• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.272-272
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• 2000

since the controller is part or the overall closed-Loop system, it is necessary that the designed controller be able to tolerate some uncertainty in its coefficients. The adequate stability and performance margins are required for the designed nominal controllers. In the paper. we study the method to design the non-fragile fixed-structured controller for real parametric uncertain systems. When we impose the controller parameter perturbation, the structure of the controller must be given. Therefore, we assume that the controller has fixed-structure. The fixed-structure controller is practically necessary especially when the robust controller synthesis results in a high-order controller. In SISO systems, we propose the robust controller design method using the Mapping theorem. In the method, the plant uncertainty and controller Parameter are of the multilineal form in the stability and performance conditions. Then, the controller synthesis problem is easily recast to Linear Programming Problem.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.45 no.3
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• pp.32-41
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• 2008

In this paper, we describe the synthesis of robust and non-fragile $H^{\infty}$ state feedback controllers for linear systems with affine parameter uncertain tracking servo system of blu-ray disc drive, as well as static state feedback controller with polytopic uncertainty Similarity any other control system, the objective of the track-following system design for optical disc drives is to construct the system with better performance and robustness against modeling uncertainties and various disturbances. Also, the obtained condition can be rewritten as parameterized linear matrix inequalities(PLMIs), that is, LMIs whose coefficients are functions of a parameter confined to a compact set. We show that the resulting controller guarantees the asymptotic stability and disturbance attenuation of the closed loop system in spite of controller gain variations within a resulted polytopic region.

• Clinical and Experimental Pediatrics
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• v.46 no.12
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• pp.1186-1193
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• 2003

Purpose : Fragile sites are points on chromosomes which tend to break non-randomly when exposed to specific chemical agents or conditions of tissue culture. The chromosomal break induced by the antineoplastic drug, 1-${\beta}$-D-arabinofuranosyl-cytosine(Ara-c), was investigated to study the laboratory conditions in which the incidence of chromosomal break could be enhanced. Besides, the fragile sites induced by Ara-C were investigated and compared to the already known locations of the specific chromosomal alterations observed in specific neoplasms. Methods : T-lymphocytes from theree normal males and three females were cultured for 48 hours. Cells from each individual were exposed to the Ara-C for an additional 24 hours. After the caffeine was added during the last six hours culture, the metaphase chromosomes were prepared following the conventional method. A site was considered fragile if it was found to break two or more per 100 chromosomal breaks in more than four of six individuals tested. Results : Ara-C induced 252.1 chromosomal breaks per 100 mitotic cells and this result was significantly higher than that of the control, which induced 25.2 breaks(P<0.05). The incidence of the chromosomal break by Ara-C was higher, if cultured in the MEM-FA, which has no folic acid, than in the RPMI 1640 which contains enough folic acid(P<0.05). The most common break site by Ara-C was 3p14.2(FRA3B). There were 20 fragile sites induced by Ara-C. Among these 20 fragile sites, seven coincided with the locations of the mapped oncogenes, JUN, SKI, REL, N-MYC, FHIT, MET, ETS-1, and FOS. Conclusion : S phase specific chemotherapeutic agent, Ara-C, induced the expression of the chromosomal fragile sites effectively using the T-lymphocyte in vitro. Some of the fragile sites by Ara-C highly coincided with the oncogenes and neoplasm specific chromosome breakpoints. In this regard, the fragile sites reported here could provide the unknown neoplasm related chromosomal alternation points.

• KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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• v.4B no.3
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• pp.108-113
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• 2004

This paper presents methods to improve performance of the power supply system in a NASA deep space explorer. In the Stirling engine driven reciprocating Brushless DC (BLDC) generator, the accurate position information of the prime mover is important to diagnose the performance of the engine and prevent distortion of the output power. Since sensors to detect the position are fragile and unreliable, and conventional sensorless techniques have drawbacks in the low speed region, a novel sensorless position detection technique for the prime mover has been proposed and verified. Another major issue of the generator for the spacecraft is power density maximization. The mass of the power system is important to the mass of the satellite. Therefore, the components of the spacecraft should be lightweight. Conventional rectification methods cannot achieve the maximum power possible due to non-optimal current waveforms. The optimal current waveform for maximizing power density and minimizing machine size and weight in a nonsinusoidal power supply system has been derived, incorporated in a control system, and verified by simulation work.

• Proceedings of the Korea Society of Environmental Biology Conference
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• 2003.11a
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• pp.12-15
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• 2003

The effects of the non-steroidal ecdysteroid agonist tebufenozide on larvae of C. faviplumus and C. riparius were tested in the laboratory. In the most treatments it reached a statistically significant difference from the control condition. As the concentration of tebufenozide was increased, a relatively larger proportion of the observed mortality was associated with the metamorphosis and molting process. Also, the larval mortality of the first larvae was higher than the fourth-instar larvae in C. riparius. In terms of development, the effects of tebufenozide were delayed growth stage in relatively lower concentration such as 10 $\mu\textrm{g}$/L treatments. Based on the mortality, the susceptibility followed the first-instar C. riparius > the fourth-instar C. flaviplumus > the fourth-instal C. riparius. The morphological effects showed that the first and second segments of body of exposed larvae with tebufenozide expanded slowly and not made a complete cephalothorax of pupae during long times or days. And the head capsule slipped down and forward, revealing a fragile and non-pigmented, unsclerotized new head capsule. There was obvious significant difference in the male/female ratio in contaminated fourth larvae of C. riparius. Also, due to the different emergence periods of male/female in low insecticide concentrations, mating chances or opportunities of insects should be decreased. Accordingly, ecological strategies for keeping of sustainable populations should be disrupted.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.165-171
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• 2013

The aim of the present study was to analyze the expression of FHIT and WWOX in nasopharyngeal carcinoma (NPC) and correlations with clinical pathologic features. mRNA expression of the FHIT and WWOX was assessed by real-time fluorescent relatively quantitative PCR in 61 NPC tissues and 45 non-cancerous nasopharyngeal tissues. As a result, mRNA expression levels of both FHIT and WWOX were significantly lower in NPC patients than in control samples (P=0.049 and 0.045, respectively). Moreover, the mRNA expression of both had an inverse relation with larger invasive range (P=0.035 and 0.048, respectively), poor histologic differentiation (P=0.012 and 0.016) and advanced clinical stage (P=0.026 and 0.038). Consistency was found between expression of FHIT and WWOX in the same NPC tissues (r=0.681, P=0.00). In conclusion, synergy between FHIT and WWOX may exist in the development of NPC so that the two factors may be considered as important genetic markers. Detecting the expression of FHIT and WWOX should provide clinically significant information relevatn to tumor diagnosis, progression and treatment modalities for NPC.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.47 no.6
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• pp.64-72
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• 2010

In general, due to the interactions among subsystems, it is difficult to design an decentralized controller for nonlinear interconnected systems. In this study, the model of nonlinear interconnected systems is studied via decentralized fuzzy control method with time delay and polytopic uncertainty. First, the nonlinear interconnected system is represented by an equivalent Takagi-Sugeno type fuzzy model. And the represented model can be rewritten as Parameterized Linear Matrix Inequalities(PLMIs), that is, LMIs whose coefficients are functions of a parameter confined to a compact set. We show that the resulting fuzzy controller guarantees the asymptotic stability and disturbance attenuation of the closed-loop system in spite of controller gain variations within a resulted polytopic region by example and simulations.