• Journal of Korea Multimedia Society
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• v.15 no.9
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• pp.1075-1085
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• 2012

In clinical research using medical images, the image segmentation is one of the most important processes. Especially, the hippocampal atrophy is helpful for the clinical Alzheimer diagnosis as a specific marker of the progress of Alzheimer. In order to measure hippocampus volume exactly, segmentation of the hippocampus is essential. However, the hippocampus has some features like relatively low contrast, low signal-to-noise ratio, discreted boundary in MRI images, and these features make it difficult to segment hippocampus. To solve this problem, firstly, We selected region of interest from an experiment image, subtracted a original image from the negative image of the original image, enhanced contrast, and applied anisotropic diffusion filtering and gaussian filtering as preprocessing. Finally, We performed an image segmentation using two level set methods. Through a variety of approaches for the validation of proposed hippocampus segmentation method, We confirmed that our proposed method improved the rate and accuracy of the segmentation. Consequently, the proposed method is suitable for segmentation of the area which has similar features with the hippocampus. We believe that our method has great potential if successfully combined with other research findings.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.2
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• pp.97-103
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• 2015

Until recently, the three conventional evaluation methods, which are instrumental (Chromameter$^{(R)}$ CR-400 and Mexameter$^{(R)}$ M18) and visual assessments have been used frequently for skin color evaluation. However, we took notice the potential of image analysis as a new tool to evaluate color change of skin. To reveal the reliability of the image analysis for the evaluation of whitening agents, 34 healthy female volunteers with hyperpigmentation were recruited, and the selected volunteers applied the whitening products containing Vitamin C twice a day in the morning and evening and received iontophoresis treatments once a week for 8 weeks. The changes in hyperpigmentation evaluated by Chromameter$^{(R)}$, Mexameter$^{(R)}$ and visual assessment were compared with the results from the image analysis. As with $L^*$ value trends of the analysis using Chromameter$^{(R)}$, the V value from the image analysis increased after applying the test products compared with baseline values. Furthermore, V value showed a positive correlation with $L^*$ value (r = 0.494, p < 0.01) and negative correlation with MI (r = - 0.683, p < 0.01) and VG (r = - 0.549, p < 0.01). Therefore, image analysis may be considered as an effective method to complement the limitations of visual assessment for whitening efficacy in Asians.

• Journal of Korean Foot and Ankle Society
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• v.19 no.4
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• pp.165-170
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• 2015

Purpose: The purpose of this study is to analyze the measurement differences of simple radiographs according to radiation projection angle using a phantom and to propose methods for objective analysis of simple radiographs. Materials and Methods: We took simple radiographs with different projection angles using a C-arm image intensifier and measured five parameters of the foot on the simple radiographic images. Five parameters include lateral tibiocalcaneal angle, lateral talocalcaneal angle, naviculocuboid overlap, lateral talo-first metatarsal angle, and lateral calcaneo-first metatarsal angle. Intraobserver and interobserver reliability were verified, and then intraclass correlations of parameters were analyzed. Results: Radiographic parameters of the foot showed high intraobserver and interobserver reliability. Lateral tibiocalcaneal angle has a strong negative linear relationship with rotation and a moderate negative linear relationship with tilt. Lateral talocalcaneal angle has a moderate positive linear relationship with rotation and a strong positive linear relationship with tilt. Naviculocuboid overlap has a strong positive linear relationship with rotation and a moderate positive linear relationship with tilt. Lateral talo-first metatarsal angle does not have a linear relationship with rotation and a moderate negative linear relationship with tilt. Lateral calcaneo-first metatarsal angle has a moderate positive linear relationship with rotation and tilt. Conclusion: More precise evaluation of the foot with a simple radiograph can be performed by understanding the changes of radiographic parameters according to radiation projection angle.

