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Update on the treatment of endometriosis

  • Kim, Sung Hoon;Chae, Hee Dong;Kim, Chung-Hoon;Kang, Byung Moon
    • Clinical and Experimental Reproductive Medicine
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    • 제40권2호
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    • pp.55-59
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    • 2013
  • Endometriosis is defined as the presence of functional endometrial tissue outside the uterus, causing diverse progressive symptoms such as infertility, pelvic pain, and dysmenorrhea. Although endometriosis has been described since the 1800s, the mechanisms responsible for its pathogenesis and progression remain poorly understood. It is well established that endometriosis grows and regresses in an estrogen-dependent fashion and the disease can be effectively cured by definitive surgery. However, prolonged medical therapy may be needed in most of the cases since conservative surgery is usually performed especially in young women. This treatment modality is often associated with only partial relief and/or recurrence of the disease. In the present review, up-to-date findings on the treatment of endometriosis will be briefly summarized. The outcomes of surgery in patients with endometriosis will be reviewed in terms of pelvic pain relief as well as infertility treatment largely based on recent Cochrane reviews and clinical reports. The efficacy of newer drugs including aromatase inhibitor, anti-tumor necrosis factor-alpha, and dienogest will be also reviewed based on recent clinical studies.

인두암과 식도암의 새로운 진단내시경 (New Diagnostic Techniques in Cancer of the Pharynx and Esophagus)

  • 조주영;조원영
    • 대한기관식도과학회지
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    • 제17권1호
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    • pp.14-18
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    • 2011
  • The diagnosis and treatment of early gastrointestinal cancers is the gastroenterologists' mission because of national cancer screening program in South Korea. The detection of early cancers is emphasized, because these were previously treated with surgical treatment can be currently cured with endoscopic treatment. Gastroenterologists who achieved at least on some level can make an exact diagnosis regardless of what type of endoscopy, but generally, there are some required conditions for an optimal diagnosis. First, clinically important lesions have to be detected easily. Second, the border and morphology of lesions have to be characterized easily. Third, lesions have to be diagnosed exactly. Precancers and early cancers are often subtle and can pose a challenge to gastroenterologists to visualize using standard white light endoscopy. The use of dye solutions aids the diagnosis of early gastrointestinal cancers, however, it is a quite cumbersome to use dye solutions all the time and the solution often bothers the exact observation by pooling into the depression or ulceration of the lesion. To overcome this weakness, newer endoscopes are now developed so called "image enhanced endoscopy" using optical and/or electronic methods such as narrow band imaging (NBI), autofluorescence imaging (AFI), i-scan, flexible spectral imaging color enhancement (FICE) and confocal endomicroscopy (CLE).

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Human Capacity Issues Along the STEM Pipeline

  • Melkers, Julia
    • STI Policy Review
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    • 제1권2호
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    • pp.1-18
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    • 2010
  • The development and maintenance of human capacity in economies is critical to long term competitiveness, but also for the overall health and environment of regions. Yet, human science and technology-based capacity is multidimensional and has interrelated characteristics which present certain policy challenges. This paper addresses a range of issues specific to a discussion on human capacity in S&T. First, the paper emphasizes the importance of acknowledging the complexity of human capacity issues and how they evolve along the STEM (science, technology, engineering, and mathematics) pipeline. The pipeline is an often used reference to describe the training and development in STEM disciplines, from early childhood education, to more advanced training, and finally to professional collaboration and interaction and serves as a useful organizing framework for the discussion of capacity along the career evolution process. Second, the paper offers an organizing framework for discussion of policy mechanisms that have been developed to address issues and gaps that occur along this STEM pipeline. Specifically, it contrasts the traditional mechanisms of building human capacity in STEM areas with newer "gap filling" and integrated approached to addressed human capacity disparities and priorities. Third, the paper addresses core challenges in human capacity in STEM, including the education and training, participation of women and underrepresented groups, brain drain/brain circulation issues, and the globalization of science. The paper concludes with a discussion of policy implication for the development of human capacity.

