• Title/Summary/Keyword: New derivative

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A NOTE ON INEXTENSIBLE FLOWS OF CURVES WITH FERMI-WALKER DERIVATIVE IN GALILEAN SPACE G3

  • Bozok, Hulya Gun;Sertkol, Ipek Nizamettin
    • Honam Mathematical Journal
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    • v.42 no.4
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    • pp.769-780
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    • 2020
  • In this paper, Fermi-Walker derivative for inextensible flows of curves are researched in 3-dimensional Galilean space G3. Firstly using Frenet and Darboux frame with the help of Fermi-Walker derivative a new approach for these flows are expressed, then some results are obtained for these flows to be Fermi-Walker transported in G3.

Characterization of Antibacterial activity and Synthesis of Sulfanilamide Polymer using Crosslinking Agent (가교제를 이용한 Sulfanilamide 중합체의 합성과 항균특성)

  • Kim, Jong-Woan;Yoon, Chul-Hun;Hwang, Sung-Kwy;Kong, Seung-Dae;Lee, Han-Seab
    • Journal of the Korean Applied Science and Technology
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    • v.17 no.1
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    • pp.37-42
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    • 2000
  • Drug delivery system(DDS) have been actively studied for the past twenty years. Dual action agents are unique chemical entities comprised of two different types of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. In spite of the advent of the antibacterial agent the sulfa agents are the most widely used antibacterial agent today. In this study, new antibacterials derivative was synthesized using glutaraldehyde such as crosslinking agent for the purpose of dual-action as DDS study. Antibacterial activity of these new synthetic derivative between their structures and activities were examined by disc diffusion method. As a result, new synthetic derivative exhibited the broad antibacterial activities against Gram(+) and Gram(-) bacilli. Especially, the antibacterial effect of new synthetic derivative against Gram negative(Esherichia. coli) was much stronger than that against Gram positive.

A Novel Non-contact Measurement Method for the Detection of Current Flowing Through Concealed Conductors

  • Yang, Fan;Liu, Kai;Zhu, Liwei;Hu, Jiayuan;Wang, Xiaoyu;Shen, Xiaoming;Luo, Hanwu;Ammad, Jadoon
    • Journal of Magnetics
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    • v.22 no.1
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    • pp.43-48
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    • 2017
  • In order to detect the current flowing through concealed conductor, this paper proposes a new method based on derivative method. Firstly, this paper analyzes the main peak characteristic of the derivative function of magnetic field generated by a current-carrying conductor, and a relationship between the current flowing through the conductor and the main peak of the derivative function is obtained and applied to calculate the current. Then, the method is applied to detect the conductor current flowing through grounding grids of substations. Finally, the numerical experimental and field experiment verified the feasibility and accuracy of the method, and the computing results show that the method can effectively measure the conductor current of grounding grids with low error, and the error is within 5 %.

The Effects of Enamel Matrix Derivative and Calcium Sulfate Paste on the Healing of 1-Wall Intrabony Defects in Beagle Dogs (성견 1면 치조골 결손부에서 $Emdogain^{(R)}$$Emdogain^{(R)}$ 및 특수 제조된 Calcium Sulfate Paste 혼합물이 치주조직 치유에 미치는 영향)