• Journal of Yeungnam Medical Science
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• v.20 no.2
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• pp.117-128
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• 2003

Thallium-201 scintigraphy is used to discriminate the malignant bone tumor from the benign by qualitatively and quantitatively, and to predict the response of preoperative chemotherapy in osteosarcoma, by comparing the changes of thallium uptake ratio after chemotherapy to the tumor necrosis ratio. Thallium-201 scintigraphy scan should be done prior to surgical biopsy. PICKER Prism 2000 gamma camera with high resolution parallel hole collimator is usually used for scanning. The patient is injected with 2-3mCi of Tl-201 and the early phase is checked in 30 minutes and delayed phase in 3 hours. The scan images are visually evaluated by a blinded nuclear medicine physician. We could evaluate true positive, true negative, false positive and false negative by the comparison of results with those of biopsy, and calculate positive and negative predictive value(%), sensitivity(%), specificity(%) and diagnostic accuracy(%). For the quantitative analysis of thallium uptake, we drew the region of interest on the tumor side and contralateral normal side as mirror image, and calculated the uptake ratio with dividing the amount of gamma count in tumor side by normal side. We could calculate the percent changes of thallium uptake ratio in early and delayed phase, and compare them to the ratio of tumor necrosis. Thallium-201 scintigraphy proved as useful imaging study to discriminate malignant bone tumor from benign, but had exception in giant cell tumor and low grade malignant bone tumors. We can use T1-201 scan to differentiate the benign from the malignant tumor, and to evaluate the response of preoperative chemotherapy or radiotherapy, and to determine the residual tumor or local recurrence. For the better result, we need to have a more detail information about false positive cases and a more objective and quantitative reading technique.

• Transactions on Electrical and Electronic Materials
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• v.11 no.3
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• pp.134-137
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• 2010

We have proposed a transflective liquid crystal display (LCD) driven by the fringe field using a liquid crystal (LC) with a negative dielectric anisotropy. The device used different twist angles of the liquid crystals (LC) in the transmissive (T) and the reflective (R) regions when voltage is applied. With the optimization of the pixel electrode width and the distance between them, the LC directors in the R- and T-regions can be rotated by about $22.5^{\circ}$ and $45^{\circ}$ on an average, respectively. As a result, a high image quality transflective LCD with a single gap, a single gamma, and a wide viewing angle characteristics in both the R- and T- regions can be realized.

• The Journal of Korean Medicine
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• v.34 no.2
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• pp.1-9
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• 2013

Objectives: Considering that homeothermy is a major component of metabolic rate, body temperature might play a role in the pathophysiology of obesity. This study aimed to determine the relationship between abdominal fat distribution and abdominal temperature in Korean, premenopausal, obese women. Methods: Weight and height were measured in 26 premenopausal, obese women to calculate body mass index (BMI). Obesity was defined as a $BMI{\geq}25kg/m^2$. Waist circumference (WC) was also measured as well as abdominal fat by computed tomography (CT) and abdominal temperature by digital infrared thermographic imaging (DITI). Results: Visceral abdominal fat area was found to have a significant negative correlation with the temperature of Guanyuan (CV4, lower abdomen acupoint). We also found the visceral-subcutaneous fat ratio had a significant negative correlation with the temperature of CV4 and Right Tianshu (RST25, lateral navel acupoint). Only visceral fat and its ratio to subcutaneous fat had a significant correlation with abdominal temperature. Subcutaneous fat area and total fat area were not correlated with abdominal temperature. Conclusions: This study suggests that abdominal visceral fat has a significant negative correlation with abdominal temperature. Further study is needed to uncover the relationship between abdominal fat distribution and temperature regulation in obese individuals and to define the role of body temperature in the pathogenesis of obesity.

• Korean Institute of Interior Design Journal
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• v.16 no.5
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• pp.89-97
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• 2007

This study compares, analyzes and reevaluates color conditions and images before and after the execution of the 7th curriculum with elementary schools in Gwang-ju Metropolitan City based on the fact that color among physical environments of elementary classrooms has an important influence on children's emotion and draws problems and aims to accumulate the basic materials for preparing guidelines of improving color environment at general classrooms of elementary schools. Consequently, according to color conditions, major colors on ceiling and wall were high brightness/nigh chroma of Y and YR line regardless of division of grades and other color factors of classroom showed that wall and ceiling used similar colors, but brightness was higher after change than before it. In evaluation of color images, lower grades showed negative color images such as 'common,' 'rustic,' and 'strange' before change, but they showed positive color images after change such as 'clean,' 'unique,' and 'soft'. But, most of higher grades showed negative reactions before change such as 'common,' 'strange,' and 'rustic' and they showed positive reactions after change only in such items as 'clean,' 'warm,' and 'unique', but Indicated negative reactions in remaining items such as 'strange,' 'rustic,' 'stiff,' and 'artificial'. Accordingly, in using colors for lower grade classroom, arrangement of colors through adjustment of brightness and chroma between ceiling, wall and other components based on coloring of high brightness and low chroma of similar colors should be considered and for higher grade classroom, arrangement of colors of unique images of mid-brightness/mid-chroma among warm color lines of similar colors should be examined.

