• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.3 no.1
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• pp.147-157
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• 1992

The fragile X syndrome, which is considered to be synonymous with the Martin-Bell syndrome, is a relatively common form of X-linked mental retardation. The syndrome seems to occure in many different ethnic groups and its prevalence among mentally retarded males has been estimated to be in the order of 2 to 6%. The karyotypic hallmark of the syndrome is made up with a pronounced constriction near each tip of the long arm of the X chromosome(fragile site), shown in vitro only under conditions in which thymidylate production is blocked(lowered folate levels). Special culture media are needed to demonstrate this constriction site. Major clinical features associated with the syndrome include macroorchidism, large or prominent ears, significant emotional and behavioral dysfunctions such as hyperactivity, self-injury, lack of eye contact and social interaction, schizophrenia, autism, etc., and speech and language dysfunctions ranging from nonverbal to verbal speech with moderate to severe expressive language delays. Some have minor clinical features in common such as an increase in birth weight high forehead, prognathism, increased head circumference in infancy and childhood which did not persist into adult life. The recent research findings have shown that the fragile X syndrome is associated with infantile autism. Many patients with the fragile X syndrome fulfill the diagnostic criteria for infantile autism. Therefore it is recommendable that any patient with developmental delays and autism or autistic manifestations should have a chromosomal analysis, including fragile X examination. In the present review, historical aspects, incidence, and clinical features are presented. Recent anecdotal reports of the association with autism and the clinical improvement following high dose folic acid treatment will be discussed.

• Korean journal of communication and information
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• v.36
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• pp.7-41
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• 2006

This study criticizes the wave of liberalization, privatization, thoughtless and uncontrolled over-competition in the electronic communication networks area. This criticism is based on the 'transport economics' on one side, the 'network neutrality debate' on the other side. Through these standpoints, this study insists that it needs to deal with a social agenda related to the problems such as unplanned and unbalanced development of electronic communication networks, double/tripple-investment in the communication industry, conflicts among network companies and the decline of public values. Also does this study stress on the new ideas in the electronic communication network policy and planning to manage these problems. Electronic communication networks are converging and their borders are blurred. As a result of these flows, the field of information technology, media and contents is faced with radical changes. These changes could be so critical and complicated that nobody can diagnose their multi-level implications. However, the one thing sure is that we should start from the communication networks to think and control a communication system. Therefore, we should discuss and plan the now-and-future of communication infrastructure and its management. we need not only a market mentality but also a socio-cultural mentality. In this respect, this study does insist that it requires the vision of digital democracy and democratic communication ecology to put the steps toward social communication system.

• Korean journal of communication and information
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• v.36
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• pp.135-161
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• 2006

The aim of this study is to examine who had participated as members of the editorial staffs and their role in the Independent. In spite of the historical significance of the Independent, this topic was not treated properly by related studies. Moreover many studies mainly based on the Philip Jaisohn's autobiography showed the tendency to overemphasize his role. This study tried to overcome the limitations of the existing studies by critical reinterpretation of the historical materials and some new documents. The result of this study shows that 9 persons participated in the Independent. They are Philip Jaisohn, Joo Si-kyung, Yoon Chi-ho, Homer B. Hulbert, Son Seung-yong, Lee Jun-il, Henry Gerhart Appenzeller, H. Emberley and George Cobb. Five person including Jaisohn were Koreans and the rest were foreigners. Hulbert took part in editing English edition confidentially during some month from the beginning. Son Seung-yong seems to be the only one man to participate from beginning to end. Lee Jun-il was not a editorial staff but a treasurer, and Cobb participated temporarily in proofreading. Hulbert and Cobb were not official staff.

