• 패션비즈니스
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• 제2권1호
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• pp.12-24
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• 1998

The purpose of this study is to investigate the efficiency of systematic color combination for apparel and textile design. We planned the new color systems, HUE AND TONE COLOR SYSTEM 277 and HUE AND TONE COLOR SYSTEM 253 USED KOREAN TRADITIONAL COLORS. In order to emprove the efficiency, this study aims to explore the development of systematic color combination by computer graphics. With this purpose, this study progressed in the following order and we obtained these results. 1. First, we considered the possibility of the development of the systematic color combination used the new color system, HUE AND TONE COLOR SYSTEM 277. We considered the possibility of the development of the systematic color combination by graphic computer SDS-480. Through the experimental regulation of the RGB (Red, Green, Blue) and HLS (Hue, Lightness, Saturation) we obtained an approximation of the colors of the HUE AND TONE COLOR SYSTEM 277 on the CRT display of SDS-480. 2. We planned the new color system, HUE AND TONE COLOR SYSTEM 253 USED KOREAN TRADITIONAL COLORS for systematic color combination. 3. In a practical application, we tried five principal types of color combination in apparel and textile design, monochromatic combination, tone on tone combination, moderate combination, tonal combination, and contrast combination. 4. Furthermore, we applied the systematic color combination for the textile patterns by tone on tone combination. By using the systematic color combination for apparel and textile design, we realized the efficiency and utility of the systematic color combination.

• East Asian mathematical journal
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• 제36권5호
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• pp.555-560
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• 2020

We prove a new combination theorem for relatively hyperbolic groups by analyzing diagrams over HNN-extensions of relatively hyperbolic groups.

• KIEAE Journal
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• 제11권5호
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• pp.69-77
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• 2011

In order to solve social exclusion and segregation phenomenon and to realize social integration, the necessity of social combination and consensus has been presented and existing conception about the public lease apartment confronts a turning point due to the diversification of apartment supply system. With this social background, Eunpyeong New Town Project implemented by Seoul Metropolitan Government is the first example that supplied diverse apartments for social integration. Survey was made upon the residents aged 20 and over and living in combination apartments, lease apartments and common apartments for private ownership in the Enpyeong New Town Apartment Complex in section 1 area, and the survey sheets filled up by the respondents were collected by personal visits or by using specified gathering spots. Summary of study results is as follows: Firstly, regarding the combination method, respondents preferred the irregular combination of lease apartment units and common apartment units in the same apartment building at the top, analyzing by survey groups marked that residents of common apartment with initial ownership responded not to choose combination apartment complex or combination apartment in future. Secondly, the living consciousness with neighbors revealed that respondents were generally satisfied without difference between the residents of lease apartment and common apartment. As the demand and policies for diverse lease apartments are increasing recently, Eunpyeong New Town Project aimed for positive social integration and consensus will be evaluated as model case for social combination apartment in future. And it is necessary to introduce the policies that consider the differences in consciousness and interest of the residents among the lease apartments and common apartments.

• 한국임상약학회지
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• 제9권1호
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• pp.1-14
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• 1999

Vancomycin-resistant Enterococci (VRE) have recently emerged in Korean hospitals, as well as in those of other countries. VRE have been partially attributed to the overuse and misuse of vancomycin. The mecbanisms of VRE resistance are related to VanA, VanB, and VanC. Both VanA and VanB produce abnormal ligase enzymes to form D-ala-D-lactate termini in E. faecium and E. faecalis, instead of D-ala-D-ala termini. Meanwhile, Van C produces D-ser-D-ala termini in E. gallinarum and E. casseliflavus. These abnormal termini have a low affinity to vancomycin. As a result, VRE avoid the activity of vancomycin by these mechanisms. Unfortunately, there is no approved therapy for the treatment of VRE. Thus, available but uncommonly prescribed antibiotics (due to their toxicity or unproven efficacy) may become possible options. They include chloramphenicol, novobiocin, fosfomycin, and bacitracin. The combination therapy of available agents may also be the other options. They include high doses of a penicillin- or ampicillin-aminoglycoside combination, high doses of an ampicillin/sulbactam and aminoglyoosidcs combination, an ampicillin and vancomycin combination, and a ciprofloxacin, aminoglycosides, and rifampin combination. With respect to the near future, many types of investigational agents will most likely expand their treatment options for VRE. Teicoplanin, a glycopeptide, can be used for VanB- and VanC-related VRE. LY333328, a new generation of glycopeptide, is effective in treating VanA as well as VanB and VanC. RP59500 (quinupristin/dalfopristin), a streptogramin, is effective in treating vancomycin-resistant E. faecium. New generation quinolones (especially clinatloxacin) are potential options for the treatment of VRE, even though they cannot work as effectively against VRE as they can against Staphylococci. Both glycylcyclines (a new generation of tetracyclines) and ketolides (a new generation of macrolides) show good activity against Enterococci, regardless of vancomycin susceptibility. Oxazolidinones (i. e. eperezolid and 1inezolid) and everninomicins (i. e. SCH27899) are new groups of antibiotics, which also demonstrate good activity against VRE. It is imperative that clinical pharmacists take the responsibility of investigating new treatment options for VRE in order to combat this growing problem throughout the world.

