• Title/Summary/Keyword: New combination

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Hemihypertrophy with hypomelanosis of Ito: A new syndrome combination

  • Goswami, Hit K.;Rangnekar, Aruna G.;Sharma, Sandeep;Varshney, Subodh;Lee, In-Hwan;Chang, Sung-Ik
    • Journal of Genetic Medicine
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    • v.2 no.1
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    • pp.1-5
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    • 1998
  • A female hemihypertrophy patient with hypomelanosis of Ito is presented as a rare case combining classical features of both the syndrome. Chromosomal profile has been based on longitudinal study of repeated lymphocyte cultures during 1984-1992. The propositus has exhibited chromosomal mosaicism both hypoploid ($42{\pm}1$) and hyperploid ($48{\pm}2$ chromosome) counts, but the major stem line presented 46XX chromosomes. Ring chromosome with simple and complex translocations with marker dots appear to be the major cytogenetic assemblage of this child to posses unequal left and right halves of the body. Each and every organ from toe to the head has grown up unequally and lately the patient had been exhibiting different dark and light shapes of melanin on the skin. We believe that the patient had inherited, through her male parent, "a few" mutated loci on some chromosomes so as to generate different cell lines within the developing child. All sibs and the mother showed normal karyotype with no apparent aberration.

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Improving the Inventive Thinking Tools Using Core Inventive Principles of TRIZ (TRIZ의 핵심 발명원리를 이용한 발명적 사고도구의 개선)

  • Kim, Tai-Young;Kim, Jung-Hyeon;Park, Young-Taek
    • Journal of Korean Society for Quality Management
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    • v.46 no.2
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    • pp.259-268
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    • 2018
  • Purpose: SIT(Systematic Inventive Thinking) has been widely used in recent years. The validity of the five thinking tools of SIT is examined, and how to improve the inventive thinking tools is investigated. Methods: Frequency analysis on the usage of the TRIZ 40 inventive principles was used. Inventive thinking tools are derived by eliminating principles with low frequencies and grouping similar principles together. Results: Segmentation, prior action, combining, extraction, cushion in advance, transformation of properties are most frequently used among the 40 principles of TRIZ. The most frequently used principles and similar principles with them are grouped into new inventive thinking tools. Two of them, division and attribute dependency, belong to the 5 thinking tools of SIT, and the others, proactive measures, combination and reversal, do not. Conclusion: The newly identified inventive thinking tools are division, combination, proactive measures, attribute dependency, and reversal. The new five inventive thinking tools are quite efficient since they can cover more than two thirds of the TRIZ 40 inventive principles.

Efficient isolation, culture and regeneration of Lotus corniculatus protoplasts

  • Raikar, S.V.;Braun, R.H.;Bryant, C.;Conner, A.J.;Christey, M.C.
    • Plant Biotechnology Reports
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    • v.2 no.3
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    • pp.171-177
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    • 2008
  • This paper reports an improved protocol for isolation, culture and regeneration of Lotus corniculatus protoplasts. A range of parameters which influence the isolation of L. corniculatus protoplasts were investigated, i.e., enzyme combination, tissue type, incubation period and osmolarity level. Of three enzyme combinations tested, the highest yield of viable protoplasts was achieved with the combination of 2% Cellulase Onozuka RS, 1% Macerozyme R-10, 0.5% Driselase and 0.2% Pectolyase. The use of etiolated cotyledon tissue as a source for protoplast isolation proved vital in obtaining substantially higher protoplast yields than previously reported. Culture of the protoplasts on a nitrocellulose membrane with a Lolium perenne feeder-layer on the sequential series of PEL medium was highly successful in the formation of microcolonies with plating efficiencies 3-10 times greater than previous studies. Shoot regeneration and intact plants were achieved from 46% of protoplast-derived cell colonies.