• Korean Journal of Soil Science and Fertilizer
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• v.50 no.5
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• pp.357-368
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• 2017

To establish new metal groundwater standard, 5 metals such as aluminum, chromium, iron, manganese, and selenium were evaluated by Chemical Ranking Of groundWater pollutaNts (CROWN) including possibility of exposure, toxicity, interest factor, connection standard for other media, and data reliability. 430 groundwater samples in 2013 and 2014 were collected semiannually from 110 groundwater wells and they were analyzed for selenium, manganese, iron, chromium, and aluminum. For this study, 430 groundwater samples were categorized into 3 geological distribution features, such as igneous, metamorphic, and sedimentary rock region and geological background levels were divided by pre-selection methods. For the results, the average concentrations of aluminum, chromium, iron, manganese, and selenium in 430 groundwater samples were $0.0008mg\;L^{-1}$, $0.0001mg\;L^{-1}$, $0.174mg\;L^{-1}$, $0.083mg\;L^{-1}$, and $0.0004mg\;L^{-1}$, respectively. In addition, among various geologies, average concentration of selenium was the highest in igneous rock region, average concentrations of chromium, manganese and aluminum were the greatest in sedimentary rock region, and average concentration of iron was the most high in metamorphic rock region. As a result of the geological background concentration with pre-selection method, background concentrations of selenium and aluminum in groundwater samples were the highest from sedimentary rock as $0.0010mg\;L^{-1}$ and $0.0029mg\;L^{-1}$ and background concentrations of manganese and iron in groundwater samples were the greatest from metamorphic rock as $0.460mg\;L^{-1}$ and $1.574mg\;L^{-1}$, and no chromium background concentration in groundwater samples was found from all geology.

• Journal of Industrial Convergence
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• v.18 no.5
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• pp.42-53
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• 2020

This study approached the elderly in Korea with a systematic review to find out the effect of virtual reality program arbitration on balance, which the evidence for the virtual reality program is provided. Total of 94 papers were searched through the database Nuri Media (DBpia), Scholarship (earticle), Korean Studies Information (KISS), National Digital Science Library (NDSL), the Korea Educational Research and Information Service (RISS), Kyobo Book Scholar (RISS), and Hakjisa New Thesis on Literature Selection using PRISMA flow-chart from January 2005 to May 2020 based on the final literature selection process and analysis. The quality level of the literature was found to be three volumes (50.0%) of the base level I, one (16.7%) of the II, and two of the III (33.3%). The most common type of virtual reality program was Wii-fit balance of 4 (66.7%), and the effect of virtual reality program arbitration was significant overall through evaluation tools for balance and walking ability. This is expected to effectively apply the virtual reality program to the elderly. In addition, since clinical application basis has been provided, further studies applying various virtual reality program interventions need to be addressed.

• Journal of Korea Port Economic Association
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• v.28 no.3
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• pp.127-150
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• 2012

A survey showed that the public perception of the shipping industry's overall image and economic role was relatively positive. The survey revealed that public perception was mixed with respect to the multifaceted role of the shipping industry. Based on the results of this survey, this paper proposes three approaches to improving the public perception of the shipping industry. The organization contact approach includes establishing shipping institutes for city people, holding various events targeted at the public, establishing a shipping memorial hall, developing a shipping-related culture and tourism, reinventing the image of the shipping industry through a shipping-culture movement, and creating new views of the shipping industry by conducting formal education. The goods and services contact approach includes building a brand image for shipping services, providing B2C services, utilizing the national image for the shipping industry, and participating in international cooperation projects. The text contact approach includes B2B advertising, advertisements focused on the national economic and multifaceted role of the shipping industry, package advertisements for the shipping industry and related industries, the Internet and high-technology media, government-initiated PR activities regarding the multifaceted role of the shipping industry, and funding for advertising the shipping industry.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.2
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• pp.159-164
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• 2015

To identify new anti-inflammatory and whitening material, this study investigated the whitening and anti-inflammatory effects of the lyophilized powder from 6 oriental plant extracts (OPE; Citrus junos Tanaka, Mori cortex Radicis, Schisandra chinensis Baillon, Coix lachrymajobi var. mayuen, Angelica gigas NAKAI, and Sophora japonica L.) fermented with Streptococcus thermophilus by assessment of cytotoxicity on human dermal fibroblast, inhibitory effect of nitric oxide (NO) prodction, tyrosinase activity and melanin formation. The OPE was fermented with Streptococcus thermophilus at $37^{\circ}C$ for 2 days and the lyophilized powder was manufactured by freezing-dryer. OPE didn't show cytotoxicity at concentration of $500{\mu}g/mL$ using a cytopathic effect reduction method. OPE also exhibited inhibitory effect on nitric oxide (NO) prodction by Griess reagent system. Furthermore, OPE showed inhibitory effect on tyrosinase activity with dose dependent manner, and exhibited significant inhibition of melanin formation by measurement of melanin from culture media (p < 0.05). From these results, 6 OPE extracts showed anti-inflammatory and whitening effect and may be used as an active ingredient for cosmetics.

