• The Korean Journal of Physiology and Pharmacology
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• 제1권2호
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• pp.185-193
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• 1997

The characteristics of $Na^+$-dependent cycloleucine uptake was investigated in OK cells with regard to substrate specificity and regulation by protein kinase C (PKC). Inhibition studies with different synthetic and natural amino acids showed a broad spectrum affinity to neutral amino acids regardless of their different side chains including branched or aromatic, indicating that the $Na^+$-dependent cycloleucine uptake in OK cells is mediated by System $B^o$ or System $B^o$-like transporter rather than the classical System A or ASC. Phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate, but not $4{\alpha}-PMA$ elicited a time-dependent biphasic stimulation of $Na^+$-dependent cycloleucine uptake, which produced early transient peak at 30 min and late sustained peak at 180min. Both the early and late stimulations by PMA were due to an increase in Vmax and not due to a change in Km. PKC inhibitors blocked both the early and late stimulation by PMA, while protein synthesis inhibitors blocked the late stimulation only. These results suggest the existence and regulation by PKC of System $B^o$ or System $B^o$-like broad spectrum transport system for neutral amino acids in OK cells.

• Archives of Pharmacal Research
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• 제13권4호
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• pp.330-337
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• 1990

The crude polysaccharide from Panax ginseng prepared by hot water extration and precipiation with ethanol was further fractionated into neutral and acidic fractions by DEAE- cellulose ion exchange chromatography. The chemical compositions were 85.0% carbohydrorate and 15.0% protein for the neutral fraction, and 28.4% carbohydrate, 10.0% protein and 29.0% uronic acid for the acidic fraction. The acidic fraction was more effective in increasing of the ratio of spleen to body weight, the number of antibody secreting cells to SRBC and phagocytic activity of reticuloendothelial system, as well as antitumor activity against the solid form of sarcoma 180 in ICR mice than the neutral fraction. All polysaccharide fractions were mitogenic to cultured spleen cells of C57BL/6 mice. However, FA was different from FN in the co-mitogenicities with lectin mitogens. Both crude and acidic fractions potentiated remarkably the mitogenic activity of PHA-P or LPS in dose-dependent manner but neutral fraction enhanced only that of LPS. Three polysaccharide fractions had no effect on that of Con A. These results suggest that the acidic fraction may stimulate B and Td cells as well as macrophages while the neutral fraction may simulate only B cells and macropages.

• Journal of Korean Dental Science
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• 제2권2호
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• pp.5-11
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• 2009

Objectives : This study investigated the hypothesis that the dentin bond strength of self-etching adhesives (SEAs) may be improved by applying a coat of hydrophobic, neutral adhesive resin in addition to SEA. Method and Materials : The bond strengths of two SEAs - Experimental SEA (EX) and Adper Prompt (AP) - were measured with three bonding protocols. The D/E resin of All-Bond 2 was applied as the hydrophobic, neutral adhesive. Clearfil SE Bond (SE, self-etching primer system) and All-Bond 2 (AB, total etching system) were used as references. The following protocols were used: (1) EX1 (EX 1 coat); (2) EX2 (EX 2 coats); (3) EX+ (EX 1 coat + D/E resin); (4) AP1 (AP 1 coat); (5) AP2 (AP 2 coats); (6) AP+ (AP 1 coat + D/E resin); (7) SE (SE primer + SE bond); (8) SE+ (SE primer + D/E resin); (9) AB (etching + AB primer + D/E resin). Filtek Z250 composite resin was built up and the microtensile bond strength (MTBS) values of the specimens were compared. The fractured surfaces were observed using SEM. Results : When SEA was used as self-etching primer and hydrophobic, neutral adhesive was applied as well, MTBS was significantly higher than that when either one coat or two coats of SEA only were used (p < 0.05). Conclusion : The hydrophobic, neutral adhesive improved the integrity of the bonded interface obtained with SEA.

• 한국지능시스템학회논문지
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• 제18권2호
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• pp.151-156
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• 2008

본 논문은 뉴트럴 타입 시간 지연을 가지는 네트워크 기반 시스템의 안정도 분석 및 샘플치 퍼지 제어기 설계 방법에 관하여 논의한다. 먼저 대상이 되는 비선형 네트워크 시스템을 T-S (Takagi-Sugeno) 퍼지 모델로 표현한다. 제안하는 샘플치 퍼지 제어기를 모델링하는 퍼지 규칙과 같은 멤버쉽 함수를 가지게 설계한다. Lyapunov-Krasovskii의 안정화 이론을 도입하여 이를 바탕으로 뉴트럴 형태의 시간 지연을 갖는 T-S 퍼지 시스템의 안정도를 판별한다. T-S 퍼지 시스템의 안정도 조건을 제시하고 선형 행렬 부등식의 형태로 표현한다. 제안된 선형 행렬 부등식의 해를 통하여 샘플치 퍼지 제어기의 이득 값을 설계한다. 마지막으로, 본 논문에서 제안한 방법의 적용 가능성과 일반성을 평가하기 위하여 수치적인 예를 적용한다.