Study of Connection Process in Distribution systems using Genetic Algorithm (배전계통에서 GA를 이용한 접속변경 순서 결정 방법)

  • Oh, Seon;Seo, Jeong-Kap
    • Journal of Satellite, Information and Communications
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    • v.6 no.1
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    • pp.6-11
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    • 2011
  • In this paper presents a new approach to evaluate reliability indices of electric distribution systems using genetic Algorithm (GA). The use of reliability evaluation is an important aspect of distribution system planning and operation to adjust the reliability level of each area. In this paper, the reliability model is based on the optimal load transferring problem to minimize load generated load point outage in each sub-section. This approach is one of the most difficult procedures and become combination problems. A new approach using GA was developed for this problem. GA is a general purpose optimization technique based on principles inspired from the biological evolution using metaphors of mechanisms such as natural selection, genetic recombination and survival of the fittest. Test results for the model system with 24 nodes 29 branches are reported in the paper.

The Assessment and Characteristics for Indoor Air Quality in Military Barracks (군 병영시설의 실내 공기질 평가 및 특성)

  • Kim, Suk-Bong;Jeong, Sang-Jo;Baek, Sang-Ho;Kim, Tae-Wook;Park, Young-Jun
    • Journal of the Korea Institute of Military Science and Technology
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    • v.10 no.4
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    • pp.168-175
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    • 2007
  • In this study, the Indoor Air Quality(IAQ) in military barracks is evaluated and its characteristics is discussed as well. The military barracks of R.O.K Army are categorized into three types and the IAQ in these individual facilities is measured for 24 hours both in summer and winter. Test results show that the particulate matters($PM_{10}$) and carbon dioxide($CO_2$) were the main causes contaminating IAQ in military barracks. While $CO_2$ can be purified by ventilation, adequate facilities have to be installed in case of the new type of combination barracks to remove $PM_{10}$. In addition, to improve the living condition of military barracks and to recover IAQ in new combination style barracks which is planned to complete by 2011, a standard or law regulating IAQ in military barracks has to be established.

Optimal Configuration Control for a Mobile Manipulator

  • Kang, Jin-Gu;Jin, Tae-Seok;Kim, Min-Gyu;Lee, Jang-Myung
    • Journal of Mechanical Science and Technology
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    • v.14 no.6
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    • pp.605-621
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    • 2000
  • A mobile manipulator-a serial connection of a mobile platform and a task robot-is redundant by itself. Using its redundant freedom, a mobile manipulator can move in various modes, i. e., can perform dexterous tasks. In this paper, to improve task execution efficiency utilizing redundancy, optimal configurations of the mobile manipulator are maintained while it is moving to a new task point. Assuming that a task robot can perform the new task by itself, a desired configuration for the task robot can be pre-determined. Therefore, a cost function for optimality can be defined as a combination of the square errors of the desired and actual configurations of the mobile platform and of the task robot. In the combination of the two square errors, a newly defined mobility of a mobile platform is utilized as a weighting index. With the aid of the gradient method, the cost function is minimized, so the tasle that the mobile manipulator performs is optimized. The proposed algorithm is experimentally verified and discussed with a mobile manipulator, PURL-II.

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Determinants of the Knowledge Combinative Capability Based on Social Capital Theory (사회적 자본의 관점에서 본 결합능력의 형성요인 -특허청 사례를 중심으로-)

  • Park, Rhoyun
    • Knowledge Management Research
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    • v.5 no.2
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    • pp.67-98
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    • 2004
  • New knowledge is created through the dynamic interaction of knowledge that depends largely on a social context within the organization. Social processes influence the nature of knowledge and learning. This paper is rooted in the concept of social capital. Social capital theory emphasizes the importance of social relationship. Using social capital theory, this paper suggests three factors that must be satisfied for the development of knowledge combinative capability. The first factor is that the opportunity exists to make the exchange or combination of knowledge. The second factor is that people is motivated for the creation of new knowledge. The third factor is that people must share the common knowledge. This paper examines the change case of KIPO (Korean Intellectual Property Office). This case provides evidence that the three factors can develop social relationship, and build knowledge combinative capability. The man finding from this research is that social factors play an important part in the creation of knowledge, and processes of knowledge exchange and combination heavily rely upon social patterns, practices and processes in ways which emphasize the value and importance of collective action and knowledge sharing. This research may have several implications for the development of the knowledge creation mechanisms.