• Journal of Korean Society of Archives and Records Management
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• v.5 no.2
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• pp.153-165
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• 2005

China is a country with a long history. Chinese culture dates back thousands of years ago. Thousand years of history left the huge quantity of archival heritage, which consists of the memory of China. From tied knots, tortoise shell, bronze, bamboo to paper, film, CD, the mankind's history is kept and continued through the evolution of the documenting media and documenting methods. In the information era, when we are immersed in the sea of information technologies, archivists, as guards of human's memory, have to look for a balance point between new and old, between unchanged and changed. On one hand, archivists should try their best to protect traditional archives in a usable, authentic way in a long term; on the other hand, they must face the challenges posed by electronic record. The information age is a stage of the social development of mankind, the digitalization of archives is an important progress of human history. The report mainly is composed of three parts of the content: first, introduce the preserving situation of Chinese archival heritage ; focus are put on "China archival heritage program" and the construction of "Special archives repository"; second, the process of digitalization of traditional archives; third, the framework of electronic record standard.

• Journal of the Korea Convergence Society
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• v.8 no.9
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• pp.1-7
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• 2017

As the network environment develops and speeds up, a lot of smart devices is developed, and a high-speed smart society can be realized while allowing people to interact with objects. As the number of things Internet has surged, a wide range of new security risks and problems have emerged for devices, platforms and operating systems, communications, and connected systems. Due to the physical characteristics of IoT devices, they are smaller in size than conventional systems, and operate with low power, low cost, and relatively low specifications. Therefore, it is difficult to apply the existing security solution used in the existing system. In addition, IoT devices are connected to the network at all times, it is important to ensure that personal privacy exposure, such as eavesdropping, data tampering, privacy breach, information leakage, unauthorized access, Significant security issues can arise, including confidentiality and threats to facilities. In this paper, we investigate cases of security threats and cases of network of IoT, analyze vulnerabilities, and suggest ways to minimize property damage by Internet of things.

• Journal of Life Science
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• v.15 no.4 s.71
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• pp.652-656
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• 2005

Tuberculosis is the leading infectious disease in the world. It is urgent to develop new vaccine and treating drugs. Besides vaccines, we want to know the effects of regular swim training on TB infection in the mouse model. This study was designed to examine the effects of regular swim training on lung and spleen TB counts and $INF-\gamma$ activity in the trained mice at different temperature. The trained mice underwent a 10-wk endurance swim training (5 times/wk) in water at $29\~33^{\circ}C$ (WWG) and $21\~23^{\circ}C$(CWG) for 60 min. And they were divided into 3 groups according to the regular swim training (CG; control, WWG; warm water group, and CWG; cold water group). Mice were challenged by aerosol infection with M. tuberculosis H37Rv using an inhalation device (Glas-Col, Terre Haute, Ind.) calibrated to deliver bacteria into lungs. Three weeks after immunization, the mice were challenged. Four weeks after challenge, the mice were sacrificed and the numbers of viable bacteria in lung and spleen were determined by plating serial dilution of whole organ homogenates on nutrient Middlebrook 7H11 agar (Difco, Detroit, MI). Colonies were counted after four weeks incubation at $37^{\circ}C$. All data were expressed as mean, standard deviation by using SPSS package program (win 10.0). The result through the statistical analysis of this data were summarized as follows; In the weight changes, there were significant differences among CG, WWG, and CWG following the swim training at different temperature, and CWG was the lowest. In the change of $INF-\gamma$ following the swim training, there were significant differences (p<.05) among CG, WWG, and CWG after stimulated with media and CFP. In MTB counts, there were significant differences (p<.05) between CG and WWG in the lung. And also there were significant differences (p<.05) among CG, WWG, and CWG. These results suggest that regular swim training suppress Th1 immune response caused by decreased $INF-\gamma$ level in the WWG, Also For the WWG, highly increased level of TB counts appear in the lung and spleen compare to CG.