• Title/Summary/Keyword: Newborns

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A novel association between cerebral sinovenous thrombosis and nonketotic hyperglycinemia in a neonate

  • Yurttutan, Sadik;Oncel, Mehmet Yekta;Yurttutan, Nursel;Degirmencioglu, Halil;Uras, Nurdan;Dilmen, Ugur
    • Clinical and Experimental Pediatrics
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    • v.58 no.6
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    • pp.230-233
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    • 2015
  • Lethargy in newborns usually indicates central nervous system dysfunction, and many conditions such as cerebrovascular events, infections, and metabolic diseases should be considered in the differential diagnosis. Nonketotic hyperglycinemia is an autosomal recessive error of glycine metabolism, characterized by myoclonic jerks, hypotonia, hiccups, apnea, and progressive lethargy that may progress to encephalopathy or even death. Cerebral sinovenous thrombosis is a rare condition with various clinical presentations such as seizures, cerebral edema, lethargy, and encephalopathy. Here, we report the case of a newborn infant who presented with progressive lethargy. An initial diagnosis of cerebral venous sinus thrombosis was followed by confirmation of the presence of nonketotic hyperglycinemia.

REPRODUCTION STUDIES WITH PRANOPROFEN: A NONSTEROIDAL ANTINFLAMMATORY AGENT IN RATS-PERINATAL AND POSTNATAL TEST.

  • Moon, Hwa-Hwey;Kim, Pu-Young;Cho, Dae-Hyun;Heo, Ok-Soon;Park, Sook-Hee;Yoon, Tae-Bo;Kim, Soon han
    • Toxicological Research
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    • v.2 no.2
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    • pp.63-77
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    • 1986
  • prenatal and postanatal study on pranoprofen, as an antiinflammatory agent, was conducted by oral administration in Sprague-Dawley pregnancy rats from day 17 of gestation to day 21 of after delivery. Pranoprofen was intubated doses of 1.0, 2.5 and 5.0 mg/kg/day and dose of 5.0mg/kg/day of Indomethacin was used as positive control. After delivery, several study indexes such as length of gestation, No. of implantations, No. of live pups, No. of perinatal deaths, sex ratio and No. of malformation were checked and then all the newborns were feeded and investigated physical and behavioral changes.

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Congenital Hallux Valgus - One Case Report - (선천성 무지 외반증)

  • Kang, Ho-Jung;Sohn, Joon-Seok
    • Journal of Korean Foot and Ankle Society
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    • v.1 no.2
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    • pp.126-131
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    • 1997
  • Hallux valgus is a hereditary deformity whose natural history is influenced by intrinsic and extrinsic factors. The deformity is infrequently noticed in newborns and infants because of its trivial nature that does not draw attention. Because in childhood and adolescence this deformity usually does not lead to functional disability, it is seldom treated actively. Opinions differ concerning the causal relationship of these deformities and appropriate treatment. It is clear, however, that the deviated great toe continues to deform, and leads to a chain of anatomical and functional changes. Thus, the advantages of the immediate treatment is obvious, especially in infancy, when the foot is supple. We are reporting one case of congenital hallux valgus with brief review of literature.

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Evaluation of function and disorders of the adrenal gland in neonates (신생아에서의 부신기능 평가와 질환)

  • Hwang, Il Tae
    • Clinical and Experimental Pediatrics
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    • v.50 no.3
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    • pp.236-240
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    • 2007
  • Majority of sick full term newborns have adequate adrenal cortical function in response to stress. Acutely ill neonates with a basal cortisol level less than $15{\mu}g/dL$ (414 nmol/L) suggest adrenal insufficiency and require function testing of adrenal function. In premature infant, immaturity of hypothalamic-pituitary adrenal axis (HPA axis), may limit the ability to increase cortisol production in response to stress. The response to low dose ACTH and CRH appears to be useful as an additional test of adrenal function. CRH stimulation has been used increasingly in neonates. The ACTH and CRH stimulated cortisol response of more than $17{\mu}g/dL$ (469 nmol/L) indicates a normal response.

Early-Onset Sepsis Due to Listeria Monocytogenes in a Extremely Low Birth Weight Infant (초극소 저출생 체중아에서 발생한 Listeria Monocytogenes에 의한 조발형 패혈증 1례)

  • Moon, Jin Hwa;Oh, Sung Hee;Moon, Soo Jee
    • Pediatric Infection and Vaccine
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    • v.7 no.2
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    • pp.245-249
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    • 2000
  • Listeria monocytogenes is one of the important causes of neonatal sepsis and listerial neonatal infection manifests in two forms : Early-onset sepsis syndrome, associated with spontaneous abortion, still birth, preterm labor, granulomatosis infantiseptica, respiratory distress, sepsis, hemodynamic compromise and late-onset listerosis mainly associated with meningitis. Cases of neonatal listerosis reported in Korea have been rare and all were full term newborns. We, herein, report a case of early-onset sepsis due to L. monocytogenes in a extremely low birth weight infant who were born in a critical condition and succumbed in the second day of life despite the intensive care.

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A Case of Neonate with benign Convulsion without Gastrointestinal Manifestations is Associated with Rotavirus Infection (위장관 증상이 없는 로타바이러스 감염에 동반된 신생아 경련 1례)

  • Kim, Young Jin;So, Kyoung Jin;Ma, Sang Hyuk
    • Pediatric Infection and Vaccine
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    • v.11 no.2
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    • pp.198-201
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    • 2004
  • Rotavirus is a most common etiologic viral agent of pediatric gastroenteritis. Most newborns infected by rotavirus show no specific symptoms, yet, some of neonates can develop serious complications such as intestinal perforation, necrotizing enterocolitis or even death. And rotavirus infection may cause only neurologic manifestation such as seizure without gastrointestinal manifestations in some neonates. We experienced a case of neonatal rotavirus infection with benign convulsion without gastrointestinal manifestations, and report this case with literature review as followings.