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Land Suitability Classification for Rational Land Use Planning in County(Gun) Area( I ) - Methodological Considemtion of Land Suitability Classification - (군단위지역 토지이용계획의 합리적 책정을 위한 토지적성구분( I ) - 토지적성구분의 방법론적 고찰 -)

  • Hwang, Han-Cheol;Choe, Su-Myeong;Han, Gyeong-Su
    • Journal of Korean Society of Rural Planning
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    • v.1 no.1
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    • pp.65-74
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    • 1995
  • As a initial methodological approach to rational land use planning in the county-level area, three types of land suitability classification techniques were examined from the viewpoint of their practical applicability through the case study of Seungju-gun area, Chonnam-province, Korea : major factors' criteria(method I ), principal component analysis( I ), and local monitoring( R( ). Each method has its strong and weak points as shown in Tab.-5. Therefore, when its practical application, there seem to be wide-range methodological selectivities from exclusive use of the best one to intermethodological combination of related ones In the beginning stage, intermethodological combination of all three types were tried to formulate the best solution possible. However, because of reliability problem of method R accrued from non- uniformity of evaluators'quality, only two methods( 1 , E ) were combined into a new evaluation method The applied results of the new combined method to case study area are shown in Fig.-2, 3 and 4.

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Cyborg Image Expressed in Fashion Illustration (패션 일러스트레이션에 표현된 사이보그 이미지)

  • Kim, Soon-Ja
    • Fashion & Textile Research Journal
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    • v.13 no.6
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    • pp.866-876
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    • 2011
  • We find ourselves living in a post-human era when technology and images coexist with humans. A cyborg, a combination of an organic body and a machine could be called a human fused with a machine. It could be understood as a new species where humans and machines have combined rather than simple protoplasm or an organic body. The purpose of this study is to demonstrate that a concept of a body in post humanism era is finding expression in fashion illustration through cyborg images. The concepts of post humanism and cyborg are analysed by means of research into literature and characteristics in which cyborg images as post humans are expressed through art, and images of a cyborg body in fashion illustration and their meanings are explored with the foregoing as a framework of reference. Cyborg image reflects new images and concept of a human in post humanism. The cyborg body images in fashion illustration are expressed through the addition of mechanical images, digital virtual body, monster image by means of hybrid combination, distorted physical transformation and fragmented body and body absence. And cyborg image in fashion illustration shows the extension of body concepts through the technology and uncertain and ambiguous identity.

Comparative Study on the Stability of Amoxicillin, Clavulanic Acid and its Commercial Combination Products (아목시실린, 클라불란 산 및 시판 아목시실린-클라불란 산 복합제제의 안전성 비교연구)

  • Han, Sang-Dug;Kim, Chong-Kook
    • YAKHAK HOEJI
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    • v.49 no.5
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    • pp.392-398
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    • 2005
  • In this study, we evaluated the stability of amoxicillin (AMX) and clavulanic acid (CLA) in aqueous solution, and compared the stability of AMX and CLA in commercial combination products. In aqueous solutions, the degradation of AMX ($t_{90}=8.88\;day\;at\;10^{circ}C$) and CLA ($t_{90}=3.53\;day\;at\;10^{circ}C$) occurred rapidly. From the pH-rate profile, AMX and CLA were the most stable at the range of pH 5.5 and 6.0. After reconstitution of commercial dry syrups, the contents of AMX and CLA in suspensions were gradually decreased for 7 days. However, AMX and CLA in dispersible tablet were not changed at all. The contents of CLA in the dispersible tablet ($87.92\%$) and dry syrups (2.16 and $3.91\%$) were remained in the accel­erated stability test ($75\%\;RH,\;at\;40^{circ}C$) after 10 hours. And the colors of the dry syrups were rapidly changed from white to yellow. From these results, we concluded that the dispersible tablet could overcome the stability problems of dry syrups.