• The Journal of the Korea Contents Association
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• v.18 no.1
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• pp.527-539
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• 2018

The purpose of this study is to analyze the cognizance of sexual minority by applying Q methodology, as well as to provide preliminary data for improving sexual minority's image. The study process let P sample, the study participants, use Q-sorting methodology to sort Q sample, which is composed of statements from July 1 to 20, 2017. 21 participants sorted 32 statements and 3 types of sexual minority cognizance were produced as a result. Those types are 1(N=8), 2(N=5), and 3(N=8), which are type friendly human rights enthusiast, type whereas negative stereotypical, and type neutralist. Friendly human rights enthusiast types agreed to ensure sex minority groups' rights as a general protection, whereas negative stereotypical types had strong discrimination and prejudice towards sex minority groups due to lack of related knowledge. Furthermore, neutralist types showed an objection to negative stereotypes against sex minorities, but they did not entirely agree to homosexuality either.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.2
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• pp.726-741
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• 2022

The purpose of this study is to provide instructive theoretical models for art (music) education institutions especially when unpredictable risks, such as pandemics, occur again. Based on the customer behavior theory of the business-to-business-to-customer (B2B2C) platform, and in combination with the technology acceptance model (TAM) and expectation confirmation model (ECM), this study proposes an online education model from the perspective of art education. The framework is based on the three decision-making processes of the customer, and includes the product owner, content owner, and customer area. This paper highlights the factors that influence customers in making decisions when art education institutions are product owners. Regression analysis was introduced to study the factors influencing the expectation confirmation, and the overall fitting testing and six hypotheses testing of 385 effective samples were performed using the structural equation modeling (SEM). The results show that the course-design and after-service positively influenced the expectation confirmation, and the domain image positively influenced the continuance behavior. Negative emotions skipped the mediator (expectation confirmation) and directly exerted a significant negative impact on customers' willingness to continue system usage (continuance behavior). In addition, expectation confirmation positively influenced continuance behavior. The paths of detailed items comprising course-design, after-service, and negative emotion were also analyzed and discussed. In this path analysis, ordinary art learners did not believe that AI partners can play a very good auxiliary role. The findings contribute to the scope of information systems acting as an art education platform academically, and provide effective and theoretical support for the actual operation of art education institutions.

• Korean Journal of Radiology
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• v.24 no.7
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• pp.626-639
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• 2023

Objective: To investigate the association of clinical, pathologic, and magnetic resonance imaging (MRI) variables with progressive disease (PD) during neoadjuvant chemotherapy (NAC) and distant metastasis-free survival (DMFS) in patients with triple-negative breast cancer (TNBC). Materials and Methods: This single-center retrospective study included 252 women with TNBC who underwent NAC between 2010 and 2019. Clinical, pathologic, and treatment data were collected. Two radiologists analyzed the pre-NAC MRI. After random allocation to the development and validation sets in a 2:1 ratio, we developed models to predict PD and DMFS using logistic regression and Cox proportional hazard regression, respectively, and validated them. Results: Among the 252 patients (age, 48.3 ± 10.7 years; 168 in the development set; 84 in the validation set), PD was occurred in 17 patients and 9 patients in the development and validation sets, respectively. In the clinical-pathologic-MRI model, the metaplastic histology (odds ratio [OR], 8.0; P = 0.032), Ki-67 index (OR, 1.02; P = 0.044), and subcutaneous edema (OR, 30.6; P = 0.004) were independently associated with PD in the development set. The clinical-pathologic-MRI model showed a higher area under the receiver-operating characteristic curve (AUC) than the clinical-pathologic model (AUC: 0.69 vs. 0.54; P = 0.017) for predicting PD in the validation set. Distant metastases occurred in 49 patients and 18 patients in the development and validation sets, respectively. Residual disease in both the breast and lymph nodes (hazard ratio [HR], 6.0; P = 0.005) and the presence of lymphovascular invasion (HR, 3.3; P < 0.001) were independently associated with DMFS. The model consisting of these pathologic variables showed a Harrell's C-index of 0.86 in the validation set. Conclusion: The clinical-pathologic-MRI model, which considered subcutaneous edema observed using MRI, performed better than the clinical-pathologic model for predicting PD. However, MRI did not independently contribute to the prediction of DMFS.