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The Study on the Influence of Factors on Clothing Purchase Behavior of Baby′s Wear (乳兒服 구매행동에 영향을 미치는 外的變數에 관한 연구)

  • 서미아;유성순
    • The Research Journal of the Costume Culture
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    • v.3 no.1
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    • pp.65-82
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    • 1995
  • The purpose of this research is to grasp the factors behind a mother's behavior in purchasing baby's clothes and to investigate how her purchasing behavior is affected by the baby's age, sex, rank, her age, her educational background, her place of residence, her occupation, the number of children's and family's monthly income. for this purpose, questionnaires were used and personal interviews with 481 mothers who bring up from newborns to two-year-old babies in Seoul ere conducted. Through this research, some facts have been found as follows. 1. Mother's behavior in purchasing baby's clothes are affected by baby's variables such as the baby's age, sex and rank, particularly it is much affected by baby's rank. 2. Mother's behavior in purchasing baby's cloths are affected by mother's variables such as the mother's age, educational background, place of residence, occupation, the number of children's and family's monthly income. Particularly it is much affected by mother's educational background and family's monthly income.

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Lipid Contents of Serum and Fatty Acid Composition of Serum Cholesteryl Esters in Mothers and Newborns (산모와 신생아의 혈청 지질 분획과 콜레스테릴 에스텔의 지방산 조성)

  • 이인자;조경열;정지윤;김정철;정태호
    • YAKHAK HOEJI
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    • v.28 no.2
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    • pp.79-87
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    • 1984
  • Lipid consumption in early life has been implicated with arteriosclerosis in later life. It has been also claimed that lipid contents of serum in early life would reflect coronary atherosclerosis in later life. Present study has been undertaken to look for serum lipid contents of mother and newborn simultaneously to determine the difference of various lipid classes. Lipids were extracted by Folch method. Total lipid was determined gravimetrically; cholesterol by Zak's method, phospholipids by Fiske-Subba-Row's method, and triglycerides by Sugiura's method. Fatty acids were analysed by gas liguid chromatography. Values of the total lipids of mother was significantly higher than those of newborn. HDI-cholesterol/total cholesterol ratio of newborn's was higher than mother's. The amount of saturated fatty acids in the serum cholesteryl ester of newborn was significantly higher than mother's.

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Biological Studies on the Newborns from Maternity Hospitals(II) (산원분만아에 대한 생물학적 연구(I)-사산 및 쌍생아산에 대하여)

  • 강영선;조완규;이인세
    • The Korean Journal of Zoology
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    • v.5 no.2
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    • pp.5-8
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    • 1962
  • 한국내 수개 도시에 있는 산원에서 자료를 얻을 수 있던 15,830의 생아 및 사산의 기록을 가지고 사산의 기록을 가지고 사산율 및 쌍생아산율을 고찰하였다. 사산율은 3.525%로 일어나고 있으며 모친의 연령이 36세 이상에서는 평균 사산율보다 약 2 배에 가까운 고율을 보여주고 있다. 사산아의 성비는 생아출산의 성비보다 훨씬 높아 136.06 이었다. 산원에서의 쌍생아산도 일반쌍생아산에 비해 더 빈번히 일어나고 있다. 즉 한국인 집단의 평균 쌍생아산의 율이 0.872인데 대하여 산원에서는 1.299%를 보여주고 있다. 모친의 연령이 증가하여 감에 따라 쌍생아산의 율이 상승하는 경향은 산원의경우에서 관찰할 수있었다. 쌍생아의 성조성에 따른 비율은 대체로 일반 집단에서나 산원의 것에서나 비슷하여, 1.49 남남 ; 1.09여여 이 었다. 이는 일본의 2 : 1 : 2 나 구주인계의 0.9 ; 1 : 0.9 의 중간의 비율을 나타내고 있다. 이란성 상생아에 대한 일란성쌍생아의 비율은 산원에서 0.79 : 1 일반 집단에서 0.75 : 1 이었다. 이 율도 결국 일본의 1.5 ; 1 . 구주인계의 0.5 : 1 의 거의 중간을 나타내고있는 것이다.

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A Pediatric Case of AVPR2-related Nephrogenic Syndrome of Inappropriate Antidiuresis

  • Bae, Hyunwoo;Baek, Hee Sun;Jang, Hae Min;Lee, Eun Joo;Cho, Min Hyun
    • Childhood Kidney Diseases
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    • v.24 no.2
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    • pp.126-130
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    • 2020
  • Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is a rare X-linked genetic condition caused by a gain-of-function mutation of arginine vasopressin receptor 2 gene, AVPR2. We report the case of a male neonate diagnosed with NSIAD based on his DNA sequence of the AVPR2 gene and the clinical course. He demonstrated a complete correction of hyponatremia using oral urea. We suggest that (1) sequencing analysis of the AVPR2 gene ought to be done in newborns with prolonged euvolemic hyponatremia, hypo-osmolality, high urinary sodium and normal/low or undetectable AVP levels, and that (2) oral urea is a safe and effective treatment option in infants diagnosed with NSIAD until the patients are grown-up.