• 한국동물학회지
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• 제38권3호
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• pp.433-441
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• 1995

염소 베타-락토글로불린 유전자 프로모터의 유선 조직 특이성은, 비 발현 세포에서 -470 에서 -205 부위에 의해서 매개되는 억제 조절에 의해서 보증된다. 이 음성 조절 기작과 억제 조절을 매개하는 인자를 확인하기 위하여 상류 염기 서열을 자세히 분석하였다. 상류 염기 서열은 어느 방향으로 위치하든 연결된 베타-락토글로불린 유전자 프로모터의 활성을 억제할 수 있었다. 이와 같이 규명된 염소 베타-락토글로불린 유전자의 잠정적 음성 조절 인자는 다른 유전자의 프로모터들에 대해서는 다양한 활성을 보였는데, herpes simplex 바이러스의 thimidine kinase 프로모터는 상류 염기서열의 방향에 따라 억제 또는 활성화되었으며, SV40 프로모터는 억제되기보다는 오히려 활성화되었다. 염소 베타-락토글로불린 유전자의 억제 조절 인자를 포함하는 조절 부위는 비 유선 세포인 HeLa 및 CV-1 세포에서 추출된 핵 추출물에 의해서 이동성이 강력하게 지연되는 반면, 유선세포인 HC11 세포의 핵 추출물에 의해서는 약하게 지연되었다. 이와 같은 활성 억제와 인자 결합간의 연관성은 foot-printing 분석에서 관찰된 결합 부위가 염소의 베타-락토글로불린 유전자의 조직특이적 억제에 작용할 음성 조절 인자일 가능성을 시사한다.

• 한국직업건강간호학회지
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• 제6권2호
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• pp.128-135
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• 1997

This study was carried out to describe the relationship between food habit and gastric symptom. Five hundreds ten women working more than 6 months were chosen for samples among the residents in Seoul and Kyungki provinces. This survey was done by questionnaire from the 5th September to the 5th October 1996. The results was followed : 1. The average score of the food habit in the career women was 9.6 among the total score. 20 2. The food habit of the career women appeared worse to whom were younger, single, and having loss educational backgrounded and living apart from family, When the average score of food habit was compared between groups, nurses group was lower than the other group, and shift workers. 3. The average score of gastric symptom was 8.1 among the total score 30. 4. The average gastric symptom score of the career women was resulted in less high among the younger, single, technical college graduated and living separately from the family. In the group comparison, the nurse group showed higher score than teachers and shift worker group showed higher score than nonshift worker. 5. There were negative correlation between food habit and gastric symptom. From the research point of view, the food habit of career women resulted differently depending on their occupations and invidual characteristics. Therefore, education and guidence for appropriate ate diet and food habit will be considered as necessary for health of the working women.

• 한국직업건강간호학회지
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• 제20권2호
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• pp.130-142
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• 2011

Purpose: The purpose of this study was to identify the relationships among emotional labor, empowerment, job burnout, and turnover intention. Methods: The design of this study was a cross-sectional descriptive study. The subjects of this study were 358 nurses working for over 6 months in Seoul and Gyeonggi-do. The data were collected from 4th to 30th of September, 2009 through one-to-one interviews. Survey data were analyzed using t-test, one-way ANOVA, Pearson's correlation coefficient, and hierarchical regression. Results: We find the positive correlation of turnover intention with emotional labor and with job burnout, but the negative correlation of empowerment with job burnout and with turnover intention. The nurses' turnover intention scores were relatively low with 1.30. Job burnout, shift work, and frequency of turnover were predictors of turnover intention. The most powerful predictor variable was job burnout (${\beta}$=.420, p<.001). We find that emotional labor and empowerment as determinants of turnover intention are not significant. Conclusion: These results suggest that manager should consider shift work of nurses and job burnout in order to manage nurse organization and resource effectively.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
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• pp.1701-1703
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• 2006

Here we describe a novel driving scheme in the form of negative AC bias stress (NAC) to compensate shift in the threshold voltage for hydrogenated amorphous silicon (${\alpha}$-Si:H) thin film transistor (TFT) for AMOLED applications. This scheme preserves the threshold voltage shift of ${\alpha}$-Si:H TFT for infinitely long duration of time(>30,000 hours) and thereby overall performance, without using any additional TFTs for compensation. We briefly describe about the possible driving schemes in order to implement for real time AMOLED applications. We attribute most of the results based on concept of plugging holes and electrons across the interface of the gate insulator in a controlled manner.

• 한국도로학회논문집
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• 제15권4호
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• pp.135-146
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• 2013

PURPOSES : This study aimed to analyze the impact the operation of pre-signals at 4-leg signalized intersections and present primary environmental factors of roads that need to be considered in the installation of pre-signals. METHODS : Shift of proportions safety effectiveness evaluation method which assesses shifts in proportions of target collision types to determine safety effectiveness was applied to analyze traffic crash by types. Also, Empirical Bayes before/after safety effectiveness evaluation method was adapted to analyze the impact pre-signal installation. Negative binomial regression was conducted to determine SPF(safety performance function). RESULTS : Pre-signals are effective in reducing the number of head on, right angle and sideswipe collisions and both the total number of personal injury crashes and severe crashes. Also, it is deemed that each factor used as an independent variable for the SPF model has strong correlation with the total number of personal injury crashes and severe crashes, and impacts general traffic crashes as a whole. CONCLUSIONS: This study suggests the following should be considered in pre-signal installation on intersections. 1) U-turns allowed in the front and rear 2) A high number of roads that connect to the intersection 3) Many right-turn traffic flows 4) Crosswalks installed in the front and rear 5) Insufficient left-turn lanes compared to left-turn traffic flows or no left-turn-only lane.