Energy Efficiency & Sustainability the Cleanliness Management Role of Components and System in Automotive and Hydraulics

  • 홍정희;마이크데이
    • 드라이브 ㆍ 컨트롤
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    • 제9권4호
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    • pp.19-25
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    • 2012
  • This paper explains how eliminating contamination from the manufacturing processes will lead to better product quality and hence the need for reworking, a trouble free commissioning period and greatly improved production efficiency. All of these will reduce costs and energy usage. It will also ensure that the product is delivered to the customer in a condition that will ensure improved reliability and longer life, again reducing both energy and other operating costs. Correctly designing the contamination control measures will achieve and maintain the level of fluid cleanliness that is required by the end user. The filter is critical to cleanliness management and should be selected with the same degree of thought and consideration as for other major components. This paper explains the role that Cleanliness Management plays in the reducing the carbon footprint of systems and processes by making them perform more efficiently for longer periods. It also examines two differing ways of selecting filters to incorporate the features of newer designs, and shows how significant savings in the costs of ownership can be achieved using these approaches.

ADC-Based Backplane Receivers: Motivations, Issues and Future

  • Chung, Hayun
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제16권3호
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    • pp.300-311
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    • 2016
  • The analog-to-digital-converter-based (ADC-based) backplane receivers that consist of a front-end ADC followed by a digital equalizer are gaining more popularity in recent years, as they support more sophisticated equalization required for high data rates, scale better with fabrication technology, and are more immune to PVT variations. Unfortunately, designing an ADC-based receiver that meets tight power and performance budgets of high-speed backplane link systems is non-trivial as both front-end ADC and digital equalizer can be power consuming and complex when running at high speed. This paper reviews the state of art designs for the front-end ADC and digital equalizers to suggest implementation choices that can achieve high speed while maintaining low power consumption and complexity. Design-space exploration using system-level models of the ADC-based receiver allows through analysis on the impact of design parameters, providing useful information in optimizing the power and performance of the receiver at the early stage of design. The system-level simulation results with newer device parameters reveal that, although the power consumption of the ADC-based receiver may not comparable to the receivers with analog equalizers yet, they will become more attractive as the fabrication technology continues to scale as power consumption of digital equalizer scales well with process.

Is China a Trade Competitor of ASEAN? A Chinese Perspective on the Proposing, Cultivation and Implications of the CAFTA

  • WANG, Liqin
    • Journal of Contemporary Eastern Asia
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    • 제10권2호
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    • pp.1-23
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    • 2011
  • China's proposal of the CAFTA (China-ASEAN Free Trade Area) in 2001 prompted a great debate about whether China was a trade competitor of ASEAN, given their similarity in economic development levels and trade/export structures. That Beijing shifted its focus on economic cooperation from the international level to the regional level led to its proposal of the CAFTA. As the Framework Agreement (Framework Agreement on Comprehensive Economic Cooperation between China and ASEAN) showed, Beijing's careful consideration for four newer ASEAN members (Cambodia, Laos, Myanmar and Vietnam) intended not only to help all ASEAN members develop economically, but also to narrow the economic gap existing between them and the six old ASEAN members; in return, China was recognized as a full market economy, which it is not currently recognized within the framework of the WTO. The substantial rise in bilateral trade and the structural changes of the trade in goods between China and ASEAN member nations after 2001 proves that ASEAN benefited more from the CAFTA, particularly when the areas where ASEAN had the comparative advantages were designated as the priority cooperation areas between China and ASEAN. In sum, similarities existing in economic development levels and industrial structures between China and ASEAN made them natural economic competitors. However, closer studies of trade in goods of S1-7, S1-6 and S1-0 reveal that China acted as an increasingly complementary trade partner of ASEAN after 2001.

게임콘텐츠에서 묘사된 한국 캐릭터·스테이지의 문화적 영향 (The Cultural Effect of Korean Characters and Stages described in Game Contents)

  • 이창섭;이현정;김향미
    • 한국게임학회 논문지
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    • 제17권3호
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    • pp.83-92
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    • 2017
  • 게임유저는 게임콘텐츠에서 묘사된 정보를 바탕으로 특정 국가에 대한 문화적 이미지를 형성한다. 대전액션게임은 다양한 게임콘텐츠 장르 중 하나이며, 대게 국가별 게임캐릭터와 게임스테이지를 제공한다. 본 연구에서는 대전액션게임인 킹오브파이터즈(King of Fighters, KOF) 시리즈에서 묘사된 한국인 게임캐릭터와 한국의 게임스테이지를 살펴봄으로서, 게임유저가 형성할 수 있는 한국의 문화적 이미지에 대하여 분석하였다. 초기의 KOF94부터 KOF2003까지 총 10개의 KOF시리즈를 연구한 결과, KOF시리즈 초기작에서는 한국의 문화적 이미지가 매우 부정적으로 묘사되었음이 관찰되었다. 그러나 이러한 한국문화에 대한 부정적인 측면은 새로운 시리즈가 발매될수록 감소되었으며, 특히 국내 기업의 자금을 지원받아 제작된 KOF2001과 KOF2002에서는 한국의 긍정적인 문화적 이미지가 강화되었음을 확인하였다.