  • Choi, Seong-Ho;Kim, Chang-Sung;Suh, Jong-Jin;Kim, Hyun-Young;Kim, Jeong-Hye;Cho, Kyoo-Sung;Kim, Chong-Kwan
    • Journal of Periodontal and Implant Science
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    • v.30 no.3
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    • pp.539-555
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    • 2000
  • Recently, it was reported that enamel matrix derivative may be beneficial in periodontal regeneration procedures in expectation of promoting new bone and cementum formation. The aim of present study was to evaluate the effect of enamel matrix derivative($Emdogain^?$)and Caso4 sulfate paste in 1-wall intrabony defects in beagle dogs. Surgically created 1-wall intrabony defects were randomly assigned to receive root debridement alone or $Emdogain^{(R)}$ or $Emdogain^{(R)}$ and Caso4. Clinical defect size was 4 X 4mm. The control group was treated with root debridement alone,and Experimental group I was treated with enamel matrix derivative application, and Experimental group II was treated with enamel matrix derivative and Caso4 sulfate paste application,. The healing processes were histologically and histometrically observed after 8 weeks and the results were as follows: 1. The length of junctional epithelium was $0.41{\pm}0.01mm$ in the control group, $0.42{\pm}0.08mm$in the experimental group I and $0.50{\pm}0.13mm$in the experimental group II. 2. The connective tissue adhesion was $0.28{\pm}0.02mm$ in the control group, $0.13{\pm}0.08mm$ in the experimental group I and $0.19{\pm}0.02mm$ in the experimental group II. 3. The new cementum formation was $3.80{\pm}0.06mm$ in the control group, $4.12{\pm}0.43mm$ in the experimental group I and $4.34{\pm}0.71mm$ in the experimental group II. 4. The new bone formation was $1.43{\pm}0.03mm$ in the control group, $1.53{\pm}0.47mm$ in the experimental group I and $2.25{\pm}1.35mm$ in the experimental group II. Although there was limitation to present study, the use of enamel matrix derivative in the treatment of periodontal 1-wall intrabony defect enhanced new cementum and bone formation. Caso4 sulfate paste will be the candidate for carriers to deliver enamel matrix derivative, and so enhance the regenerative potency of enamel matrix derivative.

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Brahol : A New Derivative of allo-Inositol from Stocksia brahuica

  • Ahmad, Viqar Uddin;Ali, Zulfiqar;Ali, Muhammad Shaiq;Zahid, Muhammad;Tareen, Rasool Bakhsh
    • Natural Product Sciences
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    • v.4 no.3
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    • pp.170-173
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    • 1998
  • A new derivative of allo-inositol has been isolated from the aerial parts of Stocksia brahuica and named as brahol (1). The structure of 1 was elucidated with the help of extensive 2D-NMR spectroscopic techniques and identified as 5-O-methyl-allo-inositol. The structure was reconfirmed by acetate derivative (2).

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Tribological Properties of Aqueous Solutions Composed of Aminated Olive Oil Derivative (수용성 아민화 올리브유 유도체의 트라이볼로지적 특성고찰)

  • Choi, Ung-Su;Lee, Sang-Soon
    • Tribology and Lubricants
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    • v.26 no.5
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    • pp.272-276
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    • 2010
  • Aminated oilve oil derivative as the new organic disperse phases of the water soluble metal working fluid has been synthesized and tribological properties of the aqueous solutions composed of aminated olive oil derivative investigated using Four Ball Wear Tester and Falex EP Tester. The formulated aqueous solutions showed higher antiwear and extreme pressure properties and also lower friction coefficient. On the basis of the the results, water soluble aminated oilve oil derivative showed excellent tribological properties due to the polarizability of oleic acid derivative composed of majority part in oilve oil.

Benzastatin J, a New Demethylated Derivative of Benzastatin B Produced by Controlled Fermentation of Streptomyces nitrosporeus

  • Kim, Won-Gon;Yoo, Ick-Dong
    • Journal of Microbiology and Biotechnology
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    • v.12 no.5
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    • pp.838-840
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    • 2002
  • Feeding experiments of various derivatives of p-aminobenzamide to benzastatins-producing Streptomyces nitrosporeus were performed to observe whether new biosynthetic analogs of benzastatins were produced. The supplementation of p-aminobenzoic acid to the culture medium of Strepromyces nitrosporeus led to the production of benzastatin J, a new demethylated derivative of benzastatin B, while production of benzastatins A and B increased and benzastatins C-G were not detected.

New Cytotoxic Metabolites from a Marine Sponge Homaxinella sp.

