• The Korean Journal of Ecology
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• 제2권1호
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• pp.1-8
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• 1978

Epiphytic lichens were sampled quantitatively on the cherry trees (Prunus serrulata) at Jeonju and Hadong along both north and south exposures of tat trees. Coverage of lichens was determinated for each species by 10*20cm quadrat. Lichen species diversities such as total diversity (D), mean diversity (D), Shannon diversity (D') and redundancy (R) were estimated according to Brillouin and Shannon equation. The importance value of lichen species was meassured by niche preemption model, The importance value transformed into some fraction k of the niche space. The value of k was compared with aggregation of lichens communities in to areas. The ten most important awariensis, Parmelia incurva, Parmelia crinita, Dirinaria applanta, Parmelia wallichiana, Parmelia austrosinensis and Cetraria platyphylla. The mean coverage epiphytic lichens on north side of tree was higher than of south side in two areas. The species diversities of epiphytic lichen of two areas shows that a change in the value of D' along vertical was not paralled with the D and R. In Kumsan-sa, D, D and D' increased upward along the tree of north exposure, but did not follow this trend in south, However in Sangge-sa, D, D and D' of both sides increased.

• Journal of Plant Biology
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• 제27권1호
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• pp.25-32
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• 1984

A study on the dominance-diversity of forest vegetation in Mt. Seolag was conducted from May 1981 to Aug. 1983. Based on the field data, the dominance-diversity curves were for 16 sites including slopes and vallies. The curves are grouped in two types, lognormal distribution at the sites of mature vegetation and geometric series at the disturbed or rocky sites. It seems that the curves express the nature of their ecocline, by the hypotheses of some investigators, i.e. Random Niche hypothesis, Niche Pre-emption hypothesis, Lognormal distribution and Logarithmic series. The dominance concentration among the southern, northern and western slope, H'=1.282 at southern slope and H'=1.385 at western slope. Dominance-diversity curves of 16 sites showed Preston's lognormal distribution with small variations among them. It seems that the dominance diversity reflects the differences in the coenocline of their sites. The top 10 dominant species in species sequence of 113 tree species in whole the mountain, were noticed: Quercus mongolica, Pinus densiflora, Acer pseudo-siebold anum, Quercus serrata, Carpinus laxiflora, Styrax obassia, Fraxinus rhynchophylla, Tilia amurensis, Lindera obtusiloba and Abies holophylla in order.

• 한국발생생물학회지:발생과생식
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• 제25권4호
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• pp.313-319
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• 2021

Hub cells comprise a niche for germline stem cells and cyst stem cells in the Drosophila testis. Hub cells arise from common somatic gonadal precursors in embryos, but the mechanism of their specification is still poorly understood. Here we find that RNA binding proteins Lin28 and Imp mediate transcript stability of Bowl, a known hub specification factor; Bowl transcripts were reduced in the testis of Lin28 and Imp mutants, and also when RNA-mediated interference against Lin28 or Imp was expressed in hub cells. In tissue culture Luciferase assays involving the Bowl 3'UTR, stability of Luc reporter transcripts depended on the Bowl 3'UTR and required Lin28 and Imp. Our findings suggest that proper Bowl function during hub cell specification requires Lin28 and Imp in the testis hub cells.

• International Journal of Stem Cells
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• 제16권3호
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• pp.251-259
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• 2023

Mesenchymal stromal cells (MSCs) have attracted scientific and medical interest due to their self-renewing properties, pluripotency, and paracrine function. However, one of the main limitations to the clinical application of MSCs is their loss of efficacy after transplantation in vivo. Various bioengineering technologies to provide stem cell niche-like conditions have the potential to overcome this limitation. Here, focusing on the stem cell niche microenvironment, studies to maximize the immunomodulatory potential of MSCs by controlling biomechanical stimuli, including shear stress, hydrostatic pressure, stretch, and biophysical cues, such as extracellular matrix mimetic substrates, are discussed. The application of biomechanical forces or biophysical cues to the stem cell microenvironment will be beneficial for enhancing the immunomodulatory function of MSCs during cultivation and overcoming the current limitations of MSC therapy.

• International Journal of Stem Cells
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• 제15권1호
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• pp.60-69
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• 2022

Organoids show great potential in clinical translational research owing to their intriguing properties to represent a near physiological model for native tissues. However, the dependency of organoid generation on the use of poorly defined matrices has hampered their clinical application. Current organoid culture systems mostly reply on biochemical signals provided by medium compositions and cell-cell interactions to control growth. Recent studies have highlighted the importance of the extracellular matrix (ECM) composition, cell-ECM interactions, and mechanical signals for organoid expansion and differentiation. Thus, several hydrogel systems prepared using natural or synthetic-based materials have been designed to recreate the stem cell niche in vitro, providing biochemical, biophysical, and mechanical signals. In this review, we discuss how recapitulating multiple aspects of the tissue-specific environment through designing and applying matrices could contribute to accelerating the translation of organoid technology from the laboratory to therapeutic and pharmaceutical applications.