현대패션에 나타난 아트모드에 관한 연구 (A Study of the Art Mode in Modern Fashion)

  • 김선영
    • 복식
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    • 제59권8호
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    • pp.1-14
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    • 2009
  • This study was aimed to make clear fashion is an expression art displaying not only functional or commercial aspects, but creative functions as an artistic work by analyzing Art Mode and its values, and to help develop more creative design by combining fashion with art. In terms of method, relevant documents, precedent studies, and the works announced in domestic and foreign fashion collections, such as Vogue, Fashion News, Gap, and Collections from 2000 to 2009. According to the findings, artistic works were used by the Art Mode in modern fashion. The respect of artists was expressed using historic famous painting works or current works in various fields, designers' individuality was shown by directly applying work messages to clothes, and fashion design was converted into a tool to communicate the messages like artistic works. Second, the various styles, using the formative character of modern art styles from animalism to modern abstractism, showed the creativity of design, transformed art into the art that enables to see the image of modern art, and presented the possibility of developing into a newer creative design through the application of numerous art styles and the transformation of ideas. Third, the collaboration with artists was used. Fashion designers or fashion brands tried to change the images of works or brands in partnership with artists or to increase differentiated images. The future direction of fashion is a pursuit of new form and content to express fashion, not simply to use artistic works. It is expected that such pursuit will lead to more creative and artistic fashion design.

The technological state of the art of wave energy converters

  • GURSEL, K. Turgut
    • Advances in Energy Research
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    • 제6권2호
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    • pp.103-129
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    • 2019
  • While global demand for energy increases annually, at the same time the demand for carbon-free, sulphur-free and NOx-free energy sources grows considerably. This state poses a challenge in the research for newer sources like biomass and shale gas as well as renewable energy resources such as solar, wind, geothermal and hydraulic energy. Although wave energy also is a form of renewable energy it has not fully been exploited technically and economically so far. This study tries to explain those reasons in which it is beyond doubt that the demand for wave energy will soon increase as fossil energy resources are depleted and environmental concerns gain more importance. The electrical energy supplied to the grid shall be produced from wave energy whose conversion devices can basically work according to three different systems. i. Systems that exploit the motions or shape deformations of their mechanisms involved, being driven by the energy of passing waves. ii. Systems that exploit the weight of the seawater stored in a reservoir or the changes of water pressure by the oscillations of wave height, iii. Systems that convert the wave motions into air flow. One of the aims of this study is to present the classification deficits of the wave energy converters (WECs) of the "wave developers" prepared by the European Marine Energy Center, which were to be reclassified. Furthermore, a new classification of all WECs listed by the European Marine Energy Center was arranged independently. The other aim of the study is to assess the technological state of the art of these WECs designed and/or produced, to obtain an overview on them.

Shear strengthening of RC beams with Basalt Fiber Reinforced Polymer (BFRP) composites

  • Kar, S.;Biswal, K.C.
    • Advances in concrete construction
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    • 제10권2호
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    • pp.93-104
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    • 2020
  • Basalt fiber is an eco-friendly fiber and comparatively newer to the world of fiber-reinforced polymer (FRP) composites. A limited number of studies have been reported in the literature on the strengthening of reinforced concrete (RC) beams with basalt fiber reinforced polymer (BFRP). The present experimental work explores the feasibility of using the BFRP strips for shear strengthening of the RC beams. The strengthening schemes include full wrap and U-wrap. A simple mechanical anchorage scheme has been introduced to prevent the debonding of U-wrap as well as to utilize the full capacity of the BFRP composite. The effect of varying shear span-to-effective depth (a/d) ratio on the behavior of shear deficient RC beams strengthened with BFRP strips under different schemes is examined. The RC beams were tested under a four-point loading system. The study finds that the beams strengthened with and without BFRP strips fails in shear for a/d ratio 2.5 and the enhancement of the shear capacity of strengthened beams ranges from 5% to 20%. However, the strengthened beams fail in flexure, and the control beam fails in shear for a higher a/d ratio, i.e., 3.5. The experimental results of the present study have been compared with the analytical study and found that the latter gives conservative results.