• 사상체질의학회지
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• 제19권2호
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• pp.1-10
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• 2007

1. Objectives This paper was written in order to understand prescription's combination of Taeumin. 2. Methods We analysis prescription's combination of Taeumin through pathology and new prescription in Sinchukbon(辛丑本) of ${\ulcorner}$Dongyisusebowon${\lrcorner}$. 3. Results and Conclusions New prescription of Taeumin is combined with a few specific prescription. We analysis new prescription of the exterior disease and get the basic prescription that is Chobonkwon Taeummahwang-tang(太陰麻黃湯), Chobonkwon Saengmac-san(生脈散) and Gunyul ${\cdot}$ Euiin ${\cdot}$ Nabokja(乾栗 ${\cdot}$ 薏苡仁). And we analysis new prescription of the interior disease and get the basic prescription that is Jojung-tang(調中湯), Galgunhagi-tang(葛根解肌湯) and Isunggugo-hwan(二聖救苦丸) of old prescription. However, pharmacology of Eumhyulmogal is different from the other symptom and disease. That contain the pharmacology of Chungsimyunja-tang(淸心蓮子湯). We can't find Chungsimyunja-tang from the discussion of symptom and disease. So we can estimate that Chungsimyunja-tang belongs to the prescription of Eumhyulmogal.

• 생물정신의학
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• 제5권2호
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• pp.175-183
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• 1998

To consider current concepts of epilepsy further, the brief review begins with a discussion of what is epilepsy, discribes multifactorial nature of epileptic disorders, and ends with a presentation of current classifications. A combination of the standard antiepielptic drugs(AEDs) may be necessary to treat intractable seizures, but no studies have been done to indicate an optimal combination. The new AEDs provide alternative choices, but questions remain about the optimal timing and manner of administration. AEDs selection must individualized, no drug of choice can be named for all patients.

• 경영과학
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• 제25권3호
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• pp.101-122
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• 2008

A wide variety of convergent digital products are emerging through the combination of multiple independent digital technologies. Digital convergence provides new revenue sources for businesses and new ways of satisfying individual needs of consumers. Despite its business and consumer implications, little research has addressed how people perceive or evaluate convergent products. This study aims at understanding how consumers interpret and evaluate convergent digital products by conducting two consecutive studies. Firstly, a survey was conducted to understand how people interpret convergent products in three ways suggested by the conceptual combination theory based in cognitive science. Secondly, an experiment was conducted to investigate the impact of combination strategies and product similarities on user evaluation of convergent products. Study results indicate that similarity of constituent products has a substantial effect on the interpretation of concept combination strategies. Moreover, combination strategy and product similarity were found to have substantial effects on user comprehension, perceived newness, and preferences for convergent products. This paper ends with an examination of the implications and limitations of the study results.

• Journal of Microbiology and Biotechnology
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• 제28권11호
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• pp.1771-1781
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• 2018

The emergence of multidrug-resistant microorganisms, as well as fungal infectious diseases that further threaten health, especially in immunodeficient populations, is a major global problem. The development of new antifungal agents in clinical trials is inferior to the incidence of drug resistance, and the available antifungal agents are restricted. Their mechanisms aim at certain characteristics of the fungus in order to avoid biological similarities with the host. Synthesis of the cell wall and ergosterol are mainly targeted in clinical use. The need for new approaches to antifungal therapeutic agents or development alternatives has increased. This review explores new perspectives on mechanisms to effectively combat fungal infections and effective antifungal activity. The clinical drug have a common feature that ultimately causes caspase-dependent cell death. The drugs-induced cell death pathway is associated with mitochondrial dysfunction, including mitochondrial membrane depolarization and cytochrome c release. This mechanism of action also reveals antimicrobial peptides, the primary effector molecules of innate systems, to highlight new alternatives. Furthermore, drug combination therapy is suggested as another strategy to combat fungal infection. The proposal for a new approach to antifungal agents is not only important from a basic scientific point of view, but will also assist in the selection of molecules for combination therapy.

• 한국균학회지
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• 제27권2호통권89호
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• pp.175-179
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• 1999

잔나비걸상 Elfvingia applananta 자실체의 수용성물질 EA의 vesicular stomatitis virus[New Jersey serotype, VSV(NJ)]에 대한 항바이러스효과를 plaque reduction assay에 따라 실험한 결과 EA는 용량의존적으로 plaque 형성을 억제하였으며 $EC_{50}$는 2.10 mg/ml이었다. 단백질성 항바이러스제인 interferon(IFN)과 EA와의 병용시험 결과 f(a)가 0.50에서 0.90인 유효농도범위에서 IFN alpha와 병용시 f(a)의 값이 커짐에 따라 상가작용 내지는 길항작용을 나타내었으며, IFN gamma와의 병용시에는 길항작용을 나타내었다. 따라서 IFN alpha와의 병용시 f(a)가 0.50내지 0.70의 유효농도 범위에서 상가효과가 있다.

• Management Science and Financial Engineering
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• 제9권1호
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• pp.4-10
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• 2003

We introduce a new estimator of the uncertainty of a jackknife estimate of standard error: the jack-knife-after-jackknife (JAJ). Using Monte Carlo simulation, we assess the accuracy of the JAJ in a variety of settings defined by statistic of interest, data distribution, and sample size. For comparison, we also assess the accuracy of the jackknife-after-bootstrap (JAB) estimate of the uncertainty of a bootstrap standard error. We conclude that the JAJ provides a useful new supplement to Tukey's jackknife, and the combination of jackknife and JAJ provides a useful alternative to the combination of bootstrap and JAB.