• Title/Summary/Keyword: Network and Risk Index

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Preoperative neutrophil-to-lymphocyte ratio is prognostic for early recurrence after curative intrahepatic cholangiocarcinoma resection

  • Woo Jin Choi;Fiorella Murillo Perez;Annabel Gravely;Tommy Ivanics;Marco P. A. W. Claasen;Liza Abraham;Phillipe Abreu;Robin Visser;Steven Gallinger;Bettina E. Hansen;Gonzalo Sapisochin
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.2
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    • pp.158-165
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    • 2023
  • Backgrounds/Aims: Within two years of surgery, 70% of resected intrahepatic cholangiocarcinoma (iCCA) recur. Better biomarkers are needed to identify those at risk of "early recurrence" (ER). In this study, we defined ER and investigated whether preoperative neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic-inflammatory index were prognostic of both overall relapse and ER after curative hepatectomy for iCCA. Methods: A retrospective cohort of patients who underwent curative-intent hepatectomy for iCCA between 2005 and 2017 were created. The cut-off timepoint for the ER of iCCA was estimated using a piecewise linear regression model. Univariable analyses of recurrence were conducted for the overall, early, and late recurrence periods. For the early and late recurrence periods, multivariable Cox regression with time-varying regression coefficient analysis was used. Results: A total of 113 patients were included in this study. ER was defined as recurrence within 12 months of a curative resection. Among the included patients, 38.1% experienced ER. In the univariable model, a higher preoperative NLR (> 4.3) was significantly associated with an increased risk of recurrence overall and in the first 12 months after curative surgery. In the multivariable model, a higher NLR was associated with a higher recurrence rate overall and in the ER period (≤ 12 months), but not in the late recurrence period. Conclusions: Preoperative NLR was prognostic of both overall recurrence and ER after curative iCCA resection. NLR is easily obtained before and after surgery and should be integrated into ER prediction tools to guide preoperative treatments and intensify postoperative follow-up.

The Mitigation Model Development for Minimizing IT Operational Risks (IT운영리스크 최소화를 위한 피해저감모델 구현에 관한 연구)

  • Lee, Young-Jai;Hwang, Myung-Soo
    • Journal of Information Technology Applications and Management
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    • v.14 no.3
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    • pp.95-113
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    • 2007
  • To minimize IT operational risks and the opportunity cost for lost business hours. it is necessary to have preparedness in advance and mitigation activities for minimization of a loss due to the business discontinuity. There are few cases that banks have a policy on systematic management, system recovery and protection activities against system failure. and most developers and system administrators response based on their experience and the instinct. This article focuses on the mitigation model development for minimizing the incidents of disk unit in IT operational risks. The model will be represented by a network model which is composed of the three items as following: (1) the risk factors(causes, attributes and indicators) of IT operational risk. (2) a periodic time interval through an analysis of historical data. (3) an index or an operational regulations related to the examination of causes of an operational risk. This article will be helpful when enterprise needs to hierarchically analyze risk factors from various fields of IT(information security, information telecommunication, web application servers and so on) and develop a mitigation model. and it will also contribute to the reduction of operational risks on information systems.

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Development of Computation Model for Traffic Accidents Risk Index - Focusing on Intersection in Chuncheon City - (교통사고 위험도 지수 산정 모델 개발 - 춘천시 교차로를 중심으로 -)

  • Shim, Kywan-Bho;Hwang, Kyung-Soo
    • International Journal of Highway Engineering
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    • v.11 no.3
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    • pp.61-74
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    • 2009
  • Traffic accident risk index Computation model's development apply traffic level of significance about area of road user group, road and street network area, population group etc.. through numerical formula or model by countermeasure to reduce the occurrence rate of traffic accidents. Is real condition that is taking advantage of risk by tangent section through estimation model and by method to choose improvement way to intersection from outside the country, and is utilizing being applied in part business in domestic. However, question is brought in the accuracy being utilizing changing some to take external model in domestic real condition than individual development of model. Therefore, selection intersection estimation element through traffic accidents occurrence present condition, geometry structure, control way, traffic volume, turning traffic volume etc. in 96 intersections in this research, and select final variable through correlation analysis of abstracted estimation elements. Developed intersection design model taking advantage of signal type, numeric of lane, intersection type, analysis of variance techniques through ANOVA analysis of three variables of intersection form with selected variable lastly, in signal crossing through three class intersection, distinction variable choice risk in model, no-signal crossing risk distinction analysis model and so on develop.

