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Benzastatin J, a New Demethylated Derivative of Benzastatin B Produced by Controlled Fermentation of Streptomyces nitrosporeus  

Kim, Won-Gon (Korea Research Institute of Bioscience and Biotechnology)
Yoo, Ick-Dong (Korea Research Institute of Bioscience and Biotechnology)
Publication Information
Journal of Microbiology and Biotechnology / v.12, no.5, 2002 , pp. 838-840 More about this Journal
Abstract
Feeding experiments of various derivatives of p-aminobenzamide to benzastatins-producing Streptomyces nitrosporeus were performed to observe whether new biosynthetic analogs of benzastatins were produced. The supplementation of p-aminobenzoic acid to the culture medium of Strepromyces nitrosporeus led to the production of benzastatin J, a new demethylated derivative of benzastatin B, while production of benzastatins A and B increased and benzastatins C-G were not detected.
Keywords
Benzastatin; p-aminobenzoic acid; Streptomyces nitrosporeus; supplementation; demethylation;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 2  (Related Records In Web of Science)
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