ECOD, COPOD, LGBM 알고리즘을 이용하였다. 연구 결과로 우울증 탐지 모델은 F1 score 0.93, 위급상황 탐지 모델은 F1 score 0.99의 성능의 모델을 구축하였다.

• 한국정책학회보
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• 제21권1호
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• pp.337-361
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• 2012

본 연구는 노인의 사회적 고립과 외로움을 치유할 수 있는 세대 간 가족관계를 국가가 적극적 노년정책 수단을 통해 개선을 유도하는 것이 가능하다는 실증적 증거를 제공하기 위해 수행되었다. 이를 위한 실증분석의 핵심과제는 역방향의 인과관계의 존재에 의한 선택편의를 통제하는 작업이며 이를 위하여 '적격비참여자'로 비교집단을 구성하여 도구변수로 실증모형을 추정하는 전략을 채택하였다. 분석결과 노년기의 생활패턴이 적극적으로 변화함에 따라 자녀들과의 가족관계는 경제적 연대측면이나 유대적 연대측면 모두에서 유의미하게 개선되는 것으로 나타났다. 또한 이러한 개선효과는 자녀세대와 동거하지 않는 노인부모들에게 집중되어 발생하는 것으로 나타났다. 본 연구의 결과는 세대 간 가족관계의 개선이 적극적 노년정책의 새로운 편익으로 추가될 수 있는 실증적 근거를 제시하였다는데 정책적 의미를 갖는다.

• Journal of Preventive Medicine and Public Health
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• 제56권1호
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• pp.31-40
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• 2023

Objectives: This study investigated the effect of cognitive impairment on the association between social network properties and mortality among older Korean adults. Methods: This study used data from the Korean Social Life, Health, and Aging Project. It obtained 814 older adults' complete network maps across an entire village in 2011-2012. Participants' deaths until December 31, 2020 were confirmed by cause-of-death statistics. A Cox proportional hazards model was used to assess the risks of poor social network properties (low degree centrality, perceived loneliness, social non-participation, group-level segregation, and lack of support) on mortality according to cognitive impairment. Results: In total, 675 participants (5510.4 person-years) were analyzed, excluding those with missing data and those whose deaths could not be verified. Along with cognitive impairment, all social network properties except loneliness were independently associated with mortality. When stratified by cognitive function, some variables indicating poor social relations had higher risks among older adults with cognitive impairment, with adjusted hazard ratios (HRs) of 2.12 (95% confidence interval [CI], 1.34 to 3.35) for social nonparticipation, 1.58 (95% CI, 0.94 to 2.65) for group-level segregation, and 3.44 (95% CI, 1.55 to 7.60) for lack of support. On the contrary, these effects were not observed among those with normal cognition, with adjusted HRs of 0.73 (95% CI, 0.31 to 1.71), 0.96 (95% CI, 0.42 to 2.21), and 0.95 (95% CI, 0.23 to 3.96), respectively. Conclusions: The effect of social network properties was more critical among the elderly with cognitive impairment. Older adults with poor cognitive function are particularly encouraged to participate in social activities to reduce the risk of mortality.

• 대한간호학회지
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• 제53권1호
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• pp.87-100
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• 2023

Purpose: This study aimed to develop a nursing simulation learning module for coronavirus disease 2019 (COVID-19) patient-care and examine its effects on clinical reasoning competence, clinical competence, performance confidence, and anxiety in COVID-19 patient care for nursing students. Methods: A non-equivalent control group pre- and post-test design was employed. The study participants included 47 nursing students (23 in the experimental group and 24 in the control group) from G City. A simulation learning module for COVID-19 patient-care was developed based on the Jeffries simulation model. The module consisted of a briefing, simulation practice, and debriefing. The effects of the simulation module were measured using clinical reasoning competence, clinical competence, performance confidence, and anxiety in COVID-19 patient-care. Data were analyzed using χ²-test, Fisher's exact test, t-test, Wilcoxon signed-rank test, and Mann-Whitney U test. Results: The levels of clinical reasoning competence, clinical competence, and performance confidence of the experimental group were significantly higher than that of the control group, and the level of anxiety was significantly low after simulation learning. Conclusion: The nursing simulation learning module for COVID-19 patient-care is more effective than the traditional method in terms of improving students' clinical reasoning competence, clinical competence, and performance confidence, and reducing their anxiety. The module is expected to be useful for educational and clinical environments as an effective teaching and learning strategy to empower nursing competency and contribute to nursing education and clinical changes.

• 한국미생물·생명공학회지
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• 제51권2호
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• pp.203-207
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• 2023

옥수수 근권 토양으로부터의 N₂O 환원 근권세균인 Pseudomonas sp. M23을 분리하였다. M23 균주의 최대 N₂O 환원속도는 15.6 mmol·g-dry cell^-1·h^-1이었다. M23 균주의 N₂O 환원 활성은 디젤 오염물에 의해 저해받지 않았고, 옥수수와 톨페스큐 뿌리삼출물 첨가에 의해 향상되었다. M23 균주 접종은 옥수수와 톨페스큐를 이용한 디젤 오염 토양의 정화 효율을 저해하지 않았다. M23 균주를 접종한 토양에서 재배한 식물체의 뿌리무게는 미접종 토양에서의 뿌리무게보다 컸으나, 유의적 차이는 없었다. 이러한 결과는 Pseudomonas sp. M23이 유류 오염 토양의 근권정화 과정에서 N₂O 배출을 저감하는데 활용 가능한 유용한 세균임을 시사한다.