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A Comparative Study of Prediction Models for College Student Dropout Risk Using Machine Learning: Focusing on the case of N university (머신러닝을 활용한 대학생 중도탈락 위험군의 예측모델 비교 연구 : N대학 사례를 중심으로)

  • So-Hyun Kim;Sung-Hyoun Cho
    • Journal of The Korean Society of Integrative Medicine
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    • v.12 no.2
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    • pp.155-166
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    • 2024
  • Purpose : This study aims to identify key factors for predicting dropout risk at the university level and to provide a foundation for policy development aimed at dropout prevention. This study explores the optimal machine learning algorithm by comparing the performance of various algorithms using data on college students' dropout risks. Methods : We collected data on factors influencing dropout risk and propensity were collected from N University. The collected data were applied to several machine learning algorithms, including random forest, decision tree, artificial neural network, logistic regression, support vector machine (SVM), k-nearest neighbor (k-NN) classification, and Naive Bayes. The performance of these models was compared and evaluated, with a focus on predictive validity and the identification of significant dropout factors through the information gain index of machine learning. Results : The binary logistic regression analysis showed that the year of the program, department, grades, and year of entry had a statistically significant effect on the dropout risk. The performance of each machine learning algorithm showed that random forest performed the best. The results showed that the relative importance of the predictor variables was highest for department, age, grade, and residence, in the order of whether or not they matched the school location. Conclusion : Machine learning-based prediction of dropout risk focuses on the early identification of students at risk. The types and causes of dropout crises vary significantly among students. It is important to identify the types and causes of dropout crises so that appropriate actions and support can be taken to remove risk factors and increase protective factors. The relative importance of the factors affecting dropout risk found in this study will help guide educational prescriptions for preventing college student dropout.

Research trends related to childhood and adolescent cancer survivors in South Korea using word co-occurrence network analysis

  • Kang, Kyung-Ah;Han, Suk Jung;Chun, Jiyoung;Kim, Hyun-Yong
    • Child Health Nursing Research
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    • v.27 no.3
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    • pp.201-210
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    • 2021
  • Purpose: This study analyzed research trends related to childhood and adolescent cancer survivors (CACS) using word co-occurrence network analysis on studies registered in the Korean Citation Index (KCI). Methods: This word co-occurrence network analysis study explored major research trends by constructing a network based on relationships between keywords (semantic morphemes) in the abstracts of published articles. Research articles published in the KCI over the past 10 years were collected using the Biblio Data Collector tool included in the NetMiner Program (version 4), using "cancer survivors", "adolescent", and "child" as the main search terms. After pre-processing, analyses were conducted on centrality (degree and eigenvector), cohesion (community), and topic modeling. Results: For centrality, the top 10 keywords included "treatment", "factor", "intervention", "group", "radiotherapy", "health", "risk", "measurement", "outcome", and "quality of life". In terms of cohesion and topic analysis, three categories were identified as the major research trends: "treatment and complications", "adaptation and support needs", and "management and quality of life". Conclusion: The keywords from the three main categories reflected interdisciplinary identification. Many studies on adaptation and support needs were identified in our analysis of nursing literature. Further research on managing and evaluating the quality of life among CACS must also be conducted.

Forecasting volatility index by temporal convolutional neural network (Causal temporal convolutional neural network를 이용한 변동성 지수 예측)

  • Ji Won Shin;Dong Wan Shin
    • The Korean Journal of Applied Statistics
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    • v.36 no.2
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    • pp.129-139
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    • 2023
  • Forecasting volatility is essential to avoiding the risk caused by the uncertainties of an financial asset. Complicated financial volatility features such as ambiguity between non-stationarity and stationarity, asymmetry, long-memory, sudden fairly large values like outliers bring great challenges to volatility forecasts. In order to address such complicated features implicity, we consider machine leaning models such as LSTM (1997) and GRU (2014), which are known to be suitable for existing time series forecasting. However, there are the problems of vanishing gradients, of enormous amount of computation, and of a huge memory. To solve these problems, a causal temporal convolutional network (TCN) model, an advanced form of 1D CNN, is also applied. It is confirmed that the overall forecasting power of TCN model is higher than that of the RNN models in forecasting VIX, VXD, and VXN, the daily volatility indices of S&P 500, DJIA, Nasdaq, respectively.

Refining and Validating a Two-stage and Web-based Cancer Risk Assessment Tool for Village Doctors in China

  • Shen, Xing-Rong;Chai, Jing;Feng, Rui;Liu, Tong-Zhu;Tong, Gui-Xian;Cheng, Jing;Li, Kai-Chun;Xie, Shao-Yu;Shi, Yong;Wang, De-Bin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10683-10690
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    • 2015
  • The big gap between efficacy of population level prevention and expectations due to heterogeneity and complexity of cancer etiologic factors calls for selective yet personalized interventions based on effective risk assessment. This paper documents our research protocol aimed at refining and validating a two-stage and web-based cancer risk assessment tool, from a tentative one in use by an ongoing project, capable of identifying individuals at elevated risk for one or more types of the 80% leading cancers in rural China with adequate sensitivity and specificity and featuring low cost, easy application and cultural and technical sensitivity for farmers and village doctors. The protocol adopted a modified population-based case control design using 72, 000 non-patients as controls, 2, 200 cancer patients as cases, and another 600 patients as cases for external validation. Factors taken into account comprised 8 domains including diet and nutrition, risk behaviors, family history, precancerous diseases, related medical procedures, exposure to environment hazards, mood and feelings, physical activities and anthropologic and biologic factors. Modeling stresses explored various methodologies like empirical analysis, logistic regression, neuro-network analysis, decision theory and both internal and external validation using concordance statistics, predictive values, etc..

