• 한국의류학회지
• /
• 제27권3_4호
• /
• pp.333-342
• /
• 2003

The purpose of the study is to understand the newer and more direct design techniques, and to provide information to exert creativity in designing. The headdress, one of dress items, was selected so that the change might be investigated in designs and production methods. A headdress was manufactured on the basis of literature review and portrait analysis. The target period of the study was limited to Henry Ⅶ and Henry Ⅷl(1485∼l547) when gable headdress was put on. The details and the patterns of gable headdress were identified for the selected gable hood to be manufactured. It was not possible to get the same dress material, so a similar one was made as in the pictures. The same was done to the color. Putting the focus of the study on the reproduction of the figure in the portrait, some dimension were measured in bodily proportion and patterns were made by three-dimensional cutting. As results, some dimensions used in the manufacture had some limits.

• 대한방사선기술학회지:방사선기술과학
• /
• 제4권1호
• /
• pp.23-30
• /
• 1981

In chest x-ray radiography, intensifying screen is used to the exposed dose of patients. Recently, newer materials-rere earth elements-are used in intensifying screen. Authors studied the aspects of chest x-ray radiogram and obtained the results that rare earth element intensifying screen did not harm in detail and could reduce the exposed dose of patient by 1/24 and below.

• Pediatric Infection and Vaccine
• /
• 제16권1호
• /
• pp.6-12
• /
• 2009

There are relatively few novel antimicrobial agents despite the dramatic increase in antimicrobial resistance and multiple drug resistance of clinical isolates worldwide. Vancomycin is still the most widely used antibiotic for treating resistant Gram-positive coccal infections in children, especially for methicillin-resistant Staphylococcus aureus. For children with Gram-positive coccal infections where vancomycin is not effective or older therapeutic agents cannot be tolerated, linezolid, quinupristin-dalfopristin or daptomycin may be useful in the appropriate clinical setting. For Gram-negative bacterial infections, new carbapenems await clinical application. Tebipenem pivoxil is a novel oral carbapenem undergoing clinical trials for acute otitis media in pediatric patients. Antiviral drug development is now progressing at the pace of antibiotic development 30 years ago. Newer antiviral agents used for the treatment of herpes viruses and hepatitis C virus infections in children are included in this review.

• Asia pacific journal of information systems
• /
• 제25권1호
• /
• pp.61-81
• /
• 2015

Investment in research and development (R&D) is critical in the information technology (IT) firms, where newer and better technology is a quintessential goal that directly affects innovation and competitive advantage. This study investigates how R&D investment influences firm performance and value, and how the effect of R&D investment differs between IT hardware and software firms. We also analyze the relationship between firm age and R&D investment in order to identify learning effects on continuous R&D investment. The empirical investigation in this study, based on longitudinal archival data from 2001 to 2010, found a significant effect of R&D investment on firm performance in IT firms. Further, this study demonstrates causal relationship between firm age, and verifies that learning effects are present in R&D investment. Moreover, the results are found to differ between IT hardware and IT software firms.

• International Journal of Reliability and Applications
• /
• 제2권2호
• /
• pp.81-97
• /
• 2001

Lifetesting problems have been the subject of investigations for over three decades. Most suggested approaches are markedly different from those used in the related but wider goodness of fit problems. In the current investigation, it is demonstrated that a goodness of fit approach is possible in many lifetesting problems and that It results in simpler procedures that are asymptotically equivalent or better than standard ones. They may also have superior finite sample behavior. Several perennial classes are addressed here. The class of increasing failure rate (IFR) and the class of new better than used (NBU) are addressed first. In addition, we provide testing for a newer and practical class of new better than used in convex ordering (NBUC) due to Cao and Wang (1991). Other classes can be developed similarly and this point is illustrated with the classes of new better than used in expectation (NBUE) and harmonic new better than used in expectation (HNBUE).