• 대한화학회지
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• 제40권12호
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• pp.741-747
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• 1996

기능성색소로 응용되는 몇몇 squarylium 및 croconium계 색소를 합성한 후 이들이 특성에 관해 조사했다. Squarylium 색소의 경우 5위치에 니트로기의 도입에 의하여 대폭 심색이동이 관찰되었으며 IR 및 solvatochromism 특성으로부터 중심 4고리의 1, 3 위치에 indoline환이 결합된 형태이며 기저상태가 극성인 구조를 취하고 있음을 알 수 있었다. 또한 다단계반응에 의해 비대칭 squaryliunm계 색소를 합성하였다. 중심에 5고리를 가지는 croconium계 색소를 합성하였으며 이들은 770-780nm에 ${\lambda}_{max}$을 나타냈다. 이들 색소의 구조와 흡수스펙트럼의 관계를 PPP-MO를 상용하여 해석한 결과 실측치와 좋은 상관관계를 나타냈다.

• 한국전자통신학회논문지
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• 제13권6호
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• pp.1177-1182
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• 2018

UCC3895 드라이버를 이용하여 위상천이방식의 100Mhz로 운용되는 500W급 영전압스위칭(Zero voltage switching) DC/DC 컨버터를 설계하였다. UCC3895 드라이버의 데드타임은 풀브리지의 리딩래그와 레깅래그가 별도로 구동 가능하도록 설계되어 있어 두 래그간에 데드타임을 별도로 부여하는 것이 가능하며, 이것은 두 래그간에 비대칭관계인 데드타임으로 영전압스위칭의 구현을 가능하게 하였다. 또한 본 논문에서는 안정된 출력전압을 위한 부귀환회로 설계방식이 제안되었다. 시제품의 최대 효율은 $500{\Omega}$의 부하에서 95.5% 정도를 나타냈다.

• 한국의료질향상학회지
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• 제27권1호
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• pp.2-9
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• 2021

Patient safety remains one of the most important health care issues in Korea. To improve patient safety, we have introduced concepts from the field of safety science such as the Swiss cheese model, and adopted several methodologies previously used in other industries, including incident reporting systems, root cause analysis, and failure mode and effects analysis. This approach has enabled substantial progress in patient safety to be made through undertaking patient safety improvement activities in hospitals that are systems-based, rather than individual-based. However, these methods have the shared limitation of focusing on negative consequences of patient safety. Therefore, the paradigm shift from Safety I to Safety-II in safety science becomes the focus of our discussion. We believe that Safety-II will complement, rather than replace, Safety-I in the discipline of patient safety. In order to continuously advance patient safety practices in Korea, it is necessary that Korea keeps abreast of the recent global trends and development in safety science. In addition, more focus should be placed on testing the feasibility of new patient safety approaches in real-world situations.

• Journal of Ecology and Environment
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• 제35권1호
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• pp.15-25
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• 2012

Time series of ocean climate indices and catch records were used to identify the alternation patterns of pelagic fish populations in relation to climate regime shifts. During 1910-2008, an orderly alternation of dominant pelagic fish groups was observed in the Tsushima Warm Current (TWC; Yellow Sea-East China Sea-East Sea/Japan Sea) and Kuroshio-Oyashio Current (KOC; Northwestern Pacific) regions. After the collapse of herring fishery in the late 1920s, the sardine (A group) dominated in the 1930s, 3 other species (C group; Pacific saury, jack mackerel, and anchovy) dominated in the 1950s-1960s, chub mackerel (B group) dominated in the 1970s, and then sardine (A group) dominated again during cool regime in the 1980s. As sardine biomass decreased in association with the climate regime shift that occurred in the late 1980s, catches of C group immediately increased after the regime shift and remained at high levels during warm regime in the 1990s. Alternations of dominant fish groups occurred 6 times between 1910 and 2008. The dominant period of the 7 species lasted for 10-20 years. The catch of Pacific sardine in the TWC and KOC regions showed a negative correlation with the catch of the other 5 species (Pacific herring, anchovy, jack mackerel, Pacific saury, and common squid), suggesting that the abundance of the 5 species is strongly affected by the abundance of Pacific sardine in relation to the climate regime shifts. The total catch level of the 7 species in the KOC region was generally higher than that in the TWC region before 1991 but was lower after 1992, suggesting that the fish populations in the Pacific side are shifted to the TWC region by zonal oscillation of the oceanic conditions in relation to the climate regime shift in the late 1980s.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2010년도 추계학술대회 초록집
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• pp.111.1-111.1
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• 2010

This paper focuses on a systematic configuration of steam reforming fuel processor, particularly designed for small and medium sized hydrogen production application. In a typical integration of the fuel processor, there exist significant temperature gradients over the entire system which has negative effect on both catalyst life-time and system performance. Also, the volumetric inefficiency should be avoided to obtain the possible compactness for the commercial purpose. In the present work, the computational analysis will be performed to gain the fundamental insight on the transport phenomena and chemical reactions in the reformer consisting of preheating, steam reforming (SR), and water gas shift (WGS) reaction beds in the flow direction. Also, the fuel processing system includes a top-fired burner providing necessary thermal energy for endothermic catalytic reactor. A fully two-dimensional numerical modeling for a integrated fuel processing system is introduced for in-depth analysis of the heat and mass transport phenomena based on surface kinetics and catalytic process. In the model, water gas shift reaction and decomposition reaction were assumed to be at equilibrium. A kinetic model was developed and then computational results were compared with the experimental data available in the literature. Finally, the case study was done by considering the key parameters, i.e. steam to carbon (S/C) ratio and temperature. The computer-aided models developed in this study can be greatly utilized for the design of advanced fast-paced compact fuel processors research.