Shanghai Containerised Freight Index Forecasting Based on Deep Learning Methods: Evidence from Chinese Futures Markets

  • Liang Chen;Jiankun Li;Rongyu Pei;Zhenqing Su;Ziyang Liu
    • East Asian Economic Review
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    • v.28 no.3
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    • pp.359-388
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    • 2024
  • With the escalation of global trade, the Chinese commodity futures market has ascended to a pivotal role within the international shipping landscape. The Shanghai Containerized Freight Index (SCFI), a leading indicator of the shipping industry's health, is particularly sensitive to the vicissitudes of the Chinese commodity futures sector. Nevertheless, a significant research gap exists regarding the application of Chinese commodity futures prices as predictive tools for the SCFI. To address this gap, the present study employs a comprehensive dataset spanning daily observations from March 24, 2017, to May 27, 2022, encompassing a total of 29,308 data points. We have crafted an innovative deep learning model that synergistically combines Long Short-Term Memory (LSTM) and Convolutional Neural Network (CNN) architectures. The outcomes show that the CNN-LSTM model does a great job of finding the nonlinear dynamics in the SCFI dataset and accurately capturing its long-term temporal dependencies. The model can handle changes in random sample selection, data frequency, and structural shifts within the dataset. It achieved an impressive R2 of 96.6% and did better than the LSTM and CNN models that were used alone. This research underscores the predictive prowess of the Chinese futures market in influencing the Shipping Cost Index, deepening our understanding of the intricate relationship between the shipping industry and the financial sphere. Furthermore, it broadens the scope of machine learning applications in maritime transportation management, paving the way for SCFI forecasting research. The study's findings offer potent decision-support tools and risk management solutions for logistics enterprises, shipping corporations, and governmental entities.

Drought risk assessment considering regional socio-economic factors and water supply system (지역의 사회·경제적 인자와 용수공급체계를 고려한 가뭄 위험도 평가)

  • Kim, Ji Eun;Kim, Min Ji;Choi, Sijung;Lee, Joo-Heon;Kim, Tae-Woong
    • Journal of Korea Water Resources Association
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    • v.55 no.8
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    • pp.589-601
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    • 2022
  • Although drought is a natural phenomenon, its damage occurs in combination with regional physical and social factors. Especially, related to the supply and demand of various waters, drought causes great socio-economic damage. Even meteorological droughts occur with similar severity, its impact varies depending on the regional characteristics and water supply system. Therefore, this study assessed regional drought risk considering regional socio-economic factors and water supply system. Drought hazard was assessed by grading the joint drought management index (JDMI) which represents water shortage. Drought vulnerability was assessed by weighted averaging 10 socio-economic factors using Entropy, Principal Component Analysis (PCA), and Gaussian Mixture Model (GMM). Drought response capacity that represents regional water supply factors was assessed by employing Bayesian networks. Drought risk was determined by multiplying a cubic root of the hazard, vulnerability, and response capacity. For the drought hazard meaning the possibility of failure to supply water, Goesan-gun was the highest at 0.81. For the drought vulnerability, Daejeon was most vulnerable at 0.61. Considering the regional water supply system, Sejong had the lowest drought response capacity. Finally, the drought risk was the highest in Cheongju-si. This study identified the regional drought risk and vulnerable causes of drought, which is useful in preparing drought mitigation policy considering the regional characteristics in the future.

Study on Neuron Activities for Adversarial Examples in Convolutional Neural Network Model by Population Sparseness Index (개체군 희소성 인덱스에 의한 컨벌루션 신경망 모델의 적대적 예제에 대한 뉴런 활동에 관한 연구)

  • Youngseok Lee
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.16 no.1
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    • pp.1-7
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    • 2023
  • Convolutional neural networks have already been applied to various fields beyond human visual processing capabilities in the image processing area. However, they are exposed to a severe risk of deteriorating model performance due to the appearance of adversarial attacks. In addition, defense technology to respond to adversarial attacks is effective against the attack but is vulnerable to other types of attacks. Therefore, to respond to an adversarial attack, it is necessary to analyze how the performance of the adversarial attack deteriorates through the process inside the convolutional neural network. In this study, the adversarial attack of the Alexnet and VGG11 models was analyzed using the population sparseness index, a measure of neuronal activity in neurophysiology. Through the research, it was observed in each layer that the population sparsity index for adversarial examples showed differences from that of benign examples.