• 대한임상독성학회지
• /
• 제6권2호
• /
• pp.142-145
• /
• 2008

Lamotrigine is a newer anti-epileptic drug for adjunctive treatment of refractory epilepsy, partial seizures, generalized tonic-clonic seizures, and bipolar disorder. Lamotrigine overdose causes serious central nervous and cardiovascular problems, but reports are uncommon. Few lamotrigine overdoses have been described because anti-epileptic drug use is limited and usually used with combination of other anti-epileptic drugs. In addition, most patients visit emergency departments with multi-drug overdoses, so few cases of lamotrigine poisoning alone exist. We had a female patient visit our emergency department a couple of hours after a lamotrigine overdose treated with intravenous hydration and urine alkalization by NaHCO3. She recovered successfully without any evidence of renal injury. However, she developed profound rhabdomyolysis, a previously unreported complication of this medication. We suggest that serial creatine kinase levels should be measured after lamotrigine poisoning.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제22권1호
• /
• pp.50-56
• /
• 2019

The incidence of pediatric inflammatory bowel disease (IBD) is increasing worldwide, especially in the developing countries. It differs from adult disease in clinical manifestations, especially with regard to genetic predisposition in monogenic IBD. Pediatric disease also have a tendency to show more aggressive inflammation and greater extent of lesion. Newer drugs such as anti-tumor necrosis factor ${\alpha}$ have been known to make a difference in treating pediatric IBD. Recent studies suggested that the patients with high risk factors might have some benefits from earlier use of biologics. To achieve treatment goals such as relieving symptoms, optimizing growth, and improving quality of life while minimizing drug toxicity, more research is needed to develop tools for risk stratification in the use of biologics for pediatric IBD.

• Journal of Genetic Medicine
• /
• 제15권2호
• /
• pp.49-54
• /
• 2018

Nuchal translucency is an important indicator of an aneuploid fetus in prenatal diagnostics. Previously, only the presence of aneuploid could be confirmed by conventional karyotyping of fetuses with thick nuchal translucency. With the development of genetic diagnostic techniques, however, it has been reported that subtle variations not detectable by conventional karyo-typing might occur in cases of pathologic clinical syndrome in euploid fetuses. One of the newer, high-resolution genetic methods in the prenatal setting is chromosomal microarray. The possible association between nuchal translucency thickness with normal karyotype and submicroscopic chromosomal abnormalities detectable by microarray has been studied. How and when to apply microarray in clinical practice, however, is still debated. This article reviews the current studies on the clinical application of microarray in cases of increased nuchal translucency with normal karyotype for prenatal diagnosis.

• 대한족부족관절학회지
• /
• 제22권3호
• /
• pp.83-90
• /
• 2018

Chronic lateral ankle instability occurs in 10% to 20% of individuals after acute ankle sprain. The management of chronic lateral ankle instability is traditionally conservative treatment in the acute phase. On the other hand, surgical intervention is considered if conservative treatment fails and the symptoms are ongoing. This review focuses on the surgical approaches to treatment of chronic lateral ankle instability, including $Brostr{\ddot{o}}m$ surgical techniques, with a review of the traditional procedure and newer techniques.

• 한국공간구조학회논문집
• /
• 제19권1호
• /
• pp.93-100
• /
• 2019

There has been considerable recent interest in deep learning techniques for structural analysis and design. However, despite newer algorithms and more precise methods have been developed in the field of computer science, the recent effective deep learning techniques have not been applied to the damage detection topics. In this study, we have explored the structural damage detection method of truss structures using the state-of-the-art deep learning techniques. The deep neural networks are used to train knowledge of the patterns in the response of the undamaged and the damaged structures. A 31-bar planar truss are considered to show the capabilities of the deep learning techniques for identifying the single or multiple-structural damage. The frequency responses and the elasticity moduli of individual elements are used as input and output datasets, respectively. In all considered cases, the neural network can assess damage conditions with very good accuracy.