• 인지과학
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• 제21권2호
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• pp.387-408
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• 2010

이 연구는 자극의 정서성에 따른 부호화 기전의 차이와 맥락의 정서성이 중립 단어의 부호화 기전에 미치는 영향을 알아보기 위해 수행되었으며, 특히 정서자극의 우수한 기억 수행이 주의자원 배분에 기인한 것인지 밝히는 것을 목적으로 하였다. 이 연구는 연구 목적을 달성하기 위해 정서자극과 비정서적 단어를 연속으로 제시하여 자극과 맥락의 정서성이 기억 수행과 ERP 평균 진폭에 미치는 영향을 분석하였다. 정서자극으로는 IAPS(International Affective Picture System) 자극을 사용하였으며, 긍정, 중립, 부정자극을 제시하였다. 행동 분석결과, 정서자극이 중립자극보다 우수한 기억 수행을 보인 반면, 정서맥락 내 단어는 중립맥락 내 단어에 비해 저조한 기억 수행을 보였다. 또한 ERP의 LPC(Late Positive Complex) 진폭분석 결과, 정서자극이 중립자극에 비해 높은 진폭을 보인 반면, 정서맥락 내 단어는 중립맥락 내 단어에 비해 낮은 진폭을 나타냈다. 이 결과는 정서자극에 대한 주의 선점이 정서맥락 내 단어의 기억 수행을 방해한다는 자원할당 모형의 설명에 부합하는 것으로서, 정서자극에 대한 주의자원 배분 설명을 지지하는 것이다.

• Advances in concrete construction
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• 제14권2호
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• pp.79-92
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• 2022

The amount and configuration of transverse reinforcement are known as critical parameters that significantly affect the lateral confinement of concrete, the ductility capacity, and the plastic hinge length of RC columns. Based on test results, this study investigated the effect of the three variables on structural indexes such as neutral axis depth, lateral expansion of concrete, and ductility capacity. Five reinforced concrete column specimens were tested under cyclic flexure and shear while simultaneously subjected to a constant axial load. The columns were reinforced by two types of reinforcing steel: rectangular hoops and spiral type reinforcing bars. The variables in the test program were the shape, diameter, and yield strength of transverse reinforcement. The interactive influence of the amount of transverse reinforcement on the structural indexes was evaluated. Test results showed that when amounts of transverse reinforcement were similar, and yield strength of transverse reinforcement was 600 MPa or less, the neutral axis depth of a column with spiral type reinforcing bars was reduced by 28% compared with that of a column reinforced by existing rectangular hoops at peak strength. While the diagonal elements of spiral-type reinforcing bars significantly contributed to the lateral confinement of concrete, the strain of diagonal elements decreased with increases of their yield strength. It was confirmed that shapes of transverse reinforcement significantly affected the lateral confinement of concrete adjacent to plastic hinges. Transverse reinforcement with a yield strength exceeding 600 MPa, however, increased the neutral axis depth of normal-strength concrete columns at peak strength, resulting in reductions in ductility and energy dissipation capacity.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 추계학술대회 논문집 학회본부A
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• pp.131-133
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• 1998

This paper, proposed the p-q-r coordinate system where the instantaneous active power p, and the two instantaneous reactive powers $q_{q}$, $q_{r}$ were defined. The three power components are linearly independent, so the compensation for the two instantaneous reactive powers leads to control the two components of the current space vector. With the theory, the neutral current of the three-phase four-wire system can be eliminated by only compensating the instantaneous reactive power using no energy storage element.

• Kyungpook Mathematical Journal
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• 제48권1호
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• pp.1-14
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• 2008

In this paper, we investigate the existence of solutions of second order impulsive neutral functional differential inclusions which the nonlinearity F admits convex and non-convex values. Some results under weaker conditions are presented. Our results extend previous ones. The methods rely on a fixed point theorem for condensing multivalued maps and Schaefer's fixed point theorem combined with lower semi-continuous multivalued operators with decomposable values.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1990년도 추계학술대회 논문집 학회본부
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• pp.210-213
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• 1990

This paper presents the countermeasure to present the main transformer of distribution substation from deteriorating and failing due to repeated magnetic force of the transformer winding by ground fault current in 22.9kV multi grounded distribution system. The Winding strength to the short circuit current is designed to be endurable to the stress of over current. But this design is related to the manufactures. In this paper we examine the application of shunt reactor to the neutral point of the low side of the transformer to reduce fault current due to the fault in the distribution lines we have analysed the fault characteristics of the system and calculated the optimum ohmic values of the neutral reactor.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 추계학술대회 논문집 전력기술부문
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• pp.103-106
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• 2008

OPNW, which takes charge of the outer neutral wire role and the inner optical network role, was developed at the first time among nation and substituted the neutral wire of distribution line between electric power substation and neighboring station. This paper refers to results about its optical character measured periodically, and examines closely whether the unique matter will be occurred or not about the role of neutral wire during more than one year. Also, established OPNW became a new chance to distribution facility's working by establishing remote portrait supervisory system and doing remote supervisory about essential equipment of distribution line.