• Journal of Korean Ophthalmic Optics Society
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• v.13 no.1
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• pp.107-112
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• 2008

urpose: This thesis is a study the Night myopia was surveyed by Subjective refraction and Objective refraction (Dark retinoscopy), and analyzed the relationship between them. It also looked at the relation between Night myopia and pupil size. Methods: 82 adult subjects (ages of 19 to 44, 44 males and 38 females) were examined by Subjective refraction and Objective refraction in the light place. Then Night myopia and pupil size were examined by Subjective refraction and Objective refraction in the dark again. The Statistics were analyzed by SPSS (Statistical Package for Social Science). Results: As the subjects became younger, the observed Night myopia was getting higher in both Subjective refraction, $x^2$=219.48 (p<0.01) and Objective refraction, $x^2$=241.98 (p<0.01). The relationship was statistically significant by showing large pupil size, $x^2$=151.74 (p<0.01). In Objective refraction, as pupil size became larger in the dark place, so did Night myopia, $x^2$=84.27 (p<0.01), reaching a statistically significant correlation, however, the correlation was low in Subjective refraction. In Subjective refraction, observed Night myopia was 73%, 64 examples of 88 examples, a standard of 0.96${\pm}$0.4584D in ${\pm}$0.25D, in male examples, and it was 64%, 49 examples of 76 examples, a standard of 1.01${\pm}$0.4509D in ${\pm}$0.25D, in female examples. In Objective refraction, it was 48%, 42 examples of 88 examples, in standard of 0.85${\pm}$0.4651D in ${\pm}$0.25D, in male examples. And it was 71%, 54 examples of 76 examples, in standard of 0.96${\pm}$0.4133D in ${\pm}$0.25D, in female examples. Conclusions: Night myopia which is measured by both methods, observed as $x^2$=265.35 (p<0.01) and showed a large relationship. The correlation between the two refractions suggests that observed night myopia diopter by Subjective refraction could be used as correction of night myopia.

• Proceedings of the Korean Society of Food Science and Nutrition Conference
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• 2001.12a
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• pp.52-60
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• 2001

Purpose: We performed a randomized, double-blind, placebo-controlled trial in mild to moderate myopia patients to evaluate the benefit of taking a nutrient supplement containing anthocyanoside oligomers for improving nocturnal visiual function and/or clinical symptoms. Methods: The subjects included have refractive error between -lD(Diopters) $\~$-8D in both eyes, symptoms of decreased night vision and asthenopia based on the scoring result of a pre-structured questionnaire, and abnormal results of mesopic contrast sensitivity(MCS) screening test showing abnormal curve of contrast sensitivity in the middle and high frequency level, between 6.0 and 30.0 CPD(Cycles per degree) at mesopic condition(-2$\~$0 log cd/$m^2$). Total 60 people who qualified the criteria above were enrolled and the subjects were instructed to take the investigational product (anthocyanoside or placebo) twice daily for a 4 week period. The enrolled subjects were investigated for nocturnal vision performance by MCS and clinical symptoms at their first visit and re-evaluated at post-intervention (4 weeks later). MCS was measured and improvement of contrast threshold level according to each CPD was calculated by subtracting initial values from final values. Age, refractive error, and MCS were compared between the placebo and anthocyanoside. Results: After 4 weeks of drug administration 22 of the anthocyanoside group showed symptom improvement compared to 1 of the placebo group (p=0.000). Contrast sensitivity levels according to each CPD before and after drug treatment showed significant improvement in the anthocyanoside group but not in the placebo group. Mean MCS change of anthocyanoside group is 2.41$\pm$1.91 which showed significant improvement compared to -0.40$\pm$2.47 of the placebo group(p=0.000). MCS changes of anthocyanoside group showed significant improvement compared to placebo group in all levels of CPD(p<0.05). During our investigation none of the subjects complained of specific side effects related to anthocyanoside use. Conclusion: Our results show that under careful selection of people with significant symptoms and definite MCS abnormalities, anthocyanoside oligomers may improve the subjective symptoms and objective MCS results.