• BMB Reports
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• 제57권8호
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• pp.352-362
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• 2024

Hematopoietic stem cell transplantation (HSCT) remains an indispensable therapeutic strategy for various hematological diseases. This review discusses the pivotal role of bone marrow (BM) niches in influencing the efficacy of HSCT and evaluates the current animal models, emphasizing their limitations and the need for alternative models. Traditional animal models, mainly murine xenograft, have provided significant insights, but due to species-specific differences, are often constrained from accurately mimicking human physiological responses. These limitations highlight the importance of developing alternative models that can more realistically replicate human hematopoiesis. Emerging models that include BM organoids and BM-on-a-chip microfluidic systems promise enhanced understanding of HSCT dynamics. These models aim to provide more accurate simulations of the human BM microenvironment, potentially leading to improved preclinical assessments and therapeutic outcomes. This review highlights the complexities of the BM niche, discusses the limitations of current models, and suggests directions for future research using advanced model systems.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2003년도 somma/kms meeting
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• pp.211-211
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• 2003

• 한국동물학회:학술대회논문집
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• 한국동물학회 1996년도 한국생물과학협회 국제학술대회
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• pp.114.2-114
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• 1996

No Abstract, See Full Text

• 한국환경보건학회지
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• 제31권3호
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• pp.199-206
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• 2005

C. neoformans-associated cryptococcosis is primarily a disease of immunocompromised persons, has a world-wide distribution, and is often spread by pigeons in the urban environment. In contrast, C. gattii causes infection in normal hosts, has only been described in tropical and semi-tropical areas of the world, and has a unique niche in river gum Eucalyptus trees. Cryptococcosis is acquired through inhalation of the yeast propagules from the environment. C. gattii has been identified as the cause of an emerging infectious disease centered on Vancouver Island, British Columbia, Canada. No cases of C. gattii-disease were diagnosed prior to 1999; the current incidence rate is 36 cases per million population. A search was initiated in 2001 to find the ecological niche of this basidiomycetous yeast. C. gattii was found in the environment in treed areas of Vancouver Island. The highest percentage of colonized-tree clusters were found around central Vancouver Island, with decreasing rates of colonization to the north and south. Climate, soil and vegetation cover of this area, called the Coastal Douglas fir biogeoclimatic zone, is unique to British Columbia and Canada. The concentration of airborne C. gattii was highest in the dry summer months, and lowest during late fall, winter, and early spring, months which have heavy rainfall. The study of the emerging colonization of this organism and subsequent cases of environmentally acquired disease will be informative in planning public health management of new routes of exposure to exotic agents in areas impacted by changing climate and land use patterns.

• Strategy21
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• 통권42호
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• pp.224-257
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• 2017

As the Trump administration withdraws the Paris Climate Agreement and shows its antipathy toward free trade, the U.S.'s soft power is most likely to weaken and its behaviors could be perceived as acts to surrender the U.S. hegemonic leadership in the world stage. Hegemonic stability theory notes that the existence of a hegemonic power contributes to international stability in the sense that it provides international public goods. A lack of the U.S's leadership in international politics, however, could be recognized as its denial of a hegemonic status. Is it intentional or accidental? The U.S's denial of hegemonic roles is the byproduct of the Trump administration's "American First" policy, not the showcase of its intention to transit hegemony to others. What is noteworthy is that China targets a niche market of hegemony as the U.S. denies its roles as the international leader. Put it another way, China attempts to ride hegemony for free when the U.S. denies its hegemonic roles accidentally. Faced with a niche market of hegemony, China has begun to accelerate its national strategy to make "Chinese Dream" come true. To that end, China promised again to keep the Paris Climate Agreement and attempts to play more active its roles in Shanghai Cooperation Organization(SCO), Asia Infra Investment Bank(AIIB), and "One Belt, One Road". Despite all these efforts, the U.S. is most likely to withdraw its denial of hegemony any time soon. The U.S's resumption of Freedom of Navigation Operations(FONOPs) could be a precursor of the return to a hegemonic power's willingness. In this vein, it is noteworthy that the South China Sea serves as a quasi-war zone for hegemonic conflict.