  • Mansoor Tayyab A.;Hong, Jong-Ki;Lee, Chong-O;Sim, Chung-Ja;Im, Kwang-Sik;Jung, Jee H.
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.190.3-190.3
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    • 2003
  • Three new butenolides (1-3), and a new cyclopentenone derivative (4) were isolated from a marine sponge Homaxinella sp. by bioactivity guided fractionation. The gross structures were established on the basis of NMR and MS analyses. The stereochemistry of the butenolides and cyclopentenone derivative was defined on the basis of optical rotation and CD spectroscopy. The compounds were tested against a panel of five human solid tumor cell lines and displayed marginal to significant cytotoxicity.

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The effects of enamel matrix derivative on the healing of 1-wall intrabony defects in beagle dogs (성견의 1면 골결손부에서 법랑기질 유도체가 치주조직 치유에 미치는 영향)

  • Oh, Je-Ik;Choi, Seong-Ho;Lee, Seung-Won;Cho, Kyoo-Sung;Kim, Chong-Kwan;Chai, Jung-Kiu
    • Journal of Periodontal and Implant Science
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    • v.27 no.4
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    • pp.767-783
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    • 1997
  • Guided tissue regeneration, bone graft procedures, and application of growth factors have been used to regenerate lost periodontal tissues. Recently, enamel matrix derivative has been introduced into periodontal regeneration procedures in expectation of promoting new bone and cementum formation. The purpose' of this study was to evaluate the effect of enamel matrix derivative in 1-wall intrabony defects in beagle dogs. For this purpose, each dog was anesthesized using intravenous anesthesia and mandibular 1st, 3rd premolars were extracted. 2 months later, the 1-wall intrabony defects(mesio-distal width: 4mm, depth: 4mm) were created on the distal side of 2nd premolars and mesial side of 4th premolars. The control group was treated with debridement alone, and experimental group was treated with debridement and enamel matrix derivative application. The healing processes were histologically and histometrically observed after 8 weeks and the results were as follows : 1. The length of junctional epithelium was $0.94{\pm}0.80mm$ in the control group, $0.57{\pm}0.42mm$ in the experimental group, with no statistically significant difference between groups. 2. The connective tissue attachment was $1.36{\pm}0.98mm$ in the control group. $0.38{\pm}0.43mm$ in the experimental group, with statistically significant difference between groups(P<0.05). 3. The new cementum formation was $2.49{\pm}1.06mm$ in the control group, $3.59{\pm}0.74mm$ in the experimental group. with statistically significant difference between groups(P<0.05). 4. The new bone formation was $1.92{\pm}0.97mm$ in the control group, $2.32{\pm}0.59mm$ in the experimental group. with no statistically significant difference between groups. Within the limitation to this study protocol, enamel matrix derivative application in 1-wall intrabony defect enhanced new cementum formation. Although there was no statistically significant difference, enamel matrix derivative also seems to be effective in inhibition of apical migration of junctional epithelium and new bone formation.

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Derivative Evaluation and Conditional Random Selection for Accelerating Genetic Algorithms

  • Jung, Sung-Hoon
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.5 no.1
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    • pp.21-28
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    • 2005
  • This paper proposes a new method for accelerating the search speed of genetic algorithms by taking derivative evaluation and conditional random selection into account in their evolution process. Derivative evaluation makes genetic algorithms focus on the individuals whose fitness is rapidly increased. This accelerates the search speed of genetic algorithms by enhancing exploitation like steepest descent methods but also increases the possibility of a premature convergence that means most individuals after a few generations approach to local optima. On the other hand, derivative evaluation under a premature convergence helps genetic algorithms escape the local optima by enhancing exploration. If GAs fall into a premature convergence, random selection is used in order to help escaping local optimum, but its effects are not large. We experimented our method with one combinatorial problem and five complex function optimization problems. Experimental results showed that our method was superior to the simple genetic algorithm especially when the search space is large.