Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Benzastatin J, a New Demethylated Derivative of Benzastatin B Produced by Controlled Fermentation of Streptomyces nitrosporeus

  • Kim, Won-Gon (Korea Research Institute of Bioscience and Biotechnology) ;
  • Yoo, Ick-Dong (Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2002.10.01
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Abstract

Feeding experiments of various derivatives of p-aminobenzamide to benzastatins-producing Streptomyces nitrosporeus were performed to observe whether new biosynthetic analogs of benzastatins were produced. The supplementation of p-aminobenzoic acid to the culture medium of Strepromyces nitrosporeus led to the production of benzastatin J, a new demethylated derivative of benzastatin B, while production of benzastatins A and B increased and benzastatins C-G were not detected.